SE8901031L - Nya polypeptider med tillvaextfaktoraktivitet och nukleinsyrasekvenser kodande polypeptiderna - Google Patents

Nya polypeptider med tillvaextfaktoraktivitet och nukleinsyrasekvenser kodande polypeptiderna

Info

Publication number
SE8901031L
SE8901031L SE8901031A SE8901031A SE8901031L SE 8901031 L SE8901031 L SE 8901031L SE 8901031 A SE8901031 A SE 8901031A SE 8901031 A SE8901031 A SE 8901031A SE 8901031 L SE8901031 L SE 8901031L
Authority
SE
Sweden
Prior art keywords
polypeptides
nucleic acid
acid sequences
sequences coding
factor activity
Prior art date
Application number
SE8901031A
Other languages
English (en)
Swedish (sv)
Other versions
SE8901031D0 (sv
Inventor
J P Brown
Original Assignee
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen filed Critical Oncogen
Publication of SE8901031D0 publication Critical patent/SE8901031D0/xx
Publication of SE8901031L publication Critical patent/SE8901031L/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/485Epidermal growth factor [EGF], i.e. urogastrone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/495Transforming growth factor [TGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • C12N15/625DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/24011Poxviridae
    • C12N2710/24111Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
SE8901031A 1988-03-24 1989-03-22 Nya polypeptider med tillvaextfaktoraktivitet och nukleinsyrasekvenser kodande polypeptiderna SE8901031L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17265388A 1988-03-24 1988-03-24

Publications (2)

Publication Number Publication Date
SE8901031D0 SE8901031D0 (sv) 1989-03-22
SE8901031L true SE8901031L (sv) 1989-09-25

Family

ID=22628611

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8901031A SE8901031L (sv) 1988-03-24 1989-03-22 Nya polypeptider med tillvaextfaktoraktivitet och nukleinsyrasekvenser kodande polypeptiderna

Country Status (22)

Country Link
JP (1) JPH0279981A (fi)
KR (1) KR890014743A (fi)
AU (2) AU3169589A (fi)
BE (1) BE1004202A5 (fi)
CH (1) CH681081A5 (fi)
DE (1) DE3910084A1 (fi)
DK (1) DK146789A (fi)
ES (1) ES2013408A6 (fi)
FI (1) FI891308A (fi)
FR (1) FR2632321A1 (fi)
GB (1) GB2219799B (fi)
GR (1) GR1000876B (fi)
HU (1) HUT50501A (fi)
IE (1) IE890950L (fi)
IL (1) IL89673A0 (fi)
IT (1) IT1234961B (fi)
LU (1) LU87489A1 (fi)
NL (1) NL8900724A (fi)
NO (1) NO891273D0 (fi)
NZ (1) NZ228427A (fi)
PT (1) PT90118B (fi)
SE (1) SE8901031L (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0293785A3 (en) * 1987-05-29 1990-05-02 Oncogen Limited Partnership Cloning and expression of simian transforming growth factor-ss1
EP0444961A1 (en) * 1990-03-02 1991-09-04 Bristol-Myers Squibb Company Her3: A novel EGF receptor homolog
EP0739984A1 (en) * 1995-04-26 1996-10-30 San Tumorforschungs-Gmbh Bivalent polypeptides containing at least two domains
US6852506B1 (en) 1996-04-10 2005-02-08 Human Genome Sciences, Inc. Extracellular/epidermal growth factor-like protein
WO1997038002A1 (en) * 1996-04-10 1997-10-16 Human Genome Sciences, Inc. Extracellular/epidermal growth factor-like protein

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0108132A1 (en) * 1982-05-06 1984-05-16 Applied Molecular Genetics Inc. The manufacture and expression of genes for urogastrone and polypeptide analogs thereof
JPS6028994A (ja) * 1983-07-08 1985-02-14 Wakunaga Seiyaku Kk 〔21―ロイシン〕ヒトウロガストロン
WO1985002198A1 (en) * 1983-11-01 1985-05-23 Amgen Microbial expression of type i transforming growth factor, polypeptide analogs thereof and hybrid egf/tgf polypeptides
JP2554459B2 (ja) * 1984-07-02 1996-11-13 アース製薬 株式会社 β−ウロガストロン遺伝子、対応プラスミド組換体及び対応形質転換体
JPS62501071A (ja) * 1984-10-30 1987-04-30 オンコゲン 成長因子活性を有する新規なポリペプチド及び該ポリペプチドをコ−ドする核酸配列
GB8507666D0 (en) * 1985-03-25 1985-05-01 Wellcome Found Epidermal growth factor production
US4743679A (en) * 1986-02-24 1988-05-10 Creative Biomolecules, Inc. Process for producing human epidermal growth factor and analogs thereof
GB2210618B (en) * 1987-10-08 1991-10-16 British Bio Technology Synthetic egf gene
EP0372005A4 (en) * 1987-10-30 1990-06-26 Oncogen EXPRESSION SYSTEMS FOR THE PREPARATION OF POLYPEPTIDES IN PROKARYOTIC CELLS.
EP0314184B1 (en) * 1987-10-30 1995-12-13 Bristol-Myers Squibb Company Expression plasmids

Also Published As

Publication number Publication date
ES2013408A6 (es) 1990-05-01
NO891273D0 (no) 1989-03-22
NL8900724A (nl) 1989-10-16
PT90118B (pt) 1994-07-29
FI891308A0 (fi) 1989-03-20
LU87489A1 (fr) 1989-10-26
HUT50501A (en) 1990-02-28
GB2219799B (en) 1992-10-14
GB8906758D0 (en) 1989-05-10
GR890100185A (en) 1990-01-19
SE8901031D0 (sv) 1989-03-22
DK146789D0 (da) 1989-03-22
NZ228427A (en) 1993-03-26
AU3169589A (en) 1989-09-28
JPH0279981A (ja) 1990-03-20
GB2219799A (en) 1989-12-20
IE890950L (en) 1989-09-24
GR1000876B (el) 1993-03-16
FI891308A (fi) 1989-09-25
IL89673A0 (en) 1989-09-28
DK146789A (da) 1989-09-25
AU2990492A (en) 1993-03-04
CH681081A5 (fi) 1993-01-15
IT8919917A0 (it) 1989-03-24
FR2632321A1 (fr) 1989-12-08
IT1234961B (it) 1992-06-09
BE1004202A5 (fr) 1992-10-13
PT90118A (pt) 1989-11-10
DE3910084A1 (de) 1989-11-16
KR890014743A (ko) 1989-10-25

Similar Documents

Publication Publication Date Title
DE69231223T2 (de) Menschliche pf4a rezeptoren und ihre verwendung
ES539678A0 (es) Procedimiento para preparar un polipeptido ciclico
ES2170962T3 (es) Catalizador acido solido y procedimiento para su obtencion.
DE69730749D1 (de) Verwendung von Metalloxidverbindungen mit Perovskitstruktur
ATE164884T1 (de) Neue sieben-transmembran-rezeptor v28
ATE393222T1 (de) Dcr3 polypeptid, ein tnfr homolog
DE69030579D1 (de) Verfahren zur herstellung von fusionsproteinen
DE50015156D1 (de) Gegen Procalcitonin gerichtete Antikörper, ihre Herstellung und Verwendung
ATE141289T1 (de) Toxoplasma gondii-antigene, ihre herstellung und ihre verwendung
SE8901031L (sv) Nya polypeptider med tillvaextfaktoraktivitet och nukleinsyrasekvenser kodande polypeptiderna
ATE48835T1 (de) Chinolylglycinamidderivate, verfahren zu ihrer herstellung und therapeutische verwendung als psychotrope.
ATE88751T1 (de) Monoklonaler antikoerper spezifisch gegen neutrophilen.
ES2099879T3 (es) 5-oxo-dibenzo(a,d)ciclohepta-1,4-dienos y su uso como agentes retrovirales.
ATE37534T1 (de) Arylethanolhydroxylamine, verfahren zu ihrer herstellung und ihre verwendung zur leistungsfoerderung.
ES8702925A1 (es) Un procedimiento para preparar un polipeptido que tiene ac- tividad de factor de crecimiento
EP0237964A3 (de) 2-Azolylmethyl-2-aryl-1,3-dioxolane und deren Salze,Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung
DE69405928D1 (de) Synthese von Alkyl-Tert-Alkylethern unter Verwendung von Alkylsulfonsäure modifizierten Oxidkatalysatoren
DE69007941D1 (de) Mesophasepech zur Herstellung von Carbonmaterialien.
DE3671603D1 (de) Verfahren zur zucht von babesia canis, verwendung zur herstellung von antigenen und impfstoffen und antigene und impfstoffe gegen piroplasmose.
ATE104266T1 (de) 1-brom-3-chlor-1,2-diaryl-2-propanole, verfahren zur stereoselektiven herstellung der erythro-1- brom-3-chlor-1,2-diaryl-2-propanole und deren umsetzung zu azolylmethyloxiranen.
DE3677270D1 (de) Chinolin-8-carbonsaeureazolide, ein verfahren zu ihrer herstellung und ihre verwendung als herbizide.
ATE33837T1 (de) Azolylmethylcycloacetale, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
RU94016916A (ru) Способ получения 5-[3-(4)-r-1-адамантил]пиримидинов
JPS642586A (en) Western subtype dna and rna molecule of fsme-virus, polypeptide coded by the molecule and its usage
DE10075006I1 (de) Verwendung von (s)(+)-2-aethoxy-4- N- 1-(2piperidino-phenyl)-3-methyl-1-butyl aminocarbonylmethyl-Benzoesaeure zur Herstellung eines Langzeitantidiabetikums

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 8901031-8

Effective date: 19941001