NZ228427A - Dna sequence encoding a polypeptide having similar activity to epidermal growth factor (egf) - Google Patents
Dna sequence encoding a polypeptide having similar activity to epidermal growth factor (egf)Info
- Publication number
- NZ228427A NZ228427A NZ228427A NZ22842789A NZ228427A NZ 228427 A NZ228427 A NZ 228427A NZ 228427 A NZ228427 A NZ 228427A NZ 22842789 A NZ22842789 A NZ 22842789A NZ 228427 A NZ228427 A NZ 228427A
- Authority
- NZ
- New Zealand
- Prior art keywords
- egf
- polypeptide
- growth factor
- sequence encoding
- dna sequence
- Prior art date
Links
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17265388A | 1988-03-24 | 1988-03-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ228427A true NZ228427A (en) | 1993-03-26 |
Family
ID=22628611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ228427A NZ228427A (en) | 1988-03-24 | 1989-03-21 | Dna sequence encoding a polypeptide having similar activity to epidermal growth factor (egf) |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPH0279981A (en) |
| KR (1) | KR890014743A (en) |
| AU (2) | AU3169589A (en) |
| BE (1) | BE1004202A5 (en) |
| CH (1) | CH681081A5 (en) |
| DE (1) | DE3910084A1 (en) |
| DK (1) | DK146789A (en) |
| ES (1) | ES2013408A6 (en) |
| FI (1) | FI891308A (en) |
| FR (1) | FR2632321A1 (en) |
| GB (1) | GB2219799B (en) |
| GR (1) | GR1000876B (en) |
| HU (1) | HUT50501A (en) |
| IE (1) | IE890950L (en) |
| IL (1) | IL89673A0 (en) |
| IT (1) | IT1234961B (en) |
| LU (1) | LU87489A1 (en) |
| NL (1) | NL8900724A (en) |
| NO (1) | NO891273D0 (en) |
| NZ (1) | NZ228427A (en) |
| PT (1) | PT90118B (en) |
| SE (1) | SE8901031L (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0293785A3 (en) * | 1987-05-29 | 1990-05-02 | Oncogen Limited Partnership | Cloning and expression of simian transforming growth factor-ss1 |
| CA2037440A1 (en) * | 1990-03-02 | 1991-09-03 | Gregory D. Plowman | Her3: a novel egf receptor homolog |
| EP0739984A1 (en) * | 1995-04-26 | 1996-10-30 | San Tumorforschungs-Gmbh | Bivalent polypeptides containing at least two domains |
| US6852506B1 (en) | 1996-04-10 | 2005-02-08 | Human Genome Sciences, Inc. | Extracellular/epidermal growth factor-like protein |
| JP2000508531A (en) * | 1996-04-10 | 2000-07-11 | ヒューマン ジノーム サイエンシーズ，インコーポレイテッド | Extracellular / epidermal growth factor-like protein |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0108132A1 (en) * | 1982-05-06 | 1984-05-16 | Applied Molecular Genetics Inc. | The manufacture and expression of genes for urogastrone and polypeptide analogs thereof |
| JPS6028994A (en) * | 1983-07-08 | 1985-02-14 | Wakunaga Seiyaku Kk | (21-leucine) human urogastrone, corresponding gene, corresponding recombinant plasmid, transformed cell and their preparation |
| WO1985002198A1 (en) * | 1983-11-01 | 1985-05-23 | Amgen | Microbial expression of type i transforming growth factor, polypeptide analogs thereof and hybrid egf/tgf polypeptides |
| JP2554459B2 (en) * | 1984-07-02 | 1996-11-13 | アース製薬 株式会社 | β-urogastron gene, corresponding plasmid recombinant and corresponding transformant |
| AU600433B2 (en) * | 1984-10-30 | 1990-08-16 | Oncogen | Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides |
| GB8507666D0 (en) * | 1985-03-25 | 1985-05-01 | Wellcome Found | Epidermal growth factor production |
| US4743679A (en) * | 1986-02-24 | 1988-05-10 | Creative Biomolecules, Inc. | Process for producing human epidermal growth factor and analogs thereof |
| GB2210618B (en) * | 1987-10-08 | 1991-10-16 | British Bio Technology | Synthetic egf gene |
| ES2081801T3 (en) * | 1987-10-30 | 1996-03-16 | Bristol Myers Squibb Co | EXPRESSION PLASMIDS. |
| JP2970811B2 (en) * | 1987-10-30 | 1999-11-02 | オンコゲン ア リミテッド パートナーシップ | Expression systems for preparing polypeptides in prokaryotic cells |
-
1989
- 1989-03-20 IL IL89673A patent/IL89673A0/en unknown
- 1989-03-20 FI FI891308A patent/FI891308A/en not_active IP Right Cessation
- 1989-03-21 NZ NZ228427A patent/NZ228427A/en unknown
- 1989-03-22 NO NO891273A patent/NO891273D0/en unknown
- 1989-03-22 SE SE8901031A patent/SE8901031L/en not_active Application Discontinuation
- 1989-03-22 ES ES8901049A patent/ES2013408A6/en not_active Expired - Lifetime
- 1989-03-22 DK DK146789A patent/DK146789A/en not_active Application Discontinuation
- 1989-03-23 NL NL8900724A patent/NL8900724A/en not_active Application Discontinuation
- 1989-03-23 GR GR890100185A patent/GR1000876B/en unknown
- 1989-03-23 AU AU31695/89A patent/AU3169589A/en not_active Abandoned
- 1989-03-23 GB GB8906758A patent/GB2219799B/en not_active Expired - Fee Related
- 1989-03-23 IE IE890950A patent/IE890950L/en unknown
- 1989-03-24 FR FR8903952A patent/FR2632321A1/en not_active Withdrawn
- 1989-03-24 LU LU87489A patent/LU87489A1/en unknown
- 1989-03-24 KR KR1019890003761A patent/KR890014743A/en not_active Application Discontinuation
- 1989-03-24 IT IT8919917A patent/IT1234961B/en active
- 1989-03-24 BE BE8900329A patent/BE1004202A5/en not_active IP Right Cessation
- 1989-03-24 JP JP1073723A patent/JPH0279981A/en active Pending
- 1989-03-24 HU HU891515A patent/HUT50501A/en unknown
- 1989-03-27 PT PT90118A patent/PT90118B/en active IP Right Grant
- 1989-03-28 DE DE3910084A patent/DE3910084A1/en not_active Withdrawn
- 1989-03-28 CH CH1114/89A patent/CH681081A5/de not_active IP Right Cessation
-
1992
- 1992-12-04 AU AU29904/92A patent/AU2990492A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| FI891308A0 (en) | 1989-03-20 |
| IT1234961B (en) | 1992-06-09 |
| IE890950L (en) | 1989-09-24 |
| GR1000876B (en) | 1993-03-16 |
| KR890014743A (en) | 1989-10-25 |
| ES2013408A6 (en) | 1990-05-01 |
| IL89673A0 (en) | 1989-09-28 |
| PT90118B (en) | 1994-07-29 |
| GB2219799A (en) | 1989-12-20 |
| NL8900724A (en) | 1989-10-16 |
| PT90118A (en) | 1989-11-10 |
| FI891308A (en) | 1989-09-25 |
| GR890100185A (en) | 1990-01-19 |
| GB2219799B (en) | 1992-10-14 |
| DE3910084A1 (en) | 1989-11-16 |
| IT8919917A0 (en) | 1989-03-24 |
| DK146789A (en) | 1989-09-25 |
| BE1004202A5 (en) | 1992-10-13 |
| SE8901031L (en) | 1989-09-25 |
| FR2632321A1 (en) | 1989-12-08 |
| CH681081A5 (en) | 1993-01-15 |
| DK146789D0 (en) | 1989-03-22 |
| LU87489A1 (en) | 1989-10-26 |
| NO891273D0 (en) | 1989-03-22 |
| HUT50501A (en) | 1990-02-28 |
| GB8906758D0 (en) | 1989-05-10 |
| AU2990492A (en) | 1993-03-04 |
| JPH0279981A (en) | 1990-03-20 |
| AU3169589A (en) | 1989-09-28 |
| SE8901031D0 (en) | 1989-03-22 |
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