SE8104132L - Mjuka steroider med antiiflammatorisk verkan - Google Patents

Mjuka steroider med antiiflammatorisk verkan

Info

Publication number
SE8104132L
SE8104132L SE8104132A SE8104132A SE8104132L SE 8104132 L SE8104132 L SE 8104132L SE 8104132 A SE8104132 A SE 8104132A SE 8104132 A SE8104132 A SE 8104132A SE 8104132 L SE8104132 L SE 8104132L
Authority
SE
Sweden
Prior art keywords
soft steroids
flammatory
effects
flammatory effects
steroids
Prior art date
Application number
SE8104132A
Other languages
English (en)
Swedish (sv)
Other versions
SE449106B (sv
Inventor
N S Bodor
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of SE8104132L publication Critical patent/SE8104132L/
Publication of SE449106B publication Critical patent/SE449106B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8104132A 1980-07-10 1981-07-02 Steroid med anti-inflammatorisk verkan samt komposition innehallande denna SE449106B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16845380A 1980-07-10 1980-07-10
US26578581A 1981-05-21 1981-05-21

Publications (2)

Publication Number Publication Date
SE8104132L true SE8104132L (sv) 1982-01-11
SE449106B SE449106B (sv) 1987-04-06

Family

ID=26864131

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8104132A SE449106B (sv) 1980-07-10 1981-07-02 Steroid med anti-inflammatorisk verkan samt komposition innehallande denna

Country Status (17)

Country Link
KR (2) KR860000266B1 ( )
AT (1) AT379816B ( )
AU (1) AU540898B2 ( )
CA (1) CA1174667A ( )
CH (1) CH648856A5 ( )
DE (1) DE3126732A1 ( )
DK (1) DK165837C ( )
ES (2) ES8300785A1 ( )
FI (1) FI71748C ( )
FR (1) FR2486529A1 ( )
GB (1) GB2079755B ( )
IT (1) IT1205446B ( )
NL (1) NL192343C ( )
NO (1) NO163285C ( )
PH (1) PH25874A ( )
PT (1) PT73348B ( )
SE (1) SE449106B ( )

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2137206B (en) * 1980-02-15 1985-04-03 Glaxo Group Ltd Androstane 17-carbothioc acid derivatives
JPS6041607A (ja) * 1983-08-12 1985-03-05 Otsuka Pharmaceut Co Ltd 軟膏基剤
IL78144A0 (en) * 1985-04-04 1986-07-31 Draco Ab Novel androstane-17beta-carboxylic acid esters
SE8501693D0 (sv) * 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
ATE90355T1 (de) * 1987-10-13 1993-06-15 Nicholas S Bodor Weiche steroide mit anti-entzuendungswirkung.
DE4025342A1 (de) * 1990-08-10 1992-02-13 Hoechst Ag In 17-stellung substituierte corticoid-17-alkylcarbonate, verfahren zu deren herstellung und diese enthaltende arzneimittel
ES2215310T3 (es) * 1997-06-30 2004-10-01 Glaxo Group Limited Procedimiento para identificar compuestos que tienen una actividad sistemica reducida.
US6858593B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6777400B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
IL154175A0 (en) 2000-08-05 2003-07-31 Glaxo Group Ltd 17. beta.-carbothioate 17. alpha-arylcarbonyloxyloxy androstane derivatives as anti-inflammatory agents
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6750210B2 (en) 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6858596B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6787532B2 (en) 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
UA77656C2 (en) 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
UA82323C2 (uk) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань
GB0316290D0 (en) 2003-07-11 2003-08-13 Glaxo Group Ltd Novel compounds
ATE517908T1 (de) 2005-01-10 2011-08-15 Glaxo Group Ltd Androstan-17-alpha-carbonat-derivate zur verwendung bei der behandlung allergischer und entzündlicher zustände
AR059216A1 (es) * 2006-01-27 2008-03-19 Sun Pharmaceutical Ind Ltd 11b-hidroxiandrosta-4-eno-3-onas
US7687484B2 (en) * 2006-05-25 2010-03-30 Bodor Nicholas S Transporter enhanced corticosteroid activity
US7691811B2 (en) * 2006-05-25 2010-04-06 Bodor Nicholas S Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
CN101942001B (zh) * 2010-08-24 2013-02-06 山东省医药工业研究所 一种氯替泼诺的提纯方法
CN103183714A (zh) * 2011-12-29 2013-07-03 山东方明药业集团股份有限公司 一种氯替泼诺的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1384372A (en) * 1971-01-20 1975-02-19 Glaxo Lab Ltd Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
GB1514476A (en) * 1974-08-30 1978-06-14 Glaxo Lab Ltd Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates
DE2735110A1 (de) * 1977-08-04 1979-02-15 Hoechst Ag Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung
IT1114534B (it) * 1978-02-08 1986-01-27 Glaxo Group Ltd Steroide anti-infiammatorio della serie dell'androstano composizioni che lo contengono e procedimento per produrlo
US4188385A (en) * 1978-04-05 1980-02-12 Syntex (U.S.A.) Inc. Thioetianic acid derivatives
DE2817988A1 (de) * 1978-04-25 1979-11-08 Hoechst Ag Corticoid 17-alkylcarbonate und verfahren zu deren herstellung

Also Published As

Publication number Publication date
NL8103315A (nl) 1982-02-01
KR830006327A (ko) 1983-09-24
NO812344L (no) 1982-01-11
KR850002759A (ko) 1985-05-15
NL192343B (nl) 1997-02-03
ES8306767A1 (es) 1983-06-16
ES504340A0 (es) 1982-12-01
FI71748C (fi) 1987-02-09
NO163285B (no) 1990-01-22
CA1174667A (en) 1984-09-18
CH648856A5 (de) 1985-04-15
ATA307081A (de) 1985-07-15
FI71748B (fi) 1986-10-31
AT379816B (de) 1986-03-10
PT73348A (en) 1981-08-01
ES8300785A1 (es) 1982-12-01
DK165837C (da) 1993-06-21
DE3126732C2 ( ) 1987-04-30
DK302181A (da) 1982-01-11
NL192343C (nl) 1997-06-04
DK165837B (da) 1993-01-25
PT73348B (en) 1982-09-23
NO163285C (no) 1990-05-02
KR860000452B1 (ko) 1986-04-26
PH25874A (en) 1991-12-02
IT1205446B (it) 1989-03-23
ES514633A0 (es) 1983-06-16
DE3126732A1 (de) 1982-03-25
AU540898B2 (en) 1984-12-06
SE449106B (sv) 1987-04-06
KR860000266B1 (ko) 1986-03-22
GB2079755B (en) 1985-01-30
AU7259181A (en) 1982-01-14
FR2486529A1 (fr) 1982-01-15
IT8105186A0 (it) 1981-07-09
FI812175L (fi) 1982-01-11
FR2486529B1 ( ) 1985-01-04
GB2079755A (en) 1982-01-27

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