SE7710755L - Forfarande for framstellning av foreningar med analgetisk verkan - Google Patents

Forfarande for framstellning av foreningar med analgetisk verkan

Info

Publication number
SE7710755L
SE7710755L SE7710755A SE7710755A SE7710755L SE 7710755 L SE7710755 L SE 7710755L SE 7710755 A SE7710755 A SE 7710755A SE 7710755 A SE7710755 A SE 7710755A SE 7710755 L SE7710755 L SE 7710755L
Authority
SE
Sweden
Prior art keywords
hydrogen
alkyl
primary
associations
preparing
Prior art date
Application number
SE7710755A
Other languages
English (en)
Other versions
SE438339B (sv
Inventor
Jr E L Smithwick
R C A Fredrickson
R T Shuman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SE7710755L publication Critical patent/SE7710755L/sv
Publication of SE438339B publication Critical patent/SE438339B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7710755A 1976-09-27 1977-09-26 Forfarande for framstellning av foreningar med analgetisk verkan SE438339B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72672476A 1976-09-27 1976-09-27
US05/807,849 US4259234A (en) 1976-09-27 1977-06-20 Analgesic compounds

Publications (2)

Publication Number Publication Date
SE7710755L true SE7710755L (sv) 1978-03-28
SE438339B SE438339B (sv) 1985-04-15

Family

ID=27111374

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7710755A SE438339B (sv) 1976-09-27 1977-09-26 Forfarande for framstellning av foreningar med analgetisk verkan

Country Status (27)

Country Link
US (1) US4259234A (sv)
JP (1) JPS5340736A (sv)
AR (1) AR228937A1 (sv)
AT (1) AT359219B (sv)
AU (1) AU513702B2 (sv)
CA (1) CA1201710A (sv)
CH (2) CH636847A5 (sv)
CS (1) CS204011B2 (sv)
DD (1) DD132862A5 (sv)
DE (1) DE2741393A1 (sv)
DK (1) DK148904C (sv)
ES (1) ES462658A1 (sv)
FR (1) FR2365553A1 (sv)
GB (1) GB1586521A (sv)
GR (1) GR69224B (sv)
HK (1) HK52681A (sv)
HU (1) HU180723B (sv)
IE (1) IE45576B1 (sv)
IL (1) IL52872A (sv)
MY (1) MY8200150A (sv)
NL (1) NL7710502A (sv)
NZ (1) NZ185084A (sv)
PL (1) PL111136B1 (sv)
PT (1) PT67026B (sv)
RO (1) RO80379B (sv)
SE (1) SE438339B (sv)
SU (1) SU753358A3 (sv)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261888A (en) * 1976-04-12 1981-04-14 Sandoz Ltd. Organic compounds
SE7709806L (sv) * 1976-09-01 1978-03-02 Coy David Howard Forfarande for framstellning av peptider
HU178001B (en) * 1976-09-16 1982-02-28 Gyogyszekutato Intezet Process for preparing new pentapeptides with morphine-like activity and derivatives thereof
US4322342A (en) * 1977-06-20 1982-03-30 Eli Lilly And Company Analgesic compounds
DE2862327D1 (en) * 1977-07-22 1983-11-10 Wellcome Found Pentapeptide-n-alkylamides and their acid addition salts, methods for preparation of these compounds and pharmaceutical formulations containing them
US4264491A (en) * 1977-10-03 1981-04-28 Eli Lilly And Company Analgesic compounds
FR2424253A1 (fr) * 1978-04-27 1979-11-23 Brun Lab Sa Le Nouveaux derives de peptides analogues des enkephalines, leur procede de preparation et leur application therapeutique
DE2933947A1 (de) * 1979-08-22 1981-03-12 Hoechst Ag, 6000 Frankfurt Neue peptidamide und verfahren zu ihrer herstellung.
US4254024A (en) * 1979-10-16 1981-03-03 Pennwalt Corporation Tetrapeptides and derivatives having opiate activity
US4251439A (en) * 1979-12-17 1981-02-17 Eli Lilly And Company Pharmacologically active peptides
US4283329A (en) * 1979-12-17 1981-08-11 Eli Lilly And Company Pharmacologically active peptides
US4283330A (en) * 1979-12-17 1981-08-11 Eli Lilly And Company Pharmacologically active peptides
US4351763A (en) * 1979-12-17 1982-09-28 Eli Lilly And Company Pharmacologically active peptides
US4265808A (en) * 1979-12-17 1981-05-05 Eli Lilly And Company Pharmacologically active peptides
FR2488253A1 (fr) * 1980-08-08 1982-02-12 Roques Bernard Nouveaux peptides et leur application en therapeutique
US4322339A (en) * 1980-10-20 1982-03-30 Eli Lilly And Company Pharmacologically active peptides
ATE16495T1 (de) * 1981-06-22 1985-11-15 Ici Plc Peptide und pseudopeptide, die zwei substituenten am n-terminus aufweisen.
US4430327A (en) 1982-05-18 1984-02-07 Eli Lilly And Company Method for treating pregnant females for pain and anxiety
DE3915755A1 (de) * 1989-05-13 1990-11-29 Bayer Ag Fungizide mittel sowie substituierte aminosaeureamid-derivate und deren herstellung
DE4102042A1 (de) * 1991-01-24 1992-07-30 Bayer Ag Substituierte aminosaeureamid-derivate deren herstellung und verwendung als fungizide
JPH09173654A (ja) * 1995-12-21 1997-07-08 Ritsuwa Yo 積 木
EP1297830A1 (en) * 2001-09-28 2003-04-02 Flamma Fabbrica Lombarda Ammino Acidi S.p.a. Use of alpha- or beta-amino acids, of the corresponding esters or of dipeptides of these amino acids with histidine derivatives in the prevention or treatment of tissue damage caused by a atmospheric ozone

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1532181A (en) * 1976-02-02 1978-11-15 Beckman Instruments Inc Pentapetides and a method of preparing them
DE2702711A1 (de) * 1976-02-02 1977-08-04 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
NZ183712A (en) * 1976-04-08 1979-10-25 Ici Ltd Polypeptide analogues of enkephalins, and pharmaceutical compositions
SE7709806L (sv) * 1976-09-01 1978-03-02 Coy David Howard Forfarande for framstellning av peptider
HU178001B (en) * 1976-09-16 1982-02-28 Gyogyszekutato Intezet Process for preparing new pentapeptides with morphine-like activity and derivatives thereof
US4178371A (en) * 1977-12-15 1979-12-11 Reckitt & Colman Products Limited Tetrapeptide derivatives

Also Published As

Publication number Publication date
IL52872A (en) 1983-07-31
NZ185084A (en) 1980-11-14
JPS5340736A (en) 1978-04-13
US4259234A (en) 1981-03-31
GB1586521A (en) 1981-03-18
AR228937A1 (es) 1983-05-13
HK52681A (en) 1981-11-06
DK424577A (da) 1978-03-28
AU2856577A (en) 1979-03-15
PT67026B (en) 1979-02-14
AT359219B (de) 1980-10-27
AU513702B2 (en) 1980-12-18
HU180723B (en) 1983-04-29
SE438339B (sv) 1985-04-15
DE2741393A1 (de) 1978-03-30
IE45576L (en) 1978-03-27
CH643533A5 (de) 1984-06-15
RO80379B (ro) 1983-04-30
DE2741393C2 (sv) 1988-03-10
DK148904C (da) 1986-04-14
NL7710502A (nl) 1978-03-29
PL201049A1 (pl) 1979-01-29
RO80379A (ro) 1983-04-29
JPS6254800B2 (sv) 1987-11-17
ES462658A1 (es) 1978-11-01
DK148904B (da) 1985-11-11
PL111136B1 (en) 1980-08-30
PT67026A (en) 1977-10-01
ATA685977A (de) 1980-03-15
FR2365553A1 (fr) 1978-04-21
DD132862A5 (de) 1978-11-15
CS204011B2 (en) 1981-03-31
CA1201710A (en) 1986-03-11
FR2365553B1 (sv) 1980-11-14
SU753358A3 (ru) 1980-07-30
CH636847A5 (de) 1983-06-30
MY8200150A (en) 1982-12-31
GR69224B (sv) 1982-05-10
IE45576B1 (en) 1982-10-06

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