DK424577A - Fremgangsmaade til fremstilling af analgetisk virksomme pentapeptidderivater - Google Patents

Fremgangsmaade til fremstilling af analgetisk virksomme pentapeptidderivater

Info

Publication number
DK424577A
DK424577A DK424577A DK424577A DK424577A DK 424577 A DK424577 A DK 424577A DK 424577 A DK424577 A DK 424577A DK 424577 A DK424577 A DK 424577A DK 424577 A DK424577 A DK 424577A
Authority
DK
Denmark
Prior art keywords
analgetically
efficient
preparing
procedure
pentapeptide derivatives
Prior art date
Application number
DK424577A
Other languages
English (en)
Other versions
DK148904C (da
DK148904B (da
Inventor
E L Smithwick
R C A Frederickson
R T Shuman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK424577A publication Critical patent/DK424577A/da
Publication of DK148904B publication Critical patent/DK148904B/da
Application granted granted Critical
Publication of DK148904C publication Critical patent/DK148904C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK424577A 1976-09-27 1977-09-26 Analogifremgangsmaade til fremstilling af analgetisk virksomme enkephalin-analoge pentapeptidamider eller farmaceutisk acceptable, ikke-toxiske syreadditionssalte deraf DK148904C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US72672476A 1976-09-27 1976-09-27
US72672476 1976-09-27
US05/807,849 US4259234A (en) 1976-09-27 1977-06-20 Analgesic compounds
US80784977 1977-06-20

Publications (3)

Publication Number Publication Date
DK424577A true DK424577A (da) 1978-03-28
DK148904B DK148904B (da) 1985-11-11
DK148904C DK148904C (da) 1986-04-14

Family

ID=27111374

Family Applications (1)

Application Number Title Priority Date Filing Date
DK424577A DK148904C (da) 1976-09-27 1977-09-26 Analogifremgangsmaade til fremstilling af analgetisk virksomme enkephalin-analoge pentapeptidamider eller farmaceutisk acceptable, ikke-toxiske syreadditionssalte deraf

Country Status (27)

Country Link
US (1) US4259234A (da)
JP (1) JPS5340736A (da)
AR (1) AR228937A1 (da)
AT (1) AT359219B (da)
AU (1) AU513702B2 (da)
CA (1) CA1201710A (da)
CH (2) CH636847A5 (da)
CS (1) CS204011B2 (da)
DD (1) DD132862A5 (da)
DE (1) DE2741393A1 (da)
DK (1) DK148904C (da)
ES (1) ES462658A1 (da)
FR (1) FR2365553A1 (da)
GB (1) GB1586521A (da)
GR (1) GR69224B (da)
HK (1) HK52681A (da)
HU (1) HU180723B (da)
IE (1) IE45576B1 (da)
IL (1) IL52872A (da)
MY (1) MY8200150A (da)
NL (1) NL7710502A (da)
NZ (1) NZ185084A (da)
PL (1) PL111136B1 (da)
PT (1) PT67026B (da)
RO (1) RO80379B (da)
SE (1) SE438339B (da)
SU (1) SU753358A3 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261888A (en) * 1976-04-12 1981-04-14 Sandoz Ltd. Organic compounds
NO773013L (no) * 1976-09-01 1978-03-02 David Howard Coy Fremgangsmaate ved fremstilling av methionin-enkefalin-derivater
HU178001B (en) * 1976-09-16 1982-02-28 Gyogyszekutato Intezet Process for preparing new pentapeptides with morphine-like activity and derivatives thereof
US4322342A (en) * 1977-06-20 1982-03-30 Eli Lilly And Company Analgesic compounds
JPS5424850A (en) * 1977-07-22 1979-02-24 Wellcome Found Peptide compound
US4264491A (en) * 1977-10-03 1981-04-28 Eli Lilly And Company Analgesic compounds
FR2424253A1 (fr) * 1978-04-27 1979-11-23 Brun Lab Sa Le Nouveaux derives de peptides analogues des enkephalines, leur procede de preparation et leur application therapeutique
DE2933947A1 (de) * 1979-08-22 1981-03-12 Hoechst Ag, 6000 Frankfurt Neue peptidamide und verfahren zu ihrer herstellung.
US4254024A (en) * 1979-10-16 1981-03-03 Pennwalt Corporation Tetrapeptides and derivatives having opiate activity
US4265808A (en) * 1979-12-17 1981-05-05 Eli Lilly And Company Pharmacologically active peptides
US4283330A (en) * 1979-12-17 1981-08-11 Eli Lilly And Company Pharmacologically active peptides
US4351763A (en) * 1979-12-17 1982-09-28 Eli Lilly And Company Pharmacologically active peptides
US4251439A (en) * 1979-12-17 1981-02-17 Eli Lilly And Company Pharmacologically active peptides
US4283329A (en) * 1979-12-17 1981-08-11 Eli Lilly And Company Pharmacologically active peptides
FR2488253A1 (fr) * 1980-08-08 1982-02-12 Roques Bernard Nouveaux peptides et leur application en therapeutique
US4322339A (en) * 1980-10-20 1982-03-30 Eli Lilly And Company Pharmacologically active peptides
ATE16495T1 (de) * 1981-06-22 1985-11-15 Ici Plc Peptide und pseudopeptide, die zwei substituenten am n-terminus aufweisen.
US4430327A (en) 1982-05-18 1984-02-07 Eli Lilly And Company Method for treating pregnant females for pain and anxiety
DE3915755A1 (de) * 1989-05-13 1990-11-29 Bayer Ag Fungizide mittel sowie substituierte aminosaeureamid-derivate und deren herstellung
DE4102042A1 (de) * 1991-01-24 1992-07-30 Bayer Ag Substituierte aminosaeureamid-derivate deren herstellung und verwendung als fungizide
JPH09173654A (ja) * 1995-12-21 1997-07-08 Ritsuwa Yo 積 木
EP1297830A1 (en) * 2001-09-28 2003-04-02 Flamma Fabbrica Lombarda Ammino Acidi S.p.a. Use of alpha- or beta-amino acids, of the corresponding esters or of dipeptides of these amino acids with histidine derivatives in the prevention or treatment of tissue damage caused by a atmospheric ozone

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1532181A (en) * 1976-02-02 1978-11-15 Beckman Instruments Inc Pentapetides and a method of preparing them
DE2702711A1 (de) * 1976-02-02 1977-08-04 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
NZ183712A (en) * 1976-04-08 1979-10-25 Ici Ltd Polypeptide analogues of enkephalins, and pharmaceutical compositions
NO773013L (no) * 1976-09-01 1978-03-02 David Howard Coy Fremgangsmaate ved fremstilling av methionin-enkefalin-derivater
HU178001B (en) * 1976-09-16 1982-02-28 Gyogyszekutato Intezet Process for preparing new pentapeptides with morphine-like activity and derivatives thereof
US4178371A (en) * 1977-12-15 1979-12-11 Reckitt & Colman Products Limited Tetrapeptide derivatives

Also Published As

Publication number Publication date
ES462658A1 (es) 1978-11-01
RO80379B (ro) 1983-04-30
AR228937A1 (es) 1983-05-13
DE2741393A1 (de) 1978-03-30
NZ185084A (en) 1980-11-14
GR69224B (da) 1982-05-10
PT67026A (en) 1977-10-01
ATA685977A (de) 1980-03-15
JPS5340736A (en) 1978-04-13
SE7710755L (sv) 1978-03-28
PL201049A1 (pl) 1979-01-29
AU513702B2 (en) 1980-12-18
CS204011B2 (en) 1981-03-31
IE45576B1 (en) 1982-10-06
AT359219B (de) 1980-10-27
IL52872A (en) 1983-07-31
HU180723B (en) 1983-04-29
AU2856577A (en) 1979-03-15
US4259234A (en) 1981-03-31
HK52681A (en) 1981-11-06
GB1586521A (en) 1981-03-18
DE2741393C2 (da) 1988-03-10
DK148904C (da) 1986-04-14
SE438339B (sv) 1985-04-15
DD132862A5 (de) 1978-11-15
MY8200150A (en) 1982-12-31
PL111136B1 (en) 1980-08-30
FR2365553A1 (fr) 1978-04-21
CH643533A5 (de) 1984-06-15
JPS6254800B2 (da) 1987-11-17
FR2365553B1 (da) 1980-11-14
RO80379A (ro) 1983-04-29
IE45576L (en) 1978-03-27
CH636847A5 (de) 1983-06-30
SU753358A3 (ru) 1980-07-30
CA1201710A (en) 1986-03-11
NL7710502A (nl) 1978-03-29
PT67026B (en) 1979-02-14
DK148904B (da) 1985-11-11

Similar Documents

Publication Publication Date Title
DK13177A (da) Fremgangsmade til fremstilling af phthalaner
DK116177A (da) Fremgangsmade til fremstilling af hentriakontapeptider
DK13577A (da) Fremgangsmade til fremstilling af polypeptider
DK323677A (da) Fremgangsmade til fremstilling af androstan-17-on-derivater
DK424577A (da) Fremgangsmaade til fremstilling af analgetisk virksomme pentapeptidderivater
DK33177A (da) Fremgangsmade til fremstilling af peptider
DK147068C (da) Analogifremgangsmaade til fremstilling af 1-naphthylmethyl-cinnamyl-aminderivater
DK283177A (da) Fremgangsmade til fremstilling af dipeptidderivater
DK581178A (da) Fremgangsmaade til fremstilling af peptidderivater
DK180277A (da) Fremgangsmade til fremstilling af polyprenylderivater
DK317277A (da) Fremgangsmade til fremstilling af peptidderivater
DK117677A (da) Fremgangsmade til fremstilling af piperidinderivater
DK314177A (da) Fremgangsmade til fremstilling af peptidderivater
DK28377A (da) Fremgangsmade til fremstilling af polypeptidderivater
DK145877A (da) Fremgangsmade til immoblisering af glucoseisomerase
DK314277A (da) Fremgangsmade til fremstilling af peptidderivater
DK329577A (da) Fremgangsmade til fremstilling af derivater af phenoxyhydroxypropylamin
DK566977A (da) Fremgangsmaade til fremstilling af polyenforbindelser
DK385077A (da) Fremgangsmaade til dyrkning af basidiomyceter
DK385677A (da) Fremgangsmaade til fremstilling af benzopyranderivater
DK31977A (da) Fremgangsmade til fremstilling af chromanderivater
DK330077A (da) Fremgangsmade til fremstilling af peptidderivater
DK247877A (da) Fremgangsmade til fremstilling af klavamforbindelser
DK153377A (da) Fremgangsmade til fremstilling af cephemderivater
DK310777A (da) Fremgangsmade til fremstilling af guaiacol-p-isobutyl-hydratropat

Legal Events

Date Code Title Description
PBP Patent lapsed