SE7709482L - Sett att framstella nya 0-(3-amino-2-hydroxipropyl)-amidoximderivat - Google Patents
Sett att framstella nya 0-(3-amino-2-hydroxipropyl)-amidoximderivatInfo
- Publication number
- SE7709482L SE7709482L SE7709482A SE7709482A SE7709482L SE 7709482 L SE7709482 L SE 7709482L SE 7709482 A SE7709482 A SE 7709482A SE 7709482 A SE7709482 A SE 7709482A SE 7709482 L SE7709482 L SE 7709482L
- Authority
- SE
- Sweden
- Prior art keywords
- formula
- amino
- reacting
- amidoxime
- amidoximi
- Prior art date
Links
- SFZULDYEOVSIKM-UHFFFAOYSA-N chembl321317 Chemical compound C1=CC(C(=N)NO)=CC=C1C1=CC=C(C=2C=CC(=CC=2)C(=N)NO)O1 SFZULDYEOVSIKM-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 150000002924 oxiranes Chemical class 0.000 abstract 2
- BRLQWZUYTZBJKN-UHFFFAOYSA-N Epichlorohydrin Chemical compound ClCC1CO1 BRLQWZUYTZBJKN-UHFFFAOYSA-N 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 201000009101 diabetic angiopathy Diseases 0.000 abstract 1
- 201000002249 diabetic peripheral angiopathy Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- AFEQENGXSMURHA-UHFFFAOYSA-N oxiran-2-ylmethanamine Chemical group NCC1CO1 AFEQENGXSMURHA-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU76CI1682A HU177578B (en) | 1976-08-27 | 1976-08-27 | Process for preparing new 0-/3-amino-2-hydroxy-propyl/-amidoxime derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7709482L true SE7709482L (sv) | 1978-02-28 |
| SE435280B SE435280B (sv) | 1984-09-17 |
Family
ID=10994625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7709482A SE435280B (sv) | 1976-08-27 | 1977-08-23 | Sett att framstella nya 0-(3-amino-2-hydroxipropyl)-amidoximderivat |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS5350131A (sv) |
| AT (1) | AT355554B (sv) |
| AU (1) | AU521432B2 (sv) |
| BE (1) | BE858134A (sv) |
| CA (1) | CA1077506A (sv) |
| CH (1) | CH630344A5 (sv) |
| CS (1) | CS204008B2 (sv) |
| DD (1) | DD132433A5 (sv) |
| DE (1) | DE2738589A1 (sv) |
| DK (1) | DK150196C (sv) |
| ES (1) | ES462346A1 (sv) |
| FI (1) | FI68396C (sv) |
| FR (1) | FR2362845A1 (sv) |
| GB (1) | GB1582029A (sv) |
| GR (1) | GR63623B (sv) |
| HU (1) | HU177578B (sv) |
| IL (1) | IL52804A (sv) |
| NL (1) | NL187478C (sv) |
| NO (1) | NO144793C (sv) |
| PL (1) | PL107628B1 (sv) |
| SE (1) | SE435280B (sv) |
| SU (1) | SU730296A3 (sv) |
| YU (2) | YU202377A (sv) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4849522A (en) * | 1983-11-03 | 1989-07-18 | Merrell Dow Pharmaceuticals | Novel alkoxyimino ether derivatives of 5-acyl-2(1H)-pyridinones |
| ZA848428B (en) * | 1983-11-03 | 1985-06-26 | Merrell Pharma Inc | Novel alkoxyimino ether derivatives of 5-acyl-2(1h)-pyridiones |
| US5212314A (en) * | 1983-11-03 | 1993-05-18 | Merrell Dow Pharmaceuticals Inc. | Alkoxyimino ether derivatives of 5-acyl-2(1H)-pyridinones |
| JPH01169445A (ja) * | 1987-12-25 | 1989-07-04 | Fuji Photo Film Co Ltd | 焦点距離切換えカメラ |
| HU207988B (en) * | 1988-10-20 | 1993-07-28 | Biorex Kutato Fejlesztoe Kft | Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components |
| HUT54347A (en) * | 1989-01-10 | 1991-02-28 | Chinoin Gyogyszer Es Vegyeszet | Improved process for producing amidoximes |
| HU222994B1 (hu) | 1995-11-02 | 2004-01-28 | BIOREX Kutató és Fejlesztő Rt. | Hidroxilaminszármazékok és azok alkalmazása sejtek molekuláris chaperon-termelésének fokozására alkalmas gyógyszerkészítmények előállítására |
| HUT78139A (hu) * | 1995-12-22 | 2000-11-28 | BIOREX Kutató és Fejlesztő Rt. | Készítmény, különösen a bőr öregedési folyamatainak mérséklésére |
| HUP9602204D0 (en) * | 1996-08-09 | 1996-10-28 | Biorex Rt | Pharmaceutical compositions for treating diseases connected with the disfunction of the vascular endothelial cells |
| EP1077957B1 (en) | 1998-05-11 | 2004-08-04 | Takeda Chemical Industries, Ltd. | Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity |
| AU5296799A (en) * | 1998-08-03 | 2000-02-28 | N-Gene Kutato Kft. | Pharmaceutical compositions against autoimmune diseases |
| RU2320330C2 (ru) | 2002-01-11 | 2008-03-27 | СиУайТиАрЭкс КОРПОРЕЙШН | Производные карбоксамидина и их использование при лечении заболеваний сосудов |
| HUP0303584A3 (en) | 2003-10-30 | 2009-12-28 | Cytrx Corp | Use of a hydroximic acid halide derivative in the treatment of neurodegenerative diseases |
| KR20230128462A (ko) | 2020-11-19 | 2023-09-05 | 제브라 덴마크 에이/에스 | 아리모클로몰 시트레이트 및 이의 중간체를 제조하기 위한 공정 |
-
1976
- 1976-08-27 HU HU76CI1682A patent/HU177578B/hu unknown
-
1977
- 1977-08-22 AT AT605477A patent/AT355554B/de not_active IP Right Cessation
- 1977-08-23 IL IL7752804A patent/IL52804A/xx unknown
- 1977-08-23 NL NLAANVRAGE7709276,A patent/NL187478C/xx not_active IP Right Cessation
- 1977-08-23 SE SE7709482A patent/SE435280B/sv not_active IP Right Cessation
- 1977-08-24 CS CS775551A patent/CS204008B2/cs unknown
- 1977-08-24 DD DD7700200719A patent/DD132433A5/xx unknown
- 1977-08-24 GR GR54222A patent/GR63623B/el unknown
- 1977-08-25 YU YU02023/77A patent/YU202377A/xx unknown
- 1977-08-25 GB GB35745/77A patent/GB1582029A/en not_active Expired
- 1977-08-26 BE BE180447A patent/BE858134A/xx not_active IP Right Cessation
- 1977-08-26 CH CH1047377A patent/CH630344A5/de not_active IP Right Cessation
- 1977-08-26 DK DK379777A patent/DK150196C/da not_active IP Right Cessation
- 1977-08-26 NO NO772958A patent/NO144793C/no unknown
- 1977-08-26 SU SU772514754A patent/SU730296A3/ru active
- 1977-08-26 FR FR7726070A patent/FR2362845A1/fr active Granted
- 1977-08-26 JP JP10250477A patent/JPS5350131A/ja active Granted
- 1977-08-26 PL PL1977206476A patent/PL107628B1/pl unknown
- 1977-08-26 DE DE19772738589 patent/DE2738589A1/de active Granted
- 1977-08-26 CA CA285,529A patent/CA1077506A/en not_active Expired
- 1977-08-26 AU AU28254/77A patent/AU521432B2/en not_active Expired
- 1977-08-26 FI FI772551A patent/FI68396C/fi not_active IP Right Cessation
- 1977-09-08 ES ES77462346A patent/ES462346A1/es not_active Expired
-
1982
- 1982-10-22 YU YU02377/82A patent/YU237782A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI772551A7 (fi) | 1978-02-28 |
| AU521432B2 (en) | 1982-04-01 |
| ATA605477A (de) | 1979-08-15 |
| NO144793C (no) | 1981-11-11 |
| DK150196C (da) | 1987-07-06 |
| NO144793B (no) | 1981-08-03 |
| FI68396C (fi) | 1985-09-10 |
| GB1582029A (en) | 1980-12-31 |
| DK150196B (da) | 1987-01-05 |
| JPS5350131A (en) | 1978-05-08 |
| SE435280B (sv) | 1984-09-17 |
| NO772958L (no) | 1978-02-28 |
| NL7709276A (nl) | 1978-03-01 |
| AU2825477A (en) | 1979-03-01 |
| NL187478C (nl) | 1991-10-16 |
| FI68396B (fi) | 1985-05-31 |
| JPS6216942B2 (sv) | 1987-04-15 |
| CA1077506A (en) | 1980-05-13 |
| DD132433A5 (de) | 1978-09-27 |
| CH630344A5 (en) | 1982-06-15 |
| PL107628B1 (pl) | 1980-02-29 |
| ES462346A1 (es) | 1978-06-16 |
| DE2738589A1 (de) | 1978-03-02 |
| YU202377A (en) | 1983-12-31 |
| IL52804A (en) | 1981-06-29 |
| SU730296A3 (ru) | 1980-04-25 |
| CS204008B2 (en) | 1981-03-31 |
| FR2362845A1 (fr) | 1978-03-24 |
| AT355554B (de) | 1980-03-10 |
| HU177578B (en) | 1981-11-28 |
| BE858134A (fr) | 1977-12-16 |
| GR63623B (en) | 1979-11-27 |
| FR2362845B1 (sv) | 1981-01-09 |
| DK379777A (da) | 1978-02-28 |
| YU237782A (en) | 1983-12-31 |
| IL52804A0 (en) | 1977-10-31 |
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