IL52804A0 - New 0-(3-amino-2-hydroxy-propyl)-amidoxime derivatives their preparation and pharmaceutical compositions containing them - Google Patents
New 0-(3-amino-2-hydroxy-propyl)-amidoxime derivatives their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL52804A0 IL52804A0 IL7752804A IL5280477A IL52804A0 IL 52804 A0 IL52804 A0 IL 52804A0 IL 7752804 A IL7752804 A IL 7752804A IL 5280477 A IL5280477 A IL 5280477A IL 52804 A0 IL52804 A0 IL 52804A0
- Authority
- IL
- Israel
- Prior art keywords
- propyl
- hydroxy
- amino
- preparation
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU76CI1682A HU177578B (en) | 1976-08-27 | 1976-08-27 | Process for preparing new 0-/3-amino-2-hydroxy-propyl/-amidoxime derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL52804A0 true IL52804A0 (en) | 1977-10-31 |
| IL52804A IL52804A (en) | 1981-06-29 |
Family
ID=10994625
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL7752804A IL52804A (en) | 1976-08-27 | 1977-08-23 | O-(3-amino-2-hydroxy-propyl)-amidoxime derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS5350131A (en) |
| AT (1) | AT355554B (en) |
| AU (1) | AU521432B2 (en) |
| BE (1) | BE858134A (en) |
| CA (1) | CA1077506A (en) |
| CH (1) | CH630344A5 (en) |
| CS (1) | CS204008B2 (en) |
| DD (1) | DD132433A5 (en) |
| DE (1) | DE2738589A1 (en) |
| DK (1) | DK150196C (en) |
| ES (1) | ES462346A1 (en) |
| FI (1) | FI68396C (en) |
| FR (1) | FR2362845A1 (en) |
| GB (1) | GB1582029A (en) |
| GR (1) | GR63623B (en) |
| HU (1) | HU177578B (en) |
| IL (1) | IL52804A (en) |
| NL (1) | NL187478C (en) |
| NO (1) | NO144793C (en) |
| PL (1) | PL107628B1 (en) |
| SE (1) | SE435280B (en) |
| SU (1) | SU730296A3 (en) |
| YU (2) | YU202377A (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5212314A (en) * | 1983-11-03 | 1993-05-18 | Merrell Dow Pharmaceuticals Inc. | Alkoxyimino ether derivatives of 5-acyl-2(1H)-pyridinones |
| ZA848428B (en) * | 1983-11-03 | 1985-06-26 | Merrell Pharma Inc | Novel alkoxyimino ether derivatives of 5-acyl-2(1h)-pyridiones |
| US4849522A (en) * | 1983-11-03 | 1989-07-18 | Merrell Dow Pharmaceuticals | Novel alkoxyimino ether derivatives of 5-acyl-2(1H)-pyridinones |
| JPH01169445A (en) * | 1987-12-25 | 1989-07-04 | Fuji Photo Film Co Ltd | Focal distance switching camera |
| HU207988B (en) * | 1988-10-20 | 1993-07-28 | Biorex Kutato Fejlesztoe Kft | Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components |
| HUT54347A (en) * | 1989-01-10 | 1991-02-28 | Chinoin Gyogyszer Es Vegyeszet | Improved process for producing amidoximes |
| HU222994B1 (en) | 1995-11-02 | 2004-01-28 | BIOREX Kutató és Fejlesztő Rt. | Hydroxylamine derivatives and use thereof in the preparation of a pharmaceutical compositions for enhancing of molecular chaperon production of cells |
| HUT78139A (en) * | 1995-12-22 | 2000-11-28 | BIOREX Kutató és Fejlesztő Rt. | Composition for reducing skin state aging |
| KR100388120B1 (en) | 1998-05-11 | 2003-06-18 | 다케다 야쿠힌 고교 가부시키가이샤 | Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity |
| AU5296799A (en) * | 1998-08-03 | 2000-02-28 | N-Gene Kutato Kft. | Pharmaceutical compositions against autoimmune diseases |
| NZ533795A (en) | 2002-01-11 | 2006-03-31 | Biorex Kutato Fejlesztoe Kft | Carboxamidine derivatives and their use in the treatment of vascular diseases |
| HUP0303584A3 (en) | 2003-10-30 | 2009-12-28 | Cytrx Corp | Use of a hydroximic acid halide derivative in the treatment of neurodegenerative diseases |
| EP4247792A1 (en) | 2020-11-19 | 2023-09-27 | Zevra Denmark A/S | Processes for preparing arimoclomol citrate and intermediates thereof |
-
1976
- 1976-08-27 HU HU76CI1682A patent/HU177578B/en unknown
-
1977
- 1977-08-22 AT AT605477A patent/AT355554B/en not_active IP Right Cessation
- 1977-08-23 SE SE7709482A patent/SE435280B/en not_active IP Right Cessation
- 1977-08-23 IL IL7752804A patent/IL52804A/en unknown
- 1977-08-23 NL NLAANVRAGE7709276,A patent/NL187478C/en not_active IP Right Cessation
- 1977-08-24 DD DD7700200719A patent/DD132433A5/en unknown
- 1977-08-24 CS CS775551A patent/CS204008B2/en unknown
- 1977-08-24 GR GR54222A patent/GR63623B/en unknown
- 1977-08-25 YU YU02023/77A patent/YU202377A/en unknown
- 1977-08-25 GB GB35745/77A patent/GB1582029A/en not_active Expired
- 1977-08-26 CA CA285,529A patent/CA1077506A/en not_active Expired
- 1977-08-26 NO NO772958A patent/NO144793C/en unknown
- 1977-08-26 CH CH1047377A patent/CH630344A5/en not_active IP Right Cessation
- 1977-08-26 DE DE19772738589 patent/DE2738589A1/en active Granted
- 1977-08-26 BE BE180447A patent/BE858134A/en not_active IP Right Cessation
- 1977-08-26 DK DK379777A patent/DK150196C/en not_active IP Right Cessation
- 1977-08-26 JP JP10250477A patent/JPS5350131A/en active Granted
- 1977-08-26 PL PL1977206476A patent/PL107628B1/en unknown
- 1977-08-26 FI FI772551A patent/FI68396C/en not_active IP Right Cessation
- 1977-08-26 SU SU772514754A patent/SU730296A3/en active
- 1977-08-26 FR FR7726070A patent/FR2362845A1/en active Granted
- 1977-08-26 AU AU28254/77A patent/AU521432B2/en not_active Expired
- 1977-09-08 ES ES77462346A patent/ES462346A1/en not_active Expired
-
1982
- 1982-10-22 YU YU02377/82A patent/YU237782A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO772958L (en) | 1978-02-28 |
| ES462346A1 (en) | 1978-06-16 |
| DK150196C (en) | 1987-07-06 |
| GR63623B (en) | 1979-11-27 |
| BE858134A (en) | 1977-12-16 |
| NL187478C (en) | 1991-10-16 |
| IL52804A (en) | 1981-06-29 |
| FR2362845A1 (en) | 1978-03-24 |
| SU730296A3 (en) | 1980-04-25 |
| DK379777A (en) | 1978-02-28 |
| FI68396C (en) | 1985-09-10 |
| DK150196B (en) | 1987-01-05 |
| FI772551A (en) | 1978-02-28 |
| YU202377A (en) | 1983-12-31 |
| HU177578B (en) | 1981-11-28 |
| SE7709482L (en) | 1978-02-28 |
| JPS5350131A (en) | 1978-05-08 |
| YU237782A (en) | 1983-12-31 |
| NO144793C (en) | 1981-11-11 |
| AU521432B2 (en) | 1982-04-01 |
| AT355554B (en) | 1980-03-10 |
| NL7709276A (en) | 1978-03-01 |
| ATA605477A (en) | 1979-08-15 |
| SE435280B (en) | 1984-09-17 |
| CH630344A5 (en) | 1982-06-15 |
| DE2738589A1 (en) | 1978-03-02 |
| CS204008B2 (en) | 1981-03-31 |
| PL107628B1 (en) | 1980-02-29 |
| DD132433A5 (en) | 1978-09-27 |
| AU2825477A (en) | 1979-03-01 |
| GB1582029A (en) | 1980-12-31 |
| FI68396B (en) | 1985-05-31 |
| NO144793B (en) | 1981-08-03 |
| CA1077506A (en) | 1980-05-13 |
| JPS6216942B2 (en) | 1987-04-15 |
| FR2362845B1 (en) | 1981-01-09 |
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