SE462780B - Metod foer mikroinkapsling genom fasseparation av vattenloesliga laekemedel - Google Patents

Metod foer mikroinkapsling genom fasseparation av vattenloesliga laekemedel

Info

Publication number
SE462780B
SE462780B SE8504835A SE8504835A SE462780B SE 462780 B SE462780 B SE 462780B SE 8504835 A SE8504835 A SE 8504835A SE 8504835 A SE8504835 A SE 8504835A SE 462780 B SE462780 B SE 462780B
Authority
SE
Sweden
Prior art keywords
trp
microcapsules
leu
hormone
solvent
Prior art date
Application number
SE8504835A
Other languages
English (en)
Swedish (sv)
Other versions
SE8504835L (sv
SE8504835D0 (sv
Inventor
P Orsolino
R-Y Mauvernay
R Deghenghi
Original Assignee
Debiopharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm Sa filed Critical Debiopharm Sa
Publication of SE8504835D0 publication Critical patent/SE8504835D0/xx
Publication of SE8504835L publication Critical patent/SE8504835L/
Publication of SE462780B publication Critical patent/SE462780B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • B01J13/206—Hardening; drying
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
SE8504835A 1984-10-17 1985-10-16 Metod foer mikroinkapsling genom fasseparation av vattenloesliga laekemedel SE462780B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4979/84A CH660302A5 (fr) 1984-10-17 1984-10-17 Procede de micro-encapsulation en phase heterogene de substances medicamenteuses hydrosolubles.

Publications (3)

Publication Number Publication Date
SE8504835D0 SE8504835D0 (sv) 1985-10-16
SE8504835L SE8504835L (sv) 1986-04-18
SE462780B true SE462780B (sv) 1990-09-03

Family

ID=4285848

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8504835A SE462780B (sv) 1984-10-17 1985-10-16 Metod foer mikroinkapsling genom fasseparation av vattenloesliga laekemedel

Country Status (15)

Country Link
US (1) US4673595A (da)
JP (1) JPS6197216A (da)
AT (1) AT392586B (da)
BE (1) BE903463A (da)
CA (1) CA1259567A (da)
CH (1) CH660302A5 (da)
DE (1) DE3536902A1 (da)
DK (1) DK165355C (da)
ES (1) ES8701495A1 (da)
FR (1) FR2571617B1 (da)
GB (1) GB2165517B (da)
IE (1) IE58245B1 (da)
IT (2) IT1187226B (da)
NL (1) NL192249C (da)
SE (1) SE462780B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4832686A (en) * 1986-06-24 1989-05-23 Anderson Mark E Method for administering interleukin-2
US5000886A (en) * 1987-05-26 1991-03-19 American Cyanamid Company Silicone-hardened pharmaceutical microcapsules and process of making the same
GB2209937B (en) * 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
WO1989003678A1 (en) * 1987-10-30 1989-05-05 Stolle Research & Development Corporation Low residual solvent microspheres and microencapsulation process
US6056992A (en) * 1988-06-02 2000-05-02 Campbell Soup Company Encapsulated additives
IL92344A0 (en) * 1989-01-04 1990-07-26 Gist Brocades Nv Microencapsulation of bioactive substances in biocompatible polymers,microcapsules obtained and pharmaceutical preparation comprising said microcapsules
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
DE4223169C1 (de) 1992-07-10 1993-11-25 Ferring Arzneimittel Gmbh Verfahren zur Mikroverkapselung wasserlöslicher Wirkstoffe
FR2693905B1 (fr) * 1992-07-27 1994-09-02 Rhone Merieux Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
SE512663C2 (sv) 1997-10-23 2000-04-17 Biogram Ab Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
US20030180368A1 (en) * 1998-03-14 2003-09-25 Cenes Drug Delivery Limited Production of microparticles
KR100321854B1 (ko) * 1998-12-30 2002-08-28 동국제약 주식회사 루테이나이징 호르몬 릴리싱 호르몬 동족체를 함유하는 장기 서방출성 미립구 및 그의 제조방법
US6833191B2 (en) * 2001-11-20 2004-12-21 Encap Technologies, Llc Microencapsulated particles and process for manufacturing same
KR100722607B1 (ko) * 2006-05-11 2007-05-28 주식회사 펩트론 분산성 및 주사 투여능이 향상된 서방성 미립구의 제조방법
KR101411349B1 (ko) 2010-12-24 2014-06-25 주식회사 삼양바이오팜 생리활성 펩타이드를 포함하는 마이크로입자 및 그의 제조방법, 및 그를 포함하는 약제학적 조성물
US20160175313A1 (en) 2013-08-06 2016-06-23 Dongkook Pharmaceutical Co., Ltd., Entecavir microspheres and pharmaceutical composition for parenteral administration containing same
CN111315365A (zh) 2017-09-26 2020-06-19 纳奥米有限公司 用于通过双乳液技术制备微粒的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3173878A (en) * 1960-02-26 1965-03-16 Ibm Process of making microcapsules
JPS5134879A (en) * 1974-09-19 1976-03-24 Eisai Co Ltd Bishochukuryushinoseizoho
US4166800A (en) * 1977-08-25 1979-09-04 Sandoz, Inc. Processes for preparation of microspheres
CH649217A5 (de) * 1977-08-25 1985-05-15 Sandoz Ag Bromocriptin enthaltende mikrokapseln.
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides

Also Published As

Publication number Publication date
JPS6197216A (ja) 1986-05-15
NL8502787A (nl) 1986-05-16
DK165355B (da) 1992-11-16
IE58245B1 (en) 1993-08-11
CA1259567A (en) 1989-09-19
NL192249C (nl) 1997-04-03
GB2165517A (en) 1986-04-16
IT8505236A0 (it) 1985-10-15
FR2571617A1 (fr) 1986-04-18
DK165355C (da) 1993-04-05
DE3536902A1 (de) 1986-04-17
NL192249B (nl) 1996-12-02
ES8701495A1 (es) 1986-12-16
DK474585A (da) 1986-04-18
DK474585D0 (da) 1985-10-16
FR2571617B1 (fr) 1988-08-19
IT1187226B (it) 1987-12-16
CH660302A5 (fr) 1987-04-15
ES547915A0 (es) 1986-12-16
SE8504835L (sv) 1986-04-18
US4673595A (en) 1987-06-16
AT392586B (de) 1991-04-25
BE903463A (fr) 1986-02-17
SE8504835D0 (sv) 1985-10-16
IE852459L (en) 1986-04-17
GB2165517B (en) 1988-08-10
DE3536902C2 (da) 1991-08-01
IT8505236A1 (it) 1987-04-15
ATA301185A (de) 1990-10-15
GB8525398D0 (en) 1985-11-20

Similar Documents

Publication Publication Date Title
SE462780B (sv) Metod foer mikroinkapsling genom fasseparation av vattenloesliga laekemedel
US5503851A (en) Microencapsulation of water-soluble medicaments
JP3600252B2 (ja) 医薬物質を持続的に制御して放出できる組成物
EP0263083A1 (en) Coating membrane and compositions prepared therefrom
JP3509105B2 (ja) 活性物質をポリマーで被覆したマイクロカプセルの製法と特にこの方法で得られる新規マイクロカプセル
CA2046830C (en) Drug delivery system involving inter-action between protein or polypeptide and hydrophobic biodegradable polymer
US4637905A (en) Process of preparing microcapsules of lactides or lactide copolymers with glycolides and/or ε-caprolactones
RU2103995C1 (ru) Микрогранулы омепразола и способ их получения
EP0302582A1 (en) Drug delivery system and method of making the same
IE52003B1 (en) Microencapsulation of water soluble polypeptides
JPH0411254B2 (da)
NO180149B (no) Framgangsmåte for framstilling av en blanding for systemisk administrering gjennom slimhinner
KR20080074083A (ko) 난용성 약물을 포함하는 의약용 고형 제제와 그의 제조방법
TW570813B (en) Matrix pellets for greasy, oily or sticky drug substances
EP0301969A1 (fr) Microparticules comportant un polymère biodégradable contrôlant la libération d'un principe actif antimalarique, compositions pharmaceutiques en comprenant et procédé de préparation
JPH0570363A (ja) 持効性の生物分解性微粒子状物およびその調製方法
JPS6143119A (ja) マイクロカプセルおよびそれらの製法ならびに注射組成物
JPH05505628A (ja) 薬物の味のマスキング方法
EP0745383B1 (en) Method for producing an enteric preparation coated with a enteric coating agent powder using a liquid plasticizer
JP2006328060A (ja) 生体吸収性医薬製剤
CH665558A5 (en) Phase sepn. prodn. of microcapsules for water soluble pharmaceuticals - using fluoro-substd. aliphatic hydrocarbon as non-solvent in the hardening stage
EP0908177A1 (en) Procedure to form pharmaceutical compositions in spherical pills or granules of controlled and sustained action that contain as active agent Bromazepam and pharmaceutical compositions obtained by said procedure
JP2003513907A (ja) 錠剤用フィルムコーティング方法
PL183319B1 (pl) Nowe sfery o działaniu spazmolitycznym oraz sposób otrzymywania nowych sfer o działaniu spazmolitycznym
PL183320B1 (pl) Nowe sfery o działaniu spazmolitycznym oraz sposób otrzymywania nowych sfer o działaniu spazmolitycznym

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8504835-3

Format of ref document f/p: F

NUG Patent has lapsed