SE448516B - Forfarande for framstellning av injektionslosningar pa vattenbasis, innehallande en bensodiazepin som aktiv substans - Google Patents
Forfarande for framstellning av injektionslosningar pa vattenbasis, innehallande en bensodiazepin som aktiv substansInfo
- Publication number
- SE448516B SE448516B SE7708059A SE7708059A SE448516B SE 448516 B SE448516 B SE 448516B SE 7708059 A SE7708059 A SE 7708059A SE 7708059 A SE7708059 A SE 7708059A SE 448516 B SE448516 B SE 448516B
- Authority
- SE
- Sweden
- Prior art keywords
- benzodiazepine
- procedure
- active substance
- based solutions
- preparing water
- Prior art date
Links
- SVUOLADPCWQTTE-UHFFFAOYSA-N 1h-1,2-benzodiazepine Chemical compound N1N=CC=CC2=CC=CC=C12 SVUOLADPCWQTTE-UHFFFAOYSA-N 0.000 title 1
- 239000013543 active substance Substances 0.000 title 1
- 229940049706 benzodiazepine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT511176A AT352881B (de) | 1976-07-12 | 1976-07-12 | Verfahren zur herstellung von injektions- loesungen |
CH699477A CH628811A5 (en) | 1976-07-12 | 1977-06-07 | Injection solutions |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7708059L SE7708059L (sv) | 1978-01-13 |
SE448516B true SE448516B (sv) | 1987-03-02 |
Family
ID=25601846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7708059A SE448516B (sv) | 1976-07-12 | 1977-07-11 | Forfarande for framstellning av injektionslosningar pa vattenbasis, innehallande en bensodiazepin som aktiv substans |
Country Status (18)
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2914788A1 (de) * | 1979-04-11 | 1980-10-16 | Nattermann A & Cie | Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung |
CA1173360A (en) * | 1979-06-22 | 1984-08-28 | Jurg Schrank | Pharmaceutical preparations |
US4264583A (en) * | 1979-07-25 | 1981-04-28 | The Procter & Gamble Company | Gallstone dissolution compositions and method |
JPS57163313A (en) * | 1981-03-31 | 1982-10-07 | Nippon Shinyaku Co Ltd | Vitamin e pharmaceutical and its preparation |
JPH0768117B2 (ja) * | 1983-05-06 | 1995-07-26 | ベスター・インコーポレイテツド | 薬剤放出調整用小胞製剤 |
US4649155A (en) * | 1983-07-22 | 1987-03-10 | Hoffmann-La Roche Inc. | Injectable solutions |
JPH0818989B2 (ja) * | 1984-01-12 | 1996-02-28 | 株式会社ミドリ十字 | 脂肪乳剤中のプロスタグランジンの安定化方法 |
CA1264162A (en) * | 1984-03-15 | 1990-01-02 | Manfred Breuninger | Glycerol ether phosphatides |
US5002936A (en) * | 1985-04-12 | 1991-03-26 | Seymour Lieberman | Lipophilic complexes of pharmacologically active inorganic mineral acid esters of organic compounds |
US4831018A (en) * | 1985-05-17 | 1989-05-16 | Smithkline Beckman Corporation | Polyene antibiotic emulsion formulation |
ES2000384A6 (es) * | 1985-08-02 | 1991-03-16 | Merz & Co Gmbh & Co | Metodo para la produccion de una composicion antiviral y antitumoral |
US5023271A (en) * | 1985-08-13 | 1991-06-11 | California Biotechnology Inc. | Pharmaceutical microemulsions |
SE8505047L (sv) * | 1985-10-25 | 1987-04-26 | Nutritional Int Res Inst | Fettemulsion |
CA1319886C (en) | 1987-02-03 | 1993-07-06 | Alberto Ferro | Mixed micelle solutions |
DE3903753A1 (de) * | 1989-02-06 | 1990-08-23 | Schering Ag | Verfahren zur herstellung waessriger mischmicelloesungen |
NZ232865A (en) * | 1989-03-21 | 1992-07-28 | Hoffmann La Roche | A mixed-micelle solution comprising a micelle former and an immunomodulator |
US5085864A (en) * | 1989-10-30 | 1992-02-04 | Abbott Laboratories | Injectable formulation for lipophilic drugs |
DE3938030A1 (de) * | 1989-11-13 | 1991-05-16 | Schering Ag | Verfahren zur herstellung waessriger mischmicelloesungen |
CA2033725C (en) * | 1990-01-24 | 2001-05-29 | Folker Pittrof | Pharmaceutical and cosmetic compositions containing a salt of cholanic acid |
CA2033714A1 (en) * | 1990-01-25 | 1991-07-26 | Alberto Ferro | Pharmaceutical preparations |
FR2663224B1 (fr) * | 1990-06-14 | 1995-01-20 | Applicationes Farmaceuticas Sa | Forme galenique parenterale. |
DE4122661C2 (de) * | 1990-08-06 | 1996-07-11 | Nattermann A & Cie | Pharmazeutisches Produkt zur Behandlung von Pneumocystis-carinii-Pneumonie |
ZA916314B (en) * | 1990-08-17 | 1992-05-27 | Hoffmann La Roche | Use of mixed micelles |
CA2100655C (en) * | 1991-02-08 | 2004-02-03 | Reid W. Von Borstel | Oxypurine nucleosides and their congeners, and acyl derivatives thereof, for improvement of hematopoiesis |
DE4336434A1 (de) * | 1993-10-26 | 1995-04-27 | Hoechst Ag | Pharmazeutische Zubereitung für die parenterale, enterale und dermale Verabreichung von praktisch unlöslichen Arzneistoffen und Verfahren zu ihrer Herstellung |
EP0682943B1 (de) * | 1994-05-20 | 2003-08-20 | GESELLSCHAFT FÜR MEDIZINISCHE FORSCHUNG UND WEITERBILDUNG e.V. GMF | Lormetazepamhaltige Öl-in-Wasser-Emulsion |
GB9426104D0 (en) * | 1994-12-23 | 1995-02-22 | Merck Sharp & Dohme | Use of surfactants and emulsions |
JP2740153B2 (ja) * | 1995-03-07 | 1998-04-15 | エフ・ホフマン−ラ ロシユ アーゲー | 混合ミセル |
US5759445A (en) * | 1995-05-24 | 1998-06-02 | Matsushita Electric Industrial Co., Ltd. | Lipid-dispersed solution and process for producing the same |
GB2326337A (en) | 1997-06-20 | 1998-12-23 | Phares Pharma Holland | Homogeneous lipid compositions for drug delivery |
US6767904B2 (en) | 1998-03-06 | 2004-07-27 | Bringham Young University | Steroid derived antibiotics |
US6350738B1 (en) | 1998-03-06 | 2002-02-26 | Brigham Young University | Steroid derived antibiotics |
PT1389089E (pt) * | 2001-03-27 | 2009-11-30 | Phares Pharm Res Nv | Processo e composição para solubilizar um composto biologicamente activo com uma baixa solubilidade em água |
WO2005095950A1 (en) * | 2004-03-30 | 2005-10-13 | Pfizer Products Inc. | Method and device for evaluation of pharmaceutical compositions |
PL1758590T3 (pl) * | 2004-05-19 | 2012-03-30 | Los Angeles Biomedical Res Inst Harbor Ucla Medical Ct | Zastosowanie detergentu do niechirurgicznego usuwania tłuszczu |
US20060127468A1 (en) * | 2004-05-19 | 2006-06-15 | Kolodney Michael S | Methods and related compositions for reduction of fat and skin tightening |
US7754230B2 (en) * | 2004-05-19 | 2010-07-13 | The Regents Of The University Of California | Methods and related compositions for reduction of fat |
WO2008065502A1 (en) * | 2006-11-29 | 2008-06-05 | Pfizer Products Inc. | Pharmaceutical compositions based on a) nanoparticles comprising enteric polymers and b) casein |
US20100119612A1 (en) * | 2007-04-17 | 2010-05-13 | Bend Research, Inc | Nanoparticles comprising non-crystalline drug |
WO2008135855A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer |
US20100080852A1 (en) * | 2007-05-03 | 2010-04-01 | Ronald Arthur Beyerinck | Phamaceutical composition comprising nanoparticles and casein |
WO2008135828A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
US8974827B2 (en) * | 2007-06-04 | 2015-03-10 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
US9545384B2 (en) | 2007-06-04 | 2017-01-17 | Bend Research, Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate |
EP2178518A2 (en) * | 2007-07-13 | 2010-04-28 | Bend Research, Inc | Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers |
US9233078B2 (en) * | 2007-12-06 | 2016-01-12 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer |
WO2009073215A1 (en) * | 2007-12-06 | 2009-06-11 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
US8101593B2 (en) | 2009-03-03 | 2012-01-24 | Kythera Biopharmaceuticals, Inc. | Formulations of deoxycholic acid and salts thereof |
CN102058528B (zh) * | 2009-11-13 | 2012-12-12 | 中国科学院上海药物研究所 | 一种黄豆苷元胶束及其制备方法 |
GB2480632A (en) | 2010-05-25 | 2011-11-30 | Kythera Biopharmaceuticals Inc | Preparation of 12-keto and 12-alpha-hydroxy steroids |
MX363465B (es) | 2011-02-18 | 2019-03-25 | Kythera Biopharmaceuticals Inc | Tratamiento de la grasa submental. |
US8653058B2 (en) | 2011-04-05 | 2014-02-18 | Kythera Biopharmaceuticals, Inc. | Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits |
CA2875208C (en) * | 2012-05-31 | 2018-07-10 | Terumo Kabushiki Kaisha | Ph-sensitive carrier and preparation method thereof, and ph sensitive drug and ph sensitive drug composition each containing the carrier, and culture method using the same |
US9321749B1 (en) | 2012-07-25 | 2016-04-26 | Globavir Biosciences, Inc. | Heterocyclic compounds and uses thereof |
CA3178035A1 (en) | 2012-12-24 | 2014-07-03 | Neurogastrx, Inc. | Methods for treating gi tract disorders |
WO2015200369A1 (en) | 2014-06-24 | 2015-12-30 | Neurogastrx, Inc. | Prodrugs of metopimazine |
CN110876719B (zh) * | 2018-09-06 | 2022-08-09 | 中国人民解放军军事科学院军事医学研究院 | 一种维生素k1注射剂及其制备方法 |
US10836757B1 (en) | 2020-04-02 | 2020-11-17 | Neurogastrx, Inc. | Polymorphic forms of metopimazine |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE575616C (de) * | 1928-12-14 | 1933-04-29 | Hans Much Dr | Verfahren zur Herstellung bestaendiger, klarer, waessriger Loesungen von Lipoiden, Fetten oder Harzen |
GB706607A (en) | 1951-07-31 | 1954-03-31 | Roche Products Ltd | Process for the manufacture of dispersable solutions of fat soluble vitamins |
DE932083C (de) * | 1954-03-31 | 1955-08-22 | Upha Chem Pharm Praeparate G M | Verfahren zur Herstellung stabiler waessriger Injektionsloesungen von 2-Methyl-5, 8-dimethoxy-furanochromon |
DE1089510B (de) * | 1959-03-23 | 1960-09-22 | Rudolf Reiss Dr | Verfahren zur Herstellung waessriger, injizierbarer Loesungen von 2-Methoxy-4-allylphenoxyessigsaeure-N, N-Diaethylamid |
US3044931A (en) * | 1960-01-27 | 1962-07-17 | Geigy Chem Corp | Aryloxy acetic acid amides: process for parenteral application |
NL260444A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1960-12-05 | |||
US3639597A (en) * | 1968-02-02 | 1972-02-01 | Merck & Co Inc | Pharmaceutical compositions containing cholanic acid conjugates |
GB1317184A (en) * | 1969-06-20 | 1973-05-16 | Glaxo Lab Ltd | Steroid-containing pharmaceutical preparations |
US3900561A (en) * | 1970-12-17 | 1975-08-19 | Glaxo Lab Ltd | Pharmaceutical compositions |
US3917830A (en) * | 1970-12-17 | 1975-11-04 | Glaxo Lab Ltd | Steroidal anaesthetic composition for intraveneous injection |
AU461715B2 (en) * | 1972-01-21 | 1975-05-19 | American Home Products Corporation | Parenteral benzodiazepine compositions |
US4017616A (en) * | 1972-01-21 | 1977-04-12 | American Home Products Corporation | Parenteral benzodiazepine compositions |
DE2315609A1 (de) * | 1973-03-29 | 1974-10-17 | Holzhueter Hermann | Verfahren zum loesen von indomethacin in wasser und eine indomethacin enthaltende pharmazeutische zubereitung zur parenteralen applikation |
DE2433173C3 (de) * | 1974-07-10 | 1980-02-07 | J. Pfrimmer & Co, 8520 Erlangen | Verwendung von Cholansaurederivaten |
-
1977
- 1977-06-29 IT IT25194/77A patent/IT1202370B/it active Protection Beyond IP Right Term
- 1977-07-05 NZ NZ184564A patent/NZ184564A/xx unknown
- 1977-07-05 IL IL52458A patent/IL52458A/xx unknown
- 1977-07-06 IE IE1403/77A patent/IE46037B1/en not_active IP Right Cessation
- 1977-07-06 DE DE19772730570 patent/DE2730570A1/de active Granted
- 1977-07-07 AU AU26846/77A patent/AU517249B2/en not_active Expired
- 1977-07-07 FR FR7720957A patent/FR2358161A1/fr active Granted
- 1977-07-08 LU LU77708A patent/LU77708A1/xx unknown
- 1977-07-08 JP JP52081110A patent/JPS6051448B2/ja not_active Expired
- 1977-07-08 US US05/813,913 patent/US4158707A/en not_active Expired - Lifetime
- 1977-07-08 CA CA282,347A patent/CA1082596A/en not_active Expired
- 1977-07-08 NL NLAANVRAGE7707641,A patent/NL189072C/xx not_active IP Right Cessation
- 1977-07-11 GB GB29006/77A patent/GB1587076A/en not_active Expired
- 1977-07-11 DK DK314777A patent/DK149483C/da not_active Application Discontinuation
- 1977-07-11 SE SE7708059A patent/SE448516B/xx not_active IP Right Cessation
- 1977-07-12 PH PH19986A patent/PH16333A/en unknown
-
1978
- 1978-12-28 FR FR7836690A patent/FR2423219A1/fr active Granted
-
1984
- 1984-03-22 HK HK265/84A patent/HK26584A/xx unknown
-
1985
- 1985-12-30 MY MY263/85A patent/MY8500263A/xx unknown
-
1997
- 1997-03-12 LU LU90037C patent/LU90037I2/fr unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE448516B (sv) | Forfarande for framstellning av injektionslosningar pa vattenbasis, innehallande en bensodiazepin som aktiv substans | |
DK138622B (da) | Absorberende pude, fortrinsvis til en engangsble. | |
SE421308B (sv) | Bensoylureido-difenyletrar till anvendning som insekticider | |
NO145443C (no) | Papirmaskin, saerlig for fremstilling av tissuepapir | |
NL7713817A (nl) | Nieuwe, therapeutisch werkzame piperazinederiva- ten, werkwijzen ter bereiding hiervan en farma- ceutische preparaten die deze verbindingen be- vatten. | |
BR7603584A (pt) | Eixo telescopico,especialmente para maquinas agricolas | |
NL7710502A (nl) | Werkwijze ter bereiding van farmaceutische pre- paraten alsmede werkwijze ter bereiding van nieuwe, analgetisch werkzame verbindingen. | |
NO149105C (no) | Benzoylureido-nitro-difenyletere for anvendelse som insekticider | |
SE431653B (sv) | Forfarande for framstellning av 2,3-dihydro-imidazo/2,1-b/tiazolderivat | |
SE7808059L (sv) | Forfarande for framstellning av 1,2,4-triazin-5-on-derivat | |
SE421414B (sv) | 2', 3,6'-triklor-4-cyano-4'bensoylureidodofenyletrar till anvendning som insekticider | |
SE7807024L (sv) | Injektions-matris, som hjelpmedel for diabetiker | |
SE431213B (sv) | N-fosfonometylglycinderivat till anvendning som herbicider | |
NO770957L (no) | Piperidinforbindelser for orale preparater. | |
SE424975B (sv) | Fergverk for roterande tryckpressar | |
FI840367A0 (fi) | Vid framstaellning av som mellanprodukter vid terapeutiskt anvaendbara 2 -acetoximetyl-2 -metyl-(5r)-penam-3 -karboxyksyra-1,1-dioxidderivat anvaenbara 2 -acetoxymetyl-2 -metyl-(5r)-penam-3 -karboxylsyraderivat | |
SE439631B (sv) | Forfarande for framstellning av 3,4-dihydrokarbostyrilderivat | |
SE441105B (sv) | Forfarande for framstellning av en amorf, lett, hart fastsittande fosfatbeleggning | |
NO147423C (no) | Fremgangsmaate for fremstilling av 2-piperazinyl-kinazolinderivater. | |
SE7701468L (sv) | Bojstyv griparvagn, serskilt avsedd for offsettryckmaskiner | |
NO149471C (no) | Analogifremgangsmaate for fremstilling av farmasoeytisk aktive tetracyklononanderivater | |
NO153951C (no) | Fremgangsmaate for fremstilling av en farmasoeytisk tilberedning som inneholder 8-metoksy-furo-(3[ ,2[:6,7)-cumarin. | |
SE431543B (sv) | Analogiforfarande for framstellning av 1,4-bensodiazepinderivat | |
SE7504413L (sv) | Forfarande for framstellning av en ny antibiotisk substans. | |
SE426947B (sv) | Forfarande for framstellning av 3,5,5-trimetyl-hexanoyl-ferrocen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAL | Patent in force |
Ref document number: 7708059-6 Format of ref document f/p: F |
|
NUG | Patent has lapsed |
Ref document number: 7708059-6 Format of ref document f/p: F |