JPS57163313A - Vitamin e pharmaceutical and its preparation - Google Patents
Vitamin e pharmaceutical and its preparationInfo
- Publication number
- JPS57163313A JPS57163313A JP4888881A JP4888881A JPS57163313A JP S57163313 A JPS57163313 A JP S57163313A JP 4888881 A JP4888881 A JP 4888881A JP 4888881 A JP4888881 A JP 4888881A JP S57163313 A JPS57163313 A JP S57163313A
- Authority
- JP
- Japan
- Prior art keywords
- vitamin
- lecithin
- homolog
- water
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
PURPOSE: To obtain a pharmaceutical, capable of rapidly giving a high concentration of vitamin E in the blood, and suitable for intravenous injection, by incorporating a vitamin E homolog slightly soluble in water with lecithin and another substance, mixing the mixture with water, treating the resultant mixture with ultrasonic waves, and filtering the treated mixture.
CONSTITUTION: A vitamin E homolog is mixed with lecithin and if necessary glycerol, fat or oil, and then mixed with water and then treated with ultrasonic waves and emulsified. The resultant emulsion is then filtered through a membranous filter to give a vitamin E pharamcutical suitable for the intravenous injection. The operations are carried out aseptically under light shielding conditions in a nitrogen gas stream. Soybean lecithin or egg yolk lecithin is preferred as the lecithin. The amounts of the components as follows based on that of the vitamin E homolog: 2W5 times lecithin, 3W6 times glycerol and about 20W30 times fat or oil.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4888881A JPS57163313A (en) | 1981-03-31 | 1981-03-31 | Vitamin e pharmaceutical and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4888881A JPS57163313A (en) | 1981-03-31 | 1981-03-31 | Vitamin e pharmaceutical and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57163313A true JPS57163313A (en) | 1982-10-07 |
Family
ID=12815809
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4888881A Pending JPS57163313A (en) | 1981-03-31 | 1981-03-31 | Vitamin e pharmaceutical and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57163313A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6470413A (en) * | 1987-05-15 | 1989-03-15 | Santen Pharmaceutical Co Ltd | Aqueous preparation of vitamin e |
US5023271A (en) * | 1985-08-13 | 1991-06-11 | California Biotechnology Inc. | Pharmaceutical microemulsions |
JP2002532564A (en) * | 1998-12-21 | 2002-10-02 | フレセニウス・カビ・オーストリア・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Oil-in-water emulsion having protective action against damage to human organs due to peroxidation, production and use thereof |
EP1952700A1 (en) | 2002-04-05 | 2008-08-06 | Nestec S.A. | Method of improving absorption of vitamin E by a pet animal |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50126821A (en) * | 1974-02-14 | 1975-10-06 | ||
DE2730570A1 (en) * | 1976-07-12 | 1978-01-19 | Hoffmann La Roche | INJECTION SOLUTIONS |
-
1981
- 1981-03-31 JP JP4888881A patent/JPS57163313A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50126821A (en) * | 1974-02-14 | 1975-10-06 | ||
DE2730570A1 (en) * | 1976-07-12 | 1978-01-19 | Hoffmann La Roche | INJECTION SOLUTIONS |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5023271A (en) * | 1985-08-13 | 1991-06-11 | California Biotechnology Inc. | Pharmaceutical microemulsions |
JPS6470413A (en) * | 1987-05-15 | 1989-03-15 | Santen Pharmaceutical Co Ltd | Aqueous preparation of vitamin e |
JP2002532564A (en) * | 1998-12-21 | 2002-10-02 | フレセニウス・カビ・オーストリア・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | Oil-in-water emulsion having protective action against damage to human organs due to peroxidation, production and use thereof |
EP1952700A1 (en) | 2002-04-05 | 2008-08-06 | Nestec S.A. | Method of improving absorption of vitamin E by a pet animal |
EP1952700B1 (en) | 2002-04-05 | 2017-05-17 | Nestec S.A. | Method of improving absorption of vitamin E by a pet animal |
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