JPS57163313A - Vitamin e pharmaceutical and its preparation - Google Patents

Vitamin e pharmaceutical and its preparation

Info

Publication number
JPS57163313A
JPS57163313A JP4888881A JP4888881A JPS57163313A JP S57163313 A JPS57163313 A JP S57163313A JP 4888881 A JP4888881 A JP 4888881A JP 4888881 A JP4888881 A JP 4888881A JP S57163313 A JPS57163313 A JP S57163313A
Authority
JP
Japan
Prior art keywords
vitamin
lecithin
homolog
water
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4888881A
Other languages
Japanese (ja)
Inventor
Ryohei Hori
Shikifumi Kitazawa
Masato Yasuhara
Hiroshi Tanimura
Yoshinori Hikasa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Priority to JP4888881A priority Critical patent/JPS57163313A/en
Publication of JPS57163313A publication Critical patent/JPS57163313A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To obtain a pharmaceutical, capable of rapidly giving a high concentration of vitamin E in the blood, and suitable for intravenous injection, by incorporating a vitamin E homolog slightly soluble in water with lecithin and another substance, mixing the mixture with water, treating the resultant mixture with ultrasonic waves, and filtering the treated mixture.
CONSTITUTION: A vitamin E homolog is mixed with lecithin and if necessary glycerol, fat or oil, and then mixed with water and then treated with ultrasonic waves and emulsified. The resultant emulsion is then filtered through a membranous filter to give a vitamin E pharamcutical suitable for the intravenous injection. The operations are carried out aseptically under light shielding conditions in a nitrogen gas stream. Soybean lecithin or egg yolk lecithin is preferred as the lecithin. The amounts of the components as follows based on that of the vitamin E homolog: 2W5 times lecithin, 3W6 times glycerol and about 20W30 times fat or oil.
COPYRIGHT: (C)1982,JPO&Japio
JP4888881A 1981-03-31 1981-03-31 Vitamin e pharmaceutical and its preparation Pending JPS57163313A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4888881A JPS57163313A (en) 1981-03-31 1981-03-31 Vitamin e pharmaceutical and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4888881A JPS57163313A (en) 1981-03-31 1981-03-31 Vitamin e pharmaceutical and its preparation

Publications (1)

Publication Number Publication Date
JPS57163313A true JPS57163313A (en) 1982-10-07

Family

ID=12815809

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4888881A Pending JPS57163313A (en) 1981-03-31 1981-03-31 Vitamin e pharmaceutical and its preparation

Country Status (1)

Country Link
JP (1) JPS57163313A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6470413A (en) * 1987-05-15 1989-03-15 Santen Pharmaceutical Co Ltd Aqueous preparation of vitamin e
US5023271A (en) * 1985-08-13 1991-06-11 California Biotechnology Inc. Pharmaceutical microemulsions
JP2002532564A (en) * 1998-12-21 2002-10-02 フレセニウス・カビ・オーストリア・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Oil-in-water emulsion having protective action against damage to human organs due to peroxidation, production and use thereof
EP1952700A1 (en) 2002-04-05 2008-08-06 Nestec S.A. Method of improving absorption of vitamin E by a pet animal

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50126821A (en) * 1974-02-14 1975-10-06
DE2730570A1 (en) * 1976-07-12 1978-01-19 Hoffmann La Roche INJECTION SOLUTIONS

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50126821A (en) * 1974-02-14 1975-10-06
DE2730570A1 (en) * 1976-07-12 1978-01-19 Hoffmann La Roche INJECTION SOLUTIONS

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5023271A (en) * 1985-08-13 1991-06-11 California Biotechnology Inc. Pharmaceutical microemulsions
JPS6470413A (en) * 1987-05-15 1989-03-15 Santen Pharmaceutical Co Ltd Aqueous preparation of vitamin e
JP2002532564A (en) * 1998-12-21 2002-10-02 フレセニウス・カビ・オーストリア・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Oil-in-water emulsion having protective action against damage to human organs due to peroxidation, production and use thereof
EP1952700A1 (en) 2002-04-05 2008-08-06 Nestec S.A. Method of improving absorption of vitamin E by a pet animal
EP1952700B1 (en) 2002-04-05 2017-05-17 Nestec S.A. Method of improving absorption of vitamin E by a pet animal

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