SE445216B - Nya antihypertensiva pyridazinylhydrazoner - Google Patents

Nya antihypertensiva pyridazinylhydrazoner

Info

Publication number
SE445216B
SE445216B SE7806577A SE7806577A SE445216B SE 445216 B SE445216 B SE 445216B SE 7806577 A SE7806577 A SE 7806577A SE 7806577 A SE7806577 A SE 7806577A SE 445216 B SE445216 B SE 445216B
Authority
SE
Sweden
Prior art keywords
carbon atoms
general formula
hydrogen
acid
alkyl
Prior art date
Application number
SE7806577A
Other languages
English (en)
Swedish (sv)
Other versions
SE7806577L (sv
Inventor
G Szilagyi
E Kasztreiner
J Kosary
P Matyus
Z Huszti
G Cseh
A Kenessey
L Tardos
E Kosa
L Jaszlits
S Elek
I Elekes
I Polgari
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of SE7806577L publication Critical patent/SE7806577L/xx
Publication of SE445216B publication Critical patent/SE445216B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/22—Nitrogen and oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7806577A 1977-06-13 1978-06-05 Nya antihypertensiva pyridazinylhydrazoner SE445216B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77GO1372A HU176972B (hu) 1977-06-13 1977-06-13 Sposob poluchenija novykh proizvodnykh piridazinil-gidrazona

Publications (2)

Publication Number Publication Date
SE7806577L SE7806577L (sv) 1978-12-14
SE445216B true SE445216B (sv) 1986-06-09

Family

ID=10996833

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7806577A SE445216B (sv) 1977-06-13 1978-06-05 Nya antihypertensiva pyridazinylhydrazoner

Country Status (24)

Country Link
US (2) US4259328A (da)
JP (2) JPS6019754B2 (da)
AT (1) AT359075B (da)
AU (1) AU521639B2 (da)
BE (1) BE868027A (da)
BG (2) BG33284A3 (da)
CA (1) CA1077937A (da)
CH (1) CH638189A5 (da)
CS (1) CS244653B2 (da)
DD (1) DD138901A5 (da)
DE (1) DE2825861A1 (da)
DK (1) DK148683C (da)
ES (1) ES470751A1 (da)
FI (1) FI64149C (da)
FR (1) FR2394535A1 (da)
GB (1) GB2000125B (da)
HU (1) HU176972B (da)
IL (1) IL54899A (da)
NL (1) NL7806381A (da)
NO (1) NO154392C (da)
PL (2) PL113210B1 (da)
SE (1) SE445216B (da)
SU (3) SU867300A3 (da)
YU (1) YU40710B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5470229A (en) * 1977-11-11 1979-06-05 Toray Ind Inc Separation of 8c aromatic hydrocarbons
HU178552B (en) * 1978-07-14 1982-05-28 Gyogyszerkutato Intezet Process for producing new blood pressure lowering composition of increased activity
HU179191B (en) * 1979-05-07 1982-09-28 Gyogyszerkutato Intezet New process for preparing 6-/substituted amino/-3-pyridazinyl-hydrazines and salts thereof
FR2668151A1 (fr) * 1990-10-23 1992-04-24 Rhone Poulenc Agrochimie Composes a groupe triazolopyridazine leurs preparations et compositions herbicides les contenant.
US5417208A (en) * 1993-10-12 1995-05-23 Arrow International Investment Corp. Electrode-carrying catheter and method of making same
KR100607838B1 (ko) * 1997-10-27 2006-08-04 뉴로서치 에이/에스 니코틴 작용성 아세틸콜린 수용체상의 콜린 작용성 리간드로서의 호모피페라진 유도체 및 이를 포함하는 약제학적 조성물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1157642A (en) * 1965-10-08 1969-07-09 Lepetit Spa 3-Hydrazino-6-Amino-Pyridazines
US3528969A (en) * 1967-11-30 1970-09-15 Sandoz Ag Benzylidene hydrazones
US3642792A (en) * 1968-02-26 1972-02-15 Lepetit Spa Pyridazine derivatives
US3706744A (en) * 1970-11-16 1972-12-19 Sandoz Ag Hydrazone derivatives of 3-substituted amino-6-hydrazino pyridazines
US3717632A (en) * 1971-01-29 1973-02-20 Sandoz Ag Substituted-3-hydrazino pyridazines
US3717635A (en) * 1971-02-22 1973-02-20 Sandoz Ag Hydrazino and substituted hydrazino pyridazine-n-oxides
DE2202744A1 (de) * 1972-01-21 1973-07-26 Boehringer Mannheim Gmbh Nitrofuryl-triazolo eckige klammer auf 4,3-b eckige klammer zu-pyridazin-amide
US3978057A (en) * 1972-04-05 1976-08-31 Sandoz, Inc. Substituted amino-hydrazinopyridazines
ES431009A1 (es) * 1974-05-09 1976-10-16 Isf Spa Procedimiento para la preparacion de derivados de 3-benci- lidenhidracino-6-aminopiridacina.
FR2306697A1 (fr) * 1975-04-10 1976-11-05 Sogeras Nouvelles pyrimidines utilisables comme medicaments antidiabetiques et hypocholesterolemiants

Also Published As

Publication number Publication date
DE2825861C2 (da) 1989-10-05
AU3706678A (en) 1979-12-20
PL113210B1 (en) 1980-11-29
GB2000125B (en) 1982-05-06
BG33284A3 (en) 1983-01-14
AU521639B2 (en) 1982-04-22
AT359075B (de) 1980-10-27
SU936811A3 (ru) 1982-06-15
NO154392B (no) 1986-06-02
US4259328A (en) 1981-03-31
DK148683B (da) 1985-09-02
US4308386A (en) 1981-12-29
BE868027A (fr) 1978-12-12
FI781886A (fi) 1978-12-14
SU867300A3 (ru) 1981-09-23
PL207592A1 (pl) 1979-05-07
JPS5762267A (en) 1982-04-15
GB2000125A (en) 1979-01-04
FI64149C (fi) 1983-10-10
NO782042L (no) 1978-12-14
FR2394535B1 (da) 1982-06-25
JPS6021983B2 (ja) 1985-05-30
CH638189A5 (de) 1983-09-15
FI64149B (fi) 1983-06-30
IL54899A (en) 1982-05-31
PL113062B1 (en) 1980-11-29
SU890977A3 (ru) 1981-12-15
JPS5416486A (en) 1979-02-07
ATA424078A (de) 1980-03-15
SE7806577L (sv) 1978-12-14
NL7806381A (nl) 1978-12-15
DK262978A (da) 1978-12-14
CA1077937A (en) 1980-05-20
HU176972B (hu) 1981-06-28
YU140178A (en) 1983-01-21
DE2825861A1 (de) 1979-01-04
CS244653B2 (en) 1986-08-14
DK148683C (da) 1986-02-24
DD138901A5 (de) 1979-11-28
NO154392C (no) 1986-09-10
FR2394535A1 (fr) 1979-01-12
BG33283A3 (en) 1983-01-14
JPS6019754B2 (ja) 1985-05-17
IL54899A0 (en) 1978-08-31
YU40710B (en) 1986-04-30
ES470751A1 (es) 1979-02-01

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