SE441925B - Halogenvinkamonderivat, forfarande for framstellning derav och famaceutisk beredning - Google Patents
Halogenvinkamonderivat, forfarande for framstellning derav och famaceutisk beredningInfo
- Publication number
- SE441925B SE441925B SE8005686A SE8005686A SE441925B SE 441925 B SE441925 B SE 441925B SE 8005686 A SE8005686 A SE 8005686A SE 8005686 A SE8005686 A SE 8005686A SE 441925 B SE441925 B SE 441925B
- Authority
- SE
- Sweden
- Prior art keywords
- acid
- general formula
- acid addition
- addition salt
- derivatives
- Prior art date
Links
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- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 150000003460 sulfonic acids Chemical class 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 230000001839 systemic circulation Effects 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 108010072897 transcription factor Brn-2 Proteins 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 229960002726 vincamine Drugs 0.000 description 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU79RI722A HU180929B (en) | 1979-08-13 | 1979-08-13 | Process for producing new bromo-vincamone derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8005686L SE8005686L (sv) | 1981-02-14 |
| SE441925B true SE441925B (sv) | 1985-11-18 |
Family
ID=11001105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8005686A SE441925B (sv) | 1979-08-13 | 1980-08-12 | Halogenvinkamonderivat, forfarande for framstellning derav och famaceutisk beredning |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4356305A (de) |
| JP (1) | JPS5822154B2 (de) |
| AT (1) | AT374200B (de) |
| AU (1) | AU530761B2 (de) |
| BE (1) | BE884620A (de) |
| CA (1) | CA1152076A (de) |
| CH (1) | CH645643A5 (de) |
| DE (1) | DE3026654A1 (de) |
| DK (1) | DK154083C (de) |
| ES (1) | ES494086A0 (de) |
| FI (1) | FI68623C (de) |
| FR (1) | FR2463139A1 (de) |
| GB (1) | GB2056452B (de) |
| HU (1) | HU180929B (de) |
| IL (1) | IL60588A (de) |
| IT (1) | IT1132403B (de) |
| NL (1) | NL8004348A (de) |
| NO (1) | NO154396C (de) |
| NZ (1) | NZ194653A (de) |
| PH (1) | PH16002A (de) |
| SE (1) | SE441925B (de) |
| ZA (1) | ZA804341B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU187139B (en) * | 1982-06-30 | 1985-11-28 | Richter Gedeon Vegyeszet | Process for preparing new eburnan derivatives |
| LU84664A1 (fr) * | 1983-02-25 | 1984-11-08 | Onmichem S A | Alkyl-4-indolonaphtyridines et leur application therapeutique |
| DE3340025C2 (de) * | 1983-11-03 | 1986-01-09 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur Herstellung von 2-Brom-8-ergolinyl-Verbindungen |
| JP2581570B2 (ja) * | 1987-10-19 | 1997-02-12 | 富士写真フイルム株式会社 | ビデオ用磁気記録媒体 |
| FR2623501B1 (fr) * | 1987-11-19 | 1990-03-16 | Roussel Uclaf | Nouveaux derives substitues de 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
| US5202338A (en) * | 1990-10-31 | 1993-04-13 | Vilmos Bar | Dihydroquinoline derivatives, pharmaceutical compositions and methods of use of dihydroquinoline derivatives as modulators of the arachidonic acid cascade |
| JP3135741B2 (ja) * | 1993-05-07 | 2001-02-19 | 富士写真フイルム株式会社 | 研磨体 |
| US5573444A (en) * | 1993-06-22 | 1996-11-12 | Fuji Photo Film Co., Ltd. | Polishing method |
| US5611826A (en) * | 1994-03-01 | 1997-03-18 | Fuji Photo Film Co., Ltd. | Abrasive tape |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2085630A1 (en) * | 1970-04-07 | 1971-12-31 | Le Men Georges | Vincamone compsn - having vasodilator ganglioplegic and antihistamine activity |
| FR2168853B1 (de) * | 1972-01-24 | 1975-04-25 | Centre Etd Ind Pharma | |
| US3852453A (en) * | 1972-05-26 | 1974-12-03 | Synthelabo | Method of enhancing vincamine compositions |
| FR2206090A1 (en) * | 1972-11-16 | 1974-06-07 | Omnium Chimique Sa | Homovincamone-contg. medicaments - with vasodilating, spasmolytic anti-arrhythmic and anti-ischaemic properties |
| DK139358B (da) * | 1973-12-18 | 1979-02-05 | Sandoz Ag | Analogifremgangsmåde til fremstilling af vincaminderivater eller syreadditionssalte deraf. |
| US4146643A (en) * | 1973-12-18 | 1979-03-27 | Sandoz Ltd. | Increasing vigilance or treating cerebral insufficiency with substituted vincamines |
| DE2538095A1 (de) * | 1974-09-06 | 1976-03-25 | Sandoz Ag | Neue organische verbindungen, ihre herstellung und verwendung |
| FR2339618A1 (fr) * | 1976-01-30 | 1977-08-26 | Omnium Chimique Sa | Procede de preparation de (-)11-aminovincamone, de 11-aminoeburamonine, de 11-aminovincamone racemique et derives indoliques nouveaux |
| DE2703920A1 (de) * | 1976-02-05 | 1977-08-11 | Sandoz Ag | Neue organische verbindungen, ihre herstellung und verwendung |
| FR2398746A1 (fr) * | 1977-07-25 | 1979-02-23 | Roussel Uclaf | Nouveaux derives d'alcaloides pentacycliques, leur procede de preparation, leur application comme medicaments, et leur application a la synthese de produits du groupe de l'eburnamonine |
| FR2407931A1 (fr) * | 1977-11-02 | 1979-06-01 | Synthelabo | Derives de l'eburnamenine et leur application en therapeutique |
| DE2922316A1 (de) * | 1978-06-12 | 1979-12-20 | Omnium Chimique Sa | Neue halogenderivate des vincamins, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| FR2428646A1 (fr) * | 1978-06-12 | 1980-01-11 | Omnium Chimique Sa | Bromo-10-oxo-16-eburnane et bromo-16-14,15-eburnane, procede pour leur preparation et leur application comme medicaments |
| FR2428644A2 (fr) * | 1978-06-12 | 1980-01-11 | Omnium Chimique Sa | Bromo-10-vincamine et bromo-10-14, 15-vincamine, procede pour leur preparation et leur application comme medicaments |
| CH649295A5 (de) * | 1978-07-12 | 1985-05-15 | Richter Gedeon Vegyeszet | Optisch aktive oder razemische brom-e-homo-eburanderivate. |
| US4285949A (en) * | 1978-12-11 | 1981-08-25 | Omnichem Societe Anonyme | Vincamine derivatives, their preparation and therapeutical use |
| HU180928B (en) * | 1979-08-06 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for preparing new brominated 15-hydroxy-e-homo-eburane derivatives |
| HU181496B (en) * | 1979-08-13 | 1983-07-28 | Richter Gedeon Vegyeszet | Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes |
-
1979
- 1979-08-13 HU HU79RI722A patent/HU180929B/hu not_active IP Right Cessation
-
1980
- 1980-07-14 DE DE19803026654 patent/DE3026654A1/de not_active Withdrawn
- 1980-07-15 IL IL60588A patent/IL60588A/xx unknown
- 1980-07-17 ZA ZA00804341A patent/ZA804341B/xx unknown
- 1980-07-24 PH PH24346A patent/PH16002A/en unknown
- 1980-07-30 NL NL8004348A patent/NL8004348A/nl not_active Application Discontinuation
- 1980-07-31 AT AT0396380A patent/AT374200B/de not_active IP Right Cessation
- 1980-08-04 BE BE1/9916A patent/BE884620A/fr not_active IP Right Cessation
- 1980-08-05 US US06/175,384 patent/US4356305A/en not_active Expired - Lifetime
- 1980-08-06 JP JP55107242A patent/JPS5822154B2/ja not_active Expired
- 1980-08-07 FI FI802483A patent/FI68623C/fi not_active IP Right Cessation
- 1980-08-08 ES ES494086A patent/ES494086A0/es active Granted
- 1980-08-11 CH CH605180A patent/CH645643A5/de not_active IP Right Cessation
- 1980-08-11 GB GB8026067A patent/GB2056452B/en not_active Expired
- 1980-08-12 SE SE8005686A patent/SE441925B/sv not_active IP Right Cessation
- 1980-08-12 AU AU61369/80A patent/AU530761B2/en not_active Ceased
- 1980-08-12 DK DK347980A patent/DK154083C/da active
- 1980-08-12 NZ NZ194653A patent/NZ194653A/xx unknown
- 1980-08-12 NO NO802402A patent/NO154396C/no unknown
- 1980-08-12 FR FR8017734A patent/FR2463139A1/fr active Granted
- 1980-08-13 CA CA000358151A patent/CA1152076A/en not_active Expired
- 1980-08-13 IT IT24150/80A patent/IT1132403B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| HU180929B (en) | 1983-05-30 |
| IT8024150A0 (it) | 1980-08-13 |
| ES8106516A1 (es) | 1981-08-01 |
| AU6136980A (en) | 1981-02-19 |
| FI68623B (fi) | 1985-06-28 |
| DK154083B (da) | 1988-10-10 |
| NL8004348A (nl) | 1981-02-17 |
| AT374200B (de) | 1984-03-26 |
| NO154396C (no) | 1986-09-10 |
| PH16002A (en) | 1983-05-20 |
| AU530761B2 (en) | 1983-07-28 |
| NO154396B (no) | 1986-06-02 |
| JPS5822154B2 (ja) | 1983-05-06 |
| ZA804341B (en) | 1981-07-29 |
| FI802483A7 (fi) | 1981-02-14 |
| IL60588A (en) | 1984-05-31 |
| IL60588A0 (en) | 1980-09-16 |
| FI68623C (fi) | 1985-10-10 |
| CA1152076A (en) | 1983-08-16 |
| FR2463139B1 (de) | 1983-08-26 |
| BE884620A (fr) | 1981-02-04 |
| NO802402L (no) | 1981-02-16 |
| US4356305A (en) | 1982-10-26 |
| GB2056452A (en) | 1981-03-18 |
| FR2463139A1 (fr) | 1981-02-20 |
| CH645643A5 (de) | 1984-10-15 |
| IT1132403B (it) | 1986-07-02 |
| ATA396380A (de) | 1983-08-15 |
| DK154083C (da) | 1989-02-27 |
| DE3026654A1 (de) | 1981-04-16 |
| ES494086A0 (es) | 1981-08-01 |
| NZ194653A (en) | 1982-12-21 |
| DK347980A (da) | 1981-02-14 |
| GB2056452B (en) | 1983-10-05 |
| SE8005686L (sv) | 1981-02-14 |
| JPS5626890A (en) | 1981-03-16 |
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Legal Events
| Date | Code | Title | Description |
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| NUG | Patent has lapsed |
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