SE436572B - Forfarande for framstellning av androstadien-17-karbonsyraestrar - Google Patents

Forfarande for framstellning av androstadien-17-karbonsyraestrar

Info

Publication number
SE436572B
SE436572B SE7701999A SE7701999A SE436572B SE 436572 B SE436572 B SE 436572B SE 7701999 A SE7701999 A SE 7701999A SE 7701999 A SE7701999 A SE 7701999A SE 436572 B SE436572 B SE 436572B
Authority
SE
Sweden
Prior art keywords
androstadien
preparing
procedure
acid esters
carbonic acid
Prior art date
Application number
SE7701999A
Other languages
English (en)
Swedish (sv)
Other versions
SE7701999L (sv
Inventor
J Kalvoda
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of SE7701999L publication Critical patent/SE7701999L/xx
Publication of SE436572B publication Critical patent/SE436572B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7701999A 1976-02-24 1977-02-23 Forfarande for framstellning av androstadien-17-karbonsyraestrar SE436572B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH225376A CH628355A5 (de) 1976-02-24 1976-02-24 Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.

Publications (2)

Publication Number Publication Date
SE7701999L SE7701999L (sv) 1977-08-25
SE436572B true SE436572B (sv) 1985-01-07

Family

ID=4229445

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7701999A SE436572B (sv) 1976-02-24 1977-02-23 Forfarande for framstellning av androstadien-17-karbonsyraestrar

Country Status (26)

Country Link
US (1) US4285937A (da)
JP (1) JPS52102264A (da)
AT (1) AT361141B (da)
AU (1) AU513559B2 (da)
BE (1) BE851725A (da)
CA (1) CA1084483A (da)
CH (4) CH628355A5 (da)
CY (1) CY1198A (da)
DD (1) DD145918A5 (da)
DE (1) DE2707336A1 (da)
DK (1) DK153493C (da)
ES (5) ES456134A1 (da)
FR (2) FR2342302A1 (da)
GB (1) GB1578243A (da)
HK (1) HK57483A (da)
HU (1) HU176762B (da)
IE (1) IE45023B1 (da)
IL (2) IL51519A (da)
KE (1) KE3300A (da)
MX (1) MX9203366A (da)
MY (1) MY8500017A (da)
NL (1) NL7701886A (da)
NZ (1) NZ183418A (da)
SE (1) SE436572B (da)
SG (1) SG37383G (da)
ZA (1) ZA771087B (da)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0197018A1 (en) * 1985-04-04 1986-10-08 Aktiebolaget Draco 16,17-Acetal-substituted androstane-17-beta-carboxylic-acid esters, process for their preparation and pharmaceutical compound containing them
EP0200692A1 (en) * 1985-04-04 1986-11-05 Aktiebolaget Draco Androstane-17-beta-carboxylic-acid esters, process for their preparation and pharmaceutical compound containing them

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT7967677A0 (it) * 1978-04-05 1979-03-30 Syntex Inc Erivati dell acido 4 alogeno etiani co ad azione antinfiammatoria e procedimento per la loro preparazione
US4198403A (en) * 1978-04-05 1980-04-15 Syntex (U.S.A.) Inc. 17 Beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes
US4188385A (en) * 1978-04-05 1980-02-12 Syntex (U.S.A.) Inc. Thioetianic acid derivatives
DE3024008C2 (de) * 1980-06-24 1982-04-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 17α-Hydroxy-etiocarbonsäuren
US4607028A (en) * 1983-08-18 1986-08-19 Ciba-Geigy Corporation Novel carboxylic acid esters
SE8306370D0 (sv) * 1983-11-18 1983-11-18 Draco Ab Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
WO1990015816A1 (en) * 1989-06-16 1990-12-27 The Upjohn Company Suramin type compounds and angiostatic steroids to inhibit angiogenesis
US6596260B1 (en) 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
US5646136A (en) * 1994-01-04 1997-07-08 Duke University Methods of inhibiting angiogenesis and tumor growth, and treating ophthalmologic conditions with angiostatic and therapeutic steroids
US5981517A (en) * 1996-05-09 1999-11-09 Soft Drugs, Inc. Androstene derivatives
GB0015876D0 (en) * 2000-06-28 2000-08-23 Novartis Ag Organic compounds
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6750210B2 (en) * 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
ES2292604T5 (es) * 2000-08-05 2015-06-01 Glaxo Group Limited Éster S-fluorometílico del ácido 6 ,9 -difluoro-17 -[(2-furanilcarbonil)oxi]-11 -hidroxi-16 -metil-3-oxo-androsta-1,4-dien-17 -carbotioico como agente antiinflamatorio
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6787532B2 (en) * 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6777400B2 (en) * 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6858593B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
UA77656C2 (en) * 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
CN1302007C (zh) * 2001-04-30 2007-02-28 葛兰素集团有限公司 具有抗炎性的在17.α位上具有环酯基的雄甾烷的17.β.－硫代羧酸酯衍生物
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
DE602004025002D1 (de) * 2003-06-19 2010-02-25 Nicholas S Bodor Steigerung der aktivität und/oder der wirkungsdauer weicher steroide mit anti-entzündungswirkung für topische oder lokale verabreichung
DE602004008083T2 (de) * 2003-06-19 2008-04-24 Nicholas S. Gainsville Bodor Verstärkung der aktivität und/oder wirkdauer von ausgewählten entzündungshemmenden steroiden
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
EP1948167A1 (en) * 2005-10-19 2008-07-30 Ranbaxy Laboratories, Ltd. Compositions of phosphodiesterase type iv inhibitors
US7691811B2 (en) * 2006-05-25 2010-04-06 Bodor Nicholas S Transporter-enhanced corticosteroid activity and methods and compositions for treating dry eye
US7687484B2 (en) * 2006-05-25 2010-03-30 Bodor Nicholas S Transporter enhanced corticosteroid activity
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
US8227027B2 (en) 2007-12-07 2012-07-24 Presspart Gmbh & Co. Kg Method for applying a polymer coating to an internal surface of a container
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
US8835410B2 (en) 2011-05-10 2014-09-16 Bodor Laboratories, Inc. Treatment of eyelid dermatitis
CN111100176A (zh) * 2019-12-20 2020-05-05 重庆华邦胜凯制药有限公司 一种化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636010A (en) * 1968-12-23 1972-01-18 Ciba Geigy Corp Esters of steroid-17-carboxylic acids
GB1384372A (en) * 1971-01-20 1975-02-19 Glaxo Lab Ltd Dereivatives of 17alpha-hydroxyandrost-4-ene-17beta-carboxylic acids
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
US4093721A (en) * 1974-08-30 1978-06-06 Glaxo Laboratories Limited Pharmaceutical compositions of 6α,9α-difluoro-androst-4-ene-17β-carboxylates and derivatives thereof
GB1514476A (en) * 1974-08-30 1978-06-14 Glaxo Lab Ltd Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0197018A1 (en) * 1985-04-04 1986-10-08 Aktiebolaget Draco 16,17-Acetal-substituted androstane-17-beta-carboxylic-acid esters, process for their preparation and pharmaceutical compound containing them
EP0200692A1 (en) * 1985-04-04 1986-11-05 Aktiebolaget Draco Androstane-17-beta-carboxylic-acid esters, process for their preparation and pharmaceutical compound containing them
EP0355859A1 (en) * 1985-04-04 1990-02-28 Aktiebolaget Draco Process for the preparation of intermediates for 11-beta,16-alpha,17-alpha,21-tetrahydroxypregna-3,20-dione 16-alpha,17-alpha-acetals and 21-esters thereof
US4950659A (en) * 1985-04-04 1990-08-21 Aktiebolaget Draco 16,17-acetalsubstituted androstane-17β-carboxylic acid esters prossessing high binding affinity to the glucocorticosteroid receptor

Also Published As

Publication number Publication date
CY1198A (en) 1983-12-31
DK153493B (da) 1988-07-18
FR2369297B1 (da) 1981-03-06
DE2707336A1 (de) 1977-08-25
IL51519A0 (en) 1977-04-29
ZA771087B (en) 1978-01-25
NL7701886A (nl) 1977-08-26
SG37383G (en) 1984-02-17
IL61512A0 (en) 1980-12-31
GB1578243A (en) 1980-11-05
FR2342302B1 (da) 1981-01-09
CH628356A5 (de) 1982-02-26
AU2257277A (en) 1978-08-31
US4285937A (en) 1981-08-25
FR2342302A1 (fr) 1977-09-23
MY8500017A (en) 1985-12-31
IE45023L (en) 1977-08-24
ES467430A1 (es) 1979-08-16
JPS6139959B2 (da) 1986-09-06
BE851725A (fr) 1977-08-23
DE2707336C2 (da) 1988-09-01
CH629824A5 (de) 1982-05-14
ATA119477A (de) 1980-07-15
AT361141B (de) 1981-02-25
DD145918A5 (de) 1981-01-14
HU176762B (en) 1981-05-28
DK79077A (da) 1977-08-25
NZ183418A (en) 1980-02-21
CH628355A5 (de) 1982-02-26
IE45023B1 (en) 1982-06-02
FR2369297A1 (fr) 1978-05-26
CA1084483A (en) 1980-08-26
ES467434A1 (es) 1979-08-16
ES467432A1 (es) 1979-08-16
KE3300A (en) 1983-08-05
DK153493C (da) 1988-11-28
ES456134A1 (es) 1978-05-01
JPS52102264A (en) 1977-08-27
CH628641A5 (de) 1982-03-15
AU513559B2 (en) 1980-12-11
MX9203366A (es) 1992-09-01
IL51519A (en) 1983-03-31
SE7701999L (sv) 1977-08-25
HK57483A (en) 1983-11-25
ES467433A1 (es) 1979-10-16

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