SE429339B - 3-indonyl-tert.butylaminopropanoler med terapeutiska egenskaper - Google Patents

3-indonyl-tert.butylaminopropanoler med terapeutiska egenskaper

Info

Publication number
SE429339B
SE429339B SE7807700A SE7807700A SE429339B SE 429339 B SE429339 B SE 429339B SE 7807700 A SE7807700 A SE 7807700A SE 7807700 A SE7807700 A SE 7807700A SE 429339 B SE429339 B SE 429339B
Authority
SE
Sweden
Prior art keywords
formula
phenyl
compounds
alkyl
agents
Prior art date
Application number
SE7807700A
Other languages
English (en)
Swedish (sv)
Other versions
SE7807700L (sv
Inventor
W E Kreighbaum
W T Comer
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of SE7807700L publication Critical patent/SE7807700L/xx
Publication of SE429339B publication Critical patent/SE429339B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SE7807700A 1977-07-13 1978-07-10 3-indonyl-tert.butylaminopropanoler med terapeutiska egenskaper SE429339B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81513877A 1977-07-13 1977-07-13

Publications (2)

Publication Number Publication Date
SE7807700L SE7807700L (sv) 1979-01-14
SE429339B true SE429339B (sv) 1983-08-29

Family

ID=25216976

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7807700A SE429339B (sv) 1977-07-13 1978-07-10 3-indonyl-tert.butylaminopropanoler med terapeutiska egenskaper

Country Status (30)

Country Link
JP (1) JPS5419972A (zh)
AR (1) AR225274A1 (zh)
AT (1) AT364821B (zh)
AU (1) AU525064B2 (zh)
BE (1) BE868943A (zh)
CA (1) CA1116598A (zh)
CH (1) CH642066A5 (zh)
CY (1) CY1274A (zh)
DE (1) DE2830884A1 (zh)
DK (1) DK156568C (zh)
ES (1) ES471674A1 (zh)
FI (1) FI69835C (zh)
FR (1) FR2397404A1 (zh)
GB (1) GB2001633B (zh)
GR (1) GR74488B (zh)
HK (1) HK1385A (zh)
HU (1) HU178992B (zh)
IE (1) IE47122B1 (zh)
IL (1) IL55115A (zh)
IT (1) IT1105091B (zh)
KE (1) KE3485A (zh)
LU (1) LU79966A1 (zh)
MY (1) MY8500946A (zh)
NL (1) NL189946C (zh)
NO (1) NO149311C (zh)
NZ (1) NZ187763A (zh)
SE (1) SE429339B (zh)
SG (1) SG82584G (zh)
YU (1) YU40528B (zh)
ZA (1) ZA783744B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
US4321398A (en) * 1981-05-07 1982-03-23 Mead Johnson & Company Thienyl and benzothienyl-tertiary butylaminophenoxypropanols
DE3119796A1 (de) * 1981-05-19 1982-12-23 Hoechst Ag, 6000 Frankfurt Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung
FR2523964B1 (fr) * 1982-03-23 1985-09-27 Sanofi Sa Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation
NZ208337A (en) * 1983-06-10 1988-10-28 Bristol Myers Co 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
US6825220B2 (en) 2000-11-10 2004-11-30 Eli Lilly And Company 3-Substituted oxindole β 3 agonists
WO2003016307A1 (en) * 2001-08-14 2003-02-27 Eli Lilly And Company β3 ADRENERGIC AGONISTS
DE60211199T2 (de) 2001-08-14 2007-02-01 Eli Lilly And Co., Indianapolis 3-substituierte oxindol-beta-3-agonisten
JP2005518357A (ja) 2001-11-20 2005-06-23 イーライ・リリー・アンド・カンパニー ベータ３アドレナリンアゴニスト
JP2005514366A (ja) 2001-11-20 2005-05-19 イーライ・リリー・アンド・カンパニー ３−置換オキシインドールβ３アゴニスト
EP1467733A1 (en) 2002-01-11 2004-10-20 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as beta3 agonists
CA2732513C (en) 2008-08-01 2017-04-25 Arca Biopharma, Inc. Methods and compositions involving (s)-bucindolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1532210A (fr) * 1963-06-21 1968-07-12 Ici Ltd Composés hétérocycliques et leur procédé de préparation
CH495983A (de) * 1968-02-09 1970-09-15 Sandoz Ag Verfahren zur Herstellung von linksdrehendem 4-(2-Hydroxy-3-isopropylaminopropoxy)indol
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines

Also Published As

Publication number Publication date
YU161178A (en) 1983-02-28
IT1105091B (it) 1985-10-28
ES471674A1 (es) 1979-10-01
DE2830884C2 (zh) 1990-01-11
IE781400L (en) 1979-01-13
JPS5419972A (en) 1979-02-15
IT7850228A0 (it) 1978-07-10
NL189946B (nl) 1993-04-16
SG82584G (en) 1985-09-13
KE3485A (en) 1985-01-25
DK313878A (da) 1979-01-14
AU525064B2 (en) 1982-10-21
GB2001633B (en) 1982-03-24
NL7807564A (nl) 1979-01-16
FR2397404B1 (zh) 1982-06-11
IL55115A (en) 1981-09-13
DK156568C (da) 1990-02-05
ATA508978A (de) 1981-04-15
AT364821B (de) 1981-11-25
AR225274A1 (es) 1982-03-15
DE2830884A1 (de) 1979-02-01
AU3770478A (en) 1980-01-10
NL189946C (nl) 1993-09-16
GR74488B (zh) 1984-06-28
ZA783744B (en) 1979-07-25
NZ187763A (en) 1984-07-31
YU40528B (en) 1986-02-28
FI782205A (fi) 1979-01-14
HU178992B (en) 1982-07-28
FR2397404A1 (fr) 1979-02-09
GB2001633A (en) 1979-02-07
SE7807700L (sv) 1979-01-14
NO149311B (no) 1983-12-19
NO782407L (no) 1979-01-16
IL55115A0 (en) 1978-09-29
JPS6340784B2 (zh) 1988-08-12
FI69835B (fi) 1985-12-31
MY8500946A (en) 1985-12-31
CH642066A5 (de) 1984-03-30
HK1385A (en) 1985-01-11
CY1274A (en) 1985-03-08
IE47122B1 (en) 1983-12-28
LU79966A1 (fr) 1979-04-09
CA1116598A (en) 1982-01-19
FI69835C (fi) 1986-05-26
NO149311C (no) 1984-03-28
DK156568B (da) 1989-09-11
BE868943A (fr) 1979-01-12

Similar Documents

Publication Publication Date Title
US4234595A (en) 3-Indolyl-tertiary butylaminopropanols
CS244423B2 (en) Method of substituted 1,2-diaminocyclobuten-3,4-dions production
JPS62230722A (ja) 肥満および／または関連状態の治療剤
SE429339B (sv) 3-indonyl-tert.butylaminopropanoler med terapeutiska egenskaper
WO1999062892A1 (en) Aminoazole compounds
JPS6230780A (ja) １，７−ナフチリジン誘導体及びこれを含有する薬剤
HU212302B (en) Process for producing imidazole guanidine derivatives and pharmaceutical compositions containing them
WO1998027982A1 (fr) Composition contenant de l'acide ascorbique
JP2002533332A (ja) 治療活性化合物としてのスルホニルオキサゾールアミン成分
RU2056416C1 (ru) Производные тиомочевины, фармацевтическая композиция и способ лечения
JPS6323191B2 (zh)
CZ263692A3 (en) Thiadiazinones, process of their preparation and pharmaceutical compositions based thereon
NZ204072A (en) Pharmaceutical compositions which contain theophylline as active ingredient
US4772704A (en) 2,5-disubstituted-4(3H)-pyrimidones having histamine H2 -receptor antagonist activity
KR820001447B1 (ko) 3-인돌릴-3급 부틸아미노프로판올의 제조방법
US3997667A (en) 1-[3-(Naphth-1-yloxy)-propyl]-piperazine compounds and therapeutic compositions
EP0260814B1 (en) Dopamine-beta-hydroxylase inhibitors
US4153696A (en) Dihydroxyphenylethylaminoalkyl theophyllines
JPH0262554B2 (zh)
JPS59141565A (ja) 向精神性活性を有するピリダジン誘導体，その製造方法および該誘導体を含有する薬剤
RU2045521C1 (ru) Производные 1,2,4-триазолилтиоамидов
US3485924A (en) Pharmaceutical compositions and methods for reducing appetite in animals
CS247196B2 (en) Method of new substituted isochromates and oxopines production
CN116535361A (zh) 取代羟基嘧啶类黄嘌呤氧化酶抑制剂及其制法和药物用途
JPH01216980A (ja) アルキル―ピペラジニル―５，６―アルキレンピリミジン類

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7807700-5

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7807700-5

Format of ref document f/p: F