NL7807564A - 3-indolyl-tertiaire butylaminopropanolen. - Google Patents

3-indolyl-tertiaire butylaminopropanolen.

Info

Publication number
NL7807564A
NL7807564A NL7807564A NL7807564A NL7807564A NL 7807564 A NL7807564 A NL 7807564A NL 7807564 A NL7807564 A NL 7807564A NL 7807564 A NL7807564 A NL 7807564A NL 7807564 A NL7807564 A NL 7807564A
Authority
NL
Netherlands
Prior art keywords
butylaminopropanols
indolyl
tertiary
tertiary butylaminopropanols
Prior art date
Application number
NL7807564A
Other languages
English (en)
Other versions
NL189946C (nl
NL189946B (nl
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of NL7807564A publication Critical patent/NL7807564A/nl
Publication of NL189946B publication Critical patent/NL189946B/nl
Application granted granted Critical
Publication of NL189946C publication Critical patent/NL189946C/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
NLAANVRAGE7807564,A 1977-07-13 1978-07-13 1-aryloxy-3-(indool-3-yl)alkylamino-2-propanolverbinding met een anti-hypertensieve, beta-adrenergisch blokkerende en vaatverwijdende werking, alsmede werkwijze ter bereiding van een farmaceutisch preparaat. NL189946C (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81513877A 1977-07-13 1977-07-13

Publications (3)

Publication Number Publication Date
NL7807564A true NL7807564A (nl) 1979-01-16
NL189946B NL189946B (nl) 1993-04-16
NL189946C NL189946C (nl) 1993-09-16

Family

ID=25216976

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7807564,A NL189946C (nl) 1977-07-13 1978-07-13 1-aryloxy-3-(indool-3-yl)alkylamino-2-propanolverbinding met een anti-hypertensieve, beta-adrenergisch blokkerende en vaatverwijdende werking, alsmede werkwijze ter bereiding van een farmaceutisch preparaat.

Country Status (30)

Country Link
JP (1) JPS5419972A (nl)
AR (1) AR225274A1 (nl)
AT (1) AT364821B (nl)
AU (1) AU525064B2 (nl)
BE (1) BE868943A (nl)
CA (1) CA1116598A (nl)
CH (1) CH642066A5 (nl)
CY (1) CY1274A (nl)
DE (1) DE2830884A1 (nl)
DK (1) DK156568C (nl)
ES (1) ES471674A1 (nl)
FI (1) FI69835C (nl)
FR (1) FR2397404A1 (nl)
GB (1) GB2001633B (nl)
GR (1) GR74488B (nl)
HK (1) HK1385A (nl)
HU (1) HU178992B (nl)
IE (1) IE47122B1 (nl)
IL (1) IL55115A (nl)
IT (1) IT1105091B (nl)
KE (1) KE3485A (nl)
LU (1) LU79966A1 (nl)
MY (1) MY8500946A (nl)
NL (1) NL189946C (nl)
NO (1) NO149311C (nl)
NZ (1) NZ187763A (nl)
SE (1) SE429339B (nl)
SG (1) SG82584G (nl)
YU (1) YU40528B (nl)
ZA (1) ZA783744B (nl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
US4321398A (en) * 1981-05-07 1982-03-23 Mead Johnson & Company Thienyl and benzothienyl-tertiary butylaminophenoxypropanols
DE3119796A1 (de) * 1981-05-19 1982-12-23 Hoechst Ag, 6000 Frankfurt Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung
FR2523964B1 (fr) * 1982-03-23 1985-09-27 Sanofi Sa Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation
NZ208337A (en) * 1983-06-10 1988-10-28 Bristol Myers Co 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
CA2421594A1 (en) 2000-11-10 2002-05-16 John Arnold Werner 3-substituted oxindole beta 3 agonists
DE60211199T2 (de) 2001-08-14 2007-02-01 Eli Lilly And Co., Indianapolis 3-substituierte oxindol-beta-3-agonisten
ES2272749T3 (es) * 2001-08-14 2007-05-01 Eli Lilly And Company Derivados de indol como agonistas beta-3 adrenergicos para el tratamiento de diabetes tipo 2.
JP2005518357A (ja) 2001-11-20 2005-06-23 イーライ・リリー・アンド・カンパニー ベータ３アドレナリンアゴニスト
ATE297925T1 (de) 2001-11-20 2005-07-15 Lilly Co Eli 3-substituierte oxindol beta 3 agonisten
US7009060B2 (en) 2002-01-11 2006-03-07 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as β3 agonists
CA2960254A1 (en) 2008-08-01 2010-02-04 Arca Biopharma, Inc. Methods and compositions involving (s)-bucindolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1532210A (fr) * 1963-06-21 1968-07-12 Ici Ltd Composés hétérocycliques et leur procédé de préparation
CH495983A (de) * 1968-02-09 1970-09-15 Sandoz Ag Verfahren zur Herstellung von linksdrehendem 4-(2-Hydroxy-3-isopropylaminopropoxy)indol
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines

Also Published As

Publication number Publication date
DK156568B (da) 1989-09-11
ZA783744B (en) 1979-07-25
FR2397404A1 (fr) 1979-02-09
GB2001633A (en) 1979-02-07
GR74488B (nl) 1984-06-28
NO782407L (no) 1979-01-16
FR2397404B1 (nl) 1982-06-11
NL189946C (nl) 1993-09-16
CY1274A (en) 1985-03-08
SE7807700L (sv) 1979-01-14
IT1105091B (it) 1985-10-28
YU161178A (en) 1983-02-28
YU40528B (en) 1986-02-28
MY8500946A (en) 1985-12-31
ATA508978A (de) 1981-04-15
IE781400L (en) 1979-01-13
LU79966A1 (fr) 1979-04-09
CA1116598A (en) 1982-01-19
IT7850228A0 (it) 1978-07-10
AT364821B (de) 1981-11-25
NL189946B (nl) 1993-04-16
SG82584G (en) 1985-09-13
SE429339B (sv) 1983-08-29
BE868943A (fr) 1979-01-12
ES471674A1 (es) 1979-10-01
DK313878A (da) 1979-01-14
JPS5419972A (en) 1979-02-15
GB2001633B (en) 1982-03-24
AU3770478A (en) 1980-01-10
IL55115A0 (en) 1978-09-29
AR225274A1 (es) 1982-03-15
DE2830884C2 (nl) 1990-01-11
CH642066A5 (de) 1984-03-30
NO149311C (no) 1984-03-28
DE2830884A1 (de) 1979-02-01
FI69835B (fi) 1985-12-31
HK1385A (en) 1985-01-11
JPS6340784B2 (nl) 1988-08-12
FI782205A (fi) 1979-01-14
KE3485A (en) 1985-01-25
AU525064B2 (en) 1982-10-21
IL55115A (en) 1981-09-13
NO149311B (no) 1983-12-19
IE47122B1 (en) 1983-12-28
DK156568C (da) 1990-02-05
FI69835C (fi) 1986-05-26
NZ187763A (en) 1984-07-31
HU178992B (en) 1982-07-28

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
DNT Communications of changes of names of applicants whose applications have been laid open to public inspection

Free format text: BRISTOL-MYERS SQUIBB COMPANY

V4 Discontinued because of reaching the maximum lifetime of a patent

Free format text: 980713