DK156568C - Analogifremgangsmaade til fremstilling af 3-indolderivater - Google Patents

Analogifremgangsmaade til fremstilling af 3-indolderivater

Info

Publication number
DK156568C
DK156568C DK313878A DK313878A DK156568C DK 156568 C DK156568 C DK 156568C DK 313878 A DK313878 A DK 313878A DK 313878 A DK313878 A DK 313878A DK 156568 C DK156568 C DK 156568C
Authority
DK
Denmark
Prior art keywords
preparation
analogy procedure
derivatives
content
content derivatives
Prior art date
Application number
DK313878A
Other languages
Danish (da)
English (en)
Other versions
DK313878A (da
DK156568B (da
Inventor
William E Kreighbaum
William T Comer
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DK313878A publication Critical patent/DK313878A/da
Publication of DK156568B publication Critical patent/DK156568B/da
Application granted granted Critical
Publication of DK156568C publication Critical patent/DK156568C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK313878A 1977-07-13 1978-07-12 Analogifremgangsmaade til fremstilling af 3-indolderivater DK156568C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81513877A 1977-07-13 1977-07-13
US81513877 1977-07-13

Publications (3)

Publication Number Publication Date
DK313878A DK313878A (da) 1979-01-14
DK156568B DK156568B (da) 1989-09-11
DK156568C true DK156568C (da) 1990-02-05

Family

ID=25216976

Family Applications (1)

Application Number Title Priority Date Filing Date
DK313878A DK156568C (da) 1977-07-13 1978-07-12 Analogifremgangsmaade til fremstilling af 3-indolderivater

Country Status (30)

Country Link
JP (1) JPS5419972A (nl)
AR (1) AR225274A1 (nl)
AT (1) AT364821B (nl)
AU (1) AU525064B2 (nl)
BE (1) BE868943A (nl)
CA (1) CA1116598A (nl)
CH (1) CH642066A5 (nl)
CY (1) CY1274A (nl)
DE (1) DE2830884A1 (nl)
DK (1) DK156568C (nl)
ES (1) ES471674A1 (nl)
FI (1) FI69835C (nl)
FR (1) FR2397404A1 (nl)
GB (1) GB2001633B (nl)
GR (1) GR74488B (nl)
HK (1) HK1385A (nl)
HU (1) HU178992B (nl)
IE (1) IE47122B1 (nl)
IL (1) IL55115A (nl)
IT (1) IT1105091B (nl)
KE (1) KE3485A (nl)
LU (1) LU79966A1 (nl)
MY (1) MY8500946A (nl)
NL (1) NL189946C (nl)
NO (1) NO149311C (nl)
NZ (1) NZ187763A (nl)
SE (1) SE429339B (nl)
SG (1) SG82584G (nl)
YU (1) YU40528B (nl)
ZA (1) ZA783744B (nl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
US4321398A (en) * 1981-05-07 1982-03-23 Mead Johnson & Company Thienyl and benzothienyl-tertiary butylaminophenoxypropanols
DE3119796A1 (de) * 1981-05-19 1982-12-23 Hoechst Ag, 6000 Frankfurt Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung
FR2523964B1 (fr) * 1982-03-23 1985-09-27 Sanofi Sa Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation
NZ208337A (en) * 1983-06-10 1988-10-28 Bristol Myers Co 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
JP2004513164A (ja) 2000-11-10 2004-04-30 イーライ・リリー・アンド・カンパニー 3−置換オキシインドールβ3アゴニスト
EP1444224B1 (en) 2001-08-14 2006-05-03 Eli Lilly And Company 3-substituted oxindole beta-3 agonists
ATE340794T1 (de) * 2001-08-14 2006-10-15 Lilly Co Eli Indol derivate als beta-3-adrenerge agonisten zur behandlung von typ 2 diabetes
DE60225174T2 (de) 2001-11-20 2009-02-12 Eli Lilly And Co., Indianapolis Beta-3 adrenergische agonisten
US7205407B2 (en) 2001-11-20 2007-04-17 Eli Lilly And Company 3-Substituted oxindole β3 agonists
EP1467733A1 (en) 2002-01-11 2004-10-20 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as beta3 agonists
CA2960254A1 (en) 2008-08-01 2010-02-04 Arca Biopharma, Inc. Methods and compositions involving (s)-bucindolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1532210A (fr) * 1963-06-21 1968-07-12 Ici Ltd Composés hétérocycliques et leur procédé de préparation
CH495983A (de) * 1968-02-09 1970-09-15 Sandoz Ag Verfahren zur Herstellung von linksdrehendem 4-(2-Hydroxy-3-isopropylaminopropoxy)indol
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines

Also Published As

Publication number Publication date
IT1105091B (it) 1985-10-28
HK1385A (en) 1985-01-11
ATA508978A (de) 1981-04-15
NO149311C (no) 1984-03-28
FI69835B (fi) 1985-12-31
SE7807700L (sv) 1979-01-14
FR2397404A1 (fr) 1979-02-09
IT7850228A0 (it) 1978-07-10
GB2001633A (en) 1979-02-07
NL189946B (nl) 1993-04-16
JPS5419972A (en) 1979-02-15
DE2830884A1 (de) 1979-02-01
FI782205A (fi) 1979-01-14
CA1116598A (en) 1982-01-19
JPS6340784B2 (nl) 1988-08-12
ZA783744B (en) 1979-07-25
CY1274A (en) 1985-03-08
IE781400L (en) 1979-01-13
IL55115A0 (en) 1978-09-29
FI69835C (fi) 1986-05-26
HU178992B (en) 1982-07-28
GR74488B (nl) 1984-06-28
ES471674A1 (es) 1979-10-01
NZ187763A (en) 1984-07-31
SG82584G (en) 1985-09-13
DE2830884C2 (nl) 1990-01-11
AU3770478A (en) 1980-01-10
FR2397404B1 (nl) 1982-06-11
GB2001633B (en) 1982-03-24
AT364821B (de) 1981-11-25
AR225274A1 (es) 1982-03-15
CH642066A5 (de) 1984-03-30
DK313878A (da) 1979-01-14
NL7807564A (nl) 1979-01-16
NL189946C (nl) 1993-09-16
IL55115A (en) 1981-09-13
YU161178A (en) 1983-02-28
DK156568B (da) 1989-09-11
BE868943A (fr) 1979-01-12
SE429339B (sv) 1983-08-29
LU79966A1 (fr) 1979-04-09
MY8500946A (en) 1985-12-31
IE47122B1 (en) 1983-12-28
YU40528B (en) 1986-02-28
NO782407L (no) 1979-01-16
NO149311B (no) 1983-12-19
AU525064B2 (en) 1982-10-21
KE3485A (en) 1985-01-25

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PUP Patent expired