AT364821B - Verfahren zur herstellung neuer indole, deren saeureadditionssalze und deren isomere - Google Patents
Verfahren zur herstellung neuer indole, deren saeureadditionssalze und deren isomereInfo
- Publication number
- AT364821B AT364821B AT0508978A AT508978A AT364821B AT 364821 B AT364821 B AT 364821B AT 0508978 A AT0508978 A AT 0508978A AT 508978 A AT508978 A AT 508978A AT 364821 B AT364821 B AT 364821B
- Authority
- AT
- Austria
- Prior art keywords
- isomers
- acid addition
- addition salts
- producing new
- new indoles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81513877A | 1977-07-13 | 1977-07-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA508978A ATA508978A (de) | 1981-04-15 |
| AT364821B true AT364821B (de) | 1981-11-25 |
Family
ID=25216976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0508978A AT364821B (de) | 1977-07-13 | 1978-07-13 | Verfahren zur herstellung neuer indole, deren saeureadditionssalze und deren isomere |
Country Status (30)
| Country | Link |
|---|---|
| JP (1) | JPS5419972A (zh) |
| AR (1) | AR225274A1 (zh) |
| AT (1) | AT364821B (zh) |
| AU (1) | AU525064B2 (zh) |
| BE (1) | BE868943A (zh) |
| CA (1) | CA1116598A (zh) |
| CH (1) | CH642066A5 (zh) |
| CY (1) | CY1274A (zh) |
| DE (1) | DE2830884A1 (zh) |
| DK (1) | DK156568C (zh) |
| ES (1) | ES471674A1 (zh) |
| FI (1) | FI69835C (zh) |
| FR (1) | FR2397404A1 (zh) |
| GB (1) | GB2001633B (zh) |
| GR (1) | GR74488B (zh) |
| HK (1) | HK1385A (zh) |
| HU (1) | HU178992B (zh) |
| IE (1) | IE47122B1 (zh) |
| IL (1) | IL55115A (zh) |
| IT (1) | IT1105091B (zh) |
| KE (1) | KE3485A (zh) |
| LU (1) | LU79966A1 (zh) |
| MY (1) | MY8500946A (zh) |
| NL (1) | NL189946C (zh) |
| NO (1) | NO149311C (zh) |
| NZ (1) | NZ187763A (zh) |
| SE (1) | SE429339B (zh) |
| SG (1) | SG82584G (zh) |
| YU (1) | YU40528B (zh) |
| ZA (1) | ZA783744B (zh) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2463765A1 (fr) * | 1979-08-17 | 1981-02-27 | Clin Midy | Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire |
| US4321398A (en) * | 1981-05-07 | 1982-03-23 | Mead Johnson & Company | Thienyl and benzothienyl-tertiary butylaminophenoxypropanols |
| DE3119796A1 (de) * | 1981-05-19 | 1982-12-23 | Hoechst Ag, 6000 Frankfurt | Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung |
| FR2523964B1 (fr) * | 1982-03-23 | 1985-09-27 | Sanofi Sa | Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation |
| NZ208337A (en) * | 1983-06-10 | 1988-10-28 | Bristol Myers Co | 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions |
| FR2601008B1 (fr) * | 1986-07-03 | 1990-03-30 | Sanofi Sa | Procede de synthese stereospecifique de derives de l'indole |
| US6825220B2 (en) | 2000-11-10 | 2004-11-30 | Eli Lilly And Company | 3-Substituted oxindole β 3 agonists |
| WO2003016307A1 (en) * | 2001-08-14 | 2003-02-27 | Eli Lilly And Company | β3 ADRENERGIC AGONISTS |
| DE60211199T2 (de) | 2001-08-14 | 2007-02-01 | Eli Lilly And Co., Indianapolis | 3-substituierte oxindol-beta-3-agonisten |
| JP2005518357A (ja) | 2001-11-20 | 2005-06-23 | イーライ・リリー・アンド・カンパニー | ベータ３アドレナリンアゴニスト |
| JP2005514366A (ja) | 2001-11-20 | 2005-05-19 | イーライ・リリー・アンド・カンパニー | ３−置換オキシインドールβ３アゴニスト |
| EP1467733A1 (en) | 2002-01-11 | 2004-10-20 | Eli Lilly And Company | 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as beta3 agonists |
| CA2732513C (en) | 2008-08-01 | 2017-04-25 | Arca Biopharma, Inc. | Methods and compositions involving (s)-bucindolol |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1532210A (fr) * | 1963-06-21 | 1968-07-12 | Ici Ltd | Composés hétérocycliques et leur procédé de préparation |
| CH495983A (de) * | 1968-02-09 | 1970-09-15 | Sandoz Ag | Verfahren zur Herstellung von linksdrehendem 4-(2-Hydroxy-3-isopropylaminopropoxy)indol |
| US3371098A (en) * | 1966-11-29 | 1968-02-27 | Philips Corp | 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles |
| US3946009A (en) * | 1972-05-05 | 1976-03-23 | Merck Sharp & Dohme (I.A.) Corporation | 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines |
-
1978
- 1978-06-12 CA CA000305281A patent/CA1116598A/en not_active Expired
- 1978-06-29 ZA ZA00783744A patent/ZA783744B/xx unknown
- 1978-07-03 NZ NZ187763A patent/NZ187763A/en unknown
- 1978-07-03 AU AU37704/78A patent/AU525064B2/en not_active Expired
- 1978-07-05 YU YU1611/78A patent/YU40528B/xx unknown
- 1978-07-07 AR AR272873A patent/AR225274A1/es active
- 1978-07-10 SE SE7807700A patent/SE429339B/sv not_active IP Right Cessation
- 1978-07-10 GB GB787829333A patent/GB2001633B/en not_active Expired
- 1978-07-10 IL IL55115A patent/IL55115A/en unknown
- 1978-07-10 IT IT50228/78A patent/IT1105091B/it active
- 1978-07-10 CY CY1274A patent/CY1274A/xx unknown
- 1978-07-10 FI FI782205A patent/FI69835C/fi not_active IP Right Cessation
- 1978-07-11 GR GR56751A patent/GR74488B/el unknown
- 1978-07-11 NO NO782407A patent/NO149311C/no unknown
- 1978-07-12 IE IE1400/78A patent/IE47122B1/en not_active IP Right Cessation
- 1978-07-12 BE BE189237A patent/BE868943A/xx not_active IP Right Cessation
- 1978-07-12 LU LU79966A patent/LU79966A1/xx unknown
- 1978-07-12 FR FR7820851A patent/FR2397404A1/fr active Granted
- 1978-07-12 ES ES471674A patent/ES471674A1/es not_active Expired
- 1978-07-12 CH CH759378A patent/CH642066A5/de not_active IP Right Cessation
- 1978-07-12 DK DK313878A patent/DK156568C/da not_active IP Right Cessation
- 1978-07-12 HU HU78BI569A patent/HU178992B/hu unknown
- 1978-07-13 NL NLAANVRAGE7807564,A patent/NL189946C/xx not_active IP Right Cessation
- 1978-07-13 DE DE19782830884 patent/DE2830884A1/de active Granted
- 1978-07-13 JP JP8461378A patent/JPS5419972A/ja active Granted
- 1978-07-13 AT AT0508978A patent/AT364821B/de not_active IP Right Cessation
-
1984
- 1984-11-19 SG SG825/84A patent/SG82584G/en unknown
- 1984-12-07 KE KE3485A patent/KE3485A/xx unknown
-
1985
- 1985-01-03 HK HK13/85A patent/HK1385A/xx not_active IP Right Cessation
- 1985-12-30 MY MY946/85A patent/MY8500946A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELA | Expired due to lapse of time |