AU525064B2 - 3-indolyl-tertiary butylaminopropanole - Google Patents

3-indolyl-tertiary butylaminopropanole

Info

Publication number
AU525064B2
AU525064B2 AU37704/78A AU3770478A AU525064B2 AU 525064 B2 AU525064 B2 AU 525064B2 AU 37704/78 A AU37704/78 A AU 37704/78A AU 3770478 A AU3770478 A AU 3770478A AU 525064 B2 AU525064 B2 AU 525064B2
Authority
AU
Australia
Prior art keywords
butylaminopropanole
indolyl
tertiary
tertiary butylaminopropanole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU37704/78A
Other languages
English (en)
Other versions
AU3770478A (en
Inventor
E. Kreighbaum And William T. Comer William
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of AU3770478A publication Critical patent/AU3770478A/en
Application granted granted Critical
Publication of AU525064B2 publication Critical patent/AU525064B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU37704/78A 1977-07-13 1978-07-03 3-indolyl-tertiary butylaminopropanole Expired AU525064B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81513877A 1977-07-13 1977-07-13
USUS815138 1977-07-13

Publications (2)

Publication Number Publication Date
AU3770478A AU3770478A (en) 1980-01-10
AU525064B2 true AU525064B2 (en) 1982-10-21

Family

ID=25216976

Family Applications (1)

Application Number Title Priority Date Filing Date
AU37704/78A Expired AU525064B2 (en) 1977-07-13 1978-07-03 3-indolyl-tertiary butylaminopropanole

Country Status (30)

Country Link
JP (1) JPS5419972A (zh)
AR (1) AR225274A1 (zh)
AT (1) AT364821B (zh)
AU (1) AU525064B2 (zh)
BE (1) BE868943A (zh)
CA (1) CA1116598A (zh)
CH (1) CH642066A5 (zh)
CY (1) CY1274A (zh)
DE (1) DE2830884A1 (zh)
DK (1) DK156568C (zh)
ES (1) ES471674A1 (zh)
FI (1) FI69835C (zh)
FR (1) FR2397404A1 (zh)
GB (1) GB2001633B (zh)
GR (1) GR74488B (zh)
HK (1) HK1385A (zh)
HU (1) HU178992B (zh)
IE (1) IE47122B1 (zh)
IL (1) IL55115A (zh)
IT (1) IT1105091B (zh)
KE (1) KE3485A (zh)
LU (1) LU79966A1 (zh)
MY (1) MY8500946A (zh)
NL (1) NL189946C (zh)
NO (1) NO149311C (zh)
NZ (1) NZ187763A (zh)
SE (1) SE429339B (zh)
SG (1) SG82584G (zh)
YU (1) YU40528B (zh)
ZA (1) ZA783744B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463765A1 (fr) * 1979-08-17 1981-02-27 Clin Midy Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
US4321398A (en) * 1981-05-07 1982-03-23 Mead Johnson & Company Thienyl and benzothienyl-tertiary butylaminophenoxypropanols
DE3119796A1 (de) * 1981-05-19 1982-12-23 Hoechst Ag, 6000 Frankfurt Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung
FR2523964B1 (fr) * 1982-03-23 1985-09-27 Sanofi Sa Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation
NZ208337A (en) * 1983-06-10 1988-10-28 Bristol Myers Co 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2601008B1 (fr) * 1986-07-03 1990-03-30 Sanofi Sa Procede de synthese stereospecifique de derives de l'indole
US6825220B2 (en) 2000-11-10 2004-11-30 Eli Lilly And Company 3-Substituted oxindole β 3 agonists
WO2003016307A1 (en) * 2001-08-14 2003-02-27 Eli Lilly And Company β3 ADRENERGIC AGONISTS
DE60211199T2 (de) 2001-08-14 2007-02-01 Eli Lilly And Co., Indianapolis 3-substituierte oxindol-beta-3-agonisten
JP2005518357A (ja) 2001-11-20 2005-06-23 イーライ・リリー・アンド・カンパニー ベータ３アドレナリンアゴニスト
JP2005514366A (ja) 2001-11-20 2005-05-19 イーライ・リリー・アンド・カンパニー ３−置換オキシインドールβ３アゴニスト
EP1467733A1 (en) 2002-01-11 2004-10-20 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as beta3 agonists
CA2732513C (en) 2008-08-01 2017-04-25 Arca Biopharma, Inc. Methods and compositions involving (s)-bucindolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1532210A (fr) * 1963-06-21 1968-07-12 Ici Ltd Composés hétérocycliques et leur procédé de préparation
CH495983A (de) * 1968-02-09 1970-09-15 Sandoz Ag Verfahren zur Herstellung von linksdrehendem 4-(2-Hydroxy-3-isopropylaminopropoxy)indol
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines

Also Published As

Publication number Publication date
YU161178A (en) 1983-02-28
IT1105091B (it) 1985-10-28
ES471674A1 (es) 1979-10-01
DE2830884C2 (zh) 1990-01-11
IE781400L (en) 1979-01-13
JPS5419972A (en) 1979-02-15
IT7850228A0 (it) 1978-07-10
NL189946B (nl) 1993-04-16
SG82584G (en) 1985-09-13
KE3485A (en) 1985-01-25
DK313878A (da) 1979-01-14
GB2001633B (en) 1982-03-24
NL7807564A (nl) 1979-01-16
FR2397404B1 (zh) 1982-06-11
IL55115A (en) 1981-09-13
DK156568C (da) 1990-02-05
ATA508978A (de) 1981-04-15
AT364821B (de) 1981-11-25
AR225274A1 (es) 1982-03-15
DE2830884A1 (de) 1979-02-01
AU3770478A (en) 1980-01-10
NL189946C (nl) 1993-09-16
GR74488B (zh) 1984-06-28
ZA783744B (en) 1979-07-25
NZ187763A (en) 1984-07-31
YU40528B (en) 1986-02-28
FI782205A (fi) 1979-01-14
HU178992B (en) 1982-07-28
FR2397404A1 (fr) 1979-02-09
GB2001633A (en) 1979-02-07
SE7807700L (sv) 1979-01-14
NO149311B (no) 1983-12-19
NO782407L (no) 1979-01-16
IL55115A0 (en) 1978-09-29
JPS6340784B2 (zh) 1988-08-12
FI69835B (fi) 1985-12-31
MY8500946A (en) 1985-12-31
CH642066A5 (de) 1984-03-30
HK1385A (en) 1985-01-11
CY1274A (en) 1985-03-08
IE47122B1 (en) 1983-12-28
LU79966A1 (fr) 1979-04-09
CA1116598A (en) 1982-01-19
SE429339B (sv) 1983-08-29
FI69835C (fi) 1986-05-26
NO149311C (no) 1984-03-28
DK156568B (da) 1989-09-11
BE868943A (fr) 1979-01-12

Similar Documents

Publication Publication Date Title
AU3409978A (en) 4-acylaminophenyl-ethanolamines
AU3506678A (en) Polyetheramide-acids
AU3782678A (en) 1-acyl-2-cyanoaziridines
AU3662478A (en) Pyridobenzodiazepines
AU3069177A (en) Inkduct
AU3780378A (en) Circuit-tester
AU525064B2 (en) 3-indolyl-tertiary butylaminopropanole
AU3347978A (en) Phenyl-benzimidazoyl-furanes
AU3662278A (en) Pyridobenzoiazepines
AU3216278A (en) Phenylcarbamoyl-pyrazolines
AU3216478A (en) Phenylcarbamoyl-2-pyrazolines
AU3732478A (en) a-ETHYNYL TRYTOPHANES
AU3239278A (en) Dithienylalkylamines
AU3401278A (en) Sipper-seal
AU3821078A (en) Imidazo-isoquinoline-diones
AU3764478A (en) Benzylpyrimidines
AU3492478A (en) 4-alkylthio-2-trifluoromethylalkanesulfonides
AU3815178A (en) 7a-Methoxycephalosporins
AU3307178A (en) Chloroacetanylides
AU3418778A (en) Hydroxylated-1d-2d-methylene-steroids
AU3706678A (en) Pyridazinylhydrazines
AU3732678A (en) Alpha-vinyl tryptophanes
AU3246878A (en) Arylenedioxy-bis-diketones
AU3790378A (en) Amidino-benzylpyrimidines
AU3615578A (en) 17-beta-hydroxy-delta 4-androsten-3-ones