SE368401B - - Google Patents

Info

Publication number
SE368401B
SE368401B SE17063/70A SE1706370A SE368401B SE 368401 B SE368401 B SE 368401B SE 17063/70 A SE17063/70 A SE 17063/70A SE 1706370 A SE1706370 A SE 1706370A SE 368401 B SE368401 B SE 368401B
Authority
SE
Sweden
Application number
SE17063/70A
Inventor
A Rheiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE368401B publication Critical patent/SE368401B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE17063/70A 1970-01-06 1970-12-16 SE368401B (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
SE368401B true SE368401B (cs) 1974-07-01

Family

ID=4179328

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7313623A SE386672B (sv) 1970-01-06 1970-12-16 Mellanprodukter for framstellning av isokinolinderivat
SE17063/70A SE368401B (cs) 1970-01-06 1970-12-16
SE7313622A SE399879B (sv) 1970-01-06 1973-10-05 Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7313623A SE386672B (sv) 1970-01-06 1970-12-16 Mellanprodukter for framstellning av isokinolinderivat

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7313622A SE399879B (sv) 1970-01-06 1973-10-05 Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivat

Country Status (19)

Country Link
JP (1) JPS5515476B1 (cs)
AT (1) AT303041B (cs)
BE (1) BE761219A (cs)
CA (1) CA999866A (cs)
CH (2) CH527194A (cs)
DE (1) DE2062001C2 (cs)
DK (1) DK125021B (cs)
ES (1) ES387016A1 (cs)
FI (1) FI49503C (cs)
FR (1) FR2081412B1 (cs)
GB (1) GB1335261A (cs)
IE (1) IE34859B1 (cs)
IL (1) IL35916A (cs)
NL (1) NL171444C (cs)
NO (1) NO135315C (cs)
PH (1) PH9682A (cs)
SE (3) SE386672B (cs)
YU (1) YU33660B (cs)
ZA (1) ZA708590B (cs)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
CN100436420C (zh) * 1999-11-03 2008-11-26 Amr科技公司 4-苯基取代的四氢异喹啉及其用于制备药物的用途
KR100885986B1 (ko) * 1999-11-03 2009-03-03 에이엠알 테크놀로지, 인크. 노르에피네프린, 도파민 및 세로토닌의 재흡수를 방지하기위한 아릴 및 헤테로아릴 치환된테트라하이드로이소퀴놀린 및 이들의 용도
EP1113007A1 (en) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
AU7334901A (en) 2000-07-11 2002-01-21 Du Pont Pharm Co Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
WO2006020049A2 (en) 2004-07-15 2006-02-23 Amr Technology, Inc. Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
DK1899334T3 (da) * 2005-06-17 2008-11-24 Janssen Pharmaceutica Nv Naphthyridinforbindelser
JP5258561B2 (ja) 2005-07-15 2013-08-07 アルバニー モレキュラー リサーチ， インコーポレイテッド アリール置換およびヘテロアリール置換テトラヒドロベンズアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AU2010247735B2 (en) 2009-05-12 2015-07-16 Albany Molecular Research, Inc. Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydroisoquinoline and use thereof
AU2010247763B2 (en) 2009-05-12 2015-12-24 Albany Molecular Research, Inc. 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
WO2010132437A1 (en) 2009-05-12 2010-11-18 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
ZA708590B (en) 1971-09-29
DK125021B (da) 1972-12-18
DE2062001A1 (de) 1971-07-15
CH527194A (de) 1972-08-31
IE34859L (en) 1971-07-06
YU1971A (en) 1977-06-30
FI49503B (cs) 1975-04-01
FR2081412A1 (cs) 1971-12-03
CH538477A (de) 1973-06-30
PH9682A (en) 1976-02-10
JPS5515476B1 (cs) 1980-04-23
BE761219A (fr) 1971-07-05
SE386672B (sv) 1976-08-16
IL35916A (en) 1973-11-28
DE2062001C2 (de) 1986-10-16
YU33660B (en) 1977-12-31
SE399879B (sv) 1978-03-06
CA999866A (en) 1976-11-16
IE34859B1 (en) 1975-09-03
NO135315C (cs) 1977-03-23
FI49503C (fi) 1975-07-10
IL35916A0 (en) 1971-02-25
FR2081412B1 (cs) 1974-04-12
ES387016A1 (es) 1976-05-01
NO135315B (cs) 1976-12-13
NL171444B (nl) 1982-11-01
NL7018956A (cs) 1971-07-08
AT303041B (de) 1972-11-10
GB1335261A (en) 1973-10-24
NL171444C (nl) 1983-04-05

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