FI49503C - Analogiamenetelmä 1,2,3,4-tetrahydro-4-fenyyli-isokinoliinijohdannaist en valmistamiseksi. - Google Patents

Analogiamenetelmä 1,2,3,4-tetrahydro-4-fenyyli-isokinoliinijohdannaist en valmistamiseksi.

Info

Publication number
FI49503C
FI49503C FI703519A FI351970A FI49503C FI 49503 C FI49503 C FI 49503C FI 703519 A FI703519 A FI 703519A FI 351970 A FI351970 A FI 351970A FI 49503 C FI49503 C FI 49503C
Authority
FI
Finland
Prior art keywords
tetrahydro
preparation
analogous process
phenylisoquinoline derivatives
phenylisoquinoline
Prior art date
Application number
FI703519A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI49503B (cs
Inventor
Jr Alfred Rheiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of FI49503B publication Critical patent/FI49503B/fi
Publication of FI49503C publication Critical patent/FI49503C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI703519A 1970-01-06 1970-12-31 Analogiamenetelmä 1,2,3,4-tetrahydro-4-fenyyli-isokinoliinijohdannaist en valmistamiseksi. FI49503C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (2)

Publication Number Publication Date
FI49503B FI49503B (cs) 1975-04-01
FI49503C true FI49503C (fi) 1975-07-10

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
FI703519A FI49503C (fi) 1970-01-06 1970-12-31 Analogiamenetelmä 1,2,3,4-tetrahydro-4-fenyyli-isokinoliinijohdannaist en valmistamiseksi.

Country Status (19)

Country Link
JP (1) JPS5515476B1 (cs)
AT (1) AT303041B (cs)
BE (1) BE761219A (cs)
CA (1) CA999866A (cs)
CH (2) CH527194A (cs)
DE (1) DE2062001C2 (cs)
DK (1) DK125021B (cs)
ES (1) ES387016A1 (cs)
FI (1) FI49503C (cs)
FR (1) FR2081412B1 (cs)
GB (1) GB1335261A (cs)
IE (1) IE34859B1 (cs)
IL (1) IL35916A (cs)
NL (1) NL171444C (cs)
NO (1) NO135315C (cs)
PH (1) PH9682A (cs)
SE (3) SE386672B (cs)
YU (1) YU33660B (cs)
ZA (1) ZA708590B (cs)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
WO2001032625A1 (en) 1999-11-03 2001-05-10 Du Pont Pharmaceuticals Company Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
CN100436420C (zh) * 1999-11-03 2008-11-26 Amr科技公司 4-苯基取代的四氢异喹啉及其用于制备药物的用途
EP1113007A1 (en) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
CN100430401C (zh) 2000-07-11 2008-11-05 Amr科技公司 新的4-苯基取代的四氢异喹啉类化合物及其治疗用途
JP5007226B2 (ja) 2004-07-15 2012-08-22 エーエムアール テクノロジー インコーポレイテッド アリールおよびヘテロアリール置換テトラヒドロイソキノリンならびにノルエピネフリン、ドーパミン、およびセロトニンの再取り込みを遮断するためのその利用方法
DE602006002894D1 (de) 2005-06-17 2008-11-06 Janssen Pharmaceutica Nv Naphthyridinverbindungen
GEP20125566B (en) 2005-07-15 2012-07-10 Amr Technology Inc Aryl-and heteroaryl-substituded tetrahydro-benzazepines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
JP5764553B2 (ja) 2009-05-12 2015-08-19 アルバニー モレキュラー リサーチ， インコーポレイテッド ７−（［１，２，４］トリアゾロ［１，５−ａ］ピリジン−６−イル）−４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロイソキノリンおよびその使用
MX2011011900A (es) 2009-05-12 2012-01-20 Squibb Bristol Myers Co Formas cristalinas de (s)-7-([1,2,4]triazolo[1,5-a]piridin-6-il)-4 -(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina y usos de las misma.
CN102458123A (zh) 2009-05-12 2012-05-16 阿尔巴尼分子研究公司 芳基、杂芳基和杂环取代的四氢异喹啉及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
ES387016A1 (es) 1976-05-01
YU33660B (en) 1977-12-31
NL171444C (nl) 1983-04-05
NO135315C (cs) 1977-03-23
JPS5515476B1 (cs) 1980-04-23
CH538477A (de) 1973-06-30
NL171444B (nl) 1982-11-01
YU1971A (en) 1977-06-30
NO135315B (cs) 1976-12-13
ZA708590B (en) 1971-09-29
IE34859B1 (en) 1975-09-03
SE386672B (sv) 1976-08-16
BE761219A (fr) 1971-07-05
NL7018956A (cs) 1971-07-08
PH9682A (en) 1976-02-10
DE2062001A1 (de) 1971-07-15
GB1335261A (en) 1973-10-24
AT303041B (de) 1972-11-10
DK125021B (da) 1972-12-18
DE2062001C2 (de) 1986-10-16
SE368401B (cs) 1974-07-01
SE399879B (sv) 1978-03-06
CA999866A (en) 1976-11-16
IL35916A0 (en) 1971-02-25
FI49503B (cs) 1975-04-01
FR2081412A1 (cs) 1971-12-03
CH527194A (de) 1972-08-31
IE34859L (en) 1971-07-06
IL35916A (en) 1973-11-28
FR2081412B1 (cs) 1974-04-12

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