RU2721409C1 - Фармацевтические комбинации ингибитора гистондеацетилаз и ингибитора протеасом или иммуномодулирующего лекарственного средства для лечения рака крови - Google Patents
Фармацевтические комбинации ингибитора гистондеацетилаз и ингибитора протеасом или иммуномодулирующего лекарственного средства для лечения рака крови Download PDFInfo
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| KR1020160127767A KR102002581B1 (ko) | 2016-10-04 | 2016-10-04 | 혈액암 치료를 위한 hdac 저해제 및 프로테아좀 억제제 또는 면역조절성 약물을 포함하는 약학적 조합물 |
| PCT/KR2017/011015 WO2018066946A1 (en) | 2016-10-04 | 2017-09-29 | Pharmaceutical combinations of histone deacetylase inhibitor and proteasome inhibitor or immunomodulatory drug for the treatment of hematological cancer |
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| WO2013021032A1 (en) * | 2011-08-11 | 2013-02-14 | Janssen Pharmaceutica Nv | Histone deacetylase inhibitors in combination with proteasome inhibitors and dexamethasone |
| US8466161B2 (en) * | 2009-03-27 | 2013-06-18 | Chong Kun Dang Pharmaceutical Corp. | Hydroxamate derivative, a production method for the same, and a pharmaceutical composition comprising the same |
| WO2015054175A1 (en) * | 2013-10-11 | 2015-04-16 | Acetylon Pharmaceuticals, Inc. | Combinations of histone deactylase inhibitors and immunomodulatory drugs |
| EA201590345A1 (ru) * | 2012-08-09 | 2015-06-30 | Селджин Корпорейшн | Способы лечения рака с использованием 3-(4-((4-(морфолинометил)бензил)окси)-1-оксоизоиндолин-2-ил)пиперидин-2,6-диона |
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| WO2007054719A2 (en) * | 2005-11-10 | 2007-05-18 | Topotarget Uk Limited | Histone deacetylase (hdac) inhibitors (pxdlol) for the treatment of cancer alone or in combination with chemotherapeutic agent |
| PL2066327T3 (pl) * | 2006-09-15 | 2013-03-29 | Janssen Pharmaceutica Nv | Inhibitory deacetylaz histonowych o działaniu skojarzonym na deacetylazy histonowe klasy I oraz klasy IIB w kombinacji z inhibitorami proteasomu |
| WO2010085654A1 (en) * | 2009-01-23 | 2010-07-29 | Cancer Research Technology Limited | Hedgehog pathway inhibitors |
| WO2010124009A2 (en) * | 2009-04-21 | 2010-10-28 | Schering Corporation | Fully human anti-vegf antibodies and methods of using |
| US8610434B2 (en) | 2011-07-21 | 2013-12-17 | ColdEdge Technologies, Inc. | Cryogen-free cooling system for electron paramagnetic resonance system |
| PT3080125T (pt) * | 2013-12-12 | 2018-12-14 | Chong Kun Dang Pharmaceutical Corp | Novos derivados de azaindole como inibidores seletivos da histona-desacetilase (hdac) e composições farmacêuticas que compreendem os mesmos |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8466161B2 (en) * | 2009-03-27 | 2013-06-18 | Chong Kun Dang Pharmaceutical Corp. | Hydroxamate derivative, a production method for the same, and a pharmaceutical composition comprising the same |
| WO2013021032A1 (en) * | 2011-08-11 | 2013-02-14 | Janssen Pharmaceutica Nv | Histone deacetylase inhibitors in combination with proteasome inhibitors and dexamethasone |
| EA201590345A1 (ru) * | 2012-08-09 | 2015-06-30 | Селджин Корпорейшн | Способы лечения рака с использованием 3-(4-((4-(морфолинометил)бензил)окси)-1-оксоизоиндолин-2-ил)пиперидин-2,6-диона |
| WO2015054175A1 (en) * | 2013-10-11 | 2015-04-16 | Acetylon Pharmaceuticals, Inc. | Combinations of histone deactylase inhibitors and immunomodulatory drugs |
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| Title |
|---|
| D.S. Siegel et al., Vorinostat in combination with lenalidomide and dexamethasone in patients with relapsed or refractory multiple myeloma, Blood Cancer J. 2014 Feb; 4(2): e182, найдено онлайн 31.10.2019, найдено в Интернет: ttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944659/ * |
| D.S. Siegel et al., Vorinostat in combination with lenalidomide and dexamethasone in patients with relapsed or refractory multiple myeloma, Blood Cancer J. 2014 Feb; 4(2): e182, найдено онлайн 31.10.2019, найдено в Интернет: ttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944659/. * |
| Mitsiades C.S. et al., Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications. Proc Natl Acad Sci USA, 2004;101:540-545, найдено онлайн 07.11.2019, найдено в Интернет: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC327183/. * |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA201902340B (en) | 2020-08-26 |
| JP2019529562A (ja) | 2019-10-17 |
| CN109789138A (zh) | 2019-05-21 |
| EP3522891A4 (en) | 2020-04-15 |
| JP2021020953A (ja) | 2021-02-18 |
| MX2019003907A (es) | 2019-08-05 |
| BR112019006633A2 (pt) | 2019-07-02 |
| AU2017338564A1 (en) | 2019-05-02 |
| EP3522891A1 (en) | 2019-08-14 |
| KR102002581B1 (ko) | 2019-07-22 |
| CA3038019A1 (en) | 2018-04-12 |
| WO2018066946A1 (en) | 2018-04-12 |
| KR20180037507A (ko) | 2018-04-12 |
| AU2017338564B2 (en) | 2020-07-09 |
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