RU2646498C2 - Способы детектирования 5Т4-положительных циркулирующих опухолевых клеток и способы диагностики 5Т4-положительного рака у млекопитающего - Google Patents
Способы детектирования 5Т4-положительных циркулирующих опухолевых клеток и способы диагностики 5Т4-положительного рака у млекопитающего Download PDFInfo
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- G—PHYSICS
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G01N33/5759—
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
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- G01N33/575—
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- G01N33/5758—
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70589—CD45
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261590066P | 2012-01-24 | 2012-01-24 | |
| US61/590,066 | 2012-01-24 | ||
| US201361753665P | 2013-01-17 | 2013-01-17 | |
| US61/753,665 | 2013-01-17 | ||
| PCT/IB2013/050547 WO2013111054A1 (en) | 2012-01-24 | 2013-01-22 | Methods for detecting 5t4-positive circulating tumor cells and methods of diagnosis of 5t4-positive cancer in a mammalian subject |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2014127474A RU2014127474A (ru) | 2016-03-20 |
| RU2646498C2 true RU2646498C2 (ru) | 2018-03-05 |
Family
ID=47844410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2014127474A RU2646498C2 (ru) | 2012-01-24 | 2013-01-22 | Способы детектирования 5Т4-положительных циркулирующих опухолевых клеток и способы диагностики 5Т4-положительного рака у млекопитающего |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10254286B2 (enExample) |
| EP (1) | EP2807485B1 (enExample) |
| JP (1) | JP6254951B2 (enExample) |
| KR (1) | KR101716555B1 (enExample) |
| CN (1) | CN104094116B (enExample) |
| AU (2) | AU2013213301A1 (enExample) |
| BR (1) | BR112014018192A8 (enExample) |
| CA (1) | CA2861437C (enExample) |
| ES (1) | ES2724232T3 (enExample) |
| IL (1) | IL233543B (enExample) |
| IN (1) | IN2014DN07019A (enExample) |
| MX (1) | MX361058B (enExample) |
| RU (1) | RU2646498C2 (enExample) |
| WO (1) | WO2013111054A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2845800C1 (ru) * | 2024-12-24 | 2025-08-25 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Красноярский государственный медицинский университет имени профессора В.Ф.Войно-Ясенецкого" Министерства здравоохранения Российской Федерации | Способ дифференциальной диагностики рака мочевого пузыря, рака почки и рака легкого |
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| JP2803804B2 (ja) | 1992-08-21 | 1998-09-24 | 株式会社長澤製作所 | ボタン錠 |
| CN102782498A (zh) | 2009-10-21 | 2012-11-14 | 斯克里普斯研究所 | 用非稀有细胞检测稀有细胞的方法 |
| US8956859B1 (en) | 2010-08-13 | 2015-02-17 | Aviex Technologies Llc | Compositions and methods for determining successful immunization by one or more vaccines |
| WO2015172038A1 (en) * | 2014-05-09 | 2015-11-12 | The Scripps Research Institute | Compositions and methods for fluid biopsy of melanoma |
| US20150185204A1 (en) * | 2013-12-30 | 2015-07-02 | The Scripps Research Institute | Circulating tumor cell diagnostics for lung cancer |
| WO2015112955A1 (en) | 2014-01-27 | 2015-07-30 | Epic Sciences, Inc. | Circulating tumor cell diagnostics for prostate cancer biomarkers |
| US10545151B2 (en) * | 2014-02-21 | 2020-01-28 | Epic Sciences, Inc. | Methods for analyzing rare circulating cells |
| WO2015155345A1 (en) * | 2014-04-11 | 2015-10-15 | Medimmune Limited | Antibodies and antibody-drug conjugates |
| JP6657509B2 (ja) * | 2014-08-25 | 2020-03-04 | クリエイティブ マイクロテック インコーポレイテッドCreatv Microtech, Inc. | 疾患の検出及び診断のための血液中の循環細胞バイオマーカーの使用並びにそれらを単離する方法 |
| CN113552350B (zh) * | 2015-04-21 | 2024-10-11 | 基因泰克公司 | 用于前列腺癌分析的组合物和方法 |
| KR102696044B1 (ko) * | 2015-11-06 | 2024-08-16 | 벤타나 메디컬 시스템즈, 인코포레이티드 | 대표 진단법 |
| KR20170099738A (ko) | 2016-02-23 | 2017-09-01 | 노을 주식회사 | 접촉식 염색 패치 및 그 제조 방법 |
| KR102478639B1 (ko) | 2016-02-23 | 2022-12-19 | 노을 주식회사 | 표지 물질을 저장하는 패치, 이를 이용하는 조직 진단 방법 및 장치 |
| KR102406596B1 (ko) * | 2016-02-23 | 2022-06-10 | 노을 주식회사 | 패치를 이용하는 ctc 진단 방법 및 장치 |
| KR102045069B1 (ko) * | 2016-02-23 | 2019-11-15 | 노을 주식회사 | 패치를 이용하는 ctc 진단 방법 및 장치 |
| US10371610B2 (en) | 2016-02-23 | 2019-08-06 | Noul Co., Ltd. | Contact-type patch, staining method using the same, and manufacturing method thereof |
| RU2019134462A (ru) | 2017-04-03 | 2021-05-05 | Ф. Хоффманн-Ля Рош Аг | Антитела, связывающиеся с steap-1 |
| CN111033238A (zh) * | 2017-06-27 | 2020-04-17 | 定量癌症诊断有限责任公司 | 定量的液体活检诊断系统与方法 |
| CN107918013A (zh) * | 2017-09-25 | 2018-04-17 | 浙江天科高新技术发展有限公司 | 化学发光酶免测定循环肿瘤细胞中K‑Ras蛋白的方法及试剂盒 |
| JP7678424B2 (ja) | 2018-05-10 | 2025-05-16 | 学校法人順天堂 | 画像解析方法、装置、コンピュータプログラム、及び深層学習アルゴリズムの生成方法 |
| WO2020086882A1 (en) * | 2018-10-24 | 2020-04-30 | Northwestern University | Tumor cell aggregation inhibitors' for treating cancer |
| JP7381003B2 (ja) * | 2019-04-26 | 2023-11-15 | 学校法人順天堂 | 疾患解析を支援する方法、装置、及びコンピュータプログラム、並びにコンピュータアルゴリズムを訓練する方法、装置、及びプログラム |
| US20230175073A1 (en) | 2021-12-07 | 2023-06-08 | Epic Sciences, Inc. | Enhanced characterization of breast cancer |
Citations (2)
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| WO2007089911A2 (en) * | 2006-01-30 | 2007-08-09 | The Scripps Research Institute | Methods for detection of circulating tumor cells and methods of diagnosis of cancer in a mammalian subject |
| WO2010070276A1 (en) * | 2008-12-15 | 2010-06-24 | Oxford Biomedica (Uk) Limited | Method |
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| US4391904A (en) | 1979-12-26 | 1983-07-05 | Syva Company | Test strip kits in immunoassays and compositions therein |
| US5869053A (en) | 1988-03-04 | 1999-02-09 | Cancer Research Campaign Technology, Ltd. | 5T4 antigen from human trophoblasts |
| EP0336562B1 (en) | 1988-03-04 | 1995-06-14 | Cancer Research Campaign Technology Ltd. | Improvements relating to antigens |
| JP2002507117A (ja) | 1997-06-04 | 2002-03-05 | オックスフォード・バイオメディカ・(ユーケイ)・リミテッド | ベクター |
| JP2003515323A (ja) | 1999-11-18 | 2003-05-07 | オックスフォード バイオメディカ(ユーケイ)リミテッド | 抗 体 |
| GB0126378D0 (en) | 2001-11-02 | 2002-01-02 | Oxford Biomedica Ltd | Antigen |
| US7305112B2 (en) | 2002-10-15 | 2007-12-04 | The Scripps Research Institute | Method of converting rare cell scanner image coordinates to microscope coordinates using reticle marks on a sample media |
| KR20070050956A (ko) * | 2004-09-10 | 2007-05-16 | 와이어쓰 | 사람화 항-5t4 항체 및 항-5t4 항체/칼리케아미신 접합체 |
| JP5523824B2 (ja) | 2006-03-10 | 2014-06-18 | ワイス・エルエルシー | 抗−5t4抗体およびその使用 |
| US20100233693A1 (en) | 2007-04-16 | 2010-09-16 | On-O-ity, Inc | Methods for diagnosing, prognosing, or theranosing a condition using rare cells |
| CN102414562B (zh) | 2009-03-24 | 2019-05-07 | 生物概念股份有限公司 | 细胞捕获和分析的装置和方法 |
| CA2754610C (en) | 2009-03-27 | 2015-05-05 | Marc Isaac Damelin | Tumor-initiating cells and methods for using same |
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| CN102782498A (zh) | 2009-10-21 | 2012-11-14 | 斯克里普斯研究所 | 用非稀有细胞检测稀有细胞的方法 |
| CA2795776A1 (en) * | 2010-04-06 | 2011-10-13 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Circulating biomarkers for disease |
| EP2591363B1 (en) | 2010-07-07 | 2017-09-20 | The Regents Of The University Of Michigan | Diagnosis and treatment of breast cancer |
| AU2012235817B2 (en) | 2011-04-01 | 2016-03-10 | Wyeth Llc | Antibody-drug conjugates |
-
2013
- 2013-01-22 ES ES13708526T patent/ES2724232T3/es active Active
- 2013-01-22 BR BR112014018192A patent/BR112014018192A8/pt not_active Application Discontinuation
- 2013-01-22 AU AU2013213301A patent/AU2013213301A1/en not_active Abandoned
- 2013-01-22 IN IN7019DEN2014 patent/IN2014DN07019A/en unknown
- 2013-01-22 CA CA2861437A patent/CA2861437C/en not_active Expired - Fee Related
- 2013-01-22 WO PCT/IB2013/050547 patent/WO2013111054A1/en not_active Ceased
- 2013-01-22 US US14/374,083 patent/US10254286B2/en not_active Expired - Fee Related
- 2013-01-22 MX MX2014008928A patent/MX361058B/es active IP Right Grant
- 2013-01-22 JP JP2014553836A patent/JP6254951B2/ja not_active Expired - Fee Related
- 2013-01-22 EP EP13708526.2A patent/EP2807485B1/en active Active
- 2013-01-22 RU RU2014127474A patent/RU2646498C2/ru active
- 2013-01-22 KR KR1020147020394A patent/KR101716555B1/ko not_active Expired - Fee Related
- 2013-01-22 CN CN201380006333.9A patent/CN104094116B/zh not_active Expired - Fee Related
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- 2014-07-07 IL IL233543A patent/IL233543B/en active IP Right Grant
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007089911A2 (en) * | 2006-01-30 | 2007-08-09 | The Scripps Research Institute | Methods for detection of circulating tumor cells and methods of diagnosis of cancer in a mammalian subject |
| WO2010070276A1 (en) * | 2008-12-15 | 2010-06-24 | Oxford Biomedica (Uk) Limited | Method |
Non-Patent Citations (3)
| Title |
|---|
| MYERS K.A. et al. Metastasis-associated 5T4 antigen disrupts cell-cell contacts and induces cellular motility in epithelial cells// International Journal of Cancer Volume 68, Issue 1, pages 84-92, 27 September 1996 [он лайн] [найдено 10.11.2015] найдено в Интернет: 3.0.CO;2-6/epdf"http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1097-0215(19960927)68:1<84::AID-IJC15>3.0.CO;2-6/epdf. * |
| ZHAO Y et al. 5T4 oncotrophoblast glycoprotein: janus molecule in life and a novel potential target against tumors// Cell Mol Immunol. 2007 Apr;4(2):99-104 [он лайн] [найдено 10.11.2015] найденов Интернет: http://www.cm.ustc.edu.cn/4/2/99.pdf . * |
| ZHAO Y et al. 5T4 oncotrophoblast glycoprotein: janus molecule in life and a novel potential target against tumors// Cell Mol Immunol. 2007 Apr;4(2):99-104 [он лайн] [найдено 10.11.2015] найденов Интернет: http://www.cm.ustc.edu.cn/4/2/99.pdf . MYERS K.A. et al. Metastasis-associated 5T4 antigen disrupts cell-cell contacts and induces cellular motility in epithelial cells// International Journal of Cancer Volume 68, Issue 1, pages 84-92, 27 September 1996 [он лайн] [найдено 10.11.2015] найдено в Интернет: 3.0.CO;2-6/epdf"http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1097-0215(19960927)68:1<84::AID-IJC15>3.0.CO;2-6/epdf. * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2845800C1 (ru) * | 2024-12-24 | 2025-08-25 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Красноярский государственный медицинский университет имени профессора В.Ф.Войно-Ясенецкого" Министерства здравоохранения Российской Федерации | Способ дифференциальной диагностики рака мочевого пузыря, рака почки и рака легкого |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6254951B2 (ja) | 2017-12-27 |
| CA2861437A1 (en) | 2013-08-01 |
| KR101716555B1 (ko) | 2017-03-14 |
| CN104094116B (zh) | 2017-05-31 |
| RU2014127474A (ru) | 2016-03-20 |
| CN104094116A (zh) | 2014-10-08 |
| AU2013213301A1 (en) | 2014-07-17 |
| US20150017661A1 (en) | 2015-01-15 |
| CA2861437C (en) | 2018-08-21 |
| WO2013111054A1 (en) | 2013-08-01 |
| MX2014008928A (es) | 2014-10-24 |
| BR112014018192A8 (pt) | 2021-03-02 |
| IL233543A0 (en) | 2014-08-31 |
| EP2807485B1 (en) | 2019-03-13 |
| IL233543B (en) | 2018-02-28 |
| IN2014DN07019A (enExample) | 2015-04-10 |
| HK1202923A1 (en) | 2015-10-09 |
| ES2724232T3 (es) | 2019-09-09 |
| KR20140100580A (ko) | 2014-08-14 |
| MX361058B (es) | 2018-11-23 |
| EP2807485A1 (en) | 2014-12-03 |
| AU2018220154A1 (en) | 2018-09-13 |
| US10254286B2 (en) | 2019-04-09 |
| JP2015507190A (ja) | 2015-03-05 |
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