IN2014DN07019A - - Google Patents

Info

Publication number
IN2014DN07019A
IN2014DN07019A IN7019DEN2014A IN2014DN07019A IN 2014DN07019 A IN2014DN07019 A IN 2014DN07019A IN 7019DEN2014 A IN7019DEN2014 A IN 7019DEN2014A IN 2014DN07019 A IN2014DN07019 A IN 2014DN07019A
Authority
IN
India
Prior art keywords
positive
methods
cancer
mammalian subject
diagnosing
Prior art date
Application number
Inventor
Hans Peter Gerber
Dena Marrinucci
Shepherd Steven Pirie
Eric Tucker
Original Assignee
Pfizer
Epic Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer, Epic Sciences Inc filed Critical Pfizer
Publication of IN2014DN07019A publication Critical patent/IN2014DN07019A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70589CD45

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Oncology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Methods are provided for detecting 5T4 positive circulating tumor cells in a mammalian subject. Methods of diagnosing 5T4 positive cancer in a mammalian subject are provided. The methods of detection or diagnosis indicate the presence of 5T4 positive metastatic cancer or early stage 5T4 positive cancer.
IN7019DEN2014 2012-01-24 2013-01-22 IN2014DN07019A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261590066P 2012-01-24 2012-01-24
US201361753665P 2013-01-17 2013-01-17
PCT/IB2013/050547 WO2013111054A1 (en) 2012-01-24 2013-01-22 Methods for detecting 5t4-positive circulating tumor cells and methods of diagnosis of 5t4-positive cancer in a mammalian subject

Publications (1)

Publication Number Publication Date
IN2014DN07019A true IN2014DN07019A (en) 2015-04-10

Family

ID=47844410

Family Applications (1)

Application Number Title Priority Date Filing Date
IN7019DEN2014 IN2014DN07019A (en) 2012-01-24 2013-01-22

Country Status (14)

Country Link
US (1) US10254286B2 (en)
EP (1) EP2807485B1 (en)
JP (1) JP6254951B2 (en)
KR (1) KR101716555B1 (en)
CN (1) CN104094116B (en)
AU (2) AU2013213301A1 (en)
BR (1) BR112014018192A8 (en)
CA (1) CA2861437C (en)
ES (1) ES2724232T3 (en)
IL (1) IL233543B (en)
IN (1) IN2014DN07019A (en)
MX (1) MX361058B (en)
RU (1) RU2646498C2 (en)
WO (1) WO2013111054A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2803804B2 (en) 1992-08-21 1998-09-24 株式会社長澤製作所 Button lock
CN107422127A (en) 2009-10-21 2017-12-01 斯克里普斯研究所 With the method for non-rare cell detection rare cell
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
US20150185204A1 (en) * 2013-12-30 2015-07-02 The Scripps Research Institute Circulating tumor cell diagnostics for lung cancer
WO2015112955A1 (en) 2014-01-27 2015-07-30 Epic Sciences, Inc. Circulating tumor cell diagnostics for prostate cancer biomarkers
WO2015127008A1 (en) 2014-02-21 2015-08-27 Epic Sciences, Inc. Methods for analyzing rare circulating cells
WO2015155345A1 (en) * 2014-04-11 2015-10-15 Medimmune Limited Antibodies and antibody-drug conjugates
EP3140656B1 (en) * 2014-05-09 2021-02-17 The Scripps Research Institute Compositions and methods for fluid biopsy of melanoma
CN112877426A (en) * 2014-08-25 2021-06-01 创新微技术公司 Application of circulating cell biomarker in blood in detecting and diagnosing diseases and separation method thereof
JP6815331B2 (en) * 2015-04-21 2021-01-20 ジェネンテック, インコーポレイテッド Compositions and Methods for Prostate Cancer Analysis
RU2743169C2 (en) * 2015-11-06 2021-02-15 Вентана Медикал Системз, Инк. Representative diagnosis
KR102406596B1 (en) * 2016-02-23 2022-06-10 노을 주식회사 Circulating tumor cell diagnosis method using the patch and device using the same
KR102045068B1 (en) * 2016-02-23 2019-11-15 노을 주식회사 Polymerase chain reaction patch, diagnostic method using the patch and device using the same
KR102478639B1 (en) 2016-02-23 2022-12-19 노을 주식회사 Labeling substance storing patch, tissue diagnostic method using the patch and device using the same
US10371610B2 (en) 2016-02-23 2019-08-06 Noul Co., Ltd. Contact-type patch, staining method using the same, and manufacturing method thereof
KR20170099738A (en) 2016-02-23 2017-09-01 노을 주식회사 Contact-type staining patch and manufacturing method thereof
AU2018247767B2 (en) 2017-04-03 2025-01-30 F. Hoffmann-La Roche Ag Antibodies binding to STEAP-1
EP3646010A4 (en) * 2017-06-27 2020-11-11 Qcdx, Llc Quantitative liquid biopsy diagnostic system and methods
CN107918013A (en) * 2017-09-25 2018-04-17 浙江天科高新技术发展有限公司 The method and kit of K Ras albumen in chemiluminescence Enzyme immunoassay circulating tumor cell
JP7678424B2 (en) 2018-05-10 2025-05-16 学校法人順天堂 Image analysis method, device, computer program, and method for generating deep learning algorithm
US20220002429A1 (en) * 2018-10-24 2022-01-06 Northwestern University Tumor cell aggregation inhibitors' for treating cancer
JP7381003B2 (en) * 2019-04-26 2023-11-15 学校法人順天堂 METHODS, APPARATUS AND COMPUTER PROGRAMS TO ASSIST DISEASE ANALYSIS AND METHODS, APPARATUS AND PROGRAMS FOR TRAINING COMPUTER ALGORITHM
WO2023107566A1 (en) 2021-12-07 2023-06-15 Epic Sciences, Inc. Enhanced characterization of breast cancer

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4391904A (en) 1979-12-26 1983-07-05 Syva Company Test strip kits in immunoassays and compositions therein
WO1989007947A1 (en) 1988-03-04 1989-09-08 Cancer Research Campaign Technology Limited Improvements relating to antigens
US5869053A (en) 1988-03-04 1999-02-09 Cancer Research Campaign Technology, Ltd. 5T4 antigen from human trophoblasts
US6852703B1 (en) 1997-06-04 2005-02-08 Oxford Biomedica (Uk) Limited Tumor targeted vector
CA2391925A1 (en) 1999-11-18 2001-05-25 Oxford Biomedica (Uk) Limited Antibodies
GB0126378D0 (en) 2001-11-02 2002-01-02 Oxford Biomedica Ltd Antigen
US7305112B2 (en) 2002-10-15 2007-12-04 The Scripps Research Institute Method of converting rare cell scanner image coordinates to microscope coordinates using reticle marks on a sample media
CN101035564A (en) * 2004-09-10 2007-09-12 惠氏公司 Humanized anti-5T4 antibodies and anti-5T4 antibody/calicheamicin conjugates
JP2009525468A (en) * 2006-01-30 2009-07-09 ザ・スクリプス・リサーチ・インステイチユート Method for detecting circulating tumor cells and method for diagnosing cancer in a mammalian subject
CA2645097C (en) 2006-03-10 2019-09-17 Wyeth Anti-5t4 antibodies and uses thereof
WO2008131035A2 (en) 2007-04-16 2008-10-30 Cellpoint Diagnotics, Inc. Methods for diagnosing, prognosing, or theranosing a condition using rare cells
GB0822836D0 (en) * 2008-12-15 2009-01-21 Oxford Biomedica Ltd Method
EP2995953B1 (en) 2009-03-24 2017-11-29 Biocept, Inc. Devices and methods of cell capture and analysis
WO2010111659A1 (en) 2009-03-27 2010-09-30 Wyeth Llc Tumor-initiating cells and methods for using same
WO2011028905A1 (en) 2009-09-03 2011-03-10 The Scripps Research Institute Method for categorizing circulating tumor cells
CN107422127A (en) 2009-10-21 2017-12-01 斯克里普斯研究所 With the method for non-rare cell detection rare cell
KR20130043104A (en) * 2010-04-06 2013-04-29 카리스 라이프 사이언스 룩셈부르크 홀딩스 Circulating biomarkers for disease
EP3306321A1 (en) * 2010-07-07 2018-04-11 The Regents of The University of Michigan Diagnosis and treatment of breast cancer
JP5925875B2 (en) 2011-04-01 2016-05-25 ワイス・エルエルシー Antibody-drug conjugate

Also Published As

Publication number Publication date
CA2861437C (en) 2018-08-21
EP2807485B1 (en) 2019-03-13
AU2018220154A1 (en) 2018-09-13
ES2724232T3 (en) 2019-09-09
IL233543A0 (en) 2014-08-31
US20150017661A1 (en) 2015-01-15
WO2013111054A1 (en) 2013-08-01
EP2807485A1 (en) 2014-12-03
MX361058B (en) 2018-11-23
IL233543B (en) 2018-02-28
KR101716555B1 (en) 2017-03-14
CA2861437A1 (en) 2013-08-01
MX2014008928A (en) 2014-10-24
CN104094116B (en) 2017-05-31
JP2015507190A (en) 2015-03-05
US10254286B2 (en) 2019-04-09
RU2646498C2 (en) 2018-03-05
HK1202923A1 (en) 2015-10-09
CN104094116A (en) 2014-10-08
BR112014018192A8 (en) 2021-03-02
KR20140100580A (en) 2014-08-14
JP6254951B2 (en) 2017-12-27
AU2013213301A1 (en) 2014-07-17
RU2014127474A (en) 2016-03-20

Similar Documents

Publication Publication Date Title
IN2014DN07019A (en)
IL225646A0 (en) Methods and kits for the detection of circulating tumor cells in pancreatic patients using polyspecific capture and cocktail detection reagents
MX2013000917A (en) Methods of detecting diseases or conditions using phagocytic cells.
EP2524059A4 (en) Detection of gastrointestinal disorders
GB2545361A (en) Protein biomarker panels for detecting colorectal cancer and advanced adenoma
GB2519906A (en) Methods and systems for detecting biological components
EP4060048A3 (en) Non-invasive diagnostic method for diagnosing bladder cancer
MY197809A (en) Biomarkers and methods of treating pd-1 and pd-l1 related conditions
MY170983A (en) Biomarker assays for detecting or measuring inhibition of tor kinase activity
WO2013138522A3 (en) Methods for assessing effectiveness and monitoring oncolytic virus treatment
MX358117B (en) Methods and nucleic acids for determining the prognosis of a cancer subject.
EP4219765A3 (en) Prostate cancer prognosis using biomarkers
WO2012135844A3 (en) Circulating exosomes as diagnostic/prognostic indicators and therapeutic targets of melanoma and other cancers
WO2013036543A3 (en) Molecular imaging of cancer cells in vivo
EP2833149A4 (en) Method for detecting degree of malignancy of circulating tumor cell unit, and kit for same
EP3100046A4 (en) Detection of prostate specific membrane antigen (psma) expression on circulating tumor cells (ctc)
WO2011112903A3 (en) Quantitative rt-pcr detection for genes involved in epithelial mesenchymal transition in peripheral blood of breast cancer patients
WO2012012694A3 (en) Methods of detecting autoimmune or immune-related diseases or conditions
HK1220253A1 (en) Methods of detecting prostate cancer
GB201603128D0 (en) Biomarkers useful for detection of types, grades and stages of human breast cancer
EP2619332A4 (en) Direct blood assay for detection of circulating microrna in cancer patients
WO2013081645A3 (en) Erbb3 mutations in cancer
EP2855705A4 (en) METHOD OF DIAGNOSING CANCER COMPRISING THE DETECTION OF THE METHYLATION SIGNATURE IN THE HTERT PROMOTER
WO2013040358A3 (en) Assays and compositions for detection of agr2
SG11201506406XA (en) Method for detecting shed or circulating tumor cells in biological fluids