RU2632965C2 - Мягкие жевательные фармацевтические продукты - Google Patents
Мягкие жевательные фармацевтические продукты Download PDFInfo
- Publication number
- RU2632965C2 RU2632965C2 RU2014144001A RU2014144001A RU2632965C2 RU 2632965 C2 RU2632965 C2 RU 2632965C2 RU 2014144001 A RU2014144001 A RU 2014144001A RU 2014144001 A RU2014144001 A RU 2014144001A RU 2632965 C2 RU2632965 C2 RU 2632965C2
- Authority
- RU
- Russia
- Prior art keywords
- ingredients
- pharmaceutically acceptable
- acceptable salt
- methyl
- soft
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
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- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
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- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
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- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
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- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
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- A61K9/5123—Organic compounds, e.g. fats, sugars
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- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Botany (AREA)
- Mechanical Engineering (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12163198 | 2012-04-04 | ||
| EP12163198.0 | 2012-04-04 | ||
| US201361782434P | 2013-03-14 | 2013-03-14 | |
| US61/782,434 | 2013-03-14 | ||
| PCT/EP2013/056987 WO2013150052A1 (en) | 2012-04-04 | 2013-04-03 | Soft chewable pharmaceutical products |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017133665A Division RU2765231C2 (ru) | 2012-04-04 | 2013-04-03 | Мягкие жевательные фармацевтические продукты |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2014144001A RU2014144001A (ru) | 2016-05-27 |
| RU2632965C2 true RU2632965C2 (ru) | 2017-10-11 |
Family
ID=49300034
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017133665A RU2765231C2 (ru) | 2012-04-04 | 2013-04-03 | Мягкие жевательные фармацевтические продукты |
| RU2014144001A RU2632965C2 (ru) | 2012-04-04 | 2013-04-03 | Мягкие жевательные фармацевтические продукты |
| RU2014144360A RU2646483C2 (ru) | 2012-04-04 | 2013-04-03 | Твердые фармацевтические композиции для перорального введения на основе изоксазолиновых соединений |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2017133665A RU2765231C2 (ru) | 2012-04-04 | 2013-04-03 | Мягкие жевательные фармацевтические продукты |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2014144360A RU2646483C2 (ru) | 2012-04-04 | 2013-04-03 | Твердые фармацевтические композиции для перорального введения на основе изоксазолиновых соединений |
Country Status (14)
| Country | Link |
|---|---|
| US (15) | US20150057321A1 (OSRAM) |
| EP (2) | EP2833867B2 (OSRAM) |
| JP (2) | JP6088637B2 (OSRAM) |
| KR (1) | KR102077874B1 (OSRAM) |
| CN (4) | CN109010296A (OSRAM) |
| AU (7) | AU2013245008B2 (OSRAM) |
| BR (3) | BR122022008957B1 (OSRAM) |
| CA (2) | CA2869242C (OSRAM) |
| ES (1) | ES2633611T5 (OSRAM) |
| FI (1) | FI2833866T4 (OSRAM) |
| NZ (1) | NZ631100A (OSRAM) |
| RU (3) | RU2765231C2 (OSRAM) |
| WO (2) | WO2013150052A1 (OSRAM) |
| ZA (2) | ZA201406968B (OSRAM) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3216448T (pt) | 2012-02-06 | 2019-07-08 | Boehringer Ingelheim Animal Health Usa Inc | Composições veterinárias orais parasiticidas que compreendem agentes, métodos e métodos ativos que agem sistemicamente |
| WO2013150052A1 (en) | 2012-04-04 | 2013-10-10 | Intervet International B.V. | Soft chewable pharmaceutical products |
| US9532946B2 (en) | 2012-11-20 | 2017-01-03 | Intervet Inc. | Manufacturing of semi-plastic pharmaceutical dosage units |
| RU2673723C1 (ru) * | 2013-12-10 | 2018-11-29 | Интервет Интернэшнл Б.В. | Применение содержащих изоксазолин соединений в качестве противопаразитарных средств |
| ES2950885T3 (es) * | 2013-12-20 | 2023-10-16 | Intervet Int Bv | Uso de compuestos de isoxazolina en aves de corral |
| PL3082867T3 (pl) | 2013-12-20 | 2024-05-13 | Intervet International B.V. | Kompozycje izoksazoliny i ich zastosowanie w zapobieganiu lub leczeniu inwazji pasożytów u zwierząt |
| US20170354593A1 (en) * | 2014-11-03 | 2017-12-14 | Zoetis Services Llc | Palatable chewable veterinary composition |
| RU2709198C2 (ru) | 2014-12-22 | 2019-12-17 | Интервет Интернэшнл Б.В. | Применение изоксазолиновых соединений для лечения демодекоза |
| UY36570A (es) | 2015-02-26 | 2016-10-31 | Merial Inc | Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas |
| UY37137A (es) | 2016-02-24 | 2017-09-29 | Merial Inc | Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos |
| WO2018039508A1 (en) | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
| WO2018081733A1 (en) * | 2016-10-31 | 2018-05-03 | The California Institute For Biomedical Research | Methods and compositions for preventing vector-borne disease transmission |
| WO2019021191A1 (en) | 2017-07-26 | 2019-01-31 | Tgx Soft Chew, Llc | STARCH-FREE MOUTH PRODUCT FOR VETERINARY APPLICATIONS |
| AR113997A1 (es) | 2017-12-21 | 2020-07-08 | Intervet Int Bv | Composiciones antiparasitarias para unción dorsal continua |
| HRP20241712T1 (hr) * | 2018-09-05 | 2025-02-14 | Zoetis Services Llc | Antiparazitske formulacije prihvatljivog okusa |
| CA3138263A1 (en) * | 2019-05-03 | 2020-11-12 | Intervet International B.V. | Injectable pharmaceutical compositions and uses thereof |
| CA3146043A1 (en) * | 2019-07-22 | 2021-01-28 | Intervet International B.V. | Soft chewable veterinary dosage form |
| EP4075981A1 (en) * | 2019-12-16 | 2022-10-26 | Intervet International B.V. | Composition for lice control |
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