RU2587330C2 - Применение разагилина для лечения обонятельной дисфункции - Google Patents
Применение разагилина для лечения обонятельной дисфункции Download PDFInfo
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- RU2587330C2 RU2587330C2 RU2013108258/15A RU2013108258A RU2587330C2 RU 2587330 C2 RU2587330 C2 RU 2587330C2 RU 2013108258/15 A RU2013108258/15 A RU 2013108258/15A RU 2013108258 A RU2013108258 A RU 2013108258A RU 2587330 C2 RU2587330 C2 RU 2587330C2
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- razagilin
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US40046410P | 2010-07-27 | 2010-07-27 | |
| US61/400,464 | 2010-07-27 | ||
| US201161437212P | 2011-01-28 | 2011-01-28 | |
| US61/437,212 | 2011-01-28 | ||
| PCT/US2011/045574 WO2012015950A1 (en) | 2010-07-27 | 2011-07-27 | Use of rasagiline for the treatment of olfactory dysfunction |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2013108258A RU2013108258A (ru) | 2014-09-10 |
| RU2587330C2 true RU2587330C2 (ru) | 2016-06-20 |
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| RU2013108258/15A RU2587330C2 (ru) | 2010-07-27 | 2011-07-27 | Применение разагилина для лечения обонятельной дисфункции |
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| Country | Link |
|---|---|
| US (1) | US8569379B2 (OSRAM) |
| EP (1) | EP2603212A4 (OSRAM) |
| JP (1) | JP2013533287A (OSRAM) |
| AU (1) | AU2011282720B2 (OSRAM) |
| CA (1) | CA2806740A1 (OSRAM) |
| RU (1) | RU2587330C2 (OSRAM) |
| WO (1) | WO2012015950A1 (OSRAM) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2713786C1 (ru) * | 2019-05-24 | 2020-02-07 | Сергей Геннадиевич Вахрушев | Способ лечения пациентов с обонятельной дисфункцией при атрофическом рините |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP1991214B1 (en) * | 2006-02-21 | 2015-08-05 | Teva Pharmaceutical Industries, Ltd. | Use of rasagiline for the treatment of multiple system atrophy |
| US8946300B2 (en) | 2006-04-03 | 2015-02-03 | Teva Pharmaceutical Industries, Ltd. | Use of rasagilline for the treatment of restless legs syndrome |
| ATE528989T1 (de) * | 2006-12-14 | 2011-11-15 | Teva Pharma | Kristalline feste rasagilin-base |
| EP1987816A1 (de) * | 2007-04-30 | 2008-11-05 | Ratiopharm GmbH | Adsorbate eines Rasagilinsalzes mit einem wasserlöslichen Hilfsstoff |
| NZ586025A (en) * | 2008-01-11 | 2012-08-31 | Teva Pharma | Rasagiline mesylate tablet coated with a composisiton comprising methacrylic acid - ethyl acrylate copolymer and triethyl citrate |
| WO2009151594A1 (en) * | 2008-06-10 | 2009-12-17 | Teva Pharmaceutical Industries, Ltd. | Rasagiline soft gelatin capsules |
| HRP20140845T1 (hr) | 2009-07-09 | 2014-11-07 | Ratiopharm Gmbh | Soli rasagilina i farmaceutski pripravci od njih |
| US20110130466A1 (en) * | 2009-10-09 | 2011-06-02 | Stefan Lorenzl | Use of rasagiline for the treatment of progressive supranuclear palsy |
| EP2939669A1 (en) * | 2009-12-22 | 2015-11-04 | Teva Pharmaceutical Industries, Ltd. | 3-keto-n-propargyl-1-aminoindan |
| RU2013108256A (ru) | 2010-07-27 | 2014-09-10 | Тева Фармасьютикал Индастриз Лтд. | Дисперсии цитрата разагилина |
| EA201490761A1 (ru) | 2011-10-10 | 2014-11-28 | Тева Фармасьютикал Индастриз Лтд. | R(+)-n-формилпропаргиламиноиндан |
| US9339469B2 (en) | 2011-10-10 | 2016-05-17 | Teva Pharmaceutical Industries, Ltd. | R(+)-N-methyl-propargyl-aminoindan |
| JP2015529196A (ja) | 2012-08-17 | 2015-10-05 | テバ ファーマシューティカル インダストリーズ リミティド | ラサギリンの非経口製剤 |
Citations (2)
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|---|---|---|---|---|
| WO2009003147A1 (en) * | 2007-06-26 | 2008-12-31 | Parkinson's Institute | Methods and compositions for the treatment of neurological disorders |
| RU2373197C2 (ru) * | 2004-03-30 | 2009-11-20 | Тайсо Фармасьютикал Ко., Лтд. | Пиримидиновые производные, обладающие активностью в отношении мсн |
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| US5744500A (en) | 1990-01-03 | 1998-04-28 | Teva Pharmaceutical Industries, Ltd. | Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof |
| IL92952A (en) | 1990-01-03 | 1994-06-24 | Teva Pharma | R-enantiomers of n-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them |
| IL99759A (en) | 1991-10-16 | 1997-06-10 | Teva Pharma | Mono-fluorinated derivatives of n-propargyl-1-aminoindan, their preparation and pharmaceutical compositions containing them |
| IL115357A (en) | 1995-09-20 | 2000-01-31 | Teva Pharma | Stable compositions containing N-propargyl-1-aminoindan and polyhydric alcohols |
| IL118836A (en) | 1996-07-11 | 2001-01-11 | Teva Pharma | Pharmaceutical compositions comprising s-(-)-n-propargyl-1-aminoindan |
| ATE377585T1 (de) | 1996-12-18 | 2007-11-15 | Teva Pharma | Aminoindanderivate |
| US7326690B2 (en) | 2002-10-30 | 2008-02-05 | Bach Pharma, Inc. | Modulation of cell fates and activities by phthalazinediones |
| US7396860B2 (en) | 2002-11-15 | 2008-07-08 | Teva Pharmaceutical Industries, Ltd. | Use of rasagiline with or without riluzole to treat amyotrophic lateral sclerosis |
| EP1778196A4 (en) | 2004-07-26 | 2008-12-17 | Teva Pharma | PHARMACEUTICAL DOSAGES CONTAINING RASAGILINE |
| ES2371883T3 (es) | 2004-11-24 | 2012-01-11 | Teva Pharmaceutical Industries Ltd. | Composiciones de rasagilina de disgregación oral. |
| AU2006216696B2 (en) | 2005-02-23 | 2011-08-18 | Teva Pharmaceutical Industries, Ltd. | Rasagiline formulations of improved content uniformity |
| JP2009521402A (ja) | 2005-11-17 | 2009-06-04 | テバ ファーマシューティカル インダストリーズ リミティド | プロパルギル化アミノインダンの分離のための方法 |
| US7572834B1 (en) | 2005-12-06 | 2009-08-11 | Teva Pharmaceutical Industries, Ltd. | Rasagiline formulations and processes for their preparation |
| EP1991214B1 (en) | 2006-02-21 | 2015-08-05 | Teva Pharmaceutical Industries, Ltd. | Use of rasagiline for the treatment of multiple system atrophy |
| US8946300B2 (en) | 2006-04-03 | 2015-02-03 | Teva Pharmaceutical Industries, Ltd. | Use of rasagilline for the treatment of restless legs syndrome |
| EP1892233A1 (de) | 2006-08-18 | 2008-02-27 | Ratiopharm GmbH | Neue Salze des Wirkstoffs Rasagilin |
| US7547806B2 (en) | 2006-12-14 | 2009-06-16 | Teva Pharmaceutical Industries, Ltd. | Tannate salt of rasagiline |
| ATE528989T1 (de) | 2006-12-14 | 2011-11-15 | Teva Pharma | Kristalline feste rasagilin-base |
| EP1987816A1 (de) | 2007-04-30 | 2008-11-05 | Ratiopharm GmbH | Adsorbate eines Rasagilinsalzes mit einem wasserlöslichen Hilfsstoff |
| AU2008296908B2 (en) | 2007-09-05 | 2014-01-09 | Teva Pharmaceutical Industries, Ltd. | Method of treating glaucoma using rasagiline |
| US8188149B2 (en) | 2007-09-17 | 2012-05-29 | Teva Pharmaceutical Industries, Ltd. | Use of R(+)-N-propargy1-1-aminoindan to treat or prevent hearing loss |
| NZ586025A (en) | 2008-01-11 | 2012-08-31 | Teva Pharma | Rasagiline mesylate tablet coated with a composisiton comprising methacrylic acid - ethyl acrylate copolymer and triethyl citrate |
| WO2009151594A1 (en) | 2008-06-10 | 2009-12-17 | Teva Pharmaceutical Industries, Ltd. | Rasagiline soft gelatin capsules |
| JP2011522892A (ja) * | 2008-06-13 | 2011-08-04 | テバ ファーマシューティカル インダストリーズ リミティド | パーキンソン病緩和のためのラサギリン |
| JP2011525489A (ja) | 2008-06-19 | 2011-09-22 | テバ ファーマシューティカル インダストリーズ リミティド | ラサリジン塩基の精製方法 |
| EP2299992A4 (en) | 2008-06-19 | 2015-10-21 | Teva Pharma | PROCESS FOR THE PREPARATION AND DRYING OF A SOLID RASAGILINE BASE |
| DE102008064061A1 (de) | 2008-12-19 | 2010-06-24 | Ratiopharm Gmbh | Feste Zusammensetzung mit dem Wirkstoff Rasagilin |
| US20100189788A1 (en) | 2009-01-23 | 2010-07-29 | Teva Pharmaceutical Industries, Ltd. | Delayed release rasagiline base formulation |
| HRP20140845T1 (hr) | 2009-07-09 | 2014-11-07 | Ratiopharm Gmbh | Soli rasagilina i farmaceutski pripravci od njih |
| US20110130466A1 (en) | 2009-10-09 | 2011-06-02 | Stefan Lorenzl | Use of rasagiline for the treatment of progressive supranuclear palsy |
| EP2939669A1 (en) | 2009-12-22 | 2015-11-04 | Teva Pharmaceutical Industries, Ltd. | 3-keto-n-propargyl-1-aminoindan |
| RU2013108256A (ru) | 2010-07-27 | 2014-09-10 | Тева Фармасьютикал Индастриз Лтд. | Дисперсии цитрата разагилина |
| CN103188933A (zh) | 2010-10-26 | 2013-07-03 | 泰华制药工业有限公司 | 富集氘的雷沙吉兰 |
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2011
- 2011-07-27 RU RU2013108258/15A patent/RU2587330C2/ru not_active IP Right Cessation
- 2011-07-27 WO PCT/US2011/045574 patent/WO2012015950A1/en not_active Ceased
- 2011-07-27 CA CA2806740A patent/CA2806740A1/en not_active Abandoned
- 2011-07-27 EP EP11813130.9A patent/EP2603212A4/en not_active Withdrawn
- 2011-07-27 US US13/192,019 patent/US8569379B2/en not_active Expired - Fee Related
- 2011-07-27 JP JP2013521949A patent/JP2013533287A/ja not_active Ceased
- 2011-07-27 AU AU2011282720A patent/AU2011282720B2/en not_active Ceased
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2373197C2 (ru) * | 2004-03-30 | 2009-11-20 | Тайсо Фармасьютикал Ко., Лтд. | Пиримидиновые производные, обладающие активностью в отношении мсн |
| WO2009003147A1 (en) * | 2007-06-26 | 2008-12-31 | Parkinson's Institute | Methods and compositions for the treatment of neurological disorders |
Non-Patent Citations (1)
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| САВВАТЕЕВА Д.М. и др. "Диагностика и лечение обонятельной дисфункции у больных острым риносинуситом". Российская ринология, 2010, 3", найдено 26.05.2015, найдено из Интернет: bionorica.ru›?misc/rus/pdf/sinup/lopatin-.... NINKINA NN et al. "Modelling synucleinopathies in genetically modified animals - successes and failures". Mol Biol 2008 Sep-Oct;42(5):840-55, реферат, найдено 26.05.2015, найдено из PubMed PMID:18988533. * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2713786C1 (ru) * | 2019-05-24 | 2020-02-07 | Сергей Геннадиевич Вахрушев | Способ лечения пациентов с обонятельной дисфункцией при атрофическом рините |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2011282720B2 (en) | 2016-12-22 |
| JP2013533287A (ja) | 2013-08-22 |
| EP2603212A4 (en) | 2014-01-08 |
| WO2012015950A1 (en) | 2012-02-02 |
| US20120029087A1 (en) | 2012-02-02 |
| CA2806740A1 (en) | 2012-02-02 |
| RU2013108258A (ru) | 2014-09-10 |
| EP2603212A1 (en) | 2013-06-19 |
| US8569379B2 (en) | 2013-10-29 |
| AU2011282720A1 (en) | 2013-03-14 |
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