RU2539797C2 - Производное гормона роста человека с повышенной стабильностью к протеолитическому разрушению, способ получения такого производного, его применение, способ лечения и фармацевтическая композиция - Google Patents

Производное гормона роста человека с повышенной стабильностью к протеолитическому разрушению, способ получения такого производного, его применение, способ лечения и фармацевтическая композиция Download PDF

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RU2539797C2
RU2539797C2 RU2011133926/10A RU2011133926A RU2539797C2 RU 2539797 C2 RU2539797 C2 RU 2539797C2 RU 2011133926/10 A RU2011133926/10 A RU 2011133926/10A RU 2011133926 A RU2011133926 A RU 2011133926A RU 2539797 C2 RU2539797 C2 RU 2539797C2
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growth hormone
derivative
hgh
seq
hormone compound
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RU2011133926A (ru
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Оле Хвильстед ОЛСЕН
Йенс БРАЙНХОЛЬТ
Кристине Бруун СЬЁДТ
Хелле ДЕМЮТ
Леиф НЁРСКОВ-ЛАУРИТСЕН
Петер ТЮГЕСЕН
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Ново Нордиск Хелс Кеа Аг
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RU2011133926/10A 2009-01-22 2010-01-22 Производное гормона роста человека с повышенной стабильностью к протеолитическому разрушению, способ получения такого производного, его применение, способ лечения и фармацевтическая композиция RU2539797C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP09151108.9 2009-01-22
EP09151108 2009-01-22
US14811909P 2009-01-29 2009-01-29
US61/148,119 2009-01-29
PCT/EP2010/050725 WO2010084173A1 (en) 2009-01-22 2010-01-22 Stable growth hormone compounds

Publications (2)

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RU2011133926A RU2011133926A (ru) 2013-02-27
RU2539797C2 true RU2539797C2 (ru) 2015-01-27

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RU2011133926/10A RU2539797C2 (ru) 2009-01-22 2010-01-22 Производное гормона роста человека с повышенной стабильностью к протеолитическому разрушению, способ получения такого производного, его применение, способ лечения и фармацевтическая композиция

Country Status (14)

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US (1) US8513192B2 (OSRAM)
EP (1) EP2389389B1 (OSRAM)
JP (2) JP5816097B2 (OSRAM)
KR (1) KR20110122100A (OSRAM)
CN (1) CN102292349B (OSRAM)
AU (1) AU2010207725B2 (OSRAM)
CA (1) CA2747825A1 (OSRAM)
ES (1) ES2542202T3 (OSRAM)
IL (1) IL213686A0 (OSRAM)
MX (1) MX2011007736A (OSRAM)
RU (1) RU2539797C2 (OSRAM)
TW (1) TWI504405B (OSRAM)
WO (1) WO2010084173A1 (OSRAM)
ZA (1) ZA201105419B (OSRAM)

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US8841249B2 (en) 2009-08-06 2014-09-23 Novo Nordisk A/S Growth hormones with prolonged in-vivo efficacy
SI2525834T1 (sl) * 2010-01-22 2019-10-30 Novo Nordisk Healthcare Ag Rastni hormoni s podaljšano in vivo učinkovitostjo
AU2011208620B2 (en) * 2010-01-22 2015-04-16 Novo Nordisk Health Care Ag Stable growth hormone compounds
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WO2022133198A1 (en) * 2020-12-18 2022-06-23 The General Hospital Corporation Probiotics compositions and method of using the same to enhance growth and social function in children

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Publication number Publication date
JP2012515748A (ja) 2012-07-12
US20110306548A1 (en) 2011-12-15
JP5816097B2 (ja) 2015-11-18
EP2389389A1 (en) 2011-11-30
EP2389389B1 (en) 2015-04-15
MX2011007736A (es) 2011-09-06
WO2010084173A1 (en) 2010-07-29
US8513192B2 (en) 2013-08-20
CN102292349A (zh) 2011-12-21
CN102292349B (zh) 2016-04-13
CA2747825A1 (en) 2010-07-29
AU2010207725A1 (en) 2011-07-21
TWI504405B (zh) 2015-10-21
KR20110122100A (ko) 2011-11-09
RU2011133926A (ru) 2013-02-27
ZA201105419B (en) 2012-04-25
ES2542202T3 (es) 2015-08-03
IL213686A0 (en) 2011-07-31
AU2010207725B2 (en) 2015-06-11
TW201032819A (en) 2010-09-16
JP2015193636A (ja) 2015-11-05

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Effective date: 20170123