TWI504405B - 穩定的生長激素化合物 - Google Patents

穩定的生長激素化合物 Download PDF

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Publication number
TWI504405B
TWI504405B TW099101707A TW99101707A TWI504405B TW I504405 B TWI504405 B TW I504405B TW 099101707 A TW099101707 A TW 099101707A TW 99101707 A TW99101707 A TW 99101707A TW I504405 B TWI504405 B TW I504405B
Authority
TW
Taiwan
Prior art keywords
growth hormone
hormone compound
seq
hgh
compound according
Prior art date
Application number
TW099101707A
Other languages
English (en)
Chinese (zh)
Other versions
TW201032819A (en
Inventor
Ole Hvilsted Olsen
Jens Breinholt
Helle Demuth
Peter Thygesen
Original Assignee
Novo Nordisk Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk Healthcare Ag filed Critical Novo Nordisk Healthcare Ag
Publication of TW201032819A publication Critical patent/TW201032819A/zh
Application granted granted Critical
Publication of TWI504405B publication Critical patent/TWI504405B/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
TW099101707A 2009-01-22 2010-01-22 穩定的生長激素化合物 TWI504405B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09151108 2009-01-22

Publications (2)

Publication Number Publication Date
TW201032819A TW201032819A (en) 2010-09-16
TWI504405B true TWI504405B (zh) 2015-10-21

Family

ID=40521462

Family Applications (1)

Application Number Title Priority Date Filing Date
TW099101707A TWI504405B (zh) 2009-01-22 2010-01-22 穩定的生長激素化合物

Country Status (14)

Country Link
US (1) US8513192B2 (OSRAM)
EP (1) EP2389389B1 (OSRAM)
JP (2) JP5816097B2 (OSRAM)
KR (1) KR20110122100A (OSRAM)
CN (1) CN102292349B (OSRAM)
AU (1) AU2010207725B2 (OSRAM)
CA (1) CA2747825A1 (OSRAM)
ES (1) ES2542202T3 (OSRAM)
IL (1) IL213686A0 (OSRAM)
MX (1) MX2011007736A (OSRAM)
RU (1) RU2539797C2 (OSRAM)
TW (1) TWI504405B (OSRAM)
WO (1) WO2010084173A1 (OSRAM)
ZA (1) ZA201105419B (OSRAM)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102112157B (zh) 2008-08-06 2013-05-29 诺沃-诺迪斯克保健股份有限公司 具有延长的体内效能的缀合蛋白
EP2389389B1 (en) 2009-01-22 2015-04-15 Novo Nordisk Health Care AG Stable growth hormone compounds
WO2011015649A1 (en) 2009-08-06 2011-02-10 Novo Nordisk Health Care Ag Growth hormones with prolonged in-vivo efficacy
SI2525834T1 (sl) * 2010-01-22 2019-10-30 Novo Nordisk Healthcare Ag Rastni hormoni s podaljšano in vivo učinkovitostjo
JP5980689B2 (ja) * 2010-01-22 2016-08-31 ノヴォ・ノルディスク・ヘルス・ケア・アーゲー 安定な成長ホルモン化合物
CN103269720A (zh) * 2010-07-22 2013-08-28 诺沃—诺迪斯克保健股份有限公司 生长激素缀合物
EP2981282B1 (en) 2013-04-05 2020-11-04 Novo Nordisk Health Care AG Growth hormone compound formulation
EP4262833A4 (en) * 2020-12-18 2024-11-20 The General Hospital Corporation PROBIOTICS COMPOSITIONS AND METHODS OF USE THEREOF TO IMPROVE GROWTH AND SOCIAL FUNCTION IN CHILDREN

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Also Published As

Publication number Publication date
JP5816097B2 (ja) 2015-11-18
WO2010084173A1 (en) 2010-07-29
JP2012515748A (ja) 2012-07-12
US8513192B2 (en) 2013-08-20
ES2542202T3 (es) 2015-08-03
CN102292349A (zh) 2011-12-21
CN102292349B (zh) 2016-04-13
TW201032819A (en) 2010-09-16
US20110306548A1 (en) 2011-12-15
ZA201105419B (en) 2012-04-25
AU2010207725A1 (en) 2011-07-21
CA2747825A1 (en) 2010-07-29
RU2539797C2 (ru) 2015-01-27
AU2010207725B2 (en) 2015-06-11
EP2389389B1 (en) 2015-04-15
MX2011007736A (es) 2011-09-06
RU2011133926A (ru) 2013-02-27
EP2389389A1 (en) 2011-11-30
KR20110122100A (ko) 2011-11-09
JP2015193636A (ja) 2015-11-05
IL213686A0 (en) 2011-07-31

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