RU2505544C2 - Антитела против tenb2, сконструированные с цистеином, и конъюгаты антитело - лекарственное средство - Google Patents
Антитела против tenb2, сконструированные с цистеином, и конъюгаты антитело - лекарственное средство Download PDFInfo
- Publication number
- RU2505544C2 RU2505544C2 RU2010119937/10A RU2010119937A RU2505544C2 RU 2505544 C2 RU2505544 C2 RU 2505544C2 RU 2010119937/10 A RU2010119937/10 A RU 2010119937/10A RU 2010119937 A RU2010119937 A RU 2010119937A RU 2505544 C2 RU2505544 C2 RU 2505544C2
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- Russia
- Prior art keywords
- antibody
- tenb2
- drug
- cysteine
- conjugate
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- 0 CC(*)(*)C(C(*)NC(*)(*)*)=O Chemical compound CC(*)(*)C(C(*)NC(*)(*)*)=O 0.000 description 5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98141107P | 2007-10-19 | 2007-10-19 | |
| US60/981,411 | 2007-10-19 | ||
| PCT/US2008/080102 WO2009052249A1 (en) | 2007-10-19 | 2008-10-16 | Cysteine engineered anti-tenb2 antibodies and antibody drug conjugates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
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| WO2005117986A2 (en) * | 2004-06-01 | 2005-12-15 | Genentech, Inc. | Antibody drug conjugates and methods |
| WO2006034488A2 (en) * | 2004-09-23 | 2006-03-30 | Genentech, Inc. | Cysteine engineered antibodies and conjugates |
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| RU2737727C2 (ru) * | 2013-04-16 | 2020-12-02 | Дженентек, Инк. | Варианты пертузумаба и их аналитическая характеристика |
| RU2728101C2 (ru) * | 2015-09-22 | 2020-07-28 | Байондис Б.В. | Лечение syd985 пациентов с t-dm1 рефрактерным раком |
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