RU2427571C2 - ЗАМЕЩЕННЫЕ ПРОИЗВОДНЫЕ ИМИДАЗОЛИНА, ОБЛАДАЮЩИЕ АФФИНОСТЬЮ К µ-ОПИАТНОМУ РЕЦЕПТОРУ - Google Patents
ЗАМЕЩЕННЫЕ ПРОИЗВОДНЫЕ ИМИДАЗОЛИНА, ОБЛАДАЮЩИЕ АФФИНОСТЬЮ К µ-ОПИАТНОМУ РЕЦЕПТОРУ Download PDFInfo
- Publication number
- RU2427571C2 RU2427571C2 RU2008129377/04A RU2008129377A RU2427571C2 RU 2427571 C2 RU2427571 C2 RU 2427571C2 RU 2008129377/04 A RU2008129377/04 A RU 2008129377/04A RU 2008129377 A RU2008129377 A RU 2008129377A RU 2427571 C2 RU2427571 C2 RU 2427571C2
- Authority
- RU
- Russia
- Prior art keywords
- dihydro
- imidazole
- carboxylic acid
- methyl ester
- acid methyl
- Prior art date
Links
- 0 *C(C(CC1)CCC1=CCC=O)N(*)* Chemical compound *C(C(CC1)CCC1=CCC=O)N(*)* 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005061430.2 | 2005-12-22 | ||
| DE102005061430A DE102005061430A1 (de) | 2005-12-22 | 2005-12-22 | Substituierte Imidazolin-Derivate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2008129377A RU2008129377A (ru) | 2010-03-27 |
| RU2427571C2 true RU2427571C2 (ru) | 2011-08-27 |
Family
ID=37946192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2008129377/04A RU2427571C2 (ru) | 2005-12-22 | 2006-12-19 | ЗАМЕЩЕННЫЕ ПРОИЗВОДНЫЕ ИМИДАЗОЛИНА, ОБЛАДАЮЩИЕ АФФИНОСТЬЮ К µ-ОПИАТНОМУ РЕЦЕПТОРУ |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7728028B2 (https=) |
| EP (1) | EP1963278B1 (https=) |
| JP (1) | JP2009523124A (https=) |
| CN (1) | CN101384557A (https=) |
| AT (1) | ATE449075T1 (https=) |
| AU (1) | AU2006334743B2 (https=) |
| CA (1) | CA2633918A1 (https=) |
| CY (1) | CY1110465T1 (https=) |
| DE (2) | DE102005061430A1 (https=) |
| DK (1) | DK1963278T3 (https=) |
| ES (1) | ES2336833T3 (https=) |
| IL (1) | IL192268A0 (https=) |
| PL (1) | PL1963278T3 (https=) |
| PT (1) | PT1963278E (https=) |
| RU (1) | RU2427571C2 (https=) |
| SI (1) | SI1963278T1 (https=) |
| WO (1) | WO2007079927A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009228647B2 (en) | 2008-03-27 | 2013-07-04 | Grunenthal Gmbh | Substituted spirocyclic cyclohexane derivatives |
| JP5529843B2 (ja) | 2008-03-27 | 2014-06-25 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 置換シクロヘキシルジアミン |
| EP2280941B1 (de) | 2008-03-27 | 2015-05-06 | Grünenthal GmbH | (hetero-)aryl-cyclohexan-derivate |
| ES2375543T3 (es) | 2008-03-27 | 2012-03-01 | Grünenthal GmbH | Derivados de espiro(5.5)undecano. |
| ES2464102T3 (es) | 2008-03-27 | 2014-05-30 | Grünenthal GmbH | Derivados de 4-aminociclohexano sustituidos |
| CN102046591B (zh) | 2008-03-27 | 2014-12-03 | 格吕伦塔尔有限公司 | 羟甲基环己胺 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU329180A1 (ru) * | О. М. Радул, В. И. Гукар С. И. Завь лов | Способ получения илаидазолинон-2-карбоновой--4{5)-кислоты |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5952360A (en) * | 1997-08-28 | 1999-09-14 | Eli Lilly And Company | Method for treating neuropathic pain |
| AU9034798A (en) * | 1997-08-28 | 1999-03-16 | Eli Lilly And Company | Method for treating pain |
| DE10000312A1 (de) * | 2000-01-05 | 2001-07-12 | Gruenenthal Gmbh | Substituierte Aminomethyl-Phenyl-Cyclohexanderivate |
| EP1486490A1 (en) * | 2002-02-28 | 2004-12-15 | Takeda Chemical Industries, Ltd. | Azole compounds |
| US7345078B2 (en) * | 2002-05-31 | 2008-03-18 | The Board Of Trustees Of Michigan State University | NF-κB inhibitors and uses thereof |
| US6878735B2 (en) * | 2002-05-31 | 2005-04-12 | Board Of Trustees Of Michigan State University | Multi-substituted imidazolines and method of use thereof |
| DE102005061429A1 (de) * | 2005-12-22 | 2007-06-28 | Grünenthal GmbH | Substituierte Oxazol-Derivate |
-
2005
- 2005-12-22 DE DE102005061430A patent/DE102005061430A1/de not_active Withdrawn
-
2006
- 2006-12-19 AU AU2006334743A patent/AU2006334743B2/en not_active Ceased
- 2006-12-19 DK DK06841028.1T patent/DK1963278T3/da active
- 2006-12-19 EP EP06841028A patent/EP1963278B1/de not_active Not-in-force
- 2006-12-19 PT PT06841028T patent/PT1963278E/pt unknown
- 2006-12-19 RU RU2008129377/04A patent/RU2427571C2/ru not_active IP Right Cessation
- 2006-12-19 CA CA002633918A patent/CA2633918A1/en not_active Abandoned
- 2006-12-19 CN CNA2006800532577A patent/CN101384557A/zh active Pending
- 2006-12-19 ES ES06841028T patent/ES2336833T3/es active Active
- 2006-12-19 SI SI200630546T patent/SI1963278T1/sl unknown
- 2006-12-19 WO PCT/EP2006/012221 patent/WO2007079927A1/de not_active Ceased
- 2006-12-19 DE DE502006005426T patent/DE502006005426D1/de active Active
- 2006-12-19 PL PL06841028T patent/PL1963278T3/pl unknown
- 2006-12-19 JP JP2008546224A patent/JP2009523124A/ja not_active Ceased
- 2006-12-19 AT AT06841028T patent/ATE449075T1/de active
-
2008
- 2008-06-18 IL IL192268A patent/IL192268A0/en unknown
- 2008-06-20 US US12/143,566 patent/US7728028B2/en not_active Expired - Fee Related
-
2010
- 2010-02-02 CY CY20101100093T patent/CY1110465T1/el unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU329180A1 (ru) * | О. М. Радул, В. И. Гукар С. И. Завь лов | Способ получения илаидазолинон-2-карбоновой--4{5)-кислоты |
Also Published As
| Publication number | Publication date |
|---|---|
| US20090048323A1 (en) | 2009-02-19 |
| IL192268A0 (en) | 2008-12-29 |
| DE502006005426D1 (de) | 2009-12-31 |
| AU2006334743B2 (en) | 2011-07-07 |
| AU2006334743A1 (en) | 2007-07-19 |
| JP2009523124A (ja) | 2009-06-18 |
| US7728028B2 (en) | 2010-06-01 |
| CY1110465T1 (el) | 2015-04-29 |
| WO2007079927A1 (de) | 2007-07-19 |
| PT1963278E (pt) | 2009-12-16 |
| EP1963278B1 (de) | 2009-11-18 |
| CN101384557A (zh) | 2009-03-11 |
| ES2336833T3 (es) | 2010-04-16 |
| EP1963278A1 (de) | 2008-09-03 |
| RU2008129377A (ru) | 2010-03-27 |
| ATE449075T1 (de) | 2009-12-15 |
| DE102005061430A1 (de) | 2007-07-05 |
| DK1963278T3 (da) | 2010-03-29 |
| PL1963278T3 (pl) | 2010-04-30 |
| HK1122019A1 (zh) | 2009-05-08 |
| CA2633918A1 (en) | 2007-07-19 |
| SI1963278T1 (sl) | 2010-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20121220 |