RU2399628C2 - Производные циклоспорина, замещенные 3-эфиром и 3-тиоэфиром, для лечения и профилактики инфекционного гепатита с - Google Patents

Производные циклоспорина, замещенные 3-эфиром и 3-тиоэфиром, для лечения и профилактики инфекционного гепатита с Download PDF

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RU2399628C2
RU2399628C2 RU2007116119/04A RU2007116119A RU2399628C2 RU 2399628 C2 RU2399628 C2 RU 2399628C2 RU 2007116119/04 A RU2007116119/04 A RU 2007116119/04A RU 2007116119 A RU2007116119 A RU 2007116119A RU 2399628 C2 RU2399628 C2 RU 2399628C2
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carbon atoms
cyclosporin
different
same
branched chain
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RU2007116119/04A
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RU2007116119A (ru
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Ханс Георг ФЛИРИ (GB)
Ханс Георг ФЛИРИ
Дэвид Ренвик ХОУК (US)
Дэвид Ренвик ХОУК
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Скайнексис, Инк.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • C07K7/645Cyclosporins; Related peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RU2007116119/04A 2004-10-01 2005-09-30 Производные циклоспорина, замещенные 3-эфиром и 3-тиоэфиром, для лечения и профилактики инфекционного гепатита с RU2399628C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US61515204P 2004-10-01 2004-10-01
US60/615,152 2004-10-01
US70762605P 2005-08-11 2005-08-11
US60/707,626 2005-08-11

Publications (2)

Publication Number Publication Date
RU2007116119A RU2007116119A (ru) 2008-11-10
RU2399628C2 true RU2399628C2 (ru) 2010-09-20

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RU2007116119/04A RU2399628C2 (ru) 2004-10-01 2005-09-30 Производные циклоспорина, замещенные 3-эфиром и 3-тиоэфиром, для лечения и профилактики инфекционного гепатита с

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US (2) US20100167996A1 (https=)
EP (1) EP1802650B1 (https=)
JP (2) JP5139065B2 (https=)
KR (1) KR101309409B1 (https=)
CN (1) CN101773661B (https=)
AT (1) ATE530561T1 (https=)
AU (1) AU2005292162B2 (https=)
BR (1) BRPI0516737A (https=)
CA (1) CA2583494C (https=)
DK (1) DK1802650T3 (https=)
ES (1) ES2373450T3 (https=)
IL (1) IL182315A (https=)
MX (1) MX2007003538A (https=)
NZ (1) NZ554514A (https=)
PL (1) PL1802650T3 (https=)
PT (1) PT1802650E (https=)
RU (1) RU2399628C2 (https=)
SI (1) SI1802650T1 (https=)
WO (1) WO2006039668A2 (https=)

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RU2448690C1 (ru) * 2011-03-15 2012-04-27 Открытое акционерное общество "Биосинтез" Твердая лекарственная форма пролонгированного действия нестероидного противовоспалительного средства кетопрофен, способ получения
RU2492181C2 (ru) * 2009-01-30 2013-09-10 Энанта Фармасьютикалс, Инк. Аналоги циклоспорина для предупреждения или лечения инфекции гепатита с

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KR101273681B1 (ko) 2005-10-26 2013-06-25 아스텔라스세이야쿠 가부시키가이샤 신규 시클릭 펩티드 화합물
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EA201390532A1 (ru) 2010-10-08 2013-09-30 Новартис Аг Композиции сульфамидых ингибиторов ns3, содержащие витамин е
US9890198B2 (en) 2010-12-03 2018-02-13 S&T Global Inc. Cyclosporin derivatives and uses thereof
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Cited By (2)

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Publication number Priority date Publication date Assignee Title
RU2492181C2 (ru) * 2009-01-30 2013-09-10 Энанта Фармасьютикалс, Инк. Аналоги циклоспорина для предупреждения или лечения инфекции гепатита с
RU2448690C1 (ru) * 2011-03-15 2012-04-27 Открытое акционерное общество "Биосинтез" Твердая лекарственная форма пролонгированного действия нестероидного противовоспалительного средства кетопрофен, способ получения

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EP1802650A4 (en) 2008-08-20
KR101309409B1 (ko) 2013-09-23
JP2012167113A (ja) 2012-09-06
EP1802650B1 (en) 2011-10-26
ES2373450T3 (es) 2012-02-03
WO2006039668A2 (en) 2006-04-13
MX2007003538A (es) 2008-01-16
WO2006039668B1 (en) 2007-05-31
CA2583494A1 (en) 2006-04-13
WO2006039668A3 (en) 2007-04-19
RU2007116119A (ru) 2008-11-10
KR20070073841A (ko) 2007-07-10
PT1802650E (pt) 2011-12-30
IL182315A0 (en) 2007-07-24
US20120264679A1 (en) 2012-10-18
IL182315A (en) 2013-08-29
DK1802650T3 (da) 2012-02-06
PL1802650T3 (pl) 2012-04-30
BRPI0516737A (pt) 2008-04-29
CN101773661A (zh) 2010-07-14
HK1108703A1 (en) 2008-05-16
NZ554514A (en) 2010-10-29
CA2583494C (en) 2014-01-21
EP1802650A2 (en) 2007-07-04
JP5139065B2 (ja) 2013-02-06
CN101773661B (zh) 2013-09-25
ATE530561T1 (de) 2011-11-15
AU2005292162B2 (en) 2011-11-10
AU2005292162A1 (en) 2006-04-13
US20100167996A1 (en) 2010-07-01
JP2008514732A (ja) 2008-05-08
SI1802650T1 (sl) 2012-03-30

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