RU2372788C2 - Пробиотическая стимулирующая здоровье или производительность кормовая добавка или добавка к питьевой воде, а также ее применение - Google Patents
Пробиотическая стимулирующая здоровье или производительность кормовая добавка или добавка к питьевой воде, а также ее применение Download PDFInfo
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- RU2372788C2 RU2372788C2 RU2008101448/13A RU2008101448A RU2372788C2 RU 2372788 C2 RU2372788 C2 RU 2372788C2 RU 2008101448/13 A RU2008101448/13 A RU 2008101448/13A RU 2008101448 A RU2008101448 A RU 2008101448A RU 2372788 C2 RU2372788 C2 RU 2372788C2
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Landscapes
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- Coloring Foods And Improving Nutritive Qualities (AREA)
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Applications Claiming Priority (2)
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| ATA999/2005 | 2005-06-14 | ||
| AT0099905A AT501919B1 (de) | 2005-06-14 | 2005-06-14 | Probiotischer, gesundheits- bzw. leistungsfördernder futtermittel- und/oder trinkwasserzusatz für tiere sowie seine verwendung |
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| RU2008101448A RU2008101448A (ru) | 2009-07-20 |
| RU2372788C2 true RU2372788C2 (ru) | 2009-11-20 |
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| EP (1) | EP1890553B1 (enExample) |
| JP (1) | JP4846795B2 (enExample) |
| CN (1) | CN101262779B (enExample) |
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| DK (1) | DK1890553T3 (enExample) |
| MX (1) | MX2007015650A (enExample) |
| RU (1) | RU2372788C2 (enExample) |
| WO (1) | WO2006133472A1 (enExample) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2410105C1 (ru) * | 2009-12-29 | 2011-01-27 | Федеральное Государственное Образовательное Учреждение Высшего Профессионального Образования "Саратовский Государственный Аграрный Университет Имени Н.И. Вавилова" | Препарат для лечения и профилактики дисбактериальных состояний кишечника у птиц |
| RU2422041C1 (ru) * | 2010-01-25 | 2011-06-27 | Владислав Николаевич Ласкавый | Добавка к питьевой воде для кур и способ ее применения |
| RU2493725C1 (ru) * | 2012-03-22 | 2013-09-27 | Сергей Иванович Першин | Композиция ингредиентов для кормового продукта сельскохозяйственных животных и птиц |
| RU2533154C1 (ru) * | 2013-07-17 | 2014-11-20 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" | Комплексная пробиотическая кормовая добавка для увеличения убойной массы при выращивании цыплят-бройлеров |
| RU2665815C2 (ru) * | 2012-09-25 | 2018-09-04 | Акилон Киль, Сл | Композиция пробиотиков и пребиотиков |
| RU2721127C1 (ru) * | 2016-08-09 | 2020-05-18 | СиДжей ЧеилДжеданг Корпорейшн | Lactobacillus salivarius cjls1511, композиция кормовой добавки для животных, содержащая указанную бактерию или ее мертвые клетки, и способ получения указанных мертвых клеток |
| RU2787241C2 (ru) * | 2022-05-25 | 2022-12-30 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Оренбургский государственный аграрный университет" | Способ повышения продуктивности цыплят-бройлеров |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7029702B2 (en) | 1998-07-07 | 2006-04-18 | Ritter Natural Sciences Llc | Method for increasing lactose tolerance in mammals exhibiting lactose intolerance |
| US20050158294A1 (en) | 2003-12-19 | 2005-07-21 | The Procter & Gamble Company | Canine probiotic Bifidobacteria pseudolongum |
| US8877178B2 (en) | 2003-12-19 | 2014-11-04 | The Iams Company | Methods of use of probiotic bifidobacteria for companion animals |
| US20080126195A1 (en) | 2004-07-22 | 2008-05-29 | Ritter Andrew J | Methods and Compositions for Treating Lactose Intolerance |
| JP4938005B2 (ja) | 2005-05-31 | 2012-05-23 | ザ・アイムス・カンパニー | ネコ科動物プロバイオティックであるラクトバシラス |
| BRPI0611492B1 (pt) | 2005-05-31 | 2021-10-13 | Mars, Incorporated | Bifidobactéria probiótica felina |
| CN101172118A (zh) * | 2006-07-26 | 2008-05-07 | 美国医迈科技有限公司 | 作为抗传染病替代药物的益生微生物 |
| CA2673465A1 (en) | 2007-02-01 | 2008-08-07 | The Iams Company | Method for decreasing inflammation and stress in a mammal |
| JP4903680B2 (ja) * | 2007-12-13 | 2012-03-28 | 株式会社プロバイオインターナショナル | パンの製造方法 |
| JP2009242275A (ja) * | 2008-03-31 | 2009-10-22 | Kagaku Shiryo Kenkyusho:Kk | 生菌剤 |
| CN102159224A (zh) | 2008-05-23 | 2011-08-17 | 爱尔伯股份公司 | 益生的饲料添加剂和/或饮用水添加剂及其用途 |
| US9771199B2 (en) | 2008-07-07 | 2017-09-26 | Mars, Incorporated | Probiotic supplement, process for making, and packaging |
| US9232813B2 (en) | 2008-07-07 | 2016-01-12 | The Iams Company | Probiotic supplement, process for making, and packaging |
| WO2010098822A1 (en) | 2009-02-24 | 2010-09-02 | Ritter Pharmaceuticals, Inc. | Prebiotic formulations and methods of use |
| JP2010265194A (ja) * | 2009-05-13 | 2010-11-25 | Sankai Kasei Kk | 動物の病原菌排除方法 |
| US10104903B2 (en) | 2009-07-31 | 2018-10-23 | Mars, Incorporated | Animal food and its appearance |
| CN101664058B (zh) * | 2009-10-16 | 2013-01-02 | 内蒙古蒙牛乳业（集团）股份有限公司 | 一种悬浮颗粒饮用型酸奶及其制备方法 |
| WO2011060474A1 (de) * | 2009-11-20 | 2011-05-26 | Erber Aktiengesellschaft | Verfahren zur herstellung eines futtermittelzusatzes sowie futtermittelzusatz |
| WO2011092261A1 (en) * | 2010-01-28 | 2011-08-04 | Ab-Biotics S.A. | Probiotic composition for use in the treatment of bowel inflammation |
| US20130058898A1 (en) | 2010-03-10 | 2013-03-07 | Kaneka Corporation | Lactic acid bacterium-containing preparation |
| EP3202406A1 (en) | 2010-04-28 | 2017-08-09 | Ritter Pharmaceuticals, Inc. | Prebiotic formulations and methods of use |
| KR101201337B1 (ko) | 2010-07-22 | 2012-11-15 | 대한민국 | 신규한 락토바실러스속 유산균 복합 균주를 포함하는 사료첨가제 |
| GB201021399D0 (en) | 2010-12-16 | 2011-01-26 | Genetic Analysis As | Oligonucleotide probe set and methods of microbiota profiling |
| CN102191192B (zh) * | 2010-12-21 | 2012-09-26 | 北京博锦元生物科技有限公司 | 一种动物双歧杆菌及其应用方法 |
| JP2012180304A (ja) * | 2011-03-01 | 2012-09-20 | Biseibutsu Kagaku Kenkyusho:Kk | 鶏のカンピロバクター感染を制御するための飲料 |
| US9387236B2 (en) * | 2011-06-10 | 2016-07-12 | Prothera Inc. | Pharmaceutical compositions containing protease and methods for the treatment of lysosomal storage diseases |
| US9113653B2 (en) | 2011-08-19 | 2015-08-25 | Steven J Maranz | Methods of administering probiotic organisms that synthesize carotenoid compounds in situ to enhance human health and nutrition |
| US9474303B2 (en) | 2011-09-22 | 2016-10-25 | R.J. Reynolds Tobacco Company | Translucent smokeless tobacco product |
| CN102511662A (zh) * | 2012-01-05 | 2012-06-27 | 上海创博生态工程有限公司 | 一种复合益生菌微生物饲料添加剂、制备方法及应用 |
| US20130269719A1 (en) | 2012-04-11 | 2013-10-17 | R.J. Reynolds Tobacco Company | Method for treating plants with probiotics |
| JP6290080B2 (ja) | 2012-07-31 | 2018-03-07 | 株式会社カネカ | 新規乳酸菌 |
| CN103404704B (zh) * | 2013-07-09 | 2015-01-07 | 天津市星河系科技有限公司 | 一种饲料添加剂及其制备方法 |
| US11503853B2 (en) | 2013-09-09 | 2022-11-22 | R.J. Reynolds Tobacco Company | Smokeless tobacco composition incorporating a botanical material |
| AU2015296538B2 (en) | 2014-07-29 | 2019-01-31 | BiOWiSH Technologies, Inc. | Animal feed compositions and feed additives |
| US20160128337A1 (en) * | 2014-11-07 | 2016-05-12 | BiOWiSH Technologies, Inc. | Antibacterial compositions and methods of use |
| EP3229595B1 (en) | 2014-12-12 | 2021-02-03 | The Regents of the University of California | Reduction of milk glycans and their degradation products in the neonate gut |
| WO2016100881A1 (en) * | 2014-12-18 | 2016-06-23 | Microbios, Inc. | Prebiotic and bacterial-based probiotic pathogen inhibitor |
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| JP6127261B2 (ja) * | 2015-01-28 | 2017-05-17 | 株式会社鎌田工業 | 鳥類飼料 |
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| ES2698384T3 (es) * | 2016-02-10 | 2019-02-04 | Fundacion Tecnalia Res & Innovation | Microcápsulas probióticas multicapa |
| CN106721247B (zh) * | 2016-11-10 | 2020-07-14 | 南京工业大学 | 一种可促进断奶猪仔肠道发育的饲料添加剂 |
| RU2656064C1 (ru) * | 2017-05-23 | 2018-05-30 | Федеральное государственное бюджетное научное учреждение "Краснодарский научный центр по зоотехнии и ветеринарии" | Способ применения пробиотической кормовой добавки "лактовит-жк" при выращивании цыплят-бройлеров |
| US11833179B2 (en) * | 2017-10-13 | 2023-12-05 | Stellenbosch University | Probiotic composition |
| CA3085456A1 (en) * | 2017-12-14 | 2019-06-20 | Pure Cultures 2020, Inc. | Probiotics and fermentation metabolites for the prevention and treatment of disease conditions in animals |
| RU2689680C1 (ru) * | 2018-07-11 | 2019-05-28 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный аграрный университет имени И.Т. Трубилина" | Способ производства пробиотической добавки |
| US20220330576A1 (en) * | 2019-08-16 | 2022-10-20 | Dupont Nutrition Biosciences Aps | Compositions for gut health |
| AU2021220800A1 (en) | 2020-02-10 | 2022-07-07 | Native Microbials, Inc. | Microbial compositions and methods of use for canine enteropathy and dysbiosis |
| FR3112557B1 (fr) * | 2020-07-20 | 2025-12-05 | Lesaffre & Cie | Combinaison de souches de lactobacilles et son utilisation en sante animale |
| BE1028802B1 (fr) | 2020-11-16 | 2022-06-14 | Le Centre Wallon De Rech Agronomiques | Développement d'une composition symbiotique comme un additif d'alimentation pour les porcelets ou les truies gestantes pour moduler le microbiote intestinal des porcelets au temps du sevrage |
| CN112715767A (zh) * | 2020-12-27 | 2021-04-30 | 福建傲农生物科技集团股份有限公司 | 一种改善早期断奶仔猪肠道功能的饲料添加剂及其应用 |
| WO2022169933A2 (en) * | 2021-02-03 | 2022-08-11 | Dupont Nutrition Biosciences Aps | Compositions for gut health |
| GB202204335D0 (en) * | 2022-03-28 | 2022-05-11 | Hel1X Ltd | Non-antibiotic antimicrobial compositions |
| EP4585055A1 (en) | 2024-01-12 | 2025-07-16 | Nicoventures Trading Limited | Oral product with probiotic component |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE20202562U1 (de) * | 2002-02-19 | 2002-05-23 | Orthomol pharmazeutische Vertriebs GmbH, 40764 Langenfeld | Mikronährstoffkombinationsprodukt mit Pro- und Prebiotika |
| RU2229827C2 (ru) * | 2002-04-30 | 2004-06-10 | Государственное научное учреждение Всероссийский научно-исследовательский институт физиологии, биохимии и питания сельскохозяйственных животных | Способ повышения продуктивности сельскохозяйственных животных и улучшения качества продукции |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3549880B2 (ja) * | 1991-10-31 | 2004-08-04 | ジラ・インコーポレーテッド | 生物学的染料組成物、調製方法および上皮癌描写への使用方法 |
| US5951977A (en) | 1997-10-14 | 1999-09-14 | The United States Of America, As Represented By The Secretary Of Agriculture | Competitive exclusion culture for swine |
| KR100387245B1 (ko) * | 1997-10-17 | 2003-08-19 | 일양약품주식회사 | 유산균의안정화를위한미세장용성코팅과립 |
| CA2334370A1 (en) * | 1998-06-05 | 1999-12-16 | Nobuyuki Suzuki | Lactic acid bacterium-containing compositions, drugs and foods |
| JP2002065206A (ja) * | 2000-09-01 | 2002-03-05 | Toyo Shinyaku:Kk | 免疫賦活食品 |
| DE10105347A1 (de) * | 2001-02-05 | 2002-08-22 | Nutrinova Gmbh | Sorbinsäurepräparat enthaltend Probiotika als Futtermittelzusatz in der Nutztieraufzucht |
| US8263146B2 (en) * | 2001-02-19 | 2012-09-11 | Nestec S.A. | Consumable product containing probiotics |
| JP2002306125A (ja) * | 2001-04-12 | 2002-10-22 | Morinaga Milk Ind Co Ltd | プロバイオティクスを含有する包装容器入り乳幼児用栄養組成物 |
| WO2003054168A2 (en) | 2001-12-20 | 2003-07-03 | Board Of Trustees Of The University Of Arkansas | Defined competitive exclusion cultures for food borne pathogens |
| DE10206995B4 (de) * | 2002-02-19 | 2014-01-02 | Orthomol Pharmazeutische Vertriebs Gmbh | Mikronährstoffkombinationsprodukt mit Pro- und Prebiotika |
| CN1301708C (zh) * | 2002-02-21 | 2007-02-28 | 雀巢产品有限公司 | 用于皮肤光保护的人用口服组合物 |
| EP1344458A1 (en) * | 2002-03-12 | 2003-09-17 | Société des Produits Nestlé S.A. | Probiotic delivery system |
| EP1554371A2 (en) * | 2002-09-26 | 2005-07-20 | Probiohealth, LLC | Prebiotic and preservative uses of oil-emulsified probiotic encapsulations |
| AT413191B (de) * | 2002-10-11 | 2005-12-15 | Erber Ag | Futtermittel- und/oder trinkwasserzusatz für nutztiere |
| JP2004250337A (ja) * | 2003-02-18 | 2004-09-09 | Sunstar Inc | アレルギー疾患改善用製剤 |
-
2005
- 2005-06-14 AT AT0099905A patent/AT501919B1/de not_active IP Right Cessation
-
2006
- 2006-06-14 MX MX2007015650A patent/MX2007015650A/es active IP Right Grant
- 2006-06-14 CA CA2610585A patent/CA2610585C/en active Active
- 2006-06-14 DK DK06752579T patent/DK1890553T3/da active
- 2006-06-14 CN CN2006800280519A patent/CN101262779B/zh active Active
- 2006-06-14 AU AU2006257751A patent/AU2006257751B9/en active Active
- 2006-06-14 WO PCT/AT2006/000243 patent/WO2006133472A1/de not_active Ceased
- 2006-06-14 JP JP2008516061A patent/JP4846795B2/ja active Active
- 2006-06-14 EP EP06752579A patent/EP1890553B1/de active Active
- 2006-06-14 US US11/922,136 patent/US8101170B2/en active Active
- 2006-06-14 RU RU2008101448/13A patent/RU2372788C2/ru active
- 2006-06-14 BR BRPI0612298-1A patent/BRPI0612298B1/pt active IP Right Grant
- 2006-06-14 DE DE502006001458T patent/DE502006001458D1/de active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE20202562U1 (de) * | 2002-02-19 | 2002-05-23 | Orthomol pharmazeutische Vertriebs GmbH, 40764 Langenfeld | Mikronährstoffkombinationsprodukt mit Pro- und Prebiotika |
| RU2229827C2 (ru) * | 2002-04-30 | 2004-06-10 | Государственное научное учреждение Всероссийский научно-исследовательский институт физиологии, биохимии и питания сельскохозяйственных животных | Способ повышения продуктивности сельскохозяйственных животных и улучшения качества продукции |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2410105C1 (ru) * | 2009-12-29 | 2011-01-27 | Федеральное Государственное Образовательное Учреждение Высшего Профессионального Образования "Саратовский Государственный Аграрный Университет Имени Н.И. Вавилова" | Препарат для лечения и профилактики дисбактериальных состояний кишечника у птиц |
| RU2422041C1 (ru) * | 2010-01-25 | 2011-06-27 | Владислав Николаевич Ласкавый | Добавка к питьевой воде для кур и способ ее применения |
| WO2011090401A1 (ru) * | 2010-01-25 | 2011-07-28 | Laskavy Vladislav Nikolaevich | Добавка к питьевой воде для кур и способ её применения |
| RU2493725C1 (ru) * | 2012-03-22 | 2013-09-27 | Сергей Иванович Першин | Композиция ингредиентов для кормового продукта сельскохозяйственных животных и птиц |
| RU2665815C2 (ru) * | 2012-09-25 | 2018-09-04 | Акилон Киль, Сл | Композиция пробиотиков и пребиотиков |
| US10265350B2 (en) | 2012-09-25 | 2019-04-23 | Universidad De Leon | Probiotic and prebiotic compositions |
| RU2533154C1 (ru) * | 2013-07-17 | 2014-11-20 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" | Комплексная пробиотическая кормовая добавка для увеличения убойной массы при выращивании цыплят-бройлеров |
| RU2721127C1 (ru) * | 2016-08-09 | 2020-05-18 | СиДжей ЧеилДжеданг Корпорейшн | Lactobacillus salivarius cjls1511, композиция кормовой добавки для животных, содержащая указанную бактерию или ее мертвые клетки, и способ получения указанных мертвых клеток |
| US11382940B2 (en) | 2016-08-09 | 2022-07-12 | Cj Cheiljedang Corporation | Lactobacillus salivarius CJLS1511, animal feed additive composition comprising same bacterium or dead cells thereof, and method for producing same dead cells |
| RU2787241C2 (ru) * | 2022-05-25 | 2022-12-30 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Оренбургский государственный аграрный университет" | Способ повышения продуктивности цыплят-бройлеров |
| RU2823282C1 (ru) * | 2024-01-23 | 2024-07-22 | федеральное государственное бюджетное образовательное учреждение высшего образования "Казанская государственная академия ветеринарной медицины имени Н.Э. Баумана" | Кормовая добавка для цыплят-бройлеров |
| RU2831175C1 (ru) * | 2024-07-23 | 2024-12-02 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Оренбургский государственный аграрный университет" | Способ повышения продуктивности цыплят-бройлеров |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1890553B1 (de) | 2008-08-27 |
| CN101262779B (zh) | 2011-04-13 |
| US8101170B2 (en) | 2012-01-24 |
| US20100196323A1 (en) | 2010-08-05 |
| RU2008101448A (ru) | 2009-07-20 |
| DE502006001458D1 (de) | 2008-10-09 |
| BRPI0612298B1 (pt) | 2019-05-21 |
| WO2006133472A1 (de) | 2006-12-21 |
| MX2007015650A (es) | 2008-02-19 |
| AU2006257751A1 (en) | 2006-12-21 |
| CN101262779A (zh) | 2008-09-10 |
| AU2006257751B2 (en) | 2011-03-31 |
| AT501919B1 (de) | 2008-09-15 |
| CA2610585A1 (en) | 2006-12-21 |
| AU2006257751B9 (en) | 2011-04-07 |
| BRPI0612298A2 (pt) | 2010-11-03 |
| JP4846795B2 (ja) | 2011-12-28 |
| DK1890553T3 (da) | 2008-12-15 |
| JP2008543290A (ja) | 2008-12-04 |
| AT501919A1 (de) | 2006-12-15 |
| BRPI0612298A8 (pt) | 2017-12-05 |
| EP1890553A1 (de) | 2008-02-27 |
| CA2610585C (en) | 2013-08-27 |
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