RU2353353C2 - Композиция антагониста vegf и антипролиферативного средства - Google Patents
Композиция антагониста vegf и антипролиферативного средства Download PDFInfo
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- RU2353353C2 RU2353353C2 RU2006105496/15A RU2006105496A RU2353353C2 RU 2353353 C2 RU2353353 C2 RU 2353353C2 RU 2006105496/15 A RU2006105496/15 A RU 2006105496/15A RU 2006105496 A RU2006105496 A RU 2006105496A RU 2353353 C2 RU2353353 C2 RU 2353353C2
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- Prior art keywords
- vegf
- agent
- fcδc1
- antiproliferative agent
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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| Application Number | Priority Date | Filing Date | Title |
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| US49000203P | 2003-07-25 | 2003-07-25 | |
| US60/490,002 | 2003-07-25 | ||
| US49397103P | 2003-08-08 | 2003-08-08 | |
| US60/493,971 | 2003-08-08 |
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| RU2006105496A RU2006105496A (ru) | 2006-06-10 |
| RU2353353C2 true RU2353353C2 (ru) | 2009-04-27 |
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| RU2006105496/15A RU2353353C2 (ru) | 2003-07-25 | 2004-07-23 | Композиция антагониста vegf и антипролиферативного средства |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2597973C2 (ru) * | 2010-03-26 | 2016-09-20 | Ф. Хоффманн-Ля Рош Аг | Биспецифические двухвалентные антитела анти-vegf/анти-ang-2 |
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| US9321832B2 (en) * | 2002-06-28 | 2016-04-26 | Domantis Limited | Ligand |
| AU2003244817B2 (en) * | 2002-06-28 | 2010-08-26 | Domantis Limited | Antigen-binding immunoglobulin single variable domains and dual-specific constructs |
| AU2003290330A1 (en) * | 2002-12-27 | 2004-07-22 | Domantis Limited | Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand |
| US7354578B2 (en) * | 2003-06-06 | 2008-04-08 | Regeneron Pharmaceuticals, Inc. | Method of tumor regression with VEGF inhibitors |
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| AU2006213856B2 (en) * | 2005-02-11 | 2011-03-17 | Regeneron Pharmaceuticals, Inc. | Therapeutic combination of a VEGF antagonist (VEGF trap) and an anti-hypertensive agent |
| CA2598239C (en) * | 2005-02-18 | 2019-10-29 | Abraxis Bioscience, Inc. | Nanoparticulate formulations of taxanes and carrier proteins for use in combination chemotherapy |
| US20070166388A1 (en) * | 2005-02-18 | 2007-07-19 | Desai Neil P | Combinations and modes of administration of therapeutic agents and combination therapy |
| US8735394B2 (en) * | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
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| FR2895258B1 (fr) * | 2005-12-22 | 2008-03-21 | Aventis Pharma Sa | Combinaison comprenant de la combretastatine et des agents anticancereux |
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| WO2000075319A1 (en) * | 1999-06-08 | 2000-12-14 | Regeneron Pharmaceuticals, Inc. | Modified chimeric polypeptides with improved pharmacokinetic properties |
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| US6811779B2 (en) * | 1994-02-10 | 2004-11-02 | Imclone Systems Incorporated | Methods for reducing tumor growth with VEGF receptor antibody combined with radiation and chemotherapy |
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| US7354578B2 (en) * | 2003-06-06 | 2008-04-08 | Regeneron Pharmaceuticals, Inc. | Method of tumor regression with VEGF inhibitors |
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2004
- 2004-07-21 AR ARP040102585A patent/AR046510A1/es unknown
- 2004-07-23 KR KR1020067000521A patent/KR101175990B1/ko not_active Expired - Lifetime
- 2004-07-23 BR BRPI0412798-6A patent/BRPI0412798A/pt not_active Application Discontinuation
- 2004-07-23 MY MYPI20042968A patent/MY149169A/en unknown
- 2004-07-23 CA CA2529742A patent/CA2529742C/en not_active Expired - Lifetime
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- 2004-07-23 MX MXPA05013642A patent/MXPA05013642A/es not_active Application Discontinuation
- 2004-07-23 EP EP04779050A patent/EP1648428A2/en not_active Withdrawn
- 2004-07-23 WO PCT/US2004/023815 patent/WO2005011734A2/en not_active Ceased
- 2004-07-23 RU RU2006105496/15A patent/RU2353353C2/ru active
- 2004-07-23 TW TW093121978A patent/TWI351953B/zh not_active IP Right Cessation
- 2004-07-23 JP JP2006521281A patent/JP5355856B2/ja not_active Expired - Lifetime
- 2004-07-23 AU AU2004261165A patent/AU2004261165C1/en not_active Expired
- 2004-07-23 US US10/897,802 patent/US7354579B2/en not_active Expired - Lifetime
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6342219B1 (en) * | 1999-04-28 | 2002-01-29 | Board Of Regents, The University Of Texas System | Antibody compositions for selectively inhibiting VEGF |
| WO2000075319A1 (en) * | 1999-06-08 | 2000-12-14 | Regeneron Pharmaceuticals, Inc. | Modified chimeric polypeptides with improved pharmacokinetic properties |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2597973C2 (ru) * | 2010-03-26 | 2016-09-20 | Ф. Хоффманн-Ля Рош Аг | Биспецифические двухвалентные антитела анти-vegf/анти-ang-2 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007500131A (ja) | 2007-01-11 |
| JP5355856B2 (ja) | 2013-11-27 |
| MXPA05013642A (es) | 2006-03-10 |
| UY28438A1 (es) | 2004-11-08 |
| IL172406A (en) | 2016-04-21 |
| NZ544570A (en) | 2008-08-29 |
| WO2005011734A2 (en) | 2005-02-10 |
| US7354579B2 (en) | 2008-04-08 |
| CA2529742C (en) | 2012-09-18 |
| AR046510A1 (es) | 2005-12-14 |
| RU2006105496A (ru) | 2006-06-10 |
| BRPI0412798A (pt) | 2006-09-26 |
| EP1648428A2 (en) | 2006-04-26 |
| MY149169A (en) | 2013-07-31 |
| AU2004261165C1 (en) | 2009-12-17 |
| AU2004261165B2 (en) | 2009-07-16 |
| AU2004261165A1 (en) | 2005-02-10 |
| NO20060924L (no) | 2006-04-25 |
| CA2529742A1 (en) | 2005-02-10 |
| TWI351953B (en) | 2011-11-11 |
| WO2005011734A3 (en) | 2005-04-14 |
| US20050032699A1 (en) | 2005-02-10 |
| KR101175990B1 (ko) | 2012-08-23 |
| TW200524589A (en) | 2005-08-01 |
| IL172406A0 (en) | 2006-04-10 |
| KR20060028654A (ko) | 2006-03-30 |
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