RU2298416C2 - Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi - Google Patents

Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi Download PDF

Info

Publication number
RU2298416C2
RU2298416C2 RU2004105031/15A RU2004105031A RU2298416C2 RU 2298416 C2 RU2298416 C2 RU 2298416C2 RU 2004105031/15 A RU2004105031/15 A RU 2004105031/15A RU 2004105031 A RU2004105031 A RU 2004105031A RU 2298416 C2 RU2298416 C2 RU 2298416C2
Authority
RU
Russia
Prior art keywords
factor
factor vii
vii
polypeptide
related polypeptide
Prior art date
Application number
RU2004105031/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2004105031A (ru
Inventor
Расмус РЕЙКЕР (DK)
Расмус РЕЙКЕР
Original Assignee
Ново Нордиск Хелт Кэр Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ново Нордиск Хелт Кэр Аг filed Critical Ново Нордиск Хелт Кэр Аг
Publication of RU2004105031A publication Critical patent/RU2004105031A/ru
Application granted granted Critical
Publication of RU2298416C2 publication Critical patent/RU2298416C2/ru

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RU2004105031/15A 2001-07-20 2002-07-19 Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi RU2298416C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101127 2001-07-20
DKPA200101127 2001-07-20

Publications (2)

Publication Number Publication Date
RU2004105031A RU2004105031A (ru) 2005-04-20
RU2298416C2 true RU2298416C2 (ru) 2007-05-10

Family

ID=8160632

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2004105031/15A RU2298416C2 (ru) 2001-07-20 2002-07-19 Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi

Country Status (16)

Country Link
EP (1) EP1411973A1 (ko)
JP (1) JP2004534855A (ko)
KR (1) KR20040015821A (ko)
CN (1) CN1304050C (ko)
AU (1) AU2002354846B2 (ko)
BR (1) BR0211256A (ko)
CA (1) CA2452677A1 (ko)
CZ (1) CZ200439A3 (ko)
HU (1) HUP0400976A3 (ko)
IL (1) IL159622A0 (ko)
MX (1) MXPA04000415A (ko)
NO (1) NO20040235L (ko)
PL (1) PL369077A1 (ko)
RU (1) RU2298416C2 (ko)
WO (1) WO2003007983A1 (ko)
ZA (1) ZA200400012B (ko)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9433664B2 (en) 2010-10-06 2016-09-06 Medimmune Limited Factor II and fibrinogen for treatment of haemostatic disorders
RU2800719C2 (ru) * 2017-02-10 2023-07-26 Шанхай Бенемае Фармасьютикалз Корпорэйшн Антитела к фактору xi
US11958911B2 (en) 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100411684C (zh) 1999-07-14 2008-08-20 诺沃挪第克健康护理股份公司 FVIIa或组织因子拮抗剂在调节基因表达和细胞迁移或趋化中的应用
CN1863908B (zh) 2003-09-09 2010-08-04 诺和诺德医疗保健公司 凝固因子ⅶ多肽
KR20060118486A (ko) * 2003-11-20 2006-11-23 노보 노르디스크 헬스 케어 악티엔게젤샤프트 인자 ｘｉ의 치료적 사용
CA2555025A1 (en) * 2004-02-05 2005-08-18 Novo Nordisk Health Care Ag Use of factor viia factor for treating trauma
WO2006128497A1 (en) * 2005-06-01 2006-12-07 Novo Nordisk A/S Pharmaceutical formulation of factor xi
LT2379096T (lt) 2008-12-19 2019-12-27 Baxalta GmbH Tfpi inhibitoriai ir vartojimo būdai
KR101784030B1 (ko) 2010-03-19 2017-10-10 백스터 인터내셔널 인코포레이티드 Tfpi 저해제 및 사용 방법
CN104302306B (zh) 2012-03-21 2019-03-22 百深有限责任公司 Tfpi抑制剂及其使用方法
MX2016009975A (es) * 2014-01-31 2016-10-31 Dana Farber Cancer Inst Inc Derivados de dihidropteridinona y sus usos.
AU2016276963C1 (en) 2015-06-12 2021-08-05 Dana-Farber Cancer Institute, Inc. Combination therapy of transcription inhibitors and kinase inhibitors
EP3380100A4 (en) 2015-11-25 2019-10-02 Dana-Farber Cancer Institute, Inc. BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59116213A (ja) * 1982-12-24 1984-07-05 Unitika Ltd エアゾ−ル組成物
AU593042B2 (en) * 1985-11-26 1990-02-01 Novo Nordisk Health Care Ag Compositions and methods for the treatment of bleeding disorders
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa
FR2676231A1 (fr) * 1991-05-07 1992-11-13 Aetsrn Concentre de facteur xi de la coagulation sanguine a haute activite specifique, approprie a usage therapeutique et son procede de preparation.
WO2002022776A2 (en) * 2000-09-13 2002-03-21 Novo Nordisk A/S Human coagulation factor vii variants

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TORBET J.The trombin activation pathway modulates the assembly, structure and lysis of human plasma clots in vitro/. Thromb.Haemost., 1995, May, v.73(5), p.785-792. *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9433664B2 (en) 2010-10-06 2016-09-06 Medimmune Limited Factor II and fibrinogen for treatment of haemostatic disorders
RU2606155C2 (ru) * 2010-10-06 2017-01-10 Медиммьюн Лимитед Фактор ii и фибриноген для лечения гемостатических нарушений
RU2800719C2 (ru) * 2017-02-10 2023-07-26 Шанхай Бенемае Фармасьютикалз Корпорэйшн Антитела к фактору xi
US11958911B2 (en) 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody

Also Published As

Publication number Publication date
HUP0400976A2 (hu) 2004-08-30
HUP0400976A3 (en) 2006-01-30
BR0211256A (pt) 2004-07-27
WO2003007983A1 (en) 2003-01-30
MXPA04000415A (es) 2004-11-22
ZA200400012B (en) 2004-08-17
EP1411973A1 (en) 2004-04-28
KR20040015821A (ko) 2004-02-19
CA2452677A1 (en) 2003-01-30
PL369077A1 (en) 2005-04-18
CN1304050C (zh) 2007-03-14
CN1556710A (zh) 2004-12-22
CZ200439A3 (cs) 2005-03-16
JP2004534855A (ja) 2004-11-18
AU2002354846B2 (en) 2007-08-02
NO20040235L (no) 2004-03-17
IL159622A0 (en) 2004-06-01
RU2004105031A (ru) 2005-04-20

Similar Documents

Publication Publication Date Title
RU2311923C2 (ru) Комбинированное применение полипептидов фактора vii и полипептидов фактора viii
US7125846B2 (en) Pharmaceutical composition comprising factor VII polypeptides and factor V polypeptides
US20080102064A1 (en) Pharmaceutical Composition Comprising Factor VII Polypeptides and Protein C Inhibitors
US20080058266A1 (en) Pharmaceutical Compositions Comprising Factor VII Polypeptides and Factor XI Polypeptides
US20050266006A1 (en) Pharmaceutical composition comprising factor VII polypeptides and tissue plasminogen inhibitors
US7078479B2 (en) Pharmaceutical composition comprising factor VII polypeptides and alpha2-antiplasmin polypeptides
US20080069810A1 (en) Pharmaceutical Composition Comprising Factor VII Polypeptides and TAFI Polypeptides
JP2005526004A (ja) 第ｖｉｉ因子ポリペプチドおよびトラネキサム酸を含む薬学的組成物
RU2298416C2 (ru) Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi
US20070219135A1 (en) Pharmaceutical Composition Comprising Factor VII Polypeptides and PAI-1 Polypeptide
AU2002354846A1 (en) Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides
US20080075709A1 (en) Pharmaceutical Composition Comprising Factor VII Polypeptides And Thrombomodulin Polypeptides
US20040258690A1 (en) Pharmaceutical composition comprising factor VII polypeptides and protein S inhibitors
AU2002340779B2 (en) Pharmaceutical composition comprising factor VII polypeptides and factor V polypeptides
RU2304980C2 (ru) Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды pai-1
JP2005510513A (ja) Ｖｉｉ因子ポリペプチドおよびｔａｆｉポリペプチドを含む薬学的組成物
JP2005510516A (ja) Ｖｉｉ因子ポリペプチドおよびプロテインｓ阻害剤を含む薬学的組成物
JP2005511601A (ja) 第ｖｉｉ因子ポリペプチドおよび組織プラスミノゲン阻害剤を含む薬学的組成物
US20080057059A1 (en) Pharmaceutical Composition Comprising Factor VII Polypeptides and Protein S Inhibitors
JP2005515175A (ja) 第ｖｉｉ因子ポリペプチドおよびアルファ２−抗プラスミンポリペプチドを含む薬学的組成物
JP2005511600A (ja) Ｖｉｉ因子ポリペプチドおよびトロンボモジュリンポリペプチドを含む薬学的組成物

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20080720