CA2452677A1 - Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides - Google Patents

Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides Download PDF

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Publication number
CA2452677A1
CA2452677A1 CA002452677A CA2452677A CA2452677A1 CA 2452677 A1 CA2452677 A1 CA 2452677A1 CA 002452677 A CA002452677 A CA 002452677A CA 2452677 A CA2452677 A CA 2452677A CA 2452677 A1 CA2452677 A1 CA 2452677A1
Authority
CA
Canada
Prior art keywords
factor
factor vii
related polypeptide
vii
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002452677A
Other languages
English (en)
French (fr)
Inventor
Rasmus Rojkjaer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk Health Care AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2452677A1 publication Critical patent/CA2452677A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4846Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA002452677A 2001-07-20 2002-07-19 Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides Abandoned CA2452677A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200101127 2001-07-20
DKPA200101127 2001-07-20
PCT/DK2002/000505 WO2003007983A1 (en) 2001-07-20 2002-07-19 Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides

Publications (1)

Publication Number Publication Date
CA2452677A1 true CA2452677A1 (en) 2003-01-30

Family

ID=8160632

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002452677A Abandoned CA2452677A1 (en) 2001-07-20 2002-07-19 Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides

Country Status (16)

Country Link
EP (1) EP1411973A1 (ko)
JP (1) JP2004534855A (ko)
KR (1) KR20040015821A (ko)
CN (1) CN1304050C (ko)
AU (1) AU2002354846B2 (ko)
BR (1) BR0211256A (ko)
CA (1) CA2452677A1 (ko)
CZ (1) CZ200439A3 (ko)
HU (1) HUP0400976A3 (ko)
IL (1) IL159622A0 (ko)
MX (1) MXPA04000415A (ko)
NO (1) NO20040235L (ko)
PL (1) PL369077A1 (ko)
RU (1) RU2298416C2 (ko)
WO (1) WO2003007983A1 (ko)
ZA (1) ZA200400012B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100411684C (zh) 1999-07-14 2008-08-20 诺沃挪第克健康护理股份公司 FVIIa或组织因子拮抗剂在调节基因表达和细胞迁移或趋化中的应用
CN1863908B (zh) 2003-09-09 2010-08-04 诺和诺德医疗保健公司 凝固因子ⅶ多肽
KR20060118486A (ko) * 2003-11-20 2006-11-23 노보 노르디스크 헬스 케어 악티엔게젤샤프트 인자 xi의 치료적 사용
CA2555025A1 (en) * 2004-02-05 2005-08-18 Novo Nordisk Health Care Ag Use of factor viia factor for treating trauma
WO2006128497A1 (en) * 2005-06-01 2006-12-07 Novo Nordisk A/S Pharmaceutical formulation of factor xi
LT2379096T (lt) 2008-12-19 2019-12-27 Baxalta GmbH Tfpi inhibitoriai ir vartojimo būdai
KR101784030B1 (ko) 2010-03-19 2017-10-10 백스터 인터내셔널 인코포레이티드 Tfpi 저해제 및 사용 방법
MX343784B (es) 2010-10-06 2016-11-23 Medimmune Ltd Factor ii y fibrinogeno para tratamiento de trastornos hemostaticos.
CN104302306B (zh) 2012-03-21 2019-03-22 百深有限责任公司 Tfpi抑制剂及其使用方法
MX2016009975A (es) * 2014-01-31 2016-10-31 Dana Farber Cancer Inst Inc Derivados de dihidropteridinona y sus usos.
AU2016276963C1 (en) 2015-06-12 2021-08-05 Dana-Farber Cancer Institute, Inc. Combination therapy of transcription inhibitors and kinase inhibitors
EP3380100A4 (en) 2015-11-25 2019-10-02 Dana-Farber Cancer Institute, Inc. BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF
US11958911B2 (en) 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59116213A (ja) * 1982-12-24 1984-07-05 Unitika Ltd エアゾ−ル組成物
AU593042B2 (en) * 1985-11-26 1990-02-01 Novo Nordisk Health Care Ag Compositions and methods for the treatment of bleeding disorders
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa
FR2676231A1 (fr) * 1991-05-07 1992-11-13 Aetsrn Concentre de facteur xi de la coagulation sanguine a haute activite specifique, approprie a usage therapeutique et son procede de preparation.
WO2002022776A2 (en) * 2000-09-13 2002-03-21 Novo Nordisk A/S Human coagulation factor vii variants

Also Published As

Publication number Publication date
RU2298416C2 (ru) 2007-05-10
HUP0400976A2 (hu) 2004-08-30
HUP0400976A3 (en) 2006-01-30
BR0211256A (pt) 2004-07-27
WO2003007983A1 (en) 2003-01-30
MXPA04000415A (es) 2004-11-22
ZA200400012B (en) 2004-08-17
EP1411973A1 (en) 2004-04-28
KR20040015821A (ko) 2004-02-19
PL369077A1 (en) 2005-04-18
CN1304050C (zh) 2007-03-14
CN1556710A (zh) 2004-12-22
CZ200439A3 (cs) 2005-03-16
JP2004534855A (ja) 2004-11-18
AU2002354846B2 (en) 2007-08-02
NO20040235L (no) 2004-03-17
IL159622A0 (en) 2004-06-01
RU2004105031A (ru) 2005-04-20

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued