RU2220980C2 - Химерное антитело, которое связывается с cd40 человека (варианты), молекула нуклеиновой кислоты (варианты), вектор экспрессии (варианты), гуманизированное антитело (варианты), фармацевтическая композиция для лечения заболевания, опосредованного т-клетками (варианты), способ лечения больного от заболевания, опосредованного т-клетками (варианты) - Google Patents

Химерное антитело, которое связывается с cd40 человека (варианты), молекула нуклеиновой кислоты (варианты), вектор экспрессии (варианты), гуманизированное антитело (варианты), фармацевтическая композиция для лечения заболевания, опосредованного т-клетками (варианты), способ лечения больного от заболевания, опосредованного т-клетками (варианты) Download PDF

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RU2220980C2
RU2220980C2 RU2000124084/13A RU2000124084A RU2220980C2 RU 2220980 C2 RU2220980 C2 RU 2220980C2 RU 2000124084/13 A RU2000124084/13 A RU 2000124084/13A RU 2000124084 A RU2000124084 A RU 2000124084A RU 2220980 C2 RU2220980 C2 RU 2220980C2
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seq
variable region
sequence
variants
human
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RU2000124084/13A
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English (en)
Russian (ru)
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RU2000124084A (ru
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Алехандро А. АРАФФО (US)
Алехандро А. АРАФФО
Диан ХОЛЛЕНБОГ (US)
Диан ХОЛЛЕНБОГ
Энтони В. СИАДЭК (US)
Энтони В. СИАДЭК
Карен К. БЕРРИ (US)
Карен К. БЕРРИ
Линда Дж. ХАРРИС (US)
Линда Дж. ХАРРИС
Барбара А. ТОРН (US)
Барбара А. ТОРН
Юрген БАЖОРАТ (US)
Юрген БАЖОРАТ
Уиль м Д. ХЬЮЗ (US)
Уильям Д. ХЬЮЗ
Херрен ВУ (US)
Херрен ВУ
Джефри Д. УОТКИНС (US)
Джефри Д. УОТКИНС
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Бристол-Маерс Сквибб Компани
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2000124084/13A 1998-02-19 1999-02-10 Химерное антитело, которое связывается с cd40 человека (варианты), молекула нуклеиновой кислоты (варианты), вектор экспрессии (варианты), гуманизированное антитело (варианты), фармацевтическая композиция для лечения заболевания, опосредованного т-клетками (варианты), способ лечения больного от заболевания, опосредованного т-клетками (варианты) RU2220980C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/026,291 1998-02-19
US09/026,291 US6051228A (en) 1998-02-19 1998-02-19 Antibodies against human CD40

Publications (2)

Publication Number Publication Date
RU2000124084A RU2000124084A (ru) 2003-11-10
RU2220980C2 true RU2220980C2 (ru) 2004-01-10

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RU2000124084/13A RU2220980C2 (ru) 1998-02-19 1999-02-10 Химерное антитело, которое связывается с cd40 человека (варианты), молекула нуклеиновой кислоты (варианты), вектор экспрессии (варианты), гуманизированное антитело (варианты), фармацевтическая композиция для лечения заболевания, опосредованного т-клетками (варианты), способ лечения больного от заболевания, опосредованного т-клетками (варианты)

Country Status (31)

Country Link
US (3) US6051228A (https=)
EP (1) EP1054692A4 (https=)
JP (1) JP2002503495A (https=)
KR (1) KR100564376B1 (https=)
CN (1) CN1198647C (https=)
AR (1) AR018101A1 (https=)
AU (1) AU751064B2 (https=)
BG (1) BG65010B1 (https=)
BR (1) BR9908045A (https=)
CA (1) CA2321165A1 (https=)
CO (1) CO4830493A1 (https=)
CZ (1) CZ20003008A3 (https=)
EE (1) EE200000470A (https=)
GE (1) GEP20033016B (https=)
HU (1) HUP0100763A3 (https=)
ID (1) ID25792A (https=)
IL (2) IL137294A0 (https=)
LT (1) LT4837B (https=)
LV (1) LV12561B (https=)
MY (1) MY121464A (https=)
NO (1) NO20004133L (https=)
NZ (1) NZ505696A (https=)
PE (1) PE20000268A1 (https=)
PL (1) PL197143B1 (https=)
RU (1) RU2220980C2 (https=)
SK (1) SK12092000A3 (https=)
TR (1) TR200002405T2 (https=)
TW (1) TWI226334B (https=)
UA (1) UA71909C2 (https=)
WO (1) WO1999042075A2 (https=)
ZA (1) ZA991307B (https=)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
RU2491295C2 (ru) * 2006-05-09 2013-08-27 Пандженетикс Б.В. Моноклональное антитело-антагонист против cd40 человека

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