RU2215740C2 - Оксазолидиноновые производные и фармацевтические композиции на их основе - Google Patents

Оксазолидиноновые производные и фармацевтические композиции на их основе Download PDF

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Publication number
RU2215740C2
RU2215740C2 RU2000114891/04A RU2000114891A RU2215740C2 RU 2215740 C2 RU2215740 C2 RU 2215740C2 RU 2000114891/04 A RU2000114891/04 A RU 2000114891/04A RU 2000114891 A RU2000114891 A RU 2000114891A RU 2215740 C2 RU2215740 C2 RU 2215740C2
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Russia
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oxo
formula
compound
mixture
methyl
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RU2000114891/04A
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English (en)
Russian (ru)
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RU2000114891A (ru
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Джексон Б. Мл. ХЕСТЕР
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Фармация Энд Апджон Компани
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
RU2000114891/04A 1997-11-12 1998-10-30 Оксазолидиноновые производные и фармацевтические композиции на их основе RU2215740C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6537697P 1997-11-12 1997-11-12
US60/065,376 1997-11-12

Publications (2)

Publication Number Publication Date
RU2000114891A RU2000114891A (ru) 2002-05-10
RU2215740C2 true RU2215740C2 (ru) 2003-11-10

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ID=22062294

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Application Number Title Priority Date Filing Date
RU2000114891/04A RU2215740C2 (ru) 1997-11-12 1998-10-30 Оксазолидиноновые производные и фармацевтические композиции на их основе

Country Status (21)

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US (1) US5998406A (https=)
EP (1) EP1030852B1 (https=)
JP (1) JP2001522849A (https=)
KR (1) KR20010031953A (https=)
CN (1) CN1154644C (https=)
AT (1) ATE250054T1 (https=)
AU (1) AU739055B2 (https=)
BR (1) BR9813985A (https=)
CA (1) CA2303959A1 (https=)
DE (1) DE69818294T2 (https=)
DK (1) DK1030852T3 (https=)
ES (1) ES2207010T3 (https=)
HU (1) HUP0100470A3 (https=)
IL (1) IL136062A (https=)
NO (1) NO317291B1 (https=)
NZ (1) NZ504503A (https=)
PT (1) PT1030852E (https=)
RU (1) RU2215740C2 (https=)
SK (1) SK284577B6 (https=)
TR (1) TR200001330T2 (https=)
WO (1) WO1999024428A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2559620C2 (ru) * 2003-12-18 2015-08-10 Донг-А Ст Ко., Лтд. Новые производные оксазолидинона, способ их получения и применение

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TR200003595T2 (tr) 1998-06-05 2001-07-23 Astrazeneca Ab Kimyasal bileşikler
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
DE19962924A1 (de) 1999-12-24 2001-07-05 Bayer Ag Substituierte Oxazolidinone und ihre Verwendung
KR100355345B1 (ko) * 2000-01-21 2002-10-12 한국과학기술연구원 티오펜환을 함유한 신규한 옥사졸리디논 유도체, 그의 제조방법 및 조성물
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
DE10129725A1 (de) 2001-06-20 2003-01-02 Bayer Ag Kombinationstherapie substituierter Oxazolidinone
ES2258234T3 (es) 2002-08-12 2006-08-16 PHARMACIA & UPJOHN COMPANY LLC N-aril-2-oxazolidinonas y sus derivados.
DE10300111A1 (de) 2003-01-07 2004-07-15 Bayer Healthcare Ag Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid
BRPI0413838A (pt) * 2003-08-25 2006-10-24 Warner Lambert Co compostos de ariloxazolidinona antimicrobianos
DE10355461A1 (de) 2003-11-27 2005-06-23 Bayer Healthcare Ag Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung
EP1819699A2 (en) * 2004-11-29 2007-08-22 Pharmacia & Upjohn Company LLC Diazepine oxazolidinones as antibacterial agents
DE102004062475A1 (de) * 2004-12-24 2006-07-06 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung
EP1685841A1 (en) * 2005-01-31 2006-08-02 Bayer Health Care Aktiengesellschaft Prevention and treatment of thromboembolic disorders
WO2007000644A1 (en) 2005-06-29 2007-01-04 Pharmacia & Upjohn Company Llc Homomorpholine oxazolidinones as antibacterial agents
DE102005045518A1 (de) * 2005-09-23 2007-03-29 Bayer Healthcare Ag 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung
DE102005047561A1 (de) 2005-10-04 2007-04-05 Bayer Healthcare Ag Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
US8188270B2 (en) 2005-10-04 2012-05-29 Bayer Schering Pharma Aktiengesellschaft Polymorphous form of 5-chloro-N-({(5S)-2-oxo-3[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidine-5-yl}-methyl)-2-thiophene carboxamide
DE102005047558A1 (de) * 2005-10-04 2008-02-07 Bayer Healthcare Ag Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen
KR20080110877A (ko) 2006-03-31 2008-12-19 재단법인 이쯔우 연구소 헤테로환을 갖는 신규 화합물
WO2009044777A1 (ja) * 2007-10-02 2009-04-09 Research Foundation Itsuu Laboratory ７員ヘテロ環を有するオキサゾリジノン誘導体
WO2012059823A1 (en) 2010-11-03 2012-05-10 Wockhardt Limited Process for the preparation of phosphoric acid mono- (l-{4- [(s) -5- (acetylaminomethyl) - 2 - oxo - oxazolidin- 3 - yl] - 2, 6 - difluorophenyl} - 4 -methoxymethylpiperidin- 4 - yl) ester
WO2015173664A1 (en) 2014-05-14 2015-11-19 Wockhardt Limited Process for the preparation of (5s)-n-{3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023384A1 (en) * 1992-05-08 1993-11-25 The Upjohn Company Oxazolidinones containing a substituted diazine moiety and their use as antimicrobials
WO1995014684A1 (en) * 1993-11-22 1995-06-01 The Upjohn Company Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones
WO1995025106A1 (en) * 1994-03-15 1995-09-21 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions containing them
WO1997027188A1 (en) * 1996-01-27 1997-07-31 Zeneca Limited Piperazinonephenyloxazolidinone derivatives and their use as antibacterial agents

Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
US4801600A (en) * 1987-10-09 1989-01-31 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
CA1320730C (en) * 1987-10-16 1993-07-27 The Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
EP0316594B1 (en) * 1987-10-21 1993-09-29 The Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl ethenylbenzene derivatives useful as antibacterial agents
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
AU617871B2 (en) * 1988-09-15 1991-12-05 Pharmacia & Upjohn Company In position 3 substituted-5-beta-amidomethyl-oxazolidin-2- ones
ATE146783T1 (de) * 1991-11-01 1997-01-15 Upjohn Co Substituierte aryl- und heteroaryl- phenyloxazolidinone

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993023384A1 (en) * 1992-05-08 1993-11-25 The Upjohn Company Oxazolidinones containing a substituted diazine moiety and their use as antimicrobials
WO1995014684A1 (en) * 1993-11-22 1995-06-01 The Upjohn Company Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones
WO1995025106A1 (en) * 1994-03-15 1995-09-21 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions containing them
WO1997027188A1 (en) * 1996-01-27 1997-07-31 Zeneca Limited Piperazinonephenyloxazolidinone derivatives and their use as antibacterial agents

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2559620C2 (ru) * 2003-12-18 2015-08-10 Донг-А Ст Ко., Лтд. Новые производные оксазолидинона, способ их получения и применение
US9163043B2 (en) 2003-12-18 2015-10-20 Dong-A St Co., Ltd. Oxazolidinone derivatives

Also Published As

Publication number Publication date
CN1154644C (zh) 2004-06-23
US5998406A (en) 1999-12-07
BR9813985A (pt) 2000-09-26
CA2303959A1 (en) 1999-05-20
CN1271358A (zh) 2000-10-25
ES2207010T3 (es) 2004-05-16
DK1030852T3 (da) 2003-12-22
NO20002434L (no) 2000-05-11
NO20002434D0 (no) 2000-05-11
DE69818294T2 (de) 2004-07-08
SK6182000A3 (en) 2000-12-11
EP1030852A1 (en) 2000-08-30
IL136062A0 (en) 2001-05-20
HK1030373A1 (en) 2001-05-04
HUP0100470A3 (en) 2002-08-28
WO1999024428A1 (en) 1999-05-20
NZ504503A (en) 2002-10-25
AU739055B2 (en) 2001-10-04
TR200001330T2 (tr) 2000-11-21
PT1030852E (pt) 2004-02-27
EP1030852B1 (en) 2003-09-17
SK284577B6 (sk) 2005-07-01
JP2001522849A (ja) 2001-11-20
NO317291B1 (no) 2004-10-04
HUP0100470A2 (hu) 2002-05-29
KR20010031953A (ko) 2001-04-16
IL136062A (en) 2004-02-08
ATE250054T1 (de) 2003-10-15
AU1277899A (en) 1999-05-31
DE69818294D1 (de) 2003-10-23

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20061031