RU2214824C2 - Комбинация ингибитора обратного захвата 5-ht и антагониста или частичного агониста h5-ht1b - Google Patents

Комбинация ингибитора обратного захвата 5-ht и антагониста или частичного агониста h5-ht1b Download PDF

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Publication number
RU2214824C2
RU2214824C2 RU2000109563/14A RU2000109563A RU2214824C2 RU 2214824 C2 RU2214824 C2 RU 2214824C2 RU 2000109563/14 A RU2000109563/14 A RU 2000109563/14A RU 2000109563 A RU2000109563 A RU 2000109563A RU 2214824 C2 RU2214824 C2 RU 2214824C2
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Prior art keywords
methylpiperazin
combination
tetrahydro
naphthyl
morpholinobenzamide
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RU2000109563/14A
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English (en)
Russian (ru)
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RU2000109563A (ru
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Стефан БЕРГ (SE)
Стефан Берг
Сванте РОСС (SE)
Сванте Росс
Сет-Олов ТОРБЕРГ (SE)
Сет-Олов Торберг
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Астразенека Аб
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Winding, Rewinding, Material Storage Devices (AREA)
  • Replacement Of Web Rolls (AREA)
RU2000109563/14A 1997-09-18 1998-09-09 Комбинация ингибитора обратного захвата 5-ht и антагониста или частичного агониста h5-ht1b RU2214824C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9703375A SE9703375D0 (sv) 1997-09-18 1997-09-18 A new combination
SE9703375-7 1997-09-18

Publications (2)

Publication Number Publication Date
RU2000109563A RU2000109563A (ru) 2002-01-27
RU2214824C2 true RU2214824C2 (ru) 2003-10-27

Family

ID=20408295

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2000109563/14A RU2214824C2 (ru) 1997-09-18 1998-09-09 Комбинация ингибитора обратного захвата 5-ht и антагониста или частичного агониста h5-ht1b

Country Status (29)

Country Link
US (1) US6159971A (https=)
EP (1) EP1014985B1 (https=)
JP (1) JP2001516718A (https=)
KR (1) KR20010024076A (https=)
CN (1) CN1195519C (https=)
AR (1) AR015448A1 (https=)
AT (1) ATE240733T1 (https=)
AU (1) AU752722B2 (https=)
BR (1) BR9812088A (https=)
CA (1) CA2302382A1 (https=)
DE (1) DE69814882T2 (https=)
DK (1) DK1014985T3 (https=)
EE (1) EE04141B1 (https=)
ES (1) ES2200370T3 (https=)
HU (1) HUP0200602A3 (https=)
IL (1) IL134776A0 (https=)
IS (1) IS5406A (https=)
MY (1) MY116280A (https=)
NO (1) NO20001399L (https=)
NZ (1) NZ503171A (https=)
PL (1) PL339371A1 (https=)
PT (1) PT1014985E (https=)
RU (1) RU2214824C2 (https=)
SE (1) SE9703375D0 (https=)
SK (1) SK2852000A3 (https=)
TR (1) TR200000727T2 (https=)
TW (1) TW589183B (https=)
WO (1) WO1999013877A1 (https=)
ZA (1) ZA987817B (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9601110D0 (sv) 1996-03-22 1996-03-22 Astra Ab Substituted 1,2,3,4-tetrahydronaphthalene derivatives
AR021155A1 (es) * 1999-07-08 2002-06-12 Lundbeck & Co As H Tratamiento de desordenes neuroticos
UA77650C2 (en) * 1999-12-06 2007-01-15 Lundbeck & Co As H Use of serotonin reuptake inhibitor in combination with deramcyclane
WO2002066454A1 (fr) * 2001-02-21 2002-08-29 Sankyo Company, Limited Derives de chromene
EA200301195A1 (ru) * 2001-05-01 2004-04-29 Х. Лундбекк А/С Применение энантиомерно чистого эсциталопрама
ATE424825T1 (de) * 2001-07-20 2009-03-15 Psychogenics Inc Behandlung von hyperaktivitätsstörungen und aufmerksamkeitsdefiziten
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
UA78974C2 (en) 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
SE0203778D0 (sv) * 2002-12-09 2002-12-09 Astrazeneca Ab A new oral immediated release dosage form
AR047553A1 (es) 2003-07-04 2006-01-25 Lundbeck & Co As H La combinacion de un inhibidor de reabsorcion de serotonina y agomelatina
KR100511288B1 (ko) * 2003-11-14 2005-08-31 엘지전자 주식회사 4대의 압축기를 구비한 공기조화기의 실외기
US20060217394A1 (en) * 2005-02-23 2006-09-28 Silvan S. Tomkins Institute, Inc. Treatment of anhedonia
ES2646326T3 (es) 2005-08-03 2017-12-13 Sprout Pharmaceuticals, Inc. Uso de flibanserina en el tratamiento de la obesidad
FR2890862B1 (fr) * 2005-09-19 2008-01-25 Sanofi Aventis Sa Association d'agoniste aux recepteurs beta 3 et d'inhibiteur de la recapture de monoamnies, compostion pharmaceutique la contenant et son utilisation en therapeutique.
CA2626134C (en) 2005-10-29 2013-12-24 Boehringer Ingelheim International Gmbh Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders
US8748419B2 (en) 2006-06-16 2014-06-10 Theracos, Inc. Treating obesity with muscarinic receptor M1 antagonists
RU2455981C2 (ru) * 2006-06-16 2012-07-20 Теракос, Инк. Лечение ожирения антагонистами мускаринового рецептора м1
US7893053B2 (en) 2006-06-16 2011-02-22 Theracos, Inc. Treating psychological conditions using muscarinic receptor M1 antagonists
JP2009541443A (ja) 2006-06-30 2009-11-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 尿失禁及び関連疾患の治療のためのフリバンセリン
EP2054041A2 (en) 2006-08-14 2009-05-06 Boehringer Ingelheim International GmbH Formulations of flibanserin and method for manufacturing the same
CL2007002214A1 (es) 2006-08-14 2008-03-07 Boehringer Ingelheim Int Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp
IL197129A (en) 2006-08-25 2014-08-31 Boehringer Ingelheim Int Controlled release system and method for production
CL2008002693A1 (es) 2007-09-12 2009-10-16 Boehringer Ingelheim Int Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0533268A1 (en) * 1991-09-18 1993-03-24 Glaxo Group Limited Benzanilide derivatives as 5-HT1D antagonists
EP0533267A1 (en) * 1991-09-18 1993-03-24 Glaxo Group Limited Benzanilide derivatives as 5-HT1D antagonists
RU2000109560A (ru) * 1997-09-18 2002-02-10 Астразенека Аб Комбинация ингибитора моноаминоксидазы и селективного антагониста или частичного агониста н5-нт1b

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9601110D0 (sv) * 1996-03-22 1996-03-22 Astra Ab Substituted 1,2,3,4-tetrahydronaphthalene derivatives
SE9703374D0 (sv) * 1997-09-18 1997-09-18 Astra Ab A new combination

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0533268A1 (en) * 1991-09-18 1993-03-24 Glaxo Group Limited Benzanilide derivatives as 5-HT1D antagonists
EP0533267A1 (en) * 1991-09-18 1993-03-24 Glaxo Group Limited Benzanilide derivatives as 5-HT1D antagonists
RU2000109560A (ru) * 1997-09-18 2002-02-10 Астразенека Аб Комбинация ингибитора моноаминоксидазы и селективного антагониста или частичного агониста н5-нт1b
RU2000109558A (ru) * 1997-09-18 2002-02-10 Астразенека Аб Комбинация селективного антагониста 5-нт1a и селективного антагониста или частичного агониста н5-нт1b

Also Published As

Publication number Publication date
DK1014985T3 (da) 2003-09-15
AR015448A1 (es) 2001-05-02
TR200000727T2 (tr) 2000-09-21
EE04141B1 (et) 2003-10-15
PT1014985E (pt) 2003-10-31
CN1195519C (zh) 2005-04-06
CA2302382A1 (en) 1999-03-25
JP2001516718A (ja) 2001-10-02
US6159971A (en) 2000-12-12
HUP0200602A3 (en) 2003-04-28
AU9193098A (en) 1999-04-05
ES2200370T3 (es) 2004-03-01
DE69814882T2 (de) 2004-05-19
NZ503171A (en) 2002-02-01
ATE240733T1 (de) 2003-06-15
NO20001399L (no) 2000-05-10
IS5406A (is) 2000-03-15
MY116280A (en) 2003-12-31
ZA987817B (en) 1999-03-18
EP1014985B1 (en) 2003-05-21
SE9703375D0 (sv) 1997-09-18
DE69814882D1 (de) 2003-06-26
NO20001399D0 (no) 2000-03-17
EE200000141A (et) 2001-02-15
PL339371A1 (en) 2000-12-18
HUP0200602A2 (hu) 2002-07-29
SK2852000A3 (en) 2000-09-12
BR9812088A (pt) 2000-09-26
AU752722B2 (en) 2002-09-26
WO1999013877A1 (en) 1999-03-25
KR20010024076A (ko) 2001-03-26
CN1278729A (zh) 2001-01-03
TW589183B (en) 2004-06-01
EP1014985A1 (en) 2000-07-05
IL134776A0 (en) 2001-04-30
HK1032739A1 (en) 2001-08-03

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Effective date: 20050910