RU2167864C2 - Производные индолин-2-она, способ их получения и содержащие их фармацевтические композиции - Google Patents

Производные индолин-2-она, способ их получения и содержащие их фармацевтические композиции Download PDF

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RU2167864C2
RU2167864C2 RU98109945/04A RU98109945A RU2167864C2 RU 2167864 C2 RU2167864 C2 RU 2167864C2 RU 98109945/04 A RU98109945/04 A RU 98109945/04A RU 98109945 A RU98109945 A RU 98109945A RU 2167864 C2 RU2167864 C2 RU 2167864C2
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indolin
formula
spiro
cyclohexane
tert
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RU98109945A (ru
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ФУЛОН Лоик (FR)
Фулон Лоик
ГАРСИА Жорж (FR)
Гарсиа Жорж
СЕРРАДЕЙ-ЛЕ ГАЛЬ Клодин (FR)
Серрадей-Ле Галь Клодин
ВАЛЕТТ Жерар (FR)
Валетт Жерар
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Санофи
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    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU98109945/04A 1995-10-24 1996-10-24 Производные индолин-2-она, способ их получения и содержащие их фармацевтические композиции RU2167864C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR95/12533 1995-10-24
FR9512533A FR2740136B1 (fr) 1995-10-24 1995-10-24 Derives d'indolin-2-one, procede pour leur preparation et les compositions pharmaceutiques les contenant

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RU98109945A RU98109945A (ru) 2000-04-27
RU2167864C2 true RU2167864C2 (ru) 2001-05-27

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US (2) US5994350A (enExample)
EP (1) EP0873309B1 (enExample)
JP (2) JP3274471B2 (enExample)
KR (1) KR100298925B1 (enExample)
CN (1) CN1106384C (enExample)
AR (1) AR004225A1 (enExample)
AT (1) ATE229940T1 (enExample)
AU (1) AU715841B2 (enExample)
BR (1) BR9611198A (enExample)
CZ (1) CZ295585B6 (enExample)
DE (1) DE69625517T2 (enExample)
DK (1) DK0873309T3 (enExample)
EE (1) EE04433B1 (enExample)
ES (1) ES2191769T3 (enExample)
FR (1) FR2740136B1 (enExample)
HU (1) HUP9900331A3 (enExample)
IL (1) IL124002A (enExample)
IN (1) IN185328B (enExample)
IS (1) IS1949B (enExample)
MY (1) MY115864A (enExample)
NO (1) NO310974B1 (enExample)
NZ (1) NZ320352A (enExample)
PL (1) PL187093B1 (enExample)
RU (1) RU2167864C2 (enExample)
SK (1) SK284546B6 (enExample)
TR (1) TR199800719T2 (enExample)
TW (1) TW474917B (enExample)
UA (1) UA59345C2 (enExample)
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RU2420529C2 (ru) * 2006-01-05 2011-06-10 Ф. Хоффманн-Ля Рош Аг Производные индол-3-ил-карбонил-спиро-пиперидина

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FR2775598A1 (fr) 1998-03-06 1999-09-10 Sanofi Sa Compositions pharmaceutiques contenant en association un antagoniste selectif des recepteurs v1a de l'arginine-vasopressine et un antagoniste selectif des recepteur v2 de l'arginine-vasopressine
FR2778103A1 (fr) * 1998-04-29 1999-11-05 Sanofi Sa Compositions pharmaceutiques contenant en association un antagoniste v1a de l'arginine-vasopressine et un antagoniste des recepteurs at1 de l'angiotensine ii
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HU225150B1 (en) * 1999-07-15 2006-07-28 Sanofi Aventis Novel process for producing 2-methoxy-4-(t-butylaminocarbonyl)-benzenesulfonyl chloride
HU225703B1 (en) * 1999-07-15 2007-06-28 Sanofi Aventis Process for producing spiro[cis-4-(betha-hydroxy-ethyloxi)-cyclohexane-[3h]indole]-2'[1'h]-one derivatives
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AR063278A1 (es) * 2006-10-12 2009-01-14 Xenon Pharmaceuticals Inc Compuestos de espiro-oxindol, una composicion farmaceutica que los comprende y su uso para el tratamiento de enfermedades o condiciones mediadas por los canales de sodio.
FR2927625B1 (fr) 2008-02-19 2010-03-12 Sanofi Aventis Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique
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JP5570172B2 (ja) * 2008-10-08 2014-08-13 持田製薬株式会社 喫煙による循環機能不全の予防/改善または治療剤
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MY165117A (en) 2010-02-26 2018-02-28 Xenon Pharmaceuticals Inc Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents
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MD4202C1 (ro) * 2012-03-21 2013-09-30 Институт Химии Академии Наук Молдовы Procedeu de obţinere a derivaţilor carbometoxi ai spiro[ciclopropan-oxindolilor]
CN108191864A (zh) * 2013-03-08 2018-06-22 沃克哈特有限公司 制备氧代磺酰氧基[(哌啶羰基)-肼基羰基]二氮杂-双环辛烷的方法
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TW201938171A (zh) 2017-12-15 2019-10-01 匈牙利商羅特格登公司 作為血管升壓素V1a受體拮抗劑之三環化合物
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EP0344634A1 (de) * 1988-06-03 1989-12-06 Roche Diagnostics GmbH Bicyclische Carboxamide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0636609A1 (fr) * 1993-07-30 1995-02-01 Sanofi Dérivés du 1-benzyl-1,3-dihydro-indol-2-one, leur préparation, les compositions pharmaceutiques en contenant
EP0636608A1 (fr) * 1993-07-30 1995-02-01 Sanofi Dérivés du 1-benzènesulfonyl-1,3-dihydro-indol-2-one, leur préparation, les compositions pharmaceutiques en contenant

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US5994350A (en) 1999-11-30
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