RU2074185C1 - Производное 4-дезокси-4-эпиподофиллотоксина или его фармацевтически приемлемая соль и фармацевтическая композиция на его основе - Google Patents

Производное 4-дезокси-4-эпиподофиллотоксина или его фармацевтически приемлемая соль и фармацевтическая композиция на его основе Download PDF

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RU2074185C1
RU2074185C1 SU925053149A SU5053149A RU2074185C1 RU 2074185 C1 RU2074185 C1 RU 2074185C1 SU 925053149 A SU925053149 A SU 925053149A SU 5053149 A SU5053149 A SU 5053149A RU 2074185 C1 RU2074185 C1 RU 2074185C1
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Russia
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group
formula
lower alkyl
deoxy
epipodophyllotoxin
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SU925053149A
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English (en)
Russian (ru)
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Терада Тадафуми
Фудзимото Катсухико
Номура Макото
Ямасита Дзунити
Такеда Сетсуо
Кобунаи Такаси
Ямагути Хидео
Виежба Константи
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Тайхо Фармасьютикал Компани Лимитед
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Epoxy Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Tea And Coffee (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Fireproofing Substances (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
SU925053149A 1991-01-25 1992-01-22 Производное 4-дезокси-4-эпиподофиллотоксина или его фармацевтически приемлемая соль и фармацевтическая композиция на его основе RU2074185C1 (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP8714091 1991-01-25
JP87140/91 1991-01-25
JP61706/91 1991-03-26
JP6170691 1991-03-26
JP90794/91 1991-04-22
JP9079491 1991-04-22
PCT/JP1992/000051 WO1992012982A1 (fr) 1991-01-25 1992-01-22 Derive de 4-desoxy-4-epipodophyllotoxine ou sel pharmaceutiquement acceptable de ce derive

Publications (1)

Publication Number Publication Date
RU2074185C1 true RU2074185C1 (ru) 1997-02-27

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ID=27297605

Family Applications (1)

Application Number Title Priority Date Filing Date
SU925053149A RU2074185C1 (ru) 1991-01-25 1992-01-22 Производное 4-дезокси-4-эпиподофиллотоксина или его фармацевтически приемлемая соль и фармацевтическая композиция на его основе

Country Status (17)

Country Link
US (3) US5489698A (fi)
EP (1) EP0522173B1 (fi)
JP (1) JP2631912B2 (fi)
KR (1) KR0145338B1 (fi)
CN (2) CN1035821C (fi)
AT (1) ATE159258T1 (fi)
AU (1) AU636076B2 (fi)
CA (1) CA2078662C (fi)
DE (1) DE69222698T2 (fi)
DK (1) DK0522173T3 (fi)
ES (1) ES2109993T3 (fi)
FI (1) FI101227B (fi)
HU (1) HU211961A9 (fi)
NO (1) NO301277B1 (fi)
RU (1) RU2074185C1 (fi)
TW (1) TW221441B (fi)
WO (1) WO1992012982A1 (fi)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2529676C2 (ru) * 2008-08-19 2014-09-27 Пьер Фабр Медикамент Новые (поли)аминоалкиламиноалкиламидные, алкил-мочевинные или алкил-сульфонамидные производные эпиподофиллотоксина, способ их получения и их применение в терапии в качестве противораковых средств

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2290524B (en) * 1993-03-13 1997-03-12 Philip Anton Strong A transfer system
US5713710A (en) * 1993-03-13 1998-02-03 Strong; Philip Anton Transfer system
EP2289549A3 (en) 1999-10-01 2011-06-15 Immunogen, Inc. Immunoconjugates for treating cancer
CN1101819C (zh) * 1999-10-21 2003-02-19 国家医药管理局上海医药工业研究院 具有抗肿瘤活性的4－β－碳取代－4－脱氧－4'－去甲表鬼臼毒素衍生物及合成方法和中间体
US20040076968A1 (en) 2000-07-14 2004-04-22 Gonzalo Acuna Method for detecting pre-disposition to hepatotoxicity
US6624317B1 (en) 2000-09-25 2003-09-23 The University Of North Carolina At Chapel Hill Taxoid conjugates as antimitotic and antitumor agents
US7176236B2 (en) 2002-06-21 2007-02-13 University Of North Carolina At Chapel Hill Water-soluble etoposide analogs and methods of use thereof
US6566393B1 (en) * 2002-06-21 2003-05-20 The University Of North Carolina At Chapel Hill Etoposide analogs and methods of use thereof
TWI307341B (en) * 2002-10-11 2009-03-11 Plantaceutica Inc Anticancer compounds
FR2859208B1 (fr) * 2003-09-02 2006-01-21 Servier Lab Nouveaux derives de 9-amino-podophyllotoxine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN100334090C (zh) * 2005-02-02 2007-08-29 南京医科大学 吡啶类鬼臼毒素化合物及其制备方法和在制备杀虫剂中的应用
GB0514685D0 (en) * 2005-07-19 2005-08-24 Pharma Mar Sa A ntineoplastic compounds
CA2803646A1 (en) 2010-07-02 2012-01-05 Angiochem Inc. Short and d-amino acid-containing polypeptides for therapeutic conjugates and uses thereof
US8987475B2 (en) 2010-08-31 2015-03-24 Alexar AB Process for preparing cyclolignans
CN103613600B (zh) * 2013-11-15 2017-01-04 湖北工业大学 具抗肿瘤活性的苯胺基鬼臼类衍生物及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61103883A (ja) * 1984-10-24 1986-05-22 Nippon Kayaku Co Ltd ４′−ハロゲノアセチル−４′−デメチルエピポドフイロトキシンの新規製造法
JPS6310789A (ja) * 1986-07-01 1988-01-18 Nippon Kayaku Co Ltd 新規ポドフイロトキシン誘導体
JPH01117885A (ja) * 1987-10-30 1989-05-10 Dai Ichi Seiyaku Co Ltd 新規ボドフィロトキシン誘導体及びその製造法
JPH01267855A (ja) * 1988-04-19 1989-10-25 Canon Inc 光学情報記録媒体
EP0366122A3 (en) * 1988-10-26 1991-03-20 Warner-Lambert Company Demethylepipodophyllotoxin derivatives
AU632796B2 (en) * 1989-02-23 1993-01-14 University Of North Carolina At Chapel Hill, The Etoposide analogues
JP2587705B2 (ja) * 1989-10-12 1997-03-05 大鵬薬品工業株式会社 ４―デソキシ―４―エピポドフィロトキシン誘導体
JP2001127792A (ja) * 1999-10-22 2001-05-11 Wittei:Kk 逐次処理によるネットワーク通信

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
1. Патент ЕР N 226208, кл. C 07 D 493/04, 1987. 2. Патент ЕР N 366122, кл. C 07 D 493/04, 1990. 3. Патент США N 5061791, кл. C 07 E 11/04, 1991. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2529676C2 (ru) * 2008-08-19 2014-09-27 Пьер Фабр Медикамент Новые (поли)аминоалкиламиноалкиламидные, алкил-мочевинные или алкил-сульфонамидные производные эпиподофиллотоксина, способ их получения и их применение в терапии в качестве противораковых средств

Also Published As

Publication number Publication date
CA2078662A1 (en) 1992-07-26
US5571914A (en) 1996-11-05
FI101227B1 (fi) 1998-05-15
EP0522173A4 (en) 1993-06-16
ATE159258T1 (de) 1997-11-15
WO1992012982A1 (fr) 1992-08-06
AU636076B2 (en) 1993-04-08
HU211961A9 (en) 1996-01-29
FI924285A0 (fi) 1992-09-24
ES2109993T3 (es) 1998-02-01
EP0522173A1 (en) 1993-01-13
TW221441B (fi) 1994-03-01
NO923721L (no) 1992-11-23
CN1046521C (zh) 1999-11-17
US5489698A (en) 1996-02-06
CN1064278A (zh) 1992-09-09
FI924285A (fi) 1992-09-24
US5536847A (en) 1996-07-16
FI101227B (fi) 1998-05-15
JP2631912B2 (ja) 1997-07-16
CA2078662C (en) 2000-04-04
AU1180592A (en) 1992-08-27
DE69222698D1 (de) 1997-11-20
KR0145338B1 (ko) 1998-07-15
NO923721D0 (no) 1992-09-24
NO301277B1 (no) 1997-10-06
DE69222698T2 (de) 1998-05-20
CN1126723A (zh) 1996-07-17
EP0522173B1 (en) 1997-10-15
DK0522173T3 (da) 1998-03-09
CN1035821C (zh) 1997-09-10

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