RU2018141084A3 - - Google Patents

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Publication number
RU2018141084A3
RU2018141084A3 RU2018141084A RU2018141084A RU2018141084A3 RU 2018141084 A3 RU2018141084 A3 RU 2018141084A3 RU 2018141084 A RU2018141084 A RU 2018141084A RU 2018141084 A RU2018141084 A RU 2018141084A RU 2018141084 A3 RU2018141084 A3 RU 2018141084A3
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RU
Russia
Application number
RU2018141084A
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RU2018141084A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Publication of RU2018141084A publication Critical patent/RU2018141084A/ru
Publication of RU2018141084A3 publication Critical patent/RU2018141084A3/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
RU2018141084A 2016-05-06 2017-05-05 Соединения тетрагидропиримидодиазепина и дигидропиридодиазепина для лечения боли и связанных с болью состояний RU2018141084A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16382199.4 2016-05-06
EP16382199 2016-05-06
PCT/EP2017/060780 WO2017191304A1 (en) 2016-05-06 2017-05-05 Tetrahydropyrimidodiazepine and tetrahydropyridodiazepine compounds for treating pain and pain related conditions

Publications (2)

Publication Number Publication Date
RU2018141084A RU2018141084A (ru) 2020-06-08
RU2018141084A3 true RU2018141084A3 (ru) 2020-06-11

Family

ID=56024209

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018141084A RU2018141084A (ru) 2016-05-06 2017-05-05 Соединения тетрагидропиримидодиазепина и дигидропиридодиазепина для лечения боли и связанных с болью состояний

Country Status (32)

Country Link
US (1) US10590140B2 (ru)
EP (1) EP3452475B1 (ru)
JP (1) JP6926197B2 (ru)
KR (1) KR20190024876A (ru)
CN (1) CN109526220B (ru)
AR (1) AR108387A1 (ru)
AU (1) AU2017260305B2 (ru)
BR (1) BR112018072755A2 (ru)
CA (1) CA3023379A1 (ru)
CO (1) CO2018012002A2 (ru)
CY (1) CY1123231T1 (ru)
DK (1) DK3452475T3 (ru)
ES (1) ES2789676T3 (ru)
HR (1) HRP20200668T1 (ru)
HU (1) HUE051829T2 (ru)
IL (1) IL262825A (ru)
LT (1) LT3452475T (ru)
ME (1) ME03726B (ru)
MX (1) MX2018013471A (ru)
MY (1) MY196791A (ru)
PH (1) PH12018502337A1 (ru)
PL (1) PL3452475T3 (ru)
PT (1) PT3452475T (ru)
RS (1) RS60528B1 (ru)
RU (1) RU2018141084A (ru)
SG (1) SG11201809799WA (ru)
SI (1) SI3452475T1 (ru)
TN (1) TN2018000372A1 (ru)
TW (1) TWI736619B (ru)
UA (1) UA123789C2 (ru)
WO (1) WO2017191304A1 (ru)
ZA (1) ZA201807653B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111225901B (zh) 2017-10-16 2023-07-04 埃斯特韦制药股份公司 用于治疗疼痛和与疼痛相关的病症的丙胺衍生物
MX2020003575A (es) * 2017-10-27 2020-07-22 Esteve Pharmaceuticals Sa Nuevos derivados de alcoxiamino para tratar dolor y estados relacionados con dolor.
TW201938154A (zh) * 2017-12-04 2019-10-01 西班牙商艾斯提夫製藥股份有限公司 具有抗疼痛活性之鄰苯氧基及鄰苄氧基丙胺基衍生物
WO2019115008A1 (en) * 2017-12-12 2019-06-20 Esteve Pharmaceuticals, S.A. Dialkylaminoarylpiperidinyl-o-phenoxy and o-benzyloxypropylamino derivatives having multimodal activity against pain
WO2019149919A1 (en) * 2018-02-05 2019-08-08 Esteve Pharmaceuticals, S.A. Aminopropoxypiperidinylamido derivatives having multimodal activity against pain
WO2020089263A1 (en) * 2018-10-31 2020-05-07 Esteve Pharmaceuticals, S.A. Optionally nitrogenated isoquinolin-1(2h)-ones and 1h-isochromen- 1-ones for treating pain and pain related conditions
JP2022509014A (ja) * 2018-11-02 2022-01-20 エステベ ファーマシューティカルズ,ソシエダッド アノニマ 疼痛及び疼痛に関連する状態を処置するための新規なアルコキシアミノピリジン誘導体
US20210395254A1 (en) * 2018-11-02 2021-12-23 Esteve Pharmaceuticals, S.A. New tetrahydropyrimidodiazepin and tetrahydropyridodiazepin compounds for treating pain and pain related conditions
EP3932912A4 (en) * 2019-02-28 2022-09-07 Osaka University MOLECULE FOR MODIFICATION BY A PROTEIN AND/OR A PEPTIDE

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03002649A (es) * 2000-09-27 2003-09-25 Ajinomoto Kk Derivado de benzodiazepina.
IL165593A0 (en) 2002-06-27 2006-01-15 Warner Lambert Co Use of an alpha2delta ligand such as gabapentin orpregabalin for treating attention deficit hyperac tivity disorder
US20070197510A1 (en) * 2004-03-10 2007-08-23 Kazuyuki Ohmoto Nitriles and medicinal compositions containing the same as the active ingredient
ES2351367T3 (es) * 2006-02-14 2011-02-03 Vertex Pharmaceuticals Incorporated Dihidrodiazepinas útiles como inhibidores de proteína quinasas.
TW200914457A (en) * 2007-05-31 2009-04-01 Kyowa Hakko Kogyo Kk Pyrimidodiazepinone derivative
UY32622A (es) * 2009-05-12 2010-12-31 Astrazeneca Ab Nuevos compuestos para el tratamiento de patologías relacionadas con ab(beta)

Also Published As

Publication number Publication date
JP6926197B2 (ja) 2021-08-25
TN2018000372A1 (en) 2020-06-15
EP3452475B1 (en) 2020-02-26
ES2789676T3 (es) 2020-10-26
TW201808955A (zh) 2018-03-16
ME03726B (me) 2021-01-20
CA3023379A1 (en) 2017-11-09
HRP20200668T1 (hr) 2020-10-16
PT3452475T (pt) 2020-05-05
SG11201809799WA (en) 2018-12-28
JP2019515039A (ja) 2019-06-06
WO2017191304A1 (en) 2017-11-09
LT3452475T (lt) 2020-05-11
CO2018012002A2 (es) 2019-04-30
AU2017260305A1 (en) 2018-12-13
CY1123231T1 (el) 2021-10-29
AU2017260305B2 (en) 2021-04-01
ZA201807653B (en) 2019-06-26
HUE051829T2 (hu) 2021-03-29
PH12018502337A1 (en) 2019-07-08
DK3452475T3 (da) 2020-04-27
KR20190024876A (ko) 2019-03-08
MY196791A (en) 2023-05-03
SI3452475T1 (sl) 2020-07-31
EP3452475A1 (en) 2019-03-13
TWI736619B (zh) 2021-08-21
RS60528B1 (sr) 2020-08-31
US10590140B2 (en) 2020-03-17
CN109526220A (zh) 2019-03-26
RU2018141084A (ru) 2020-06-08
UA123789C2 (uk) 2021-06-02
PL3452475T3 (pl) 2020-08-24
IL262825A (en) 2018-12-31
US20190144455A1 (en) 2019-05-16
BR112018072755A2 (pt) 2019-02-19
CN109526220B (zh) 2021-12-21
AR108387A1 (es) 2018-08-15
MX2018013471A (es) 2019-06-06

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