PL3452475T3 - Tetrahydropyrimidodiazepina i związki tetrahydropyridodiazepiny w leczeniu bólu i chorób związanych z bólem - Google Patents
Tetrahydropyrimidodiazepina i związki tetrahydropyridodiazepiny w leczeniu bólu i chorób związanych z bólemInfo
- Publication number
- PL3452475T3 PL3452475T3 PL17721680T PL17721680T PL3452475T3 PL 3452475 T3 PL3452475 T3 PL 3452475T3 PL 17721680 T PL17721680 T PL 17721680T PL 17721680 T PL17721680 T PL 17721680T PL 3452475 T3 PL3452475 T3 PL 3452475T3
- Authority
- PL
- Poland
- Prior art keywords
- pain
- tetrahydropyrimidodiazepine
- tetrahydropyridodiazepine
- compounds
- related conditions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16382199 | 2016-05-06 | ||
| PCT/EP2017/060780 WO2017191304A1 (en) | 2016-05-06 | 2017-05-05 | Tetrahydropyrimidodiazepine and tetrahydropyridodiazepine compounds for treating pain and pain related conditions |
| EP17721680.1A EP3452475B1 (en) | 2016-05-06 | 2017-05-05 | Tetrahydropyrimidodiazepine and tetrahydropyridodiazepine compounds for treating pain and pain related conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3452475T3 true PL3452475T3 (pl) | 2020-08-24 |
Family
ID=56024209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17721680T PL3452475T3 (pl) | 2016-05-06 | 2017-05-05 | Tetrahydropyrimidodiazepina i związki tetrahydropyridodiazepiny w leczeniu bólu i chorób związanych z bólem |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US10590140B2 (pl) |
| EP (1) | EP3452475B1 (pl) |
| JP (1) | JP6926197B2 (pl) |
| KR (1) | KR20190024876A (pl) |
| CN (1) | CN109526220B (pl) |
| AR (1) | AR108387A1 (pl) |
| AU (1) | AU2017260305B2 (pl) |
| BR (1) | BR112018072755A2 (pl) |
| CA (1) | CA3023379A1 (pl) |
| CO (1) | CO2018012002A2 (pl) |
| CY (1) | CY1123231T1 (pl) |
| DK (1) | DK3452475T3 (pl) |
| ES (1) | ES2789676T3 (pl) |
| HR (1) | HRP20200668T1 (pl) |
| HU (1) | HUE051829T2 (pl) |
| IL (1) | IL262825A (pl) |
| LT (1) | LT3452475T (pl) |
| ME (1) | ME03726B (pl) |
| MX (1) | MX2018013471A (pl) |
| MY (1) | MY196791A (pl) |
| PH (1) | PH12018502337A1 (pl) |
| PL (1) | PL3452475T3 (pl) |
| PT (1) | PT3452475T (pl) |
| RS (1) | RS60528B1 (pl) |
| RU (1) | RU2018141084A (pl) |
| SG (1) | SG11201809799WA (pl) |
| SI (1) | SI3452475T1 (pl) |
| TN (1) | TN2018000372A1 (pl) |
| TW (1) | TWI736619B (pl) |
| UA (1) | UA123789C2 (pl) |
| WO (1) | WO2017191304A1 (pl) |
| ZA (1) | ZA201807653B (pl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019076904A1 (en) * | 2017-10-16 | 2019-04-25 | Esteve Pharmaceuticals, S.A. | PROPANAMINE DERIVATIVES FOR THE TREATMENT OF PAIN AND PAIN DISEASES ASSOCIATED WITH PAIN |
| JP2021500416A (ja) * | 2017-10-27 | 2021-01-07 | エステベ ファーマスーティカルズ，ソシエダッド アノニマ | 疼痛及び疼痛関連状態を治療するための新規アルコキシアミノ誘導体 |
| AR113910A1 (es) * | 2017-12-04 | 2020-06-24 | Esteve Pharmaceuticals Sa | Derivados de o-fenoxi y o-benciloxipropilamino con actividad contra el dolor |
| WO2019115008A1 (en) * | 2017-12-12 | 2019-06-20 | Esteve Pharmaceuticals, S.A. | Dialkylaminoarylpiperidinyl-o-phenoxy and o-benzyloxypropylamino derivatives having multimodal activity against pain |
| WO2019149919A1 (en) * | 2018-02-05 | 2019-08-08 | Esteve Pharmaceuticals, S.A. | Aminopropoxypiperidinylamido derivatives having multimodal activity against pain |
| WO2020089263A1 (en) * | 2018-10-31 | 2020-05-07 | Esteve Pharmaceuticals, S.A. | Optionally nitrogenated isoquinolin-1(2h)-ones and 1h-isochromen- 1-ones for treating pain and pain related conditions |
| CN113166147A (zh) * | 2018-11-02 | 2021-07-23 | 埃斯特韦制药股份公司 | 用于治疗疼痛和疼痛相关病症的新的四氢嘧啶二氮杂卓和四氢吡啶二氮杂卓化合物 |
| TW202031264A (zh) * | 2018-11-02 | 2020-09-01 | 西班牙商埃斯特維製藥公司 | 用於治療疼痛和疼痛相關疾病的新穎烷氧基氨基吡啶衍生物 |
| WO2020175680A1 (ja) * | 2019-02-28 | 2020-09-03 | 国立大学法人大阪大学 | タンパク質及び／又はペプチド修飾用分子 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20030031196A (ko) * | 2000-09-27 | 2003-04-18 | 아지노모토 가부시키가이샤 | 벤조디아제핀 유도체 |
| CA2488566A1 (en) | 2002-06-27 | 2004-01-08 | Warner-Lambert Company Llc | Use of an alpha2delta ligand such as gabapentin or pregabalin for treating attention deficit hyperactivity disorder |
| JPWO2005085210A1 (ja) * | 2004-03-10 | 2008-01-17 | 小野薬品工業株式会社 | ニトリル化合物およびその化合物を有効成分として含有する医薬組成物 |
| ZA200806871B (en) * | 2006-02-14 | 2009-10-28 | Vertex Pharma | Dihydrodiazepines useful as inhibitors of protein kinases |
| TW200914457A (en) * | 2007-05-31 | 2009-04-01 | Kyowa Hakko Kogyo Kk | Pyrimidodiazepinone derivative |
| UY32622A (es) * | 2009-05-12 | 2010-12-31 | Astrazeneca Ab | Nuevos compuestos para el tratamiento de patologías relacionadas con ab(beta) |
-
2017
- 2017-05-05 TW TW106114980A patent/TWI736619B/zh not_active IP Right Cessation
- 2017-05-05 AR ARP170101172A patent/AR108387A1/es unknown
- 2017-05-05 AU AU2017260305A patent/AU2017260305B2/en not_active Ceased
- 2017-05-05 SG SG11201809799WA patent/SG11201809799WA/en unknown
- 2017-05-05 PT PT177216801T patent/PT3452475T/pt unknown
- 2017-05-05 RU RU2018141084A patent/RU2018141084A/ru unknown
- 2017-05-05 LT LTEP17721680.1T patent/LT3452475T/lt unknown
- 2017-05-05 MY MYPI2018704135A patent/MY196791A/en unknown
- 2017-05-05 HU HUE17721680A patent/HUE051829T2/hu unknown
- 2017-05-05 TN TNP/2018/000372A patent/TN2018000372A1/en unknown
- 2017-05-05 ES ES17721680T patent/ES2789676T3/es active Active
- 2017-05-05 SI SI201730239T patent/SI3452475T1/sl unknown
- 2017-05-05 PL PL17721680T patent/PL3452475T3/pl unknown
- 2017-05-05 JP JP2019510471A patent/JP6926197B2/ja active Active
- 2017-05-05 BR BR112018072755-5A patent/BR112018072755A2/pt not_active IP Right Cessation
- 2017-05-05 KR KR1020187032195A patent/KR20190024876A/ko not_active Application Discontinuation
- 2017-05-05 UA UAA201811326A patent/UA123789C2/uk unknown
- 2017-05-05 DK DK17721680.1T patent/DK3452475T3/da active
- 2017-05-05 EP EP17721680.1A patent/EP3452475B1/en active Active
- 2017-05-05 US US16/098,244 patent/US10590140B2/en active Active
- 2017-05-05 MX MX2018013471A patent/MX2018013471A/es unknown
- 2017-05-05 CA CA3023379A patent/CA3023379A1/en not_active Abandoned
- 2017-05-05 ME MEP-2020-101A patent/ME03726B/me unknown
- 2017-05-05 RS RS20200595A patent/RS60528B1/sr unknown
- 2017-05-05 WO PCT/EP2017/060780 patent/WO2017191304A1/en unknown
- 2017-05-05 CN CN201780042378.XA patent/CN109526220B/zh active Active
-
2018
- 2018-11-06 PH PH12018502337A patent/PH12018502337A1/en unknown
- 2018-11-06 IL IL262825A patent/IL262825A/en unknown
- 2018-11-14 ZA ZA2018/07653A patent/ZA201807653B/en unknown
- 2018-11-29 CO CONC2018/0012002A patent/CO2018012002A2/es unknown
-
2020
- 2020-04-26 HR HRP20200668TT patent/HRP20200668T1/hr unknown
- 2020-05-25 CY CY20201100472T patent/CY1123231T1/el unknown
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