SI3452475T1 - Tetrahidropirimidodiazepinske in tetrahidropiridodiazepinske spojine za zdravljenje bolečine in bolečinjskih stanj - Google Patents
Tetrahidropirimidodiazepinske in tetrahidropiridodiazepinske spojine za zdravljenje bolečine in bolečinjskih stanjInfo
- Publication number
- SI3452475T1 SI3452475T1 SI201730239T SI201730239T SI3452475T1 SI 3452475 T1 SI3452475 T1 SI 3452475T1 SI 201730239 T SI201730239 T SI 201730239T SI 201730239 T SI201730239 T SI 201730239T SI 3452475 T1 SI3452475 T1 SI 3452475T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pain
- tetrahydropyrimidodiazepine
- tetrahydropyridodiazepine
- compounds
- related conditions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16382199 | 2016-05-06 | ||
| PCT/EP2017/060780 WO2017191304A1 (en) | 2016-05-06 | 2017-05-05 | Tetrahydropyrimidodiazepine and tetrahydropyridodiazepine compounds for treating pain and pain related conditions |
| EP17721680.1A EP3452475B1 (en) | 2016-05-06 | 2017-05-05 | Tetrahydropyrimidodiazepine and tetrahydropyridodiazepine compounds for treating pain and pain related conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3452475T1 true SI3452475T1 (sl) | 2020-07-31 |
Family
ID=56024209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201730239T SI3452475T1 (sl) | 2016-05-06 | 2017-05-05 | Tetrahidropirimidodiazepinske in tetrahidropiridodiazepinske spojine za zdravljenje bolečine in bolečinjskih stanj |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US10590140B2 (sl) |
| EP (1) | EP3452475B1 (sl) |
| JP (1) | JP6926197B2 (sl) |
| KR (1) | KR20190024876A (sl) |
| CN (1) | CN109526220B (sl) |
| AR (1) | AR108387A1 (sl) |
| AU (1) | AU2017260305B2 (sl) |
| BR (1) | BR112018072755A2 (sl) |
| CA (1) | CA3023379A1 (sl) |
| CO (1) | CO2018012002A2 (sl) |
| CY (1) | CY1123231T1 (sl) |
| DK (1) | DK3452475T3 (sl) |
| ES (1) | ES2789676T3 (sl) |
| HR (1) | HRP20200668T1 (sl) |
| HU (1) | HUE051829T2 (sl) |
| IL (1) | IL262825A (sl) |
| LT (1) | LT3452475T (sl) |
| ME (1) | ME03726B (sl) |
| MX (1) | MX2018013471A (sl) |
| MY (1) | MY196791A (sl) |
| PH (1) | PH12018502337A1 (sl) |
| PL (1) | PL3452475T3 (sl) |
| PT (1) | PT3452475T (sl) |
| RS (1) | RS60528B1 (sl) |
| RU (1) | RU2018141084A (sl) |
| SG (1) | SG11201809799WA (sl) |
| SI (1) | SI3452475T1 (sl) |
| TN (1) | TN2018000372A1 (sl) |
| TW (1) | TWI736619B (sl) |
| UA (1) | UA123789C2 (sl) |
| WO (1) | WO2017191304A1 (sl) |
| ZA (1) | ZA201807653B (sl) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020536941A (ja) * | 2017-10-16 | 2020-12-17 | エステベ ファーマシューティカルズ, ソシエダッド アノニマEsteve Pharmaceuticals, S.A. | 疼痛及び疼痛に関連する状態を治療するためのプロパンアミン誘導体 |
| RU2020114523A (ru) * | 2017-10-27 | 2021-12-01 | Эстеве Фармасьютикалз, С.А. | Новые алкоксиаминопроизводные для лечения боли и связанных с болью состояний |
| WO2019110137A1 (en) * | 2017-12-04 | 2019-06-13 | Esteve Pharmaceuticals, S.A. | O-phenoxy and o-benzyloxypropylamino derivatives having activity against pain |
| WO2019115008A1 (en) * | 2017-12-12 | 2019-06-20 | Esteve Pharmaceuticals, S.A. | Dialkylaminoarylpiperidinyl-o-phenoxy and o-benzyloxypropylamino derivatives having multimodal activity against pain |
| WO2019149919A1 (en) * | 2018-02-05 | 2019-08-08 | Esteve Pharmaceuticals, S.A. | Aminopropoxypiperidinylamido derivatives having multimodal activity against pain |
| WO2020089263A1 (en) * | 2018-10-31 | 2020-05-07 | Esteve Pharmaceuticals, S.A. | Optionally nitrogenated isoquinolin-1(2h)-ones and 1h-isochromen- 1-ones for treating pain and pain related conditions |
| CN113166147A (zh) * | 2018-11-02 | 2021-07-23 | 埃斯特韦制药股份公司 | 用于治疗疼痛和疼痛相关病症的新的四氢嘧啶二氮杂卓和四氢吡啶二氮杂卓化合物 |
| WO2020089477A1 (en) * | 2018-11-02 | 2020-05-07 | Esteve Pharmaceuticals, S.A. | New alcoxyaminopyridine derivatives for treating pain and pain related conditions |
| JPWO2020175680A1 (sl) * | 2019-02-28 | 2020-09-03 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL362048A1 (en) * | 2000-09-27 | 2004-10-18 | Ajinomoto Co, Inc. | Benzodiazepine derivative |
| BR0312240A (pt) | 2002-06-27 | 2005-04-12 | Warner Lambert Co | Método de tratamento do distúrbio por déficit de atenção com hiperatividade |
| WO2005085210A1 (ja) * | 2004-03-10 | 2005-09-15 | Ono Pharmaceutical Co., Ltd. | ニトリル化合物およびその化合物を有効成分として含有する医薬組成物 |
| ES2351367T3 (es) * | 2006-02-14 | 2011-02-03 | Vertex Pharmaceuticals Incorporated | Dihidrodiazepinas útiles como inhibidores de proteína quinasas. |
| TW200914457A (en) * | 2007-05-31 | 2009-04-01 | Kyowa Hakko Kogyo Kk | Pyrimidodiazepinone derivative |
| UY32622A (es) * | 2009-05-12 | 2010-12-31 | Astrazeneca Ab | Nuevos compuestos para el tratamiento de patologías relacionadas con ab(beta) |
-
2017
- 2017-05-05 EP EP17721680.1A patent/EP3452475B1/en active Active
- 2017-05-05 RS RS20200595A patent/RS60528B1/sr unknown
- 2017-05-05 UA UAA201811326A patent/UA123789C2/uk unknown
- 2017-05-05 SG SG11201809799WA patent/SG11201809799WA/en unknown
- 2017-05-05 AR ARP170101172A patent/AR108387A1/es unknown
- 2017-05-05 MX MX2018013471A patent/MX2018013471A/es unknown
- 2017-05-05 WO PCT/EP2017/060780 patent/WO2017191304A1/en unknown
- 2017-05-05 JP JP2019510471A patent/JP6926197B2/ja active Active
- 2017-05-05 ES ES17721680T patent/ES2789676T3/es active Active
- 2017-05-05 LT LTEP17721680.1T patent/LT3452475T/lt unknown
- 2017-05-05 ME MEP-2020-101A patent/ME03726B/me unknown
- 2017-05-05 PL PL17721680T patent/PL3452475T3/pl unknown
- 2017-05-05 TW TW106114980A patent/TWI736619B/zh not_active IP Right Cessation
- 2017-05-05 DK DK17721680.1T patent/DK3452475T3/da active
- 2017-05-05 AU AU2017260305A patent/AU2017260305B2/en not_active Ceased
- 2017-05-05 RU RU2018141084A patent/RU2018141084A/ru unknown
- 2017-05-05 PT PT177216801T patent/PT3452475T/pt unknown
- 2017-05-05 TN TNP/2018/000372A patent/TN2018000372A1/en unknown
- 2017-05-05 CA CA3023379A patent/CA3023379A1/en not_active Abandoned
- 2017-05-05 BR BR112018072755-5A patent/BR112018072755A2/pt not_active IP Right Cessation
- 2017-05-05 SI SI201730239T patent/SI3452475T1/sl unknown
- 2017-05-05 MY MYPI2018704135A patent/MY196791A/en unknown
- 2017-05-05 HU HUE17721680A patent/HUE051829T2/hu unknown
- 2017-05-05 US US16/098,244 patent/US10590140B2/en active Active
- 2017-05-05 KR KR1020187032195A patent/KR20190024876A/ko not_active Application Discontinuation
- 2017-05-05 CN CN201780042378.XA patent/CN109526220B/zh active Active
-
2018
- 2018-11-06 PH PH12018502337A patent/PH12018502337A1/en unknown
- 2018-11-06 IL IL262825A patent/IL262825A/en unknown
- 2018-11-14 ZA ZA2018/07653A patent/ZA201807653B/en unknown
- 2018-11-29 CO CONC2018/0012002A patent/CO2018012002A2/es unknown
-
2020
- 2020-04-26 HR HRP20200668TT patent/HRP20200668T1/hr unknown
- 2020-05-25 CY CY20201100472T patent/CY1123231T1/el unknown
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