RU2018113716A3 - - Google Patents

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RU2018113716A3
RU2018113716A3 RU2018113716A RU2018113716A RU2018113716A3 RU 2018113716 A3 RU2018113716 A3 RU 2018113716A3 RU 2018113716 A RU2018113716 A RU 2018113716A RU 2018113716 A RU2018113716 A RU 2018113716A RU 2018113716 A3 RU2018113716 A3 RU 2018113716A3
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RU2018113716A
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RU2747644C2 (ru
RU2018113716A (ru
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
RU2018113716A 2015-09-23 2016-09-22 Бигетероарил-замещенные 1,4-бензодиазепины и пути их применения для лечения рака RU2747644C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15186478 2015-09-23
EP15186478.2 2015-09-23
PCT/EP2016/072501 WO2017050865A1 (en) 2015-09-23 2016-09-22 Bi-heteroaryl substituted 1,4-benzodiazepines and uses thereof for the treatment of cancer

Publications (3)

Publication Number Publication Date
RU2018113716A RU2018113716A (ru) 2019-10-24
RU2018113716A3 true RU2018113716A3 (ru) 2020-01-22
RU2747644C2 RU2747644C2 (ru) 2021-05-11

Family

ID=54251305

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018113716A RU2747644C2 (ru) 2015-09-23 2016-09-22 Бигетероарил-замещенные 1,4-бензодиазепины и пути их применения для лечения рака

Country Status (17)

Country Link
US (2) US11542247B2 (ru)
EP (1) EP3353164B1 (ru)
JP (1) JP6896711B2 (ru)
KR (1) KR20180052631A (ru)
CN (1) CN108137546B (ru)
AU (1) AU2016328693B2 (ru)
BR (1) BR112018005625B1 (ru)
CA (1) CA2996989C (ru)
DK (1) DK3353164T3 (ru)
ES (1) ES2904513T3 (ru)
HR (1) HRP20220012T1 (ru)
HU (1) HUE057090T2 (ru)
LT (1) LT3353164T (ru)
MX (1) MX2018003564A (ru)
RU (1) RU2747644C2 (ru)
SI (1) SI3353164T1 (ru)
WO (1) WO2017050865A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4132646A1 (en) * 2020-04-08 2023-02-15 Remix Therapeutics Inc. Compounds and methods for modulating splicing

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