RU2016139287A3 - - Google Patents
Download PDFInfo
- Publication number
- RU2016139287A3 RU2016139287A3 RU2016139287A RU2016139287A RU2016139287A3 RU 2016139287 A3 RU2016139287 A3 RU 2016139287A3 RU 2016139287 A RU2016139287 A RU 2016139287A RU 2016139287 A RU2016139287 A RU 2016139287A RU 2016139287 A3 RU2016139287 A3 RU 2016139287A3
- Authority
- RU
- Russia
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N25/00—Investigating or analyzing materials by the use of thermal means
- G01N25/02—Investigating or analyzing materials by the use of thermal means by investigating changes of state or changes of phase; by investigating sintering
- G01N25/04—Investigating or analyzing materials by the use of thermal means by investigating changes of state or changes of phase; by investigating sintering of melting point; of freezing point; of softening point
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/101—Temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2561/00—Nucleic acid detection characterised by assay method
- C12Q2561/113—Real time assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20140037310 | 2014-03-28 | ||
| KR10-2014-0037310 | 2014-03-28 | ||
| US201461979545P | 2014-04-15 | 2014-04-15 | |
| US61/979,545 | 2014-04-15 | ||
| KRPCT/KR2014/004173 | 2014-05-09 | ||
| PCT/KR2014/004173 WO2015147370A1 (en) | 2014-03-28 | 2014-05-09 | Detection of target nucleic acid sequences using different detection temperatures |
| KRPCT/KR2014/006714 | 2014-07-23 | ||
| PCT/KR2014/006714 WO2015147382A1 (en) | 2014-03-28 | 2014-07-23 | Detection of target nucleic acid sequences using different detection temperatures |
| PCT/KR2014/012074 WO2015147412A1 (en) | 2014-03-28 | 2014-12-09 | Detection of target nucleic acid sequences using different detection temperatures |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019100495A Division RU2780587C2 (ru) | 2014-03-28 | 2014-12-09 | Детекция нуклеотидных последовательностей-мишеней с использованием разных температур детекции |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2016139287A RU2016139287A (ru) | 2018-05-03 |
| RU2016139287A3 true RU2016139287A3 (ru) | 2018-05-03 |
| RU2678403C2 RU2678403C2 (ru) | 2019-01-28 |
Family
ID=54195861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016139287A RU2678403C2 (ru) | 2014-03-28 | 2014-12-09 | Детекция нуклеотидных последовательностей-мишеней с использованием разных температур детекции |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US10752938B2 (ru) |
| EP (3) | EP3122896B1 (ru) |
| JP (1) | JP6620110B2 (ru) |
| KR (6) | KR102509130B1 (ru) |
| CN (3) | CN106103740A (ru) |
| AU (2) | AU2014387732B2 (ru) |
| BR (1) | BR112016021782B1 (ru) |
| CA (1) | CA2941880C (ru) |
| DK (1) | DK3122897T3 (ru) |
| ES (1) | ES2964624T3 (ru) |
| FI (1) | FI3122897T3 (ru) |
| IL (1) | IL248034B (ru) |
| MX (1) | MX2016012508A (ru) |
| MY (1) | MY181022A (ru) |
| NZ (1) | NZ725593A (ru) |
| PL (1) | PL3122897T3 (ru) |
| PT (1) | PT3122897T (ru) |
| RU (1) | RU2678403C2 (ru) |
| SA (1) | SA516371903B1 (ru) |
| SG (1) | SG11201607510QA (ru) |
| WO (4) | WO2015147370A1 (ru) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102145677B1 (ko) | 2012-02-03 | 2020-08-18 | 캘리포니아 인스티튜트 오브 테크놀로지 | 다중화된 생화학적 분석에서의 시그널 인코딩 및 디코딩 |
| US9791372B2 (en) | 2012-08-03 | 2017-10-17 | California Institute Of Technology | Multiplexing and quantification in PCR with reduced hardware and requirements |
| WO2015147370A1 (en) * | 2014-03-28 | 2015-10-01 | Seegene, Inc. | Detection of target nucleic acid sequences using different detection temperatures |
| WO2016093620A1 (en) * | 2014-12-09 | 2016-06-16 | Seegene, Inc. | Differentiation of signals for target nucleic acid sequences |
| EP3230474A4 (en) * | 2014-12-09 | 2018-04-25 | Seegene, Inc. | Detection of target nucleic acid sequences using different detection temperatures and reference values |
| EP3390665B1 (en) * | 2015-12-15 | 2023-12-06 | Seegene, Inc. | Signal extraction for a target nucleic acid sequence |
| WO2017131463A1 (en) * | 2016-01-26 | 2017-08-03 | Seegene, Inc. . | Methods for providing signal for target nucleic acid sequence |
| EP4219519A3 (en) * | 2016-04-01 | 2023-09-13 | Chromacode, Inc. | Competitive probes for engineering signal generation |
| KR102468174B1 (ko) | 2016-09-15 | 2022-11-17 | 에프. 호프만-라 로슈 아게 | 멀티플렉스 pcr 수행 방법 |
| KR102408564B1 (ko) * | 2017-03-28 | 2022-06-14 | 주식회사 씨젠 | 타겟 핵산 서열의 존재를 결정하기 위한 분석 시그널 |
| KR102380264B1 (ko) * | 2017-08-31 | 2022-03-29 | 주식회사 씨젠 | 다이머-형성 프라이머 쌍을 이용한 구성요소의 성능 평가 |
| WO2019135567A1 (en) | 2018-01-05 | 2019-07-11 | Seegene, Inc. . | Method for determining the presence or absence of m. tuberculosis, m. bovis and m. bovis bcg in a sample |
| CN111629831A (zh) * | 2018-01-22 | 2020-09-04 | 卢米耐克斯公司 | 用于离散解链分析的方法和组合物 |
| US20210040542A1 (en) * | 2018-04-20 | 2021-02-11 | Seegene, Inc. | Method And Apparatus For Detecting A Plurality Of Target Nucleic Acid Sequences In Sample |
| WO2020218831A1 (ko) * | 2019-04-22 | 2020-10-29 | 포항공과대학교 산학협력단 | 신규한 등온 단일 반응용 프로브 세트 및 이의 용도 |
| JP7353396B2 (ja) | 2019-06-14 | 2023-09-29 | シージーン アイエヌシー | ターゲット核酸検出用試薬の協業開発のためのコンピュータ処理方法 |
| KR102107589B1 (ko) | 2019-11-20 | 2020-05-07 | 주식회사 유진셀 | 단일 신호 형광 물질을 이용한 실시간 타겟 핵산 검출 및 정량 방법 |
| KR20220108959A (ko) | 2021-01-28 | 2022-08-04 | 주식회사 엘지에너지솔루션 | 리튬-황 전지용 전해액 및 이를 포함하는 리튬-황 전지 |
| IL309407A (en) * | 2021-06-17 | 2024-02-01 | Seegene Inc | Detection of multiple target nucleic acids using multiple temperature detection |
| WO2023023533A1 (en) * | 2021-08-19 | 2023-02-23 | Luminex Corporation | Digital amplification assay analysis method |
| WO2023068823A1 (ko) | 2021-10-21 | 2023-04-27 | 주식회사 씨젠 | 시료 내 표적 분석물질에 대한 양음성 판독 장치 및 방법 |
| WO2023195780A1 (en) * | 2022-04-08 | 2023-10-12 | Seegene, Inc. | Method for detecting three target nucleic acids in sample |
| WO2024010351A1 (ko) * | 2022-07-05 | 2024-01-11 | 주식회사 씨젠 | 복수의 표적 분석물 각각에 대한 근사 신호의 획득 방법 및 이를 수행하는 컴퓨터 장치 |
| WO2024080818A1 (ko) * | 2022-10-14 | 2024-04-18 | 주식회사 씨젠 | 상이한 tm 값을 가지는 2개의 프로브를 이용하여 샘플 내 타겟 핵산을 검출하는 방법 |
Family Cites Families (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4351760A (en) | 1979-09-07 | 1982-09-28 | Syva Company | Novel alkyl substituted fluorescent compounds and polyamino acid conjugates |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| ATE138106T1 (de) | 1988-07-20 | 1996-06-15 | David Segev | Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen |
| CA2020958C (en) | 1989-07-11 | 2005-01-11 | Daniel L. Kacian | Nucleic acid sequence amplification methods |
| US5427930A (en) | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
| CA2035010C (en) | 1990-01-26 | 1996-12-10 | Keith C. Backman | Method of amplifying target nucleic acids applicable to both polymerase and ligase chain reactions |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US5965364A (en) | 1990-10-09 | 1999-10-12 | Benner; Steven Albert | Method for selecting functional deoxyribonucleotide derivatives |
| US5432272A (en) | 1990-10-09 | 1995-07-11 | Benner; Steven A. | Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases |
| US6037120A (en) | 1995-10-12 | 2000-03-14 | Benner; Steven Albert | Recognition of oligonucleotides containing non-standard base pairs |
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| US5556751A (en) | 1991-04-25 | 1996-09-17 | Amoco Corporation | Selective amplification system using Q-β replicase |
| JPH06153997A (ja) * | 1992-11-27 | 1994-06-03 | Canon Inc | 検出信号増幅による標的核酸の検出方法 |
| US5541311A (en) | 1992-12-07 | 1996-07-30 | Third Wave Technologies, Inc. | Nucleic acid encoding synthesis-deficient thermostable DNA polymerase |
| CA2170264A1 (en) | 1993-09-10 | 1995-03-16 | Michael W. Konrad | Optical detection of position of oligonucleotides on large dna molecules |
| US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| EP1736554B1 (en) * | 1996-05-29 | 2013-10-09 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions |
| US6174670B1 (en) | 1996-06-04 | 2001-01-16 | University Of Utah Research Foundation | Monitoring amplification of DNA during PCR |
| US6117635A (en) | 1996-07-16 | 2000-09-12 | Intergen Company | Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon |
| US6194149B1 (en) | 1998-03-03 | 2001-02-27 | Third Wave Technologies, Inc. | Target-dependent reactions using structure-bridging oligonucleotides |
| US6031098A (en) * | 1997-08-11 | 2000-02-29 | California Institute Of Technology | Detection and treatment of duplex polynucleotide damage |
| GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
| WO2000063365A1 (en) | 1999-04-21 | 2000-10-26 | Pangene Corporation | Locked nucleic acid hybrids and methods of use |
| US7537886B1 (en) | 1999-06-22 | 2009-05-26 | Life Technologies Corporation | Primers and methods for the detection and discrimination of nucleic acids |
| WO2001073118A2 (en) | 2000-03-29 | 2001-10-04 | Lgc (Teddington) Limited | Hybridisation beacon and method of rapid sequence detection and discrimination |
| WO2001077392A2 (en) * | 2000-04-10 | 2001-10-18 | Matthew Ashby | Methods for the survey and genetic analysis of populations |
| WO2001090417A2 (en) | 2000-05-19 | 2001-11-29 | Eragen Biosciences, Inc. | Materials and methods for detection of nucleic acids |
| US6350580B1 (en) * | 2000-10-11 | 2002-02-26 | Stratagene | Methods for detection of a target nucleic acid using a probe comprising secondary structure |
| US7309573B2 (en) | 2000-11-21 | 2007-12-18 | Stratagene California | Methods for detection of a nucleic acid by sequential amplification |
| CA2500129C (en) * | 2002-09-30 | 2011-03-29 | F. Hoffmann-La Roche Ag | Oligonucleotides for genotyping thymidylate synthase gene |
| ATE289685T1 (de) * | 2003-08-25 | 2005-03-15 | Mtm Lab Ag | Verfahren zum nachweis von karzinomen in solubilisierten zervikalen körperproben |
| US20050053950A1 (en) * | 2003-09-08 | 2005-03-10 | Enrique Zudaire Ubani | Protocol and software for multiplex real-time PCR quantification based on the different melting temperatures of amplicons |
| JP2007512811A (ja) * | 2003-11-10 | 2007-05-24 | インベスチゲン， インコーポレイテッド | 検出のための核酸を調製する方法 |
| US8407013B2 (en) * | 2005-06-07 | 2013-03-26 | Peter K. Rogan | AB initio generation of single copy genomic probes |
| CA2623268C (en) * | 2005-09-20 | 2021-12-14 | University Of Utah Research Foundation | Melting curve analysis with exponential background subtraction |
| CN102171366B (zh) * | 2008-07-31 | 2014-11-26 | 奥西泰克有限公司 | 多重扩增与检测 |
| BRPI0917434A2 (pt) * | 2008-08-08 | 2015-12-01 | Smiths Detection Inc | algoritmo de detecçao para ensaio de pcr |
| JP5509075B2 (ja) * | 2008-12-16 | 2014-06-04 | アークレイ株式会社 | 核酸増幅のコントロールの検出方法およびその用途 |
| US8039215B2 (en) * | 2009-03-10 | 2011-10-18 | Roche Molecular Systems, Inc. | Multiplex quantitative nucleic acid amplification and melting assay |
| EP2480689A4 (en) | 2009-09-24 | 2013-05-15 | Seegene Inc | DETECTION OF TARGET NUCLEIC ACID SEQUENCES USING CYCLIC EXONUCLEOLYTIC REACTIONS |
| WO2011078441A1 (en) | 2009-12-21 | 2011-06-30 | Seegene, Inc. | Tsg primer target detection |
| JP5901046B2 (ja) * | 2010-02-19 | 2016-04-06 | 国立大学法人 千葉大学 | ＯＡＴＰ１Ｂ３ｍＲＮＡの新規な選択的スプライシングバリアント |
| WO2012048207A2 (en) | 2010-10-07 | 2012-04-12 | Brandeis University | Compositions and methods for nucleic acid based diagnostic assays |
| GB201017978D0 (en) * | 2010-10-25 | 2010-12-08 | Oxitec Ltd | Multiplex amplification and detection |
| MX340258B (es) | 2011-01-11 | 2016-07-01 | Seegene Inc | Detección de secuencias de ácido nucleico objetivo mediante ensayo de escisión y extensión del pto. |
| WO2012126639A1 (en) * | 2011-03-24 | 2012-09-27 | Qiagen Gmbh | Modified hybridization probes |
| US11078525B2 (en) * | 2011-03-29 | 2021-08-03 | Seegene, Inc. | Detection of target nucleic acid sequence by PTO cleavage and extension-dependent cleavage |
| KR20130101952A (ko) | 2012-02-02 | 2013-09-16 | 주식회사 씨젠 | Ｐｔｏ 절단과 연장-의존적 혼성화를 이용한 타겟 핵산서열의 검출 |
| JP5976849B2 (ja) * | 2012-03-05 | 2016-08-24 | シージーン アイエヌシー | ＰＴＯ切断及び伸長アッセイによるターゲット核酸配列でのヌクレオチド変異検出｛ＤｅｔｅｃｔｉｏｎｏｆＮｕｃｌｅｏｔｉｄｅＶａｒｉａｔｉｏｎｏｎＴａｒｇｅｔＮｕｃｌｅｉｃＡｃｉｄＳｅｑｕｅｎｃｅｂｙＰＴＯＣｌｅａｖａｇｅａｎｄＥｘｔｅｎｓｉｏｎＡｓｓａｙ｝ |
| US9791372B2 (en) | 2012-08-03 | 2017-10-17 | California Institute Of Technology | Multiplexing and quantification in PCR with reduced hardware and requirements |
| WO2015147370A1 (en) * | 2014-03-28 | 2015-10-01 | Seegene, Inc. | Detection of target nucleic acid sequences using different detection temperatures |
| DE102014105129B3 (de) * | 2014-04-10 | 2015-07-02 | Kist Europe-Korea Institute of Science and Technologie Europe Forschungsgesellschaft mbh | Verfahren und Master-Mix für die quantitative Echtzeit-PCR für Multiplex-Ziel-Nukleinsäuremoleküle |
| WO2016093620A1 (en) * | 2014-12-09 | 2016-06-16 | Seegene, Inc. | Differentiation of signals for target nucleic acid sequences |
| WO2018044831A1 (en) * | 2016-08-30 | 2018-03-08 | Integrated Dna Technologies, Inc. | Cleavable hairpin primers |
-
2014
- 2014-05-09 WO PCT/KR2014/004173 patent/WO2015147370A1/en active Application Filing
- 2014-06-17 US US15/124,700 patent/US10752938B2/en active Active
- 2014-06-17 EP EP14886915.9A patent/EP3122896B1/en active Active
- 2014-06-17 WO PCT/KR2014/005309 patent/WO2015147377A1/en active Application Filing
- 2014-07-23 WO PCT/KR2014/006714 patent/WO2015147382A1/en active Application Filing
- 2014-12-09 KR KR1020227003377A patent/KR102509130B1/ko active IP Right Grant
- 2014-12-09 FI FIEP14887573.5T patent/FI3122897T3/fi active
- 2014-12-09 BR BR112016021782-9A patent/BR112016021782B1/pt active IP Right Grant
- 2014-12-09 EP EP14887573.5A patent/EP3122897B1/en active Active
- 2014-12-09 SG SG11201607510QA patent/SG11201607510QA/en unknown
- 2014-12-09 MY MYPI2016703229A patent/MY181022A/en unknown
- 2014-12-09 KR KR1020227034325A patent/KR102604951B1/ko active IP Right Grant
- 2014-12-09 JP JP2016556868A patent/JP6620110B2/ja active Active
- 2014-12-09 CN CN201480077317.3A patent/CN106103740A/zh active Pending
- 2014-12-09 KR KR1020187007421A patent/KR102016748B1/ko active IP Right Grant
- 2014-12-09 NZ NZ725593A patent/NZ725593A/en unknown
- 2014-12-09 US US15/124,977 patent/US20170247750A1/en active Pending
- 2014-12-09 ES ES14887573T patent/ES2964624T3/es active Active
- 2014-12-09 AU AU2014387732A patent/AU2014387732B2/en active Active
- 2014-12-09 KR KR1020197034833A patent/KR102210548B1/ko active IP Right Grant
- 2014-12-09 DK DK14887573.5T patent/DK3122897T3/da active
- 2014-12-09 EP EP23190117.4A patent/EP4269607A3/en active Pending
- 2014-12-09 KR KR1020217002697A patent/KR102358734B1/ko active IP Right Grant
- 2014-12-09 WO PCT/KR2014/012074 patent/WO2015147412A1/en active Application Filing
- 2014-12-09 CA CA2941880A patent/CA2941880C/en active Active
- 2014-12-09 KR KR1020167029473A patent/KR102050601B1/ko active IP Right Grant
- 2014-12-09 RU RU2016139287A patent/RU2678403C2/ru active
- 2014-12-09 CN CN202010806475.5A patent/CN111893171A/zh active Pending
- 2014-12-09 CN CN201910807436.4A patent/CN110452962A/zh active Pending
- 2014-12-09 MX MX2016012508A patent/MX2016012508A/es unknown
- 2014-12-09 PT PT148875735T patent/PT3122897T/pt unknown
- 2014-12-09 PL PL14887573.5T patent/PL3122897T3/pl unknown
-
2016
- 2016-09-26 SA SA516371903A patent/SA516371903B1/ar unknown
- 2016-09-26 IL IL248034A patent/IL248034B/en unknown
-
2018
- 2018-06-27 AU AU2018204665A patent/AU2018204665B2/en active Active
-
2020
- 2020-07-17 US US16/931,545 patent/US20200340043A1/en not_active Abandoned