RU2015147106A - Пробиотические штаммы для применения в лечении или профилактике остеопороза - Google Patents
Пробиотические штаммы для применения в лечении или профилактике остеопороза Download PDFInfo
- Publication number
- RU2015147106A RU2015147106A RU2015147106A RU2015147106A RU2015147106A RU 2015147106 A RU2015147106 A RU 2015147106A RU 2015147106 A RU2015147106 A RU 2015147106A RU 2015147106 A RU2015147106 A RU 2015147106A RU 2015147106 A RU2015147106 A RU 2015147106A
- Authority
- RU
- Russia
- Prior art keywords
- dsm
- use according
- lactobacillus plantarum
- prevention
- treatment
- Prior art date
Links
- 239000006041 probiotic Substances 0.000 title claims 7
- 230000000529 probiotic effect Effects 0.000 title claims 7
- 235000018291 probiotics Nutrition 0.000 title claims 7
- 208000001132 Osteoporosis Diseases 0.000 title claims 4
- 230000002265 prevention Effects 0.000 title claims 4
- 240000006024 Lactobacillus plantarum Species 0.000 claims 7
- 235000013965 Lactobacillus plantarum Nutrition 0.000 claims 7
- 229940072205 lactobacillus plantarum Drugs 0.000 claims 7
- 241000186605 Lactobacillus paracasei Species 0.000 claims 5
- 210000000988 bone and bone Anatomy 0.000 claims 2
- 235000013305 food Nutrition 0.000 claims 2
- 239000000047 product Substances 0.000 claims 2
- 208000006386 Bone Resorption Diseases 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 claims 1
- 230000024279 bone resorption Effects 0.000 claims 1
- 230000001054 cortical effect Effects 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- 235000013376 functional food Nutrition 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- 230000009245 menopause Effects 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 235000008935 nutritious Nutrition 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/306—Foods, ingredients or supplements having a functional effect on health having an effect on bone mass, e.g. osteoporosis prevention
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
- C12R2001/25—Lactobacillus plantarum
Claims (9)
1. Применение, по меньшей мере, одного пробиотического штамма, выбранного из Lactobacillus paracasei, или, по меньшей мере, одного пробиотического штамма, выбранного из Lactobacillus paracasei в комбинации, по меньшей мере, с одним пробиотическим штаммом, выбранным из Lactobacillus plantarum, для лечения или профилактики остеопороза, или для повышения абсорбции ионов Ca2+ у млекопитающего, предпочтительно у человека.
2. Применение по п. 1 для лечения или профилактики остеопороза путем предотвращения потери кортикальной костной ткани, потери минеральной плотности кости и резорбции кости.
3. Применение по п. 1, где указанный по меньшей мере один пробиотический штамм Lactobacillus paracasei выбран из Lactobacillus paracasei 8700:2, DSM 13434 и Lactobacillus paracasei 02:A, DSM 13432.
4. Применение по п. 1, где указанный, по меньшей мере, один пробиотический штамм Lactobacillus plantarum выбран из Lactobacillus plantarum 299, DSM 6595, Lactobacillus plantarum 299v, DSM 9843, Lactobacillus plantarum HEAL 9, DSM 15312, Lactobacillus plantarum HEAL 19, DSM 15313 и Lactobacillus plantarum HEAL 99, DSM 15316.
5. Применение по п. 1, где указанный, по меньшей мере, один пробиотический штамм(ы) присутствует в композиции, содержащей дополнительно, по меньшей мере, один носитель.
6. Применение по п. 5, где указанная композиция содержит Ca2+ в количестве 80-320 мг, предпочтительно 120-240 мг.
7. Применение по п. 5 или 6, где указанная композиция выбрана из группы, состоящей из продукта питания, пищевой добавки, медицинского продукта питания, функционального продукта питания и питательного продукта.
8. Применение по п. 3 или 4, где указанный штамм(ы) присутствует в количестве примерно от 1×106 до 1×1014 КОЕ, предпочтительно от 1×108 до 1×1012 и более предпочтительно от 1×109 до 1×1011.
9. Применение по любому из пп. 1-6 для лечения или профилактики остеопороза, связанного с менопаузой.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1350414-7 | 2013-04-03 | ||
| SE1350414 | 2013-04-03 | ||
| SE1351571 | 2013-12-20 | ||
| SE1351571-3 | 2013-12-20 | ||
| PCT/SE2014/050399 WO2014163568A1 (en) | 2013-04-03 | 2014-04-03 | Probiotic strains for use in treatment or prevention of osteoporosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2015147106A true RU2015147106A (ru) | 2017-05-05 |
| RU2636027C2 RU2636027C2 (ru) | 2017-11-17 |
Family
ID=51659047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015147106A RU2636027C2 (ru) | 2013-04-03 | 2014-04-03 | Пробиотические штаммы для применения в лечении или профилактике остеопороза |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US10245290B2 (ru) |
| EP (1) | EP2981274B1 (ru) |
| JP (1) | JP6103675B2 (ru) |
| KR (2) | KR102000514B1 (ru) |
| CN (3) | CN117064923A (ru) |
| AU (1) | AU2014250113B2 (ru) |
| CA (1) | CA2908051C (ru) |
| DK (1) | DK2981274T3 (ru) |
| ES (1) | ES2804615T3 (ru) |
| HK (1) | HK1220129A1 (ru) |
| HR (1) | HRP20201139T1 (ru) |
| MX (1) | MX371418B (ru) |
| NZ (1) | NZ712959A (ru) |
| PL (1) | PL2981274T3 (ru) |
| PT (1) | PT2981274T (ru) |
| RS (1) | RS60527B1 (ru) |
| RU (1) | RU2636027C2 (ru) |
| WO (1) | WO2014163568A1 (ru) |
| ZA (1) | ZA201507275B (ru) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018030837A1 (ko) * | 2016-08-12 | 2018-02-15 | 한국식품연구원 | 락토바실러스 아시도필루스를 포함하는 갱년기 예방 또는 치료용 조성물 |
| KR101867768B1 (ko) | 2016-08-12 | 2018-06-15 | 한국식품연구원 | 락토바실러스 아시도필루스를 포함하는 갱년기 예방 또는 치료용 조성물 |
| CN106858605A (zh) * | 2016-12-26 | 2017-06-20 | 吉林舒润生物科技有限公司 | 一种用于预防及治疗骨吸收相关疾病的益生菌钙功能食品 |
| CN110177561B (zh) * | 2017-01-12 | 2023-09-12 | 普罗比公司 | 益生菌组合物和其用途 |
| TWI604052B (zh) * | 2017-02-20 | 2017-11-01 | 景岳生物科技股份有限公司 | 促進骨質再生的植物乳桿菌菌株ｇｍｎｌ－６６２及其組合物 |
| TWI607759B (zh) * | 2017-07-07 | 2017-12-11 | 景岳生物科技股份有限公司 | 副乾酪乳桿菌菌株ｇｍｎｌ－６５３用於製備抗骨質流失的組合物的用途 |
| TWI607758B (zh) * | 2017-03-07 | 2017-12-11 | 景岳生物科技股份有限公司 | 改善乾癬症狀的副乾酪乳桿菌菌株ｇｍｎｌ－６５３及其組合物 |
| CN108567800A (zh) * | 2017-03-07 | 2018-09-25 | 景岳生物科技股份有限公司 | 副干酪乳杆菌菌株gmnl-653用于制备抗骨质流失的组合物的用途 |
| CN108624520B (zh) * | 2017-03-16 | 2022-01-25 | 景岳生物科技股份有限公司 | 促进骨质再生的植物乳杆菌菌株gmnl-662及其组合物 |
| JP6964191B2 (ja) * | 2017-11-02 | 2021-11-10 | ユニバーシティ−インダストリー コーオペレイション グループ オブ キョンヒ ユニバーシティUniversity−Industry Cooperation Group Of Kyung Hee University | 新規な乳酸菌およびその使用 |
| CN108030096A (zh) * | 2017-12-18 | 2018-05-15 | 浙江民生健康科技有限公司 | 一种钙铁锌与益生菌组合物及其应用 |
| BR112020015599A2 (pt) * | 2018-02-02 | 2021-01-05 | Kobiolabs, Inc. | Cepa de lactobacillus plantarum kbl396 e uso da mesma |
| TWI664910B (zh) * | 2018-04-24 | 2019-07-11 | 葡萄王生技股份有限公司 | 乳酸桿菌屬、其醫藥組合物及可食用組合物於治療、預防或改善骨質疾病的用途 |
| BR112020026032A2 (pt) * | 2018-06-18 | 2021-03-23 | Probi Ab | composições probióticas e usos das mesmas |
| KR102107443B1 (ko) * | 2018-08-31 | 2020-05-07 | (주)바이오리듬 | 여성 갱년기 증상 예방 또는 치료용 유산균 프로바이오틱스 제제 |
| WO2020051379A1 (en) * | 2018-09-05 | 2020-03-12 | Solarea Bio, Inc. | Methods and compositions for treating musculoskeletal diseases |
| KR102120479B1 (ko) * | 2018-10-30 | 2020-06-09 | 주식회사 종근당바이오 | 프로바이오틱스를 유효 성분으로 포함하는 이차성 골다공증의 예방 또는 치료용 조성물 |
| GB201905386D0 (en) | 2019-04-16 | 2019-05-29 | Probi Ab | Probiotic compositions and uses thereof |
| CN111109607A (zh) * | 2020-01-10 | 2020-05-08 | 青岛康益生物科技有限公司 | 一种用于预防和治疗骨质疏松症的健康食品 |
| CN111718903A (zh) * | 2020-06-24 | 2020-09-29 | 江南大学 | 一种筛选可预防和/或治疗骨质疏松的药物的方法 |
| CN111621449B (zh) * | 2020-07-02 | 2022-07-12 | 安徽善和生物科技有限公司 | 一种益生菌及其在继发性骨质疏松中的应用 |
| TWI770811B (zh) * | 2021-02-05 | 2022-07-11 | 國立臺灣大學 | 一種益生菌、其組合物及用途 |
| TWI802194B (zh) * | 2021-07-13 | 2023-05-11 | 大江生醫股份有限公司 | 諾麗果發酵物於製備改善體態及肌膚狀況之組合物之用途 |
| WO2023092150A1 (en) | 2021-11-22 | 2023-05-25 | Solarea Bio, Inc. | Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause |
| CN114634901B (zh) * | 2022-05-18 | 2022-08-30 | 微康益生菌(苏州)股份有限公司 | 一种促进骨骼健康的干酪乳杆菌lc16及其培养方法与应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2214258C2 (ru) | 1997-07-05 | 2003-10-20 | Сосьете Де Продюи Нестле С.А. | Всасывание минеральных веществ кишечными клетками |
| GB9920578D0 (en) * | 1999-08-31 | 1999-11-03 | Nestle Sa | Composition for maintenance of bone or dental health or treatment of bone or dental disorders |
| SE0003100D0 (sv) | 2000-09-01 | 2000-09-01 | Probi Ab | New strains |
| SE529199C2 (sv) * | 2005-07-05 | 2007-05-29 | Probi Ab | Förstärkt absorption |
| CN1927010A (zh) * | 2005-09-06 | 2007-03-14 | 天津科技大学 | 具有增加骨密度、抑制血管紧张素转化酶功能的无乳糖发酵大豆乳及其制备方法 |
| WO2007040445A1 (en) | 2005-10-06 | 2007-04-12 | Probi Ab | Use of lactobacillus for treatment of virus infections |
| JP2009114111A (ja) * | 2007-11-06 | 2009-05-28 | Tsujido Kagaku Kk | カルシウム吸収促進剤 |
| JP2009114112A (ja) | 2007-11-06 | 2009-05-28 | Tsujido Kagaku Kk | 抗骨粗鬆症剤 |
| JP2009144111A (ja) * | 2007-12-18 | 2009-07-02 | Kansai Paint Co Ltd | 塗料組成物及び塗膜形成方法 |
| SE533778C2 (sv) * | 2009-05-14 | 2011-01-11 | Probi Ab | Probiotisk fruktdryck |
| KR101279852B1 (ko) * | 2011-06-29 | 2013-07-09 | 주식회사 쎌바이오텍 | 골다공증 예방 또는 치료용 조성물 |
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2014
- 2014-04-03 CN CN202310826128.2A patent/CN117064923A/zh active Pending
- 2014-04-03 CN CN201480020011.4A patent/CN105188723A/zh active Pending
- 2014-04-03 KR KR1020157030629A patent/KR102000514B1/ko active IP Right Grant
- 2014-04-03 JP JP2016506288A patent/JP6103675B2/ja active Active
- 2014-04-03 NZ NZ712959A patent/NZ712959A/en unknown
- 2014-04-03 EP EP14779522.3A patent/EP2981274B1/en active Active
- 2014-04-03 WO PCT/SE2014/050399 patent/WO2014163568A1/en active Application Filing
- 2014-04-03 PL PL14779522T patent/PL2981274T3/pl unknown
- 2014-04-03 AU AU2014250113A patent/AU2014250113B2/en active Active
- 2014-04-03 US US14/782,138 patent/US10245290B2/en active Active
- 2014-04-03 RU RU2015147106A patent/RU2636027C2/ru active
- 2014-04-03 MX MX2015014016A patent/MX371418B/es active IP Right Grant
- 2014-04-03 KR KR1020177036076A patent/KR102129934B1/ko active IP Right Grant
- 2014-04-03 RS RS20200844A patent/RS60527B1/sr unknown
- 2014-04-03 DK DK14779522.3T patent/DK2981274T3/da active
- 2014-04-03 ES ES14779522T patent/ES2804615T3/es active Active
- 2014-04-03 CA CA2908051A patent/CA2908051C/en active Active
- 2014-04-03 PT PT147795223T patent/PT2981274T/pt unknown
- 2014-04-03 CN CN202310824073.1A patent/CN116889579A/zh active Pending
-
2015
- 2015-10-01 ZA ZA2015/07275A patent/ZA201507275B/en unknown
-
2016
- 2016-07-13 HK HK16108237.8A patent/HK1220129A1/zh unknown
-
2020
- 2020-07-20 HR HRP20201139TT patent/HRP20201139T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2981274B1 (en) | 2020-05-06 |
| HRP20201139T1 (hr) | 2020-10-30 |
| CN117064923A (zh) | 2023-11-17 |
| CA2908051A1 (en) | 2014-10-09 |
| JP2016521123A (ja) | 2016-07-21 |
| HK1220129A1 (zh) | 2017-04-28 |
| KR102129934B1 (ko) | 2020-07-03 |
| NZ712959A (en) | 2017-01-27 |
| BR112015025256A8 (pt) | 2021-09-14 |
| KR20170141820A (ko) | 2017-12-26 |
| EP2981274A4 (en) | 2017-03-01 |
| CN105188723A (zh) | 2015-12-23 |
| BR112015025256A2 (pt) | 2017-07-18 |
| CA2908051C (en) | 2021-03-02 |
| US20160067289A1 (en) | 2016-03-10 |
| MX2015014016A (es) | 2016-06-24 |
| JP6103675B2 (ja) | 2017-03-29 |
| DK2981274T3 (da) | 2020-07-06 |
| AU2014250113B2 (en) | 2017-03-30 |
| PT2981274T (pt) | 2020-07-13 |
| MX371418B (es) | 2020-01-29 |
| US10245290B2 (en) | 2019-04-02 |
| AU2014250113A1 (en) | 2015-10-29 |
| ZA201507275B (en) | 2022-03-30 |
| RS60527B1 (sr) | 2020-08-31 |
| CN116889579A (zh) | 2023-10-17 |
| EP2981274A1 (en) | 2016-02-10 |
| KR102000514B1 (ko) | 2019-10-01 |
| WO2014163568A1 (en) | 2014-10-09 |
| ES2804615T3 (es) | 2021-02-08 |
| RU2636027C2 (ru) | 2017-11-17 |
| PL2981274T3 (pl) | 2020-12-28 |
| KR20150133284A (ko) | 2015-11-27 |
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