RU2014141180A3 - - Google Patents

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Publication number
RU2014141180A3
RU2014141180A3 RU2014141180A RU2014141180A RU2014141180A3 RU 2014141180 A3 RU2014141180 A3 RU 2014141180A3 RU 2014141180 A RU2014141180 A RU 2014141180A RU 2014141180 A RU2014141180 A RU 2014141180A RU 2014141180 A3 RU2014141180 A3 RU 2014141180A3
Authority
RU
Russia
Application number
RU2014141180A
Other languages
Russian (ru)
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RU2677324C2 (ru
RU2014141180A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2014141180A publication Critical patent/RU2014141180A/ru
Publication of RU2014141180A3 publication Critical patent/RU2014141180A3/ru
Application granted granted Critical
Publication of RU2677324C2 publication Critical patent/RU2677324C2/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
RU2014141180A 2008-11-07 2014-10-13 Новое лечение острого лимфобластного лейкоза у детей RU2677324C2 (ru)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US11232308P 2008-11-07 2008-11-07
US61/112,323 2008-11-07
US18329109P 2009-06-02 2009-06-02
US61/183,291 2009-06-02
US22126909P 2009-06-29 2009-06-29
US61/221,269 2009-06-29

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU2011122827/10A Division RU2536933C2 (ru) 2008-11-07 2009-11-06 Новое лечение острого лимфобластного лейкоза у детей

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2018144313A Division RU2736802C2 (ru) 2008-11-07 2018-12-14 Новое лечение острого лимфобластного лейкоза у детей

Publications (3)

Publication Number Publication Date
RU2014141180A RU2014141180A (ru) 2016-05-10
RU2014141180A3 true RU2014141180A3 (enExample) 2018-06-09
RU2677324C2 RU2677324C2 (ru) 2019-01-16

Family

ID=41796119

Family Applications (3)

Application Number Title Priority Date Filing Date
RU2011122827/10A RU2536933C2 (ru) 2008-11-07 2009-11-06 Новое лечение острого лимфобластного лейкоза у детей
RU2014141180A RU2677324C2 (ru) 2008-11-07 2014-10-13 Новое лечение острого лимфобластного лейкоза у детей
RU2018144313A RU2736802C2 (ru) 2008-11-07 2018-12-14 Новое лечение острого лимфобластного лейкоза у детей

Family Applications Before (1)

Application Number Title Priority Date Filing Date
RU2011122827/10A RU2536933C2 (ru) 2008-11-07 2009-11-06 Новое лечение острого лимфобластного лейкоза у детей

Family Applications After (1)

Application Number Title Priority Date Filing Date
RU2018144313A RU2736802C2 (ru) 2008-11-07 2018-12-14 Новое лечение острого лимфобластного лейкоза у детей

Country Status (27)

Country Link
US (2) US20110262440A1 (enExample)
EP (4) EP3330293B1 (enExample)
JP (2) JP5798036B2 (enExample)
KR (1) KR101695329B1 (enExample)
CN (2) CN102209729B (enExample)
AU (1) AU2009313039B2 (enExample)
BR (1) BRPI0921341A2 (enExample)
CA (1) CA2742242C (enExample)
CY (3) CY1116160T1 (enExample)
DK (3) DK2344539T3 (enExample)
ES (3) ES2662929T3 (enExample)
HK (1) HK1255590B (enExample)
HR (3) HRP20150400T1 (enExample)
HU (3) HUE025452T2 (enExample)
IL (1) IL212651A (enExample)
LT (2) LT3330293T (enExample)
MX (1) MX2011002931A (enExample)
NO (1) NO2918604T3 (enExample)
NZ (1) NZ591312A (enExample)
PL (3) PL2344539T3 (enExample)
PT (3) PT3330293T (enExample)
RS (3) RS59348B1 (enExample)
RU (3) RU2536933C2 (enExample)
SG (1) SG195549A1 (enExample)
SI (3) SI3330293T1 (enExample)
SM (3) SMT201900546T1 (enExample)
WO (1) WO2010052013A1 (enExample)

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JOP20200236A1 (ar) 2012-09-21 2017-06-16 Regeneron Pharma الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
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TWI682941B (zh) 2013-02-01 2020-01-21 美商再生元醫藥公司 含嵌合恆定區之抗體
CN103131777A (zh) * 2013-02-05 2013-06-05 南京艾迪康医学检验所有限公司 用于检测e2a-pbx融合基因相对表达量的试剂盒
EP3105252B1 (en) 2014-02-12 2019-07-24 Michael Uhlin Bispecific antibodies for use in stem cell transplantation
TWI754319B (zh) 2014-03-19 2022-02-01 美商再生元醫藥公司 用於腫瘤治療之方法及抗體組成物
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US20170252364A1 (en) 2014-07-30 2017-09-07 Mor Research Applications Ltd. Compositions for treatment of acute lymphoblastic leukemia and methods of use thereof
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ES2809455T3 (es) 2014-11-17 2021-03-04 Regeneron Pharma Métodos para tratamiento tumoral usando anticuerpo biespecífico CD3xCD20
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DK3277725T3 (da) 2015-03-30 2021-01-11 Regeneron Pharma Konstante tungkædeområder med reduceret binding til FC-gammareceptorer
PL3280729T3 (pl) 2015-04-08 2022-08-22 Novartis Ag Terapie cd20, terapie cd22 i terapie skojarzone komórką eksprymującą chimeryczny receptor antygenowy (car) cd19
SI3298042T1 (sl) 2015-05-20 2025-03-31 Amgen Research (Munich) Gmbh Deplecija B celic kot diagnostični marker
MY195059A (en) 2015-09-23 2023-01-05 Regeneron Pharma Optimized Anti-CD3 Bispecific Antibodies and Uses Thereof
CN108602889A (zh) * 2015-12-22 2018-09-28 瑞泽恩制药公司 医治急性成淋巴细胞性白血病的双特异性抗cd20/抗cd3抗体
GB201602974D0 (en) * 2016-02-19 2016-04-06 Clube Jasper R Engineered cells & methods (1)
EP3430052A2 (en) * 2016-03-14 2019-01-23 Millennium Pharmaceuticals, Inc. Method of preventing graft versus host disease
WO2017214207A2 (en) * 2016-06-06 2017-12-14 Juno Therapeutics, Inc. Methods for the treatment of b cell malignancies using adoptive cell therapy
US11590167B2 (en) 2016-12-03 2023-02-28 Juno Therapeutic, Inc. Methods and compositions for use of therapeutic T cells in combination with kinase inhibitors
MA48763A (fr) * 2017-05-05 2020-04-08 Amgen Inc Composition pharmaceutique comprenant des constructions d'anticorps bispécifiques pour un stockage et une administration améliorés
IL327498A (en) 2017-06-02 2026-05-01 Juno Therapeutics Inc Articles of manufacture and methods for treatment using adoptive cell therapy
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KR102083481B1 (ko) 2018-03-22 2020-03-02 강원대학교산학협력단 아연-키토산 나노 입자를 포함한 급성 림프구성 백혈병 치료용 약학조성물
ES3009025T3 (en) 2018-08-31 2025-03-25 Regeneron Pharma Dosing strategy that mitigates cytokine release syndrome for cd3/cd20 bispecific antibodies
AU2020214336B2 (en) * 2019-01-30 2026-06-04 The Wistar Institute Of Anatomy And Biology DNA-encoded bispecific T-cell engagers targeting cancer antigens and methods of use in cancer theraputics
JP7137696B2 (ja) 2019-05-14 2022-09-14 プロヴェンション・バイオ・インコーポレイテッド 1型糖尿病を予防するための方法および組成物
AU2020279224B2 (en) 2019-05-21 2024-12-05 Novartis Ag Trispecific binding molecules against BCMA and uses thereof
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JP6881658B2 (ja) 2019-07-05 2021-06-02 小野薬品工業株式会社 Pd−1/cd3二重特異性タンパク質による血液がん治療
KR20230092863A (ko) 2020-06-11 2023-06-26 프로벤션 바이오, 인코포레이티드 제1형 당뇨병을 예방하기 위한 방법 및 조성물
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JP5798036B2 (ja) * 2008-11-07 2015-10-21 アムゲン リサーチ (ミュンヘン) ゲーエムベーハー 小児急性リンパ芽球性白血病の新規治療
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Also Published As

Publication number Publication date
HUE036922T2 (hu) 2018-08-28
PT3330293T (pt) 2019-10-18
CN102209729A (zh) 2011-10-05
RS59348B1 (sr) 2019-10-31
CY1122428T1 (el) 2021-01-27
PL3330293T3 (pl) 2020-02-28
RU2677324C2 (ru) 2019-01-16
HRP20180426T1 (hr) 2018-04-20
RU2018144313A (ru) 2020-06-15
SI3330293T1 (sl) 2019-10-30
DK2918604T3 (en) 2018-03-19
CA2742242A1 (en) 2010-05-14
PT2344539E (pt) 2015-04-01
RU2736802C2 (ru) 2020-11-20
EP2344539A1 (en) 2011-07-20
DK3330293T3 (da) 2019-10-07
HUE025452T2 (en) 2016-05-30
ES2535257T3 (es) 2015-05-07
CN102209729B (zh) 2016-05-25
CY1116160T1 (el) 2017-02-08
PL2918604T3 (pl) 2018-05-30
AU2009313039A1 (en) 2010-05-14
EP3330293B1 (en) 2019-07-24
HUE046222T2 (hu) 2020-02-28
SI2918604T1 (en) 2018-04-30
JP2012508163A (ja) 2012-04-05
US20230235053A1 (en) 2023-07-27
EP2918604B1 (en) 2017-12-20
RS53980B1 (sr) 2015-10-30
NZ591312A (en) 2012-09-28
SMT201800149T1 (it) 2018-05-02
KR101695329B1 (ko) 2017-01-23
WO2010052013A1 (en) 2010-05-14
BRPI0921341A2 (pt) 2016-04-26
ES2662929T3 (es) 2018-04-10
US20110262440A1 (en) 2011-10-27
AU2009313039B2 (en) 2015-06-18
HRP20191715T1 (hr) 2019-12-13
SG195549A1 (en) 2013-12-30
IL212651A (en) 2015-03-31
EP2918604A1 (en) 2015-09-16
JP2015232023A (ja) 2015-12-24
CY1120022T1 (el) 2018-12-12
HK1255590B (en) 2020-07-10
RU2014141180A (ru) 2016-05-10
RS56989B1 (sr) 2018-05-31
LT3330293T (lt) 2019-10-10
NO2918604T3 (enExample) 2018-05-19
HK1215258A1 (en) 2016-08-19
SMT201900546T1 (it) 2019-11-13
MX2011002931A (es) 2011-04-11
CA2742242C (en) 2023-01-10
CN106390114A (zh) 2017-02-15
HK1158667A1 (en) 2012-07-20
ES2748126T3 (es) 2020-03-13
EP3330293A1 (en) 2018-06-06
RU2018144313A3 (enExample) 2020-06-15
HRP20150400T1 (hr) 2015-05-08
PL2344539T3 (pl) 2015-07-31
LT2918604T (lt) 2018-03-26
DK2344539T3 (en) 2015-05-04
KR20110091669A (ko) 2011-08-12
PT2918604T (pt) 2018-03-02
EP2344539B1 (en) 2015-02-11
RU2536933C2 (ru) 2014-12-27
IL212651A0 (en) 2011-07-31
EP3594237A1 (en) 2020-01-15
SI2344539T1 (sl) 2015-06-30
SMT201500104B (it) 2015-07-09
JP5798036B2 (ja) 2015-10-21
JP6130451B2 (ja) 2017-05-17
RU2011122827A (ru) 2012-12-20

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