RU2011135422A - Человеческие анти-il-6 антитела с пролонгированным периодом выведения in vivo и их применение при лечении онкологических, аутоиммунных заболеваний и воспалительных заболеваний - Google Patents

Человеческие анти-il-6 антитела с пролонгированным периодом выведения in vivo и их применение при лечении онкологических, аутоиммунных заболеваний и воспалительных заболеваний Download PDF

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RU2011135422A
RU2011135422A RU2011135422/10A RU2011135422A RU2011135422A RU 2011135422 A RU2011135422 A RU 2011135422A RU 2011135422/10 A RU2011135422/10 A RU 2011135422/10A RU 2011135422 A RU2011135422 A RU 2011135422A RU 2011135422 A RU2011135422 A RU 2011135422A
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amino acid
substitutions
seq
acid residues
antibody
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RU2011135422/10A
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Майкл БОУЭН
Херрен ВУ
Вильям ДАЛЛЬ'АКВА
Питер КИНЕР
Бахия ДЖАЛЛАЛ
Антони КОЙЛ
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Медиммун, Ллк
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
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RU2011135422/10A 2009-01-29 2010-01-29 Человеческие анти-il-6 антитела с пролонгированным периодом выведения in vivo и их применение при лечении онкологических, аутоиммунных заболеваний и воспалительных заболеваний RU2011135422A (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14810609P 2009-01-29 2009-01-29
US61/148,106 2009-01-29
US18418209P 2009-06-04 2009-06-04
US61/184,182 2009-06-04
PCT/US2010/022478 WO2010088444A1 (en) 2009-01-29 2010-01-29 Human anti-il-6 antibodies with extended in vivo half-life and their use in treatment of oncology, autoimmune diseases and inflammatory diseases

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RU2015150249A Division RU2650594C1 (ru) 2009-01-29 2010-01-29 Человеческие анти-il-6 антитела с пролонгированным периодом выведения in vivo и их применение при лечении онкологических, аутоиммунных заболеваний и воспалительных заболеваний

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RU2011135422A true RU2011135422A (ru) 2013-03-10

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RU2015150249A RU2650594C1 (ru) 2009-01-29 2010-01-29 Человеческие анти-il-6 антитела с пролонгированным периодом выведения in vivo и их применение при лечении онкологических, аутоиммунных заболеваний и воспалительных заболеваний

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US (3) US20120034212A1 (enExample)
EP (1) EP2391384A4 (enExample)
JP (3) JP2012516158A (enExample)
KR (1) KR20110108398A (enExample)
CN (2) CN102387814A (enExample)
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RU (2) RU2011135422A (enExample)
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