RU2010141213A - Ингибитор эластазы - Google Patents

Ингибитор эластазы Download PDF

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Publication number
RU2010141213A
RU2010141213A RU2010141213/15A RU2010141213A RU2010141213A RU 2010141213 A RU2010141213 A RU 2010141213A RU 2010141213/15 A RU2010141213/15 A RU 2010141213/15A RU 2010141213 A RU2010141213 A RU 2010141213A RU 2010141213 A RU2010141213 A RU 2010141213A
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RU
Russia
Prior art keywords
elastase inhibitor
hydroxyproline
inhibitor according
composition
skin
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RU2010141213/15A
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English (en)
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RU2548794C2 (ru
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Масато ИИНО
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Сисейдо Компани, Лтд.
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Publication of RU2010141213A publication Critical patent/RU2010141213A/ru
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Publication of RU2548794C2 publication Critical patent/RU2548794C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

1. Ингибитор эластазы, содержащий в качестве его активных ингредиентов экстракт малины и гидроксипролин.2. Ингибитор эластазы по п.1, в котором гидроксипролин представляет собой L- гидроксипролин.3. Ингибитор эластазы по п.1 или 2, дополнительно содержащий дрожжевой экстракт.4. Ингибитор эластазы по п.3, в котором дрожжевой экстракт получают из дрожжей, которые культивировались в питательной среде, содержащей гликозаминогликан, и которые подвергали ультрафиолетовому облучению, обработке перекисью водорода или и тому и другому воздействию.5. Композиция для наружного применения на коже, содержащая ингибитор эластазы по любому из пп.1-4.6. Композиция для наружного применения на коже по п.5, которая представляет собой косметическое средство.

Claims (6)

1. Ингибитор эластазы, содержащий в качестве его активных ингредиентов экстракт малины и гидроксипролин.
2. Ингибитор эластазы по п.1, в котором гидроксипролин представляет собой L- гидроксипролин.
3. Ингибитор эластазы по п.1 или 2, дополнительно содержащий дрожжевой экстракт.
4. Ингибитор эластазы по п.3, в котором дрожжевой экстракт получают из дрожжей, которые культивировались в питательной среде, содержащей гликозаминогликан, и которые подвергали ультрафиолетовому облучению, обработке перекисью водорода или и тому и другому воздействию.
5. Композиция для наружного применения на коже, содержащая ингибитор эластазы по любому из пп.1-4.
6. Композиция для наружного применения на коже по п.5, которая представляет собой косметическое средство.
RU2010141213/15A 2010-08-06 2010-08-06 Ингибитор эластазы RU2548794C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2010/063414 WO2012017555A1 (ja) 2010-08-06 2010-08-06 エラスターゼ阻害剤

Publications (2)

Publication Number Publication Date
RU2010141213A true RU2010141213A (ru) 2014-09-20
RU2548794C2 RU2548794C2 (ru) 2015-04-20

Family

ID=45556326

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2010141213/15A RU2548794C2 (ru) 2010-08-06 2010-08-06 Ингибитор эластазы

Country Status (8)

Country Link
US (1) US8491946B2 (ru)
EP (1) EP2601959B1 (ru)
JP (1) JP5725864B2 (ru)
KR (1) KR101736503B1 (ru)
CN (1) CN102438641B (ru)
HK (1) HK1168761A1 (ru)
RU (1) RU2548794C2 (ru)
WO (1) WO2012017555A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11458157B2 (en) 2011-12-16 2022-10-04 Targetgene Biotechnologies Ltd. Compositions and methods for modifying a predetermined target nucleic acid sequence
CN108498404A (zh) * 2018-05-29 2018-09-07 华中农业大学 一种具有美白功能的树莓提取物
KR20230062700A (ko) 2021-10-29 2023-05-09 공주대학교 산학협력단 엘라스타아제 저해 활성을 갖는 퀴놀린 유도체 화합물, 그의 제조방법 및 그의 용도

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Also Published As

Publication number Publication date
EP2601959B1 (en) 2018-11-21
JPWO2012017555A1 (ja) 2013-09-19
EP2601959A1 (en) 2013-06-12
KR20130041399A (ko) 2013-04-25
WO2012017555A1 (ja) 2012-02-09
KR101736503B1 (ko) 2017-05-16
EP2601959A4 (en) 2014-06-11
RU2548794C2 (ru) 2015-04-20
CN102438641A (zh) 2012-05-02
HK1168761A1 (zh) 2013-01-11
CN102438641B (zh) 2015-11-25
US8491946B2 (en) 2013-07-23
US20120034260A1 (en) 2012-02-09
JP5725864B2 (ja) 2015-05-27

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