RU2009107707A - СПЕЦИФИЧНОЕ К EphB3 АНТИТЕЛО И ЕГО ПРИМЕНЕНИЕ - Google Patents

СПЕЦИФИЧНОЕ К EphB3 АНТИТЕЛО И ЕГО ПРИМЕНЕНИЕ Download PDF

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Publication number
RU2009107707A
RU2009107707A RU2009107707/10A RU2009107707A RU2009107707A RU 2009107707 A RU2009107707 A RU 2009107707A RU 2009107707/10 A RU2009107707/10 A RU 2009107707/10A RU 2009107707 A RU2009107707 A RU 2009107707A RU 2009107707 A RU2009107707 A RU 2009107707A
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RU
Russia
Prior art keywords
antibody
xpa
xna
хна
ephb3
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RU2009107707/10A
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English (en)
Russian (ru)
Inventor
Джефф ХСУ (US)
Джефф ХСУ
Линда МАСАТ (US)
Линда Масат
Джуди АБРАХАМ (US)
Джуди АБРАХАМ
Масахиса ХАНДА (US)
Масахиса ХАНДА
Сью ШЕЙЕР (US)
Сью ШЕЙЕР
Original Assignee
Новартис АГ (CH)
Новартис Аг
Ксома Текнолоджи Лтд. (Us)
Ксома Текнолоджи Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Новартис АГ (CH), Новартис Аг, Ксома Текнолоджи Лтд. (Us), Ксома Текнолоджи Лтд. filed Critical Новартис АГ (CH)
Publication of RU2009107707A publication Critical patent/RU2009107707A/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2009107707/10A 2006-08-04 2007-08-03 СПЕЦИФИЧНОЕ К EphB3 АНТИТЕЛО И ЕГО ПРИМЕНЕНИЕ RU2009107707A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83577706P 2006-08-04 2006-08-04
US60/835,777 2006-08-04

Publications (1)

Publication Number Publication Date
RU2009107707A true RU2009107707A (ru) 2010-09-10

Family

ID=39033597

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009107707/10A RU2009107707A (ru) 2006-08-04 2007-08-03 СПЕЦИФИЧНОЕ К EphB3 АНТИТЕЛО И ЕГО ПРИМЕНЕНИЕ

Country Status (11)

Country Link
US (2) US8586716B2 (cg-RX-API-DMAC7.html)
EP (2) EP2057193B1 (cg-RX-API-DMAC7.html)
JP (2) JP5406027B2 (cg-RX-API-DMAC7.html)
KR (2) KR20140033236A (cg-RX-API-DMAC7.html)
CN (1) CN101626783A (cg-RX-API-DMAC7.html)
BR (1) BRPI0715332A2 (cg-RX-API-DMAC7.html)
CA (1) CA2659820A1 (cg-RX-API-DMAC7.html)
ES (1) ES2452067T3 (cg-RX-API-DMAC7.html)
MX (1) MX2009001341A (cg-RX-API-DMAC7.html)
RU (1) RU2009107707A (cg-RX-API-DMAC7.html)
WO (1) WO2008019326A2 (cg-RX-API-DMAC7.html)

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US9354170B2 (en) 2011-02-15 2016-05-31 University Of Calcutta NIR fluorescence of heavy water
UA114902C2 (uk) 2011-12-20 2017-08-28 Янссен Байотек, Інк. Виділене антитіло, яке зв'язує парний спіральний філамент-тау (псф-тау), та фармацевтична композиція, що містить таке антитіло
EA201890158A1 (ru) * 2015-06-30 2018-06-29 Сиэтл Дженетикс, Инк. Антитела против ntb-a и связанные композиции и способы
JOP20180021A1 (ar) 2017-03-16 2019-01-30 Janssen Biotech Inc الأجسام المضادة لتكتلات خيوط بروتين تاو (tau) الحلزونية المزدوجة واستخداماتها
KR102055350B1 (ko) * 2017-09-28 2019-12-13 고려대학교 산학협력단 대장암의 항암제 내성 진단용 바이오마커 및 이의 용도
US12234280B2 (en) 2018-03-05 2025-02-25 Janssen Pharmaceutica Nv Anti-PHF-tau antibodies and uses thereof
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CN119735674A (zh) * 2024-12-06 2025-04-01 合肥综合性国家科学中心大健康研究院 抗vmat2的抗体或其抗原结合片段及其组合物和应用

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Publication number Publication date
KR20090039799A (ko) 2009-04-22
JP5406027B2 (ja) 2014-02-05
JP2013153769A (ja) 2013-08-15
WO2008019326A2 (en) 2008-02-14
EP2420252A1 (en) 2012-02-22
JP2010500006A (ja) 2010-01-07
WO2008019326A3 (en) 2008-05-02
EP2057193B1 (en) 2013-12-18
ES2452067T3 (es) 2014-03-31
US9006398B2 (en) 2015-04-14
CN101626783A (zh) 2010-01-13
US8586716B2 (en) 2013-11-19
CA2659820A1 (en) 2008-02-14
EP2057193A2 (en) 2009-05-13
BRPI0715332A2 (pt) 2013-10-08
KR101437188B1 (ko) 2014-10-02
US20090142261A1 (en) 2009-06-04
MX2009001341A (es) 2009-05-28
KR20140033236A (ko) 2014-03-17
AU2007281717A1 (en) 2008-02-14
US20140148584A1 (en) 2014-05-29

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