RU2009101298A - Гетероциклические соединения в качестве усилителей подслащивающего вещества - Google Patents
Гетероциклические соединения в качестве усилителей подслащивающего вещества Download PDFInfo
- Publication number
- RU2009101298A RU2009101298A RU2009101298/21A RU2009101298A RU2009101298A RU 2009101298 A RU2009101298 A RU 2009101298A RU 2009101298/21 A RU2009101298/21 A RU 2009101298/21A RU 2009101298 A RU2009101298 A RU 2009101298A RU 2009101298 A RU2009101298 A RU 2009101298A
- Authority
- RU
- Russia
- Prior art keywords
- alkyl
- optionally substituted
- hydrogen
- absent
- represents hydrogen
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 65
- 239000001257 hydrogen Substances 0.000 claims abstract 63
- 150000001875 compounds Chemical class 0.000 claims abstract 25
- 229910052717 sulfur Inorganic materials 0.000 claims abstract 25
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims abstract 21
- 229910052799 carbon Inorganic materials 0.000 claims abstract 19
- 229910052760 oxygen Inorganic materials 0.000 claims abstract 19
- 125000003118 aryl group Chemical group 0.000 claims abstract 15
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract 13
- 125000006577 C1-C6 hydroxyalkyl group Chemical group 0.000 claims abstract 12
- 125000003342 alkenyl group Chemical group 0.000 claims abstract 9
- 229910052736 halogen Inorganic materials 0.000 claims abstract 7
- 150000002367 halogens Chemical class 0.000 claims abstract 7
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract 6
- 235000009508 confectionery Nutrition 0.000 claims abstract 6
- 125000000623 heterocyclic group Chemical group 0.000 claims abstract 6
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims abstract 4
- 150000003839 salts Chemical class 0.000 claims abstract 4
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 claims abstract 3
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims abstract 3
- 125000006708 (C5-C14) heteroaryl group Chemical group 0.000 claims abstract 3
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical class NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 claims abstract 3
- 125000004663 dialkyl amino group Chemical group 0.000 claims abstract 3
- 125000005553 heteroaryloxy group Chemical group 0.000 claims abstract 3
- 125000005368 heteroarylthio group Chemical group 0.000 claims abstract 3
- 125000005842 heteroatom Chemical group 0.000 claims abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims abstract 3
- 230000002708 enhancing effect Effects 0.000 claims abstract 2
- 235000019605 sweet taste sensations Nutrition 0.000 claims abstract 2
- 125000000217 alkyl group Chemical group 0.000 claims 65
- 150000002431 hydrogen Chemical class 0.000 claims 27
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 15
- 229910052757 nitrogen Inorganic materials 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 7
- 125000001072 heteroaryl group Chemical group 0.000 claims 5
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 125000003107 substituted aryl group Chemical group 0.000 claims 4
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 claims 2
- -1 2,6-dimethoxyphenoxy Chemical group 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 235000013305 food Nutrition 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000001424 substituent group Chemical group 0.000 claims 2
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 claims 2
- 125000006570 (C5-C6) heteroaryl group Chemical group 0.000 claims 1
- DHFVWJLZKXODRA-UHFFFAOYSA-N 2-(2-imino-1,3-thiazol-3-yl)-1-(3-nitrophenyl)ethanone Chemical compound [O-][N+](=O)C1=CC=CC(C(=O)CN2C(SC=C2)=N)=C1 DHFVWJLZKXODRA-UHFFFAOYSA-N 0.000 claims 1
- BDLLDQBFNYGYTQ-UHFFFAOYSA-N 2-(3-chloro-2-methoxyphenyl)imidazo[1,2-a]pyridine Chemical compound COC1=C(Cl)C=CC=C1C1=CN(C=CC=C2)C2=N1 BDLLDQBFNYGYTQ-UHFFFAOYSA-N 0.000 claims 1
- MWPZHSQYGBSDAP-UHFFFAOYSA-N 2-[2-(2-methoxyphenoxy)ethylsulfanyl]-1h-benzimidazole Chemical compound COC1=CC=CC=C1OCCSC1=NC2=CC=CC=C2N1 MWPZHSQYGBSDAP-UHFFFAOYSA-N 0.000 claims 1
- CAAMSDWKXXPUJR-UHFFFAOYSA-N 3,5-dihydro-4H-imidazol-4-one Chemical compound O=C1CNC=N1 CAAMSDWKXXPUJR-UHFFFAOYSA-N 0.000 claims 1
- LKYXJCHSNRKXFW-UHFFFAOYSA-N 3-benzyl-5-(4-methyl-1,3-thiazol-2-yl)-1-propan-2-ylpyrimidine-2,4-dione Chemical compound O=C1N(CC=2C=CC=CC=2)C(=O)N(C(C)C)C=C1C1=NC(C)=CS1 LKYXJCHSNRKXFW-UHFFFAOYSA-N 0.000 claims 1
- NSPMIYGKQJPBQR-UHFFFAOYSA-N 4H-1,2,4-triazole Chemical compound C=1N=CNN=1 NSPMIYGKQJPBQR-UHFFFAOYSA-N 0.000 claims 1
- CADIORXBYWCRLK-UHFFFAOYSA-N 5,5-dimethyl-1-oxido-2,4-diphenylimidazol-1-ium Chemical compound [O-][N+]=1C(C)(C)C(C=2C=CC=CC=2)=NC=1C1=CC=CC=C1 CADIORXBYWCRLK-UHFFFAOYSA-N 0.000 claims 1
- ARNKONOSMZFURP-UHFFFAOYSA-N 5-chloro-1-methyl-3-(trifluoromethyl)-n-[4-(trifluoromethyl)phenyl]pyrazole-4-carboxamide Chemical compound CN1N=C(C(F)(F)F)C(C(=O)NC=2C=CC(=CC=2)C(F)(F)F)=C1Cl ARNKONOSMZFURP-UHFFFAOYSA-N 0.000 claims 1
- TZXGHCSBXVYIGW-UHFFFAOYSA-N 5-chloro-2-(3-ethyl-2-methyl-5-nitroimidazol-4-yl)sulfanylpyridine Chemical compound CCN1C(C)=NC([N+]([O-])=O)=C1SC1=CC=C(Cl)C=N1 TZXGHCSBXVYIGW-UHFFFAOYSA-N 0.000 claims 1
- KLVOYOMLAVRBSH-UHFFFAOYSA-N 6-(4-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazole Chemical compound C1=CC(C)=CC=C1C1=CN(N=CS2)C2=N1 KLVOYOMLAVRBSH-UHFFFAOYSA-N 0.000 claims 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims 1
- 229930091371 Fructose Natural products 0.000 claims 1
- 239000005715 Fructose Substances 0.000 claims 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- VDANFBQXJIQYEQ-UHFFFAOYSA-N n-[4-(4-ethylphenyl)-1,3-thiazol-2-yl]-3,5-dimethoxybenzamide Chemical compound C1=CC(CC)=CC=C1C1=CSC(NC(=O)C=2C=C(OC)C=C(OC)C=2)=N1 VDANFBQXJIQYEQ-UHFFFAOYSA-N 0.000 claims 1
- YOFAHJGHHKJJBE-UHFFFAOYSA-N n-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)-1,4-diazepane-1-carboxamide Chemical compound C1CCN(C=2SN=C(N=2)C=2C=CC=CC=2)CCN1C(=O)NC1=CC=CC=C1 YOFAHJGHHKJJBE-UHFFFAOYSA-N 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 6
- 125000005915 C6-C14 aryl group Chemical group 0.000 abstract 4
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
- A23L27/204—Aromatic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/20—Synthetic spices, flavouring agents or condiments
- A23L27/205—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/88—Taste or flavour enhancing agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Seasonings (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- General Preparation And Processing Of Foods (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83911806P | 2006-08-22 | 2006-08-22 | |
| US60/839,118 | 2006-08-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2009101298A true RU2009101298A (ru) | 2010-09-27 |
Family
ID=39107364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2009101298/21A RU2009101298A (ru) | 2006-08-22 | 2007-08-22 | Гетероциклические соединения в качестве усилителей подслащивающего вещества |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7674831B2 (enExample) |
| EP (1) | EP2061321A2 (enExample) |
| JP (1) | JP2010501180A (enExample) |
| KR (1) | KR20090053795A (enExample) |
| CN (1) | CN101505601A (enExample) |
| AU (1) | AU2007288220A1 (enExample) |
| BR (1) | BRPI0716053A2 (enExample) |
| CA (1) | CA2659465A1 (enExample) |
| MX (1) | MX2009001783A (enExample) |
| NO (1) | NO20091170L (enExample) |
| RU (1) | RU2009101298A (enExample) |
| SG (1) | SG160335A1 (enExample) |
| WO (1) | WO2008024364A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008024364A2 (en) * | 2006-08-22 | 2008-02-28 | Redpoint Bio Corporation | Heterocyclic compounds as sweetener enhancers |
| US20080292765A1 (en) * | 2007-05-22 | 2008-11-27 | The Coca-Cola Company | Sweetness Enhancers, Sweetness Enhanced Sweetener Compositions, Methods for Their Formulation, and Uses |
| AU2013202912B2 (en) * | 2007-06-08 | 2016-10-27 | Firmenich Incorporated | Modulation of chemosensory receptors and ligands associated therewith |
| US9603848B2 (en) | 2007-06-08 | 2017-03-28 | Senomyx, Inc. | Modulation of chemosensory receptors and ligands associated therewith |
| US8043645B2 (en) | 2008-07-09 | 2011-10-25 | Starbucks Corporation | Method of making beverages with enhanced flavors and aromas |
| EP3085699B1 (en) | 2008-07-31 | 2022-03-02 | Firmenich Incorporated | Processes for making sweet taste enhancers |
| PL216572B1 (pl) * | 2009-02-02 | 2014-04-30 | Inst Chemii Organicznej Polska Akademia Nauk | Związki enaminokarbonylowe i ich zastosowanie |
| US20130040032A1 (en) * | 2009-02-23 | 2013-02-14 | Kyle Thibault | Horse Treats |
| MX2012011996A (es) * | 2010-04-15 | 2013-11-27 | Chromocell Corp | Compuestos , composiciones y metodos para reducir o eliminar el sabor amargo. |
| EP2667885B1 (en) * | 2011-01-25 | 2018-08-08 | Monell Chemical Senses Center | Compositions and methods for providing or modulating sweet taste and methods of screening therefor |
| JP5848083B2 (ja) * | 2011-09-30 | 2016-01-27 | 三栄源エフ・エフ・アイ株式会社 | 高甘味度甘味料の味質改善剤 |
| CN103156154A (zh) * | 2011-12-09 | 2013-06-19 | 味之素株式会社 | 甜味剂组合物以及饮料食品 |
| RU2018129982A (ru) * | 2012-08-06 | 2019-03-15 | Сеномикс, Инк. | Модификатор сладкого вкуса и аромата |
| JO3155B1 (ar) | 2013-02-19 | 2017-09-20 | Senomyx Inc | معدِّل نكهة حلوة |
| EP2832234A1 (en) * | 2013-07-30 | 2015-02-04 | IMAX Discovery GmbH | Imidazo[1,2-a]pyridine-ylmethyl-derivatives and their use as flavoring agents |
| CN103524419B (zh) * | 2013-10-18 | 2016-03-23 | 孙家隆 | 一组3-三氟甲基吡唑化合物 |
| US10595550B2 (en) * | 2014-01-22 | 2020-03-24 | Vision Pharma, Llc | Therapeutic composition including carbonated solution |
| MX2021001193A (es) | 2018-08-07 | 2021-04-28 | Firmenich Incorporated | 2,2-dioxidos de 4-amino-1h-benzo[c][1,2,6]tiadiazina 5-sustituidos y formulaciones y usos de los mismos. |
| KR102650658B1 (ko) * | 2018-11-15 | 2024-03-25 | 삼성전자주식회사 | 헤테로고리 방향족 구조의 음이온을 포함하는 금속염 및 그 제조방법, 그리고 상기 금속염을 포함하는 전해질 및 전기화학소자 |
| TWI775313B (zh) | 2020-02-18 | 2022-08-21 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| AU2021224588B2 (en) | 2020-02-18 | 2024-07-18 | Gilead Sciences, Inc. | Antiviral compounds |
| TWI883391B (zh) | 2020-02-18 | 2025-05-11 | 美商基利科學股份有限公司 | 抗病毒化合物 |
| KR20230170745A (ko) | 2021-04-16 | 2023-12-19 | 길리애드 사이언시즈, 인코포레이티드 | 아미드를 사용한 카르바뉴클레오시드를 제조하는 방법 |
| US12116380B2 (en) | 2021-08-18 | 2024-10-15 | Gilead Sciences, Inc. | Phospholipid compounds and methods of making and using the same |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2978405A (en) * | 1959-06-18 | 1961-04-04 | Sun Oil Co | Oxidative sweetening with alkaline material and imidazole derivative |
| US4056108A (en) * | 1975-05-19 | 1977-11-01 | R. J. Reynolds Tobacco Company | Tobacco product |
| US4684534A (en) * | 1985-02-19 | 1987-08-04 | Dynagram Corporation Of America | Quick-liquifying, chewable tablet |
| US5196224A (en) * | 1985-09-16 | 1993-03-23 | Naarden-International N.V. | Substituted thiophenes, and flavoring and perfume compositions and flavored and perfumed products which contain one or more substituted thiophenes |
| US5011678A (en) * | 1989-02-01 | 1991-04-30 | California Biotechnology Inc. | Composition and method for administration of pharmaceutically active substances |
| US6649186B1 (en) * | 1996-09-20 | 2003-11-18 | Ethypharm | Effervescent granules and methods for their preparation |
| US6368625B1 (en) * | 1998-08-12 | 2002-04-09 | Cima Labs Inc. | Orally disintegrable tablet forming a viscous slurry |
| US6060078A (en) * | 1998-09-28 | 2000-05-09 | Sae Han Pharm Co., Ltd. | Chewable tablet and process for preparation thereof |
| US6403142B1 (en) * | 1998-12-11 | 2002-06-11 | Ralston Purina Company | Hypoallergenic pet food |
| US6773716B2 (en) * | 1999-04-06 | 2004-08-10 | Wm. Wrigley Jr. Company | Over-coated chewing gum formulations |
| US6187332B1 (en) * | 1999-06-14 | 2001-02-13 | Wisconsin Alumni Research Foundation | Acidic buffered nasal spray |
| US6316029B1 (en) * | 2000-05-18 | 2001-11-13 | Flak Pharma International, Ltd. | Rapidly disintegrating solid oral dosage form |
| US20070104709A1 (en) * | 2003-08-06 | 2007-05-10 | Xiaodong Li | T1r hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds |
| US20060045953A1 (en) * | 2004-08-06 | 2006-03-02 | Catherine Tachdjian | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers |
| WO2008024364A2 (en) * | 2006-08-22 | 2008-02-28 | Redpoint Bio Corporation | Heterocyclic compounds as sweetener enhancers |
-
2007
- 2007-08-22 WO PCT/US2007/018511 patent/WO2008024364A2/en not_active Ceased
- 2007-08-22 KR KR1020097003759A patent/KR20090053795A/ko not_active Withdrawn
- 2007-08-22 SG SG201001218-5A patent/SG160335A1/en unknown
- 2007-08-22 US US11/843,411 patent/US7674831B2/en not_active Expired - Fee Related
- 2007-08-22 BR BRPI0716053-4A patent/BRPI0716053A2/pt not_active IP Right Cessation
- 2007-08-22 JP JP2009525610A patent/JP2010501180A/ja not_active Withdrawn
- 2007-08-22 MX MX2009001783A patent/MX2009001783A/es not_active Application Discontinuation
- 2007-08-22 CN CNA2007800309475A patent/CN101505601A/zh active Pending
- 2007-08-22 EP EP07837168A patent/EP2061321A2/en not_active Withdrawn
- 2007-08-22 RU RU2009101298/21A patent/RU2009101298A/ru not_active Application Discontinuation
- 2007-08-22 CA CA002659465A patent/CA2659465A1/en not_active Abandoned
- 2007-08-22 AU AU2007288220A patent/AU2007288220A1/en not_active Abandoned
-
2009
- 2009-03-19 NO NO20091170A patent/NO20091170L/no not_active Application Discontinuation
-
2010
- 2010-02-09 US US12/702,921 patent/US20100197813A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20080249189A1 (en) | 2008-10-09 |
| KR20090053795A (ko) | 2009-05-27 |
| AU2007288220A1 (en) | 2008-02-28 |
| EP2061321A2 (en) | 2009-05-27 |
| MX2009001783A (es) | 2009-02-25 |
| WO2008024364A3 (en) | 2008-11-13 |
| US20100197813A1 (en) | 2010-08-05 |
| WO2008024364A2 (en) | 2008-02-28 |
| CA2659465A1 (en) | 2008-02-28 |
| BRPI0716053A2 (pt) | 2013-08-06 |
| SG160335A1 (en) | 2010-04-29 |
| US7674831B2 (en) | 2010-03-09 |
| JP2010501180A (ja) | 2010-01-21 |
| CN101505601A (zh) | 2009-08-12 |
| NO20091170L (no) | 2009-05-22 |
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